Author: David C Glahn

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Preprints

The genetic architecture of the human cerebral cortex

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  • In genetics: 35
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Exome sequencing identifies rare coding variants in 10 genes which confer substantial risk for schizophrenia

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  • Site-wide: 1,674
  • In genetic and genomic medicine: 10
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  • Site-wide: 664
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Brain charts for the human lifespan

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  • In neuroscience: 148
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GWAS meta-analysis (N=279,930) identifies new genes and functional links to intelligence

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  • Site-wide: 2,680
  • In genetics: 71
• Year to date:
  • Site-wide: 29,165
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  • Site-wide: 23,166

Greater male than female variability in regional brain structure across the lifespan

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  • In neuroscience: 313
• Year to date:
  • Site-wide: 57,982
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Ninety-nine independent genetic loci influencing general cognitive function include genes associated with brain health and structure (N = 280,360)

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  • Site-wide: 5,324
  • In genetics: 172
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  • Site-wide: 70,367
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Whole Genome Sequencing in Psychiatric Disorders: the WGSPD Consortium

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  • Site-wide: 13,677
  • In genomics: 1,240
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Mapping Cortical Brain Asymmetry in 17,141 Healthy Individuals Worldwide via the ENIGMA Consortium

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  • Site-wide: 17,415
  • In neuroscience: 1,787
• Year to date:
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  • Site-wide: 160,756

The correspondence problem: which brain maps are significantly similar?

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  • Site-wide: 20,703
  • In neuroscience: 2,264
• Year to date:
  • Site-wide: 83,975
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  • Site-wide: 108,617

Cortical Thickness Trajectories across the Lifespan: Data from 17,075 healthy individuals aged 3-90 years

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  • Site-wide: 23,857
  • In neuroscience: 2,750
• Year to date:
  • Site-wide: 77,913
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  • Site-wide: 123,108

Do Candidate Genes Affect the Brain's White Matter Microstructure? Large-Scale Evaluation of 6,165 Diffusion MRI Scans

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  • Site-wide: 35,763
  • In neuroscience: 4,463
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  • Site-wide: 85,709
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  • Site-wide: 57,772

Planar cell polarity pathway and development of the human visual cortex

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  • Site-wide: 36,747
  • In neuroscience: 4,615
• Year to date:
  • Site-wide: 78,870
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  • Site-wide: 54,790

Efficient variant set mixed model association tests for continuous and binary traits in large-scale whole genome sequencing studies

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  • Site-wide: 40,106
  • In genetics: 1,563
• Year to date:
  • Site-wide: 178,900
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  • Site-wide: 160,202

Subcortical Volume Trajectories across the Lifespan: Data from 18,605 healthy individuals aged 3-90 years

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  • Site-wide: 40,820
  • In neuroscience: 5,094
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  • Site-wide: 124,772
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Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways

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  • Site-wide: 45,660
  • In genetics: 1,774
• Year to date:
  • Site-wide: 160,738
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  • Site-wide: 133,403

Effects-sizes of deletions and duplications on autism risk across the genome

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  • Site-wide: 47,130
  • In genetics: 1,923
• Year to date:
  • Site-wide: 77,843
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  • Site-wide: 98,315

Common variants of NRXN1, LRP1B and RORA are associated with increased ventricular volumes in psychosis - GWAS findings from the B-SNIP deep phenotyping study

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  • Site-wide: 47,528
  • In genetics: 1,920
• Year to date:
  • Site-wide: 89,691
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  • Site-wide: 65,155

Atlas of functional connectivity relationships across rare and common genetic variants, traits, and psychiatric conditions

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  • Site-wide: 47,709
  • In genetic and genomic medicine: 286
• Year to date:
  • Site-wide: 28,261
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  • Site-wide: 49,063

Large-Scale cognitive GWAS Meta-analysis Reveals Tissue-Specific Neural Expression and Potential Nootopic Drug Targets

• Downloaded 761 times
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  • Site-wide: 51,084
  • In genomics: 3,602
• Year to date:
  • Site-wide: 155,542
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  • Site-wide: 131,465

Stability of Polygenic Scores Across Discovery Genome-Wide Association Studies

• Downloaded 760 times
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  • Site-wide: 51,211
  • In genetics: 2,055
• Year to date:
  • Site-wide: 79,888
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  • Site-wide: 114,693

Altered structural brain asymmetry in autism spectrum disorder: large-scale analysis via the ENIGMA Consortium

• Downloaded 742 times
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  • Site-wide: 52,997
  • In neuroscience: 7,074
• Year to date:
  • Site-wide: 104,220
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  • Site-wide: 109,201

Fast and Powerful Genome Wide Association Analysis of Dense Genetic Data with High Dimensional Imaging Phenotypes

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  • Site-wide: 56,528
  • In genetics: 2,161
• Year to date:
  • Site-wide: 170,187
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  • Site-wide: 159,222

Identifying Nootropic Drug Targets via Large-Scale Cognitive GWAS and Transcriptomics

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  • Site-wide: 56,762
  • In genomics: 4,024
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  • Site-wide: 92,932

The reliability and heritability of cortical folds and their genetic correlations across hemispheres

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  • Site-wide: 86,628
  • In genetics: 3,322
• Year to date:
  • Site-wide: 156,202
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  • Site-wide: 151,357

The architecture of co-morbidity networks of physical and mental health conditions in military veterans

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  • Site-wide: 93,829
  • In health informatics: 361
• Year to date:
  • Site-wide: 147,429
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  • Site-wide: 123,665

Structural brain architectures match intrinsic functional networks and vary across domains: A study from 15000+ individuals

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  • Site-wide: 109,058
  • In neuroscience: 14,721
• Year to date:
  • Site-wide: 190,986
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  • Site-wide: 190,617

Analysis of structural brain asymmetries in Attention-Deficit/Hyperactivity Disorder in 39 datasets

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  • Site-wide: 117,010
  • In neuroscience: 16,173
• Year to date:
  • Site-wide: 158,202
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  • Site-wide: 177,565

Large-scale analysis of structural brain asymmetries in schizophrenia via the ENIGMA consortium

• Downloaded 369 times
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  • Site-wide: 119,037
  • In psychiatry and clinical psychology: None
• Year to date:
  • Site-wide: 8,138
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  • Site-wide: 29,065

A rare variant in D-amino acid oxidase implicates NMDA receptor signaling and cerebellar gene networks in risk for bipolar disorder

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  • Site-wide: 142,121
  • In psychiatry and clinical psychology: 759
• Year to date:
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  • Site-wide: 73,844

Dissociable Cellular and Genetic Mechanisms of Cortical Thinning at Different Life Stages

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  • Site-wide: 167,348
  • In neuroscience: None
• Year to date:
  • Site-wide: 20,573
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  • Site-wide: 36,322

Rare CNVs and phenome-wide profiling: a tale of brain-structural divergence and phenotypical convergence

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  • Site-wide: 175,796
  • In genetics: None
• Year to date:
  • Site-wide: 27,066
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  • Site-wide: 13,399

Genome-wide significant risk loci for mood disorders in the Old Order Amish founder population

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  • Site-wide: 179,613
  • In psychiatry and clinical psychology: 1,192
• Year to date:
  • Site-wide: 31,684
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  • Site-wide: 53,273