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Author: Peter K. Sorger

Rankings

  • All-time downloads: 24,942 (rank: 1,784 out of 362,938)
  • Categories:
    • bioinformatics: 3,535 (rank: 2,648 (tie) out of 31,380)
    • cancer biology: 11,785 (rank: 111 out of 24,690)
    • cell biology: 744 (rank: 6,935 (tie) out of 26,608)
    • immunology: 712 (rank: 5,216 (tie) out of 18,877)
    • neuroscience: 1,047 (rank: 14,374 (tie) out of 61,016)
    • pathology: 256 (rank: 2,196 (tie) out of 3,756)
    • pharmacology and toxicology: 906 (rank: 572 (tie) out of 4,790)
    • scientific communication and education: 627 (rank: 1,098 out of 3,026)
    • systems biology: 5,330 (rank: 451 out of 10,802)

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Preprints

Machine Learning Identifies Novel Candidates for Drug Repurposing in Alzheimer's Disease

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Multi-omics profiling establishes the polypharmacology of FDA Approved CDK4/6 inhibitors and the potential for differential clinical activity

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Highly multiplexed immunofluorescence imaging of human tissues and tumors using t-CyCIF and conventional optical microscopes

cancer biology more details view paper
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GeneWalk identifies relevant gene functions for a biological context using network representation learning

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Cheminformatics tools for analyzing and designing optimized small molecule libraries

systems biology more details view paper
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Receptor-Based Mechanism of Cell Memory and Relative Sensing in Mammalian Signaling Networks

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From word models to executable models of signaling networks using automated assembly

systems biology more details view paper
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Genome-encoded Cytoplasmic Double-Stranded RNAs, Found in C9ORF72 ALS-FTD Brain, Provoke Propagated Neuronal Death

neuroscience more details view paper
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A curative combination therapy for lymphomas achieves high fractional cell killing through low cross-resistance and drug additivity but not synergy

cancer biology more details view paper
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Opposing immune and genetic forces shape oncogenic programs in synovial sarcoma

cancer biology more details view paper
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    • In cancer biology: 306 out of 2,951
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Facetto: Combining Unsupervised and Supervised Learning for Hierarchical Phenotype Analysis in Multi-Channel Image Data

systems biology more details view paper
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A multi-center study on factors influencing the reproducibility of in vitro drug-response studies

cancer biology more details view paper
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    • In cancer biology: 349 out of 2,951
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Adaptation of human iPSC-derived cardiomyocytes to tyrosine kinase inhibitors reduces acute cardiotoxicity via metabolic reprogramming

pharmacology and toxicology more details view paper
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    • In pharmacology and toxicology: 71 out of 756
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Sporadic ERK pulses drive non-genetic resistance in drug-adapted BRAFV600E melanoma cells

cancer biology more details view paper
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    • In cancer biology: 396 out of 2,951
  • Year to date:
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Time resolved quantitative phosphoproteomics reveals distinct patterns of SHP2 dependence in EGFR signaling

cell biology more details view paper
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    • In cell biology: 717 out of 4,285
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Systemic immune response profiling with SYLARAS implicates a role for CD45R/B220+ CD8+ T cells in glioblastoma immunology

immunology more details view paper
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Comparing the efficacy of cancer therapies between subgroups in basket trials

cancer biology more details view paper
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FamPlex: a resource for entity recognition and relationship resolution of human protein families and complexes in biomedical text mining

bioinformatics more details view paper
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Inferring reaction network structure from single-cell, multiplex data, using toric systems theory

systems biology more details view paper
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Maintaining the provenance of microscopy metadata using OMERO.forms software

scientific communication and education more details view paper
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    • In scientific communication and education: 298 out of 582
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Interpretative guides for interacting with tissue atlas and digital pathology data using the Minerva browser

scientific communication and education more details view paper
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Channel Embedding for Informative Protein Identification from Highly Multiplexed Images

pathology more details view paper
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Combined inhibition of mTOR and PIKKs exploits replicative and checkpoint vulnerabilities to induce death of PI3K-activated triple-negative breast cancer cells

cancer biology more details view paper
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Assembling a phosphoproteomic knowledge base using ProtMapper to normalize phosphosite information from databases and text mining

bioinformatics more details view paper
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Exploring the understudied human kinome for research and therapeutic opportunities

systems biology more details view paper
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Biomarker-guided treatment strategies for ovarian cancer identified from a heterogeneous panel of patient-derived tumor xenografts

cancer biology more details view paper
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