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Author: Ian J Deary

Rankings

  • All-time downloads: 97,482 (rank: 1,489 )
  • Categories:
    • bioinformatics: 1,372 (rank: 12,000 (tie) )
    • cell biology: 847 (rank: 12,259 (tie) )
    • epidemiology: 6,226 (rank: 2,554 )
    • genetic and genomic medicine: 806 (rank: 4,363 (tie) )
    • genetics: 45,406 (rank: 97 )
    • genomics: 6,783 (rank: 3,425 )
    • geriatric medicine: 383 (rank: 396 (tie) )
    • neurology: 847 (rank: 1,690 (tie) )
    • neuroscience: 33,449 (rank: 147 )
    • psychiatry and clinical psychology: 744 (rank: 1,659 (tie) )
    • radiology and imaging: 619 (rank: 769 (tie) )

Downloads per author, site-wide

Preprints

Topological relationships between perivascular spaces and progression of white matter hyperintensities: a pilot study in a sample of the Lothian Birth Cohort 1936

cardiovascular medicine more details view paper

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Sex Differences In The Adult Human Brain: Evidence From 5,216 UK Biobank Participants

neuroscience more details view paper
  • Downloaded 26,289 times
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    • Site-wide: 297
    • In neuroscience: 7
  • Year to date:
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  • Since beginning of last month:
    • Site-wide: 41,205

GWAS meta-analysis (N=279,930) identifies new genes and functional links to intelligence

genetics more details view paper
  • Downloaded 5,366 times
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    • Site-wide: 2,194
    • In genetics: 69
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    • Site-wide: 21,399
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Genomic SEM Provides Insights into the Multivariate Genetic Architecture of Complex Traits

genetics more details view paper
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    • Site-wide: 2,673
    • In genetics: 87
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Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions.

genetics more details view paper
  • Downloaded 4,611 times
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    • Site-wide: 2,699
    • In genetics: 88
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Genomic analysis of family data reveals additional genetic effects on intelligence and personality

genetics more details view paper
  • Downloaded 4,269 times
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    • Site-wide: 3,028
    • In genetics: 99
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    • Site-wide: 46,779
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    • Site-wide: 105,660

Ninety-nine independent genetic loci influencing general cognitive function include genes associated with brain health and structure (N = 280,360)

genetics more details view paper
  • Downloaded 3,352 times
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    • Site-wide: 4,221
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    • Site-wide: 44,744
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    • Site-wide: 22,622

Psychosocial factors and hospitalisations for COVID-19: Prospective cohort study of the general population

epidemiology more details view paper
  • Downloaded 2,666 times
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    • Site-wide: 5,832
    • In epidemiology: 518
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Genome-wide association study of depression phenotypes in UK Biobank (n = 322,580) identifies the enrichment of variants in excitatory synaptic pathways

genetics more details view paper
  • Downloaded 2,631 times
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    • Site-wide: 5,944
    • In genetics: 248
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    • Site-wide: 76,921
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    • Site-wide: 71,345

Shared genetic aetiology between cognitive functions and physical and mental health in UK Biobank (N = 112 151) and 24 GWAS consortia.

genetics more details view paper
  • Downloaded 1,794 times
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    • Site-wide: 10,487
    • In genetics: 458
  • Year to date:
    • Site-wide: 129,634
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    • Site-wide: None

Genome-wide association study meta-analysis of the Alcohol Use Disorder Identification Test (AUDIT) in two population-based cohorts (N=141,932)

genetics more details view paper
  • Downloaded 1,789 times
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    • Site-wide: 10,537
    • In genetics: 462
  • Year to date:
    • Site-wide: 53,057
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    • Site-wide: 22,452

Genetic Associations with Subjective Well-Being Also Implicate Depression and Neuroticism

genetics more details view paper
  • Downloaded 1,755 times
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    • Site-wide: 10,830
    • In genetics: 478
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    • Site-wide: 90,449
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Molecular genetic contributions to social deprivation and household income in UK Biobank (n = 112,151)

genetics more details view paper
  • Downloaded 1,655 times
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    • Site-wide: 11,804
    • In genetics: 531
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    • Site-wide: 102,722
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    • Site-wide: 120,086

Genetic contribution to two factors of neuroticism is associated with affluence, better health, and longer life

genetics more details view paper
  • Downloaded 1,532 times
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    • Site-wide: 13,139
    • In genetics: 595
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    • Site-wide: 102,587
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116 independent genetic variants influence the neuroticism personality trait in over 329,000 UK Biobank individuals.

