Author: Ming Hu

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Preprints

Caution on Kidney Dysfunctions of 2019-nCoV Patients

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  • Site-wide: 680
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• Year to date:
  • Site-wide: 2,568
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  • Site-wide: 3,251

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

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  • Site-wide: 894
  • In genetics: 26
• Year to date:
  • Site-wide: 34,573
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  • Site-wide: 45,224

The 3D Genome Browser: a web-based browser for visualizing 3D genome organization and long-range chromatin interactions

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  • Site-wide: 4,388
  • In bioinformatics: 451
• Year to date:
  • Site-wide: 70,632
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  • Site-wide: 127,157

Histone H3 Lysine 4 methyltransferases MLL3 and MLL4 Modulate Long-range Chromatin Interactions at Enhancers

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  • Site-wide: 5,356
  • In genomics: 592
• Year to date:
  • Site-wide: 60,642
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  • Site-wide: 80,603

Using three-dimensional regulatory chromatin interactions from adult and fetal cortex to interpret genetic results for psychiatric disorders and cognitive traits

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  • Site-wide: 6,298
  • In genetics: 297
• Year to date:
  • Site-wide: 9,563
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  • Site-wide: 14,051

HiCPlus: Resolution Enhancement of Hi-C interaction heatmap

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  • Site-wide: 6,962
  • In bioinformatics: 820
• Year to date:
  • Site-wide: 113,086
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  • Site-wide: 110,725

3D Epigenomic Characterization Reveals Insights Into Gene Regulation and Lineage Specification During Corticogenesis

• Downloaded 1,755 times
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  • Site-wide: 9,369
  • In genomics: 1,013
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  • Site-wide: 10,254
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  • Site-wide: 6,648

CTCF Mediates Dosage and Sequence-context-dependent Transcriptional Insulation through Formation of Local Chromatin Domains

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  • Site-wide: 9,785
  • In molecular biology: 258
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  • Site-wide: 8,694
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  • Site-wide: 8,210

CTCF Promotes Long-range Enhancer-promoter Interactions and Lineage-specific Gene Expression in Mammalian Cells

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  • Site-wide: 10,246
  • In genomics: 1,104
• Year to date:
  • Site-wide: 11,374
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  • Site-wide: 14,501

Common DNA sequence variation influences 3-dimensional conformation of the human genome

• Downloaded 1,490 times
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  • Site-wide: 11,883
  • In genomics: 1,285
• Year to date:
  • Site-wide: 112,257
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  • Site-wide: 71,903

Removing unwanted variation between samples in Hi-C experiments

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  • Site-wide: 13,681
  • In genomics: 1,448
• Year to date:
  • Site-wide: 16,327
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  • Site-wide: 33,410

Robust Hi-C chromatin loop maps in human neurogenesis and brain tissues at high-resolution

• Downloaded 1,331 times
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  • Site-wide: 14,136
  • In genomics: 1,485
• Year to date:
  • Site-wide: 14,146
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  • Site-wide: 23,217

Reliable sensory processing in mouse visual cortex through inhibitory interactions between Somatostatin and Parvalbumin interneurons

• Downloaded 1,311 times
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  • Site-wide: 14,444
  • In neuroscience: 1,694
• Year to date:
  • Site-wide: 50,704
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  • Site-wide: 38,468

MAPS: model-based analysis of long-range chromatin interactions from PLAC-seq and HiChIP experiments

• Downloaded 1,155 times
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  • Site-wide: 17,483
  • In bioinformatics: 2,093
• Year to date:
  • Site-wide: 100,150
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  • Site-wide: 62,832

HUGIn: Hi-C Unifying Genomic Interrogator

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  • Site-wide: 33,459
  • In genetics: 1,600
• Year to date:
  • Site-wide: 122,462
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  • Site-wide: 124,282

In V4, pair-wise synchrony and correlations depend on the structure of the population code

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  • Site-wide: 35,525
  • In neuroscience: 4,914
• Year to date:
  • Site-wide: 86,378
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  • Site-wide: 109,241

BAMM-SC: A Bayesian mixture model for clustering droplet-based single cell transcriptomic data from population studies

• Downloaded 654 times
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  • Site-wide: 39,008
  • In bioinformatics: 4,256
• Year to date:
  • Site-wide: 74,564
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  • Site-wide: 134,886

TWO-SIGMA: a novel TWO-component SInGle cell Model-based Association method for single-cell RNA-seq data

• Downloaded 607 times
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  • Site-wide: 42,895
  • In genomics: 3,488
• Year to date:
  • Site-wide: 41,735
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  • Site-wide: 56,163

