Author: Ming Hu

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Preprints

Caution on Kidney Dysfunctions of 2019-nCoV Patients

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  • Site-wide: 641
  • In infectious diseases: 199
• Year to date:
  • Site-wide: 3,243
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  • Site-wide: 3,243

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

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  • Site-wide: 812
  • In genetics: 25
• Year to date:
  • Site-wide: 22,219
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  • Site-wide: 22,219

The 3D Genome Browser: a web-based browser for visualizing 3D genome organization and long-range chromatin interactions

• Downloaded 2,908 times
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  • Site-wide: 4,000
  • In bioinformatics: 430
• Year to date:
  • Site-wide: 66,605
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  • Site-wide: 66,605

Histone H3 Lysine 4 methyltransferases MLL3 and MLL4 Modulate Long-range Chromatin Interactions at Enhancers

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  • Site-wide: 4,899
  • In genomics: 571
• Year to date:
  • Site-wide: 42,848
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  • Site-wide: 42,848

Using three-dimensional regulatory chromatin interactions from adult and fetal cortex to interpret genetic results for psychiatric disorders and cognitive traits

• Downloaded 2,154 times
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  • Site-wide: 6,210
  • In genetics: 307
• Year to date:
  • Site-wide: 7,741
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  • Site-wide: 7,741

HiCPlus: Resolution Enhancement of Hi-C interaction heatmap

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  • Site-wide: 6,303
  • In bioinformatics: 752
• Year to date:
  • Site-wide: 83,879
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  • Site-wide: 83,879

3D Epigenomic Characterization Reveals Insights Into Gene Regulation and Lineage Specification During Corticogenesis

• Downloaded 1,546 times
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  • Site-wide: 10,189
  • In genomics: 1,131
• Year to date:
  • Site-wide: 25,495
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  • Site-wide: 25,495

CTCF Mediates Dosage and Sequence-context-dependent Transcriptional Insulation through Formation of Local Chromatin Domains

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  • Site-wide: 10,466
  • In molecular biology: 289
• Year to date:
  • Site-wide: 10,273
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  • Site-wide: 10,273

CTCF Promotes Long-range Enhancer-promoter Interactions and Lineage-specific Gene Expression in Mammalian Cells

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  • Site-wide: 10,527
  • In genomics: 1,170
• Year to date:
  • Site-wide: 10,331
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  • Site-wide: 10,331

Common DNA sequence variation influences 3-dimensional conformation of the human genome

• Downloaded 1,477 times
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  • Site-wide: 10,889
  • In genomics: 1,207
• Year to date:
  • Site-wide: 108,830
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  • Site-wide: 108,830

Removing unwanted variation between samples in Hi-C experiments

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  • Site-wide: 13,419
  • In genomics: 1,460
• Year to date:
  • Site-wide: 9,846
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  • Site-wide: 9,846

Reliable sensory processing in mouse visual cortex through inhibitory interactions between Somatostatin and Parvalbumin interneurons

• Downloaded 1,267 times
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  • Site-wide: 13,718
  • In neuroscience: 1,635
• Year to date:
  • Site-wide: 60,632
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  • Site-wide: 60,632

Robust Hi-C chromatin loop maps in human neurogenesis and brain tissues at high-resolution

• Downloaded 1,232 times
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  • Site-wide: 14,323
  • In genomics: 1,521
• Year to date:
  • Site-wide: 10,229
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  • Site-wide: 10,229

MAPS: model-based analysis of long-range chromatin interactions from PLAC-seq and HiChIP experiments

• Downloaded 1,143 times
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  • Site-wide: 16,047
  • In bioinformatics: 1,971
• Year to date:
  • Site-wide: 81,670
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  • Site-wide: 81,670

HUGIn: Hi-C Unifying Genomic Interrogator

• Downloaded 730 times
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  • Site-wide: 30,553
  • In genetics: 1,520
• Year to date:
  • Site-wide: 84,137
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  • Site-wide: 84,137

In V4, pair-wise synchrony and correlations depend on the structure of the population code

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  • Site-wide: 33,141
  • In neuroscience: 4,617
• Year to date:
  • Site-wide: 63,052
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  • Site-wide: 63,052

BAMM-SC: A Bayesian mixture model for clustering droplet-based single cell transcriptomic data from population studies

• Downloaded 640 times
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  • Site-wide: 36,472
  • In bioinformatics: 4,056
• Year to date:
  • Site-wide: 47,343
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  • Site-wide: 47,343