genetics more details view paper
  • Downloaded 1,492 times
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    • Site-wide: 13,718
    • In genetics: 625
  • Year to date:
    • Site-wide: 43,274
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    • Site-wide: 19,688

Improved prediction of chronological age from DNA methylation limits it as a biomarker of ageing

bioinformatics more details view paper
  • Downloaded 1,372 times
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    • Site-wide: 15,634
    • In bioinformatics: 1,810
  • Year to date:
    • Site-wide: 66,293
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    • Site-wide: 105,008

Bayesian reassessment of the epigenetic architecture of complex traits

genomics more details view paper
  • Downloaded 1,352 times
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    • Site-wide: 15,972
    • In genomics: 1,580
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    • Site-wide: 128,896
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    • Site-wide: 45,247

Education, intelligence and Alzheimer's disease: Evidence from a multivariable two-sample Mendelian randomization study

genetics more details view paper
  • Downloaded 1,069 times
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    • Site-wide: 22,610
    • In genetics: 1,029
  • Year to date:
    • Site-wide: 119,057
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    • Site-wide: None

Epigenetic prediction of complex traits and death

genomics more details view paper
  • Downloaded 1,028 times
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    • Site-wide: 23,942
    • In genomics: 2,247
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    • Site-wide: 102,558
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Reliability and validity of the UK Biobank cognitive tests

epidemiology more details view paper
  • Downloaded 998 times
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    • Site-wide: 25,006
    • In epidemiology: 1,458
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    • Site-wide: 56,110
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Tissue-Specific Alteration of Metabolic Pathways Influences Glycemic Regulation

genetics more details view paper
  • Downloaded 993 times
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    • Site-wide: 25,192
    • In genetics: 1,144
  • Year to date:
    • Site-wide: 25,875
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    • Site-wide: 114,557

Polygenic architecture of human neuroanatomical diversity

neuroscience more details view paper
  • Downloaded 940 times
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    • Site-wide: 27,266
    • In neuroscience: 3,475
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    • Site-wide: 51,779
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    • Site-wide: 111,357

Is there association between APOE e4 genotype and structural brain ageing phenotypes, and does that association increase in older age in UK Biobank? (N = 8,395)

genetics more details view paper
  • Downloaded 908 times
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    • Site-wide: 28,676
    • In genetics: 1,311
  • Year to date:
    • Site-wide: 123,163
  • Since beginning of last month:
    • Site-wide: 120,281

A phenome-wide association and Mendelian Randomisation study of polygenic risk for depression in UK Biobank

genetics more details view paper
  • Downloaded 877 times
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    • Site-wide: 30,099
    • In genetics: 1,374
  • Year to date:
    • Site-wide: 143,100
  • Since beginning of last month:
    • Site-wide: 110,896

Do Candidate Genes Affect the Brain's White Matter Microstructure? Large-Scale Evaluation of 6,165 Diffusion MRI Scans

neuroscience more details view paper
  • Downloaded 858 times
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    • Site-wide: 31,051
    • In neuroscience: 4,027
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    • Site-wide: 119,122
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    • Site-wide: 106,214

Longitudinal dynamics of clonal hematopoiesis identifies gene-specific fitness effects

cell biology more details view paper
  • Downloaded 847 times
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    • Site-wide: 31,582
    • In cell biology: 1,196
  • Year to date:
    • Site-wide: 4,360
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    • Site-wide: 1,697

Planar cell polarity pathway and development of the human visual cortex

neuroscience more details view paper
  • Downloaded 814 times
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    • Site-wide: 33,353
    • In neuroscience: 4,374
  • Year to date:
    • Site-wide: 79,156
  • Since beginning of last month:
    • Site-wide: 114,914

Novel blood pressure locus and gene discovery using GWAS and expression datasets from blood and the kidney

genomics more details view paper
  • Downloaded 786 times
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    • Site-wide: 35,091
    • In genomics: 2,963
  • Year to date:
    • Site-wide: 106,725
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    • Site-wide: 51,707

Pre-pandemic Cognitive Function and COVID-19 Vaccine Hesitancy: Prospective Cohort Study

epidemiology more details view paper
  • Downloaded 764 times
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    • Site-wide: 36,567
    • In epidemiology: 1,868
  • Year to date:
    • Site-wide: 5,040
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    • Site-wide: 6,844