Integrative analyses of multi-tissue Hi-C and eQTL data demonstrate close spatial proximity between eQTLs and their target genes

• Downloaded 545 times
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  • Site-wide: 49,039
  • In systems biology: 1,121
• Year to date:
  • Site-wide: 109,738
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  • Site-wide: 127,078

FIREcaller: Detecting Frequently Interacting Regions from Hi-C Data

• Downloaded 532 times
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  • Site-wide: 50,386
  • In bioinformatics: 5,201
• Year to date:
  • Site-wide: 70,514
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  • Site-wide: 120,207

SnapHiC: a computational pipeline to map chromatin contacts from single cell Hi-C data

• Downloaded 530 times
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  • Site-wide: 50,544
  • In bioinformatics: 5,222
• Year to date:
  • Site-wide: 9,413
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  • Site-wide: 25,025

Label-free characterization of visual cortical areas in awake mice via three-photon microscopy reveals correlations between functional maps and structural substrates

• Downloaded 498 times
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  • Site-wide: 54,461
  • In neuroscience: 8,040
• Year to date:
  • Site-wide: 110,957
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  • Site-wide: 100,086

Transcriptional Network Orchestrating Regional Patterning of Cortical Progenitors

• Downloaded 408 times
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  • Site-wide: 67,108
  • In neuroscience: 10,139
• Year to date:
  • Site-wide: 34,174
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  • Site-wide: 127,908

Choice can be predicted from populations of bursting neurons in superficial layers of monkey V1

• Downloaded 399 times
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  • Site-wide: 68,620
  • In neuroscience: 10,339
• Year to date:
  • Site-wide: 37,788
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  • Site-wide: 58,719

Parallel Characterization of cis-Regulatory Elements for Multiple Genes UsingCRISPRpath

• Downloaded 397 times
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  • Site-wide: 69,039
  • In genomics: 4,807
• Year to date:
  • Site-wide: 5,443
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  • Site-wide: 7,934

Reading-out task variables as a low-dimensional reconstruction of neural spike trains in single trials

• Downloaded 334 times
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  • Site-wide: 80,379
  • In neuroscience: 12,278
• Year to date:
  • Site-wide: 120,876
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  • Site-wide: 83,289

THUNDER: A reference-free deconvolution method to infer cell type proportions from bulk Hi-C data

• Downloaded 233 times
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  • Site-wide: 102,129
  • In bioinformatics: 8,704
• Year to date:
  • Site-wide: 60,868
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  • Site-wide: 61,976

HiC-ACT: Improved Detection of Chromatin Interactions from Hi-C Data via Aggregated Cauchy Test

• Downloaded 212 times
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  • Site-wide: 106,963
  • In bioinformatics: 9,007
• Year to date:
  • Site-wide: 53,576
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  • Site-wide: 75,996

TWO-SIGMA-G: A New Competitive Gene Set Testing Framework for scRNA-seq Data Accounting for Inter-Gene and Cell-Cell Correlation

• Downloaded 186 times
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  • Site-wide: 112,891
  • In genomics: 6,376
• Year to date:
  • Site-wide: 15,630
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  • Site-wide: 36,646

MUNIn (Multiple sample UNifying long-range chromatin Interaction detector): a statistical framework for identifying long-range chromatin interactions from multiple samples

• Downloaded 179 times
• Download rankings, all-time:
  • Site-wide: 114,344
  • In genetics: 4,934
• Year to date:
  • Site-wide: 48,083
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  • Site-wide: 14,444

Sexually dimorphic roles for the type 2 diabetes-associated C2cd4b gene in murine glucose homeostasis

• Downloaded 172 times
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  • Site-wide: 115,987
  • In genetics: 4,979
• Year to date:
  • Site-wide: 94,517
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  • Site-wide: 76,184

Super interactive promoters provide insight into cell type-specific regulatory networks in blood lineage cell types

• Downloaded 144 times
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  • Site-wide: 121,995
  • In genetics: 5,168
• Year to date:
  • Site-wide: 21,708
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  • Site-wide: 15,246

Chromatin 3D interaction analysis of the STARD10 locus unveils FCHSD2 as a new regulator of insulin secretion

• Downloaded 144 times
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  • Site-wide: 121,903
  • In cell biology: 5,629
• Year to date:
  • Site-wide: 80,567
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  • Site-wide: 85,652

HPRep: Quantifying reproducibility in HiChIP and PLAC-seq datasets

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  • Site-wide: 128,269
  • In genomics: 6,829
• Year to date:
  • Site-wide: 64,670
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  • Site-wide: 59,966