TWO-SIGMA: a novel TWO-component SInGle cell Model-based Association method for single-cell RNA-seq data

• Downloaded 554 times
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  • Site-wide: 43,749
  • In genomics: 3,582
• Year to date:
  • Site-wide: 47,791
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  • Site-wide: 47,791

Integrative analyses of multi-tissue Hi-C and eQTL data demonstrate close spatial proximity between eQTLs and their target genes

• Downloaded 537 times
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  • Site-wide: 45,447
  • In systems biology: 1,061
• Year to date:
  • Site-wide: 81,884
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  • Site-wide: 81,884

FIREcaller: Detecting Frequently Interacting Regions from Hi-C Data

• Downloaded 515 times
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  • Site-wide: 47,753
  • In bioinformatics: 5,008
• Year to date:
  • Site-wide: 47,759
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  • Site-wide: 47,759

Label-free characterization of visual cortical areas in awake mice via three-photon microscopy reveals correlations between functional maps and structural substrates

• Downloaded 486 times
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  • Site-wide: 51,158
  • In neuroscience: 7,617
• Year to date:
  • Site-wide: 102,618
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  • Site-wide: 102,618

SnapHiC: a computational pipeline to map chromatin contacts from single cell Hi-C data

• Downloaded 426 times
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  • Site-wide: 58,918
  • In bioinformatics: 5,882
• Year to date:
  • Site-wide: 5,356
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  • Site-wide: 5,356

Transcriptional Network Orchestrating Regional Patterning of Cortical Progenitors

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  • Site-wide: 69,262
  • In neuroscience: 10,624
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  • Site-wide: 24,752
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  • Site-wide: 24,752

Choice can be predicted from populations of bursting neurons in superficial layers of monkey V1

• Downloaded 324 times
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  • Site-wide: 75,572
  • In neuroscience: 11,639
• Year to date:
  • Site-wide: 87,715
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  • Site-wide: 87,715

Reading-out task variables as a low-dimensional reconstruction of neural spike trains in single trials

• Downloaded 321 times
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  • Site-wide: 76,002
  • In neuroscience: 11,736
• Year to date:
  • Site-wide: 120,256
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  • Site-wide: 120,256

THUNDER: A reference-free deconvolution method to infer cell type proportions from bulk Hi-C data

• Downloaded 219 times
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  • Site-wide: 97,353
  • In bioinformatics: 8,426
• Year to date:
  • Site-wide: 31,628
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  • Site-wide: 31,628

HiC-ACT: Improved Detection of Chromatin Interactions from Hi-C Data via Aggregated Cauchy Test

• Downloaded 188 times
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  • Site-wide: 104,114
  • In bioinformatics: 8,820
• Year to date:
  • Site-wide: 33,368
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  • Site-wide: 33,368

Sexually dimorphic roles for the type 2 diabetes-associated C2cd4b gene in murine glucose homeostasis

• Downloaded 160 times
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  • Site-wide: 109,617
  • In genetics: 4,850
• Year to date:
  • Site-wide: 68,888
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  • Site-wide: 68,888

Chromatin 3D interaction analysis of the STARD10 locus unveils FCHSD2 as a new regulator of insulin secretion

• Downloaded 134 times
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  • Site-wide: 114,691
  • In cell biology: 5,310
• Year to date:
  • Site-wide: 46,801
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  • Site-wide: 46,801

TWO-SIGMA-G: A New Competitive Gene Set Testing Framework for scRNA-seq Data Accounting for Inter-Gene and Cell-Cell Correlation

• Downloaded 131 times
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  • Site-wide: 115,138
  • In genomics: 6,404
• Year to date:
  • Site-wide: 7,530
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  • Site-wide: 7,530

MUNIn (Multiple cell-type UNifying long-range chromatin Interaction detector): a statistical framework for identifying long-range chromatin interactions from multiple cell types

• Downloaded 126 times
• Download rankings, all-time:
  • Site-wide: 116,021
  • In genetics: 5,050
• Year to date:
  • Site-wide: 76,622
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  • Site-wide: 76,622

HPRep: Quantifying reproducibility in HiChIP and PLAC-seq datasets

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  • Site-wide: 122,992
  • In genomics: 6,623
• Year to date:
  • Site-wide: 57,595
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  • Site-wide: 57,595