Do Regional Brain Volumes and Major Depressive Disorder Share Genetic Architecture: a study in Generation Scotland (n=19,762), UK Biobank (n=24,048) and the English Longitudinal Study of Ageing (n=5,766)

genetics more details view paper
  • Downloaded 763 times
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    • Site-wide: 36,600
    • In genetics: 1,650
  • Year to date:
    • Site-wide: 133,558
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    • Site-wide: 78,247

Genome-Wide Meta-Analyses Of Stratified Depression In Generation Scotland And UK Biobank

genetics more details view paper
  • Downloaded 740 times
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    • Site-wide: 38,195
    • In genetics: 1,717
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    • Site-wide: 147,718
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    • Site-wide: 120,202

Stratifying depression by neuroticism: revisiting a diagnostic tradition using GWAS data

genetics more details view paper
  • Downloaded 711 times
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    • Site-wide: 40,296
    • In genetics: 1,809
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    • Site-wide: 95,972
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Associations between vascular risk factors and brain MRI indices in UK Biobank

neuroscience more details view paper
  • Downloaded 708 times
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    • Site-wide: 40,501
    • In neuroscience: 5,539
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    • Site-wide: 121,920
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Generalisability of Results from UK Biobank: Comparison With a Pooling of 18 Cohort Studies

epidemiology more details view paper
  • Downloaded 704 times
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    • Site-wide: 40,782
    • In epidemiology: 2,036
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    • Site-wide: 48,267
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    • Site-wide: 87,699

Epigenetic influences on aging: a longitudinal genome-wide methylation study in old Swedish twins

genetics more details view paper
  • Downloaded 701 times
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    • Site-wide: 41,040
    • In genetics: 1,844
  • Year to date:
    • Site-wide: 116,987
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    • Site-wide: 36,969

Epigenetic scores for the circulating proteome as tools for disease prediction

genomics more details view paper
  • Downloaded 663 times
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    • Site-wide: 44,193
    • In genomics: 3,514
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    • Site-wide: 8,313
  • Since beginning of last month:
    • Site-wide: 6,546

Genetic and environmental risk for chronic pain and the contribution of risk variants for psychiatric disorders. Results from Generation Scotland: Scottish Family Health Study and UK Biobank

genomics more details view paper
  • Downloaded 661 times
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    • Site-wide: 44,372
    • In genomics: 3,525
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    • Site-wide: 137,766
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    • Site-wide: 80,950

Novel Locus Influencing Retinal Venular Tortuosity Is Also Associated With Risk Of Coronary Artery Disease

genomics more details view paper
  • Downloaded 655 times
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    • Site-wide: 44,918
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    • Site-wide: 115,466
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Rare disruptive variants in the DISC1 Interactome and Regulome: association with cognitive ability and schizophrenia

genetics more details view paper
  • Downloaded 625 times
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    • Site-wide: 47,695
    • In genetics: 2,126
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    • Site-wide: 26,585
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Cognitive ability and physical health: a Mendelian randomization study

genetics more details view paper
  • Downloaded 617 times
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    • Site-wide: 48,450
    • In genetics: 2,159
  • Year to date:
    • Site-wide: 148,510
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Identifying Nootropic Drug Targets via Large-Scale Cognitive GWAS and Transcriptomics

genomics more details view paper
  • Downloaded 602 times
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    • Site-wide: 49,937
    • In genomics: 3,838
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    • Site-wide: 56,613
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    • Site-wide: 66,480

Meta-analysis of exome array data identifies six novel genetic loci for lung function

genetics more details view paper
  • Downloaded 483 times
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    • Site-wide: 64,862
    • In genetics: 2,855
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    • Site-wide: 150,511
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Resting-state connectivity and its association with cognitive performance, educational attainment, and household income in UK Biobank (N = 3,950)

neuroscience more details view paper
  • Downloaded 478 times
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    • Site-wide: 65,636
    • In neuroscience: 9,573
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    • Site-wide: 149,507
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    • Site-wide: 118,277

Common genetic variation indicates separate etiologies for periventricular and deep white matter hyperintensities

neuroscience more details view paper
  • Downloaded 474 times
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    • Site-wide: 66,182
    • In neuroscience: 9,684
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    • Site-wide: 108,237
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    • Site-wide: 122,737

