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Author: Hao Chen

  • ORCiD: http://orcid.org/0000-0001-6697-0809
  • Most recently observed institution: Dept. of Pharmacology, Addiction Science and Toxicology, College of medicine, University of Tennessee Health Science Center, 71 S Manassas St., Memphis, TN

Rankings

  • All-time downloads: 201,299 (rank: 593 )
  • Categories:
    • animal behavior and cognition: 628 (rank: 2,878 (tie) )
    • biochemistry: 2,579 (rank: 2,059 (tie) )
    • bioengineering: 407 (rank: 13,041 (tie) )
    • bioinformatics: 22,576 (rank: 326 )
    • cancer biology: 1,435 (rank: 7,589 )
    • cardiovascular medicine: 488 (rank: 2,040 (tie) )
    • cell biology: 1,258 (rank: 9,245 (tie) )
    • developmental biology: 112,239 (rank: 5 (tie) )
    • epidemiology: 567 (rank: 20,231 (tie) )
    • evolutionary biology: 1,651 (rank: 4,777 (tie) )
    • genetics: 3,384 (rank: 6,680 )
    • genomics: 105 (rank: 57,794 (tie) )
    • immunology: 123 (rank: 45,244 (tie) )
    • infectious diseases: 19,151 (rank: 3,952 )
    • molecular biology: 2,606 (rank: 2,251 (tie) )
    • neuroscience: 2,125 (rank: 14,618 (tie) )
    • oncology: 2,461 (rank: 171 )
    • plant biology: 1,014 (rank: 5,582 (tie) )
    • public and global health: 14,754 (rank: 476 )
    • respiratory medicine: 2,438 (rank: 577 (tie) )
    • systems biology: 1,193 (rank: 4,720 (tie) )

Downloads per author, site-wide

Preprints

A conserved role of α2δ subunit of calcium channel in nicotine motivated behavior.

neuroscience more details view paper

No download data for this paper yet.

Reversing age: dual species measurement of epigenetic age with a single clock

developmental biology more details view paper
  • Downloaded 108,218 times
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    • Site-wide: 70
    • In developmental biology: 1
  • Year to date:
    • Site-wide: 797
  • Since beginning of last month:
    • Site-wide: 1,153

TBtools - an integrative toolkit developed for interactive analyses of big biological data

bioinformatics more details view paper
  • Downloaded 18,257 times
  • Download rankings, all-time:
    • Site-wide: 597
    • In bioinformatics: 17
  • Year to date:
    • Site-wide: 520
  • Since beginning of last month:
    • Site-wide: 747

Gut microbiota may underlie the predisposition of healthy individuals to COVID-19

public and global health more details view paper
  • Downloaded 14,511 times
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    • Site-wide: 794
    • In public and global health: 28
  • Year to date:
    • Site-wide: 5,792
  • Since beginning of last month:
    • Site-wide: 6,023

Proteomic and Metabolomic Characterization of COVID-19 Patient Sera

infectious diseases more details view paper
  • Downloaded 13,366 times
  • Download rankings, all-time:
    • Site-wide: 883
    • In infectious diseases: 290
  • Year to date:
    • Site-wide: 30,863
  • Since beginning of last month:
    • Site-wide: 33,683

Universal DNA methylation age across mammalian tissues

developmental biology more details view paper
  • Downloaded 5,557 times
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    • Site-wide: 2,751
    • In developmental biology: 20
  • Year to date:
    • Site-wide: 1,903
  • Since beginning of last month:
    • Site-wide: 1,946

Multi-organ Proteomic Landscape of COVID-19 Autopsies

infectious diseases more details view paper
  • Downloaded 2,296 times
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    • Site-wide: 9,663
    • In infectious diseases: 1,495
  • Year to date:
    • Site-wide: 59,444
  • Since beginning of last month:
    • Site-wide: 41,990

Protein Classifier for Thyroid Nodules Learned from Rapidly Acquired Proteotypes

oncology more details view paper
  • Downloaded 2,177 times
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    • Site-wide: 10,430
    • In oncology: 12
  • Year to date:
    • Site-wide: 14,217
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    • Site-wide: 10,306

Fast functional annotation of metagenomic shotgun data by DNA alignment to a microbial gene catalog

bioinformatics more details view paper
  • Downloaded 2,024 times
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    • Site-wide: 11,685
    • In bioinformatics: 1,197
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    • Site-wide: 83,190
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    • Site-wide: 77,301

Epigenetic predictors of maximum lifespan and other life history traits in mammals

evolutionary biology more details view paper
  • Downloaded 1,996 times
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    • Site-wide: 11,929
    • In evolutionary biology: 431
  • Year to date:
    • Site-wide: 5,492
  • Since beginning of last month:
    • Site-wide: 1,944

Proteomics Uncovers Immunosuppression in COVID-19 Patients with Long Disease Course

respiratory medicine more details view paper
  • Downloaded 1,527 times
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    • Site-wide: 17,838
    • In respiratory medicine: 60
  • Year to date:
    • Site-wide: 52,823
  • Since beginning of last month:
    • Site-wide: 43,302