Psychotic-like experiences, polygenic risk scores for schizophrenia and structural properties of the salience, default mode and central-executive networks in healthy participants from UK Biobank

neuroscience more details view paper
  • Downloaded 449 times
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    • Site-wide: 70,224
    • In neuroscience: 10,307
  • Year to date:
    • Site-wide: 82,857
  • Since beginning of last month:
    • Site-wide: 9,027

Cognitive impairments in sporadic cerebral small vessel disease (SVD): a systematic review and meta-analysis of cohorts with stroke, dementia and non-clinical presentations of SVD

neurology more details view paper
  • Downloaded 444 times
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    • Site-wide: 71,095
    • In neurology: 178
  • Year to date:
    • Site-wide: 88,368
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    • Site-wide: 82,724

Epigenetic prediction of major depressive disorder

psychiatry and clinical psychology more details view paper
  • Downloaded 443 times
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    • Site-wide: 71,110
    • In psychiatry and clinical psychology: 251
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    • Site-wide: 120,063
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    • Site-wide: 82,567

A genome-wide association study finds novel genetic associations with broadly-defined headache in UK Biobank (N = 223,773)

genetics more details view paper
  • Downloaded 438 times
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    • Site-wide: 71,988
    • In genetics: 3,159
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    • Site-wide: 133,481
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    • Site-wide: 59,220

Retinal microvasculature and cerebral small vessel disease in the Lothian Birth Cohort 1936 and Mild Stroke Study

neuroscience more details view paper
  • Downloaded 420 times
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    • Site-wide: 75,085
    • In neuroscience: 11,114
  • Year to date:
    • Site-wide: 153,652
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    • Site-wide: None

SNPs associated with HHIP expression have differential effects on lung function in males and females

genetics more details view paper
  • Downloaded 417 times
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    • Site-wide: 75,562
    • In genetics: 3,298
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    • Site-wide: 116,812
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    • Site-wide: 62,725

Characterisation of an inflammation-related epigenetic score and its association with cognitive ability

genomics more details view paper
  • Downloaded 411 times
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    • Site-wide: 76,763
    • In genomics: 5,146
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    • Site-wide: 140,143
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    • Site-wide: 115,222

An epigenetic proxy of chronic inflammation outperforms serum levels as a biomarker of brain ageing

neurology more details view paper
  • Downloaded 403 times
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    • Site-wide: 78,112
    • In neurology: 214
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    • Site-wide: 32,356
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    • Site-wide: 74,886

The influence of X chromosome variants on trait neuroticism.

genetics more details view paper
  • Downloaded 391 times
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    • Site-wide: 80,478
    • In genetics: 3,491
  • Year to date:
    • Site-wide: 144,180
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    • Site-wide: 115,016

An epigenetic predictor of death captures multi-modal measures of brain health

neuroscience more details view paper
  • Downloaded 390 times
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    • Site-wide: 80,533
    • In neuroscience: 11,988
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    • Site-wide: 141,659
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    • Site-wide: 63,558

Blood pressure and cognitive function across the eighth decade: a prospective study of the Lothian Birth Cohort of 1936

geriatric medicine more details view paper
  • Downloaded 383 times
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    • Site-wide: 81,908
    • In geriatric medicine: 50
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    • Site-wide: 132,043
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    • Site-wide: 74,594

Understanding Cognitive Impairment in Mood Disorders: Mediation Analyses in the UK Biobank Cohort

epidemiology more details view paper
  • Downloaded 361 times
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    • Site-wide: 86,386
    • In epidemiology: 3,676
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    • Site-wide: 147,411
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    • Site-wide: 70,174

Association of whole-genome and NETRIN1 signaling pathway-derived polygenic risk scores for Major Depressive Disorder and thalamic radiation white matter microstructure in UK Biobank

genetics more details view paper
  • Downloaded 351 times
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    • Site-wide: 88,340
    • In genetics: 3,828
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    • Site-wide: 150,528
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    • Site-wide: None

An epigenome-wide association study of sex-specific chronological ageing

genomics more details view paper
  • Downloaded 336 times
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    • Site-wide: 91,583
    • In genomics: 5,741
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    • Site-wide: 152,960
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Brain peak width of skeletonised mean diffusivity (PSMD), processing speed, and other cognitive domains

neuroscience more details view paper
  • Downloaded 298 times
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    • Site-wide: 100,359
    • In neuroscience: 15,093
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    • Site-wide: 129,691
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    • Site-wide: 119,718

Childhood coordination and survival up to six decades later: extended follow-up of participants in the National Child Development Study

epidemiology more details view paper
  • Downloaded 290 times
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    • Site-wide: 102,016
    • In epidemiology: 4,306
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    • Site-wide: 89,831
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    • Site-wide: 25,499

Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure

genomics more details view paper
  • Downloaded 289 times
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    • Site-wide: 102,387
    • In genomics: 6,141
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    • Site-wide: 69,501
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    • Site-wide: 89,004

Quantitative Measurements of Enlarged Perivascular Spaces in the Brain are Associated with Retinal Microvascular Parameters in Older Community-Dwelling Subjects

neuroscience more details view paper
  • Downloaded 284 times
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    • Site-wide: 103,499
    • In neuroscience: 15,633
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    • Site-wide: 123,933
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    • Site-wide: 109,446

Age and mortality associated DNA methylation patterns on the X-chromosome in male and female samples

genetics more details view paper
  • Downloaded 276 times
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    • Site-wide: 105,448
    • In genetics: 4,480
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    • Site-wide: 122,912
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    • Site-wide: 45,186

DNA methylation outlier burden, health and ageing in Generation Scotland and the Lothian Birth Cohorts of 1921 and 1936.

genetic and genomic medicine more details view paper
  • Downloaded 272 times
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    • Site-wide: 106,375
    • In genetic and genomic medicine: 521
  • Year to date:
    • Site-wide: 108,989
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    • Site-wide: 74,316

Health literacy, cognitive ability and self-reported diabetes in the English Longitudinal Study of Ageing

epidemiology more details view paper
  • Downloaded 248 times
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    • Site-wide: 112,310
    • In epidemiology: 4,712
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    • Site-wide: 107,729
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    • Site-wide: None

Spatial Gradient of Microstructural Changes in Normal-Appearing White Matter in Tracts Affected by White Matter Hyperintensities in Older Age

neuroscience more details view paper
  • Downloaded 237 times
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    • Site-wide: 115,073
    • In neuroscience: 17,417
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    • Site-wide: 147,973
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    • Site-wide: 114,701

Stratifying major depressive disorder by polygenic risk for schizophrenia in relation to structural brain measures

neuroscience more details view paper
  • Downloaded 231 times
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    • Site-wide: 116,621
    • In neuroscience: 17,649
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    • Site-wide: 153,495
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    • Site-wide: None

DNA methylation in the APOE gene: its link with Alzheimer's and cardiovascular health

neuroscience more details view paper
  • Downloaded 226 times
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    • Site-wide: 117,947
    • In neuroscience: 17,805
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    • Site-wide: 149,766
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    • Site-wide: 115,790

Associations between total MRI-visible small vessel disease burden and domain-specific cognitive abilities in a community-dwelling older-age cohort

radiology and imaging more details view paper
  • Downloaded 221 times
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    • Site-wide: 119,265
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    • Site-wide: 29,459
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    • Site-wide: 101,134

A comparison of blood and brain-derived ageing and inflammation-related DNA methylation signatures and their association with microglial burdens

neuroscience more details view paper
  • Downloaded 217 times
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    • Site-wide: 120,180
    • In neuroscience: 18,172
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    • Site-wide: 62,332
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    • Site-wide: 30,081

Blood-based epigenome-wide analyses of cognitive abilities

genetic and genomic medicine more details view paper
  • Downloaded 199 times
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    • Site-wide: 124,594
    • In genetic and genomic medicine: 669
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    • Site-wide: 33,358
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Life course air pollution exposure and cognitive decline: modelled historical air pollution data and the Lothian Birth Cohort 1936

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The Influence of Phenotyping Method on Neuroimaging Associations with Depression in UK Biobank

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Methylome-wide association study of early life stressors and adult mental health reveals a relationship between birth date and cell type composition in blood

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Genome and epigenome wide studies of plasma protein biomarkers for Alzheimer's disease implicate TBCA and TREM2 in disease risk

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Comparison of structural MRI brain measures between 1.5T and 3T: data from the Lothian Birth Cohort 1936

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Local CpG density affects the trajectory of age-associated epigenetic changes

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Birth weight is associated with brain tissue volumes seven decades later, but not with age-associated changes to brain structure

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Cerebral Small Vessel Disease Burden and Longitudinal Cognitive Decline from age 73 to 82: the Lothian Birth Cohort 1936

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DNA methylome-wide association study of genetic risk for depression implicates antigen processing and immune responses

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Contribution of white matter hyperintensities to ventricular enlargement in older adults

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