METTL5, an 18S rRNA-specific m6A methyltransferase, modulates expression of stress response genes

biochemistry more details view paper
  • Downloaded 1,498 times
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    • Site-wide: 18,322
    • In biochemistry: 405
  • Year to date:
    • Site-wide: 29,330
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    • Site-wide: 28,418

PCIF1 catalyzes m6Am mRNA methylation to regulate gene expression

molecular biology more details view paper
  • Downloaded 1,483 times
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    • Site-wide: 18,609
    • In molecular biology: 459
  • Year to date:
    • Site-wide: 122,332
  • Since beginning of last month:
    • Site-wide: 125,655

Evaluation of transplacental transfer of mRNA vaccine products and functional antibodies during pregnancy and early infancy

infectious diseases more details view paper
  • Downloaded 1,472 times
  • Download rankings, all-time:
    • Site-wide: 18,834
    • In infectious diseases: 2,414
  • Year to date:
    • Site-wide: 3,175
  • Since beginning of last month:
    • Site-wide: 11,301

Integrative pipeline for profiling DNA copy number and inferring tumor phylogeny

bioinformatics more details view paper
  • Downloaded 1,255 times
  • Download rankings, all-time:
    • Site-wide: 24,176
    • In bioinformatics: 2,465
  • Year to date:
    • Site-wide: 160,134
  • Since beginning of last month:
    • Site-wide: 153,044

Genome wide association study in 3,173 outbred rats identifies multiple loci for body weight, adiposity, and fasting glucose

genetics more details view paper
  • Downloaded 1,084 times
  • Download rankings, all-time:
    • Site-wide: 30,249
    • In genetics: 1,233
  • Year to date:
    • Site-wide: 66,926
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    • Site-wide: 92,725

Identification of piRNA binding sites reveals the Argonaute regulatory landscape of the C. elegans germline

genetics more details view paper
  • Downloaded 1,070 times
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    • Site-wide: 30,833
    • In genetics: 1,215
  • Year to date:
    • Site-wide: 175,724
  • Since beginning of last month:
    • Site-wide: 186,998

Convergent network effects along the axis of gene expression during prostate cancer progression

systems biology more details view paper
  • Downloaded 1,032 times
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    • Site-wide: 32,523
    • In systems biology: 603
  • Year to date:
    • Site-wide: 82,219
  • Since beginning of last month:
    • Site-wide: 98,565

CRISPR/Cas9 screens Reveal Dasatinib Targets of Inhibiting T cell Activation and Proliferation

cancer biology more details view paper
  • Downloaded 1,025 times
  • Download rankings, all-time:
    • Site-wide: 32,880
    • In cancer biology: 806
  • Year to date:
    • Site-wide: 59,944
  • Since beginning of last month:
    • Site-wide: 77,042

SARS-CoV-2 entry related genes are comparably expressed in children's lung as adults

respiratory medicine more details view paper
  • Downloaded 993 times
  • Download rankings, all-time:
    • Site-wide: 34,455
    • In respiratory medicine: 84
  • Year to date:
    • Site-wide: 89,684
  • Since beginning of last month:
    • Site-wide: 146,775

Eleven Routine Clinical Features Predict COVID-19 Severity

infectious diseases more details view paper
  • Downloaded 956 times
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    • Site-wide: 36,420
    • In infectious diseases: 2,954
  • Year to date:
    • Site-wide: 94,530
  • Since beginning of last month:
    • Site-wide: 82,659

A Universal Nonparametric Event Detection Framework for Neuropixels Data

neuroscience more details view paper
  • Downloaded 851 times
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    • Site-wide: 43,272
    • In neuroscience: 5,624
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    • Site-wide: 93,332
  • Since beginning of last month:
    • Site-wide: 92,494

The landscape of mouse epididymal cells defined by the single-cell RNA-Seq

cell biology more details view paper
  • Downloaded 847 times
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    • Site-wide: 43,623
    • In cell biology: 1,606
  • Year to date:
    • Site-wide: 117,474
  • Since beginning of last month:
    • Site-wide: 88,979

GeneCup: mine PubMed for gene relationships using custom ontology and deep learning

bioinformatics more details view paper
  • Downloaded 832 times
  • Download rankings, all-time:
    • Site-wide: 44,781
    • In bioinformatics: 5,280
  • Year to date:
    • Site-wide: 24,464
  • Since beginning of last month:
    • Site-wide: 8,923

3D chromatin organization changes modulate adipogenesis and osteogenesis

genetics more details view paper
  • Downloaded 657 times
  • Download rankings, all-time:
    • Site-wide: 62,641
    • In genetics: 2,520
  • Year to date:
    • Site-wide: 78,953
  • Since beginning of last month:
    • Site-wide: 89,707

The human mitochondrial 12S rRNA m4C methyltransferase METTL15 is required for proper mitochondrial function

molecular biology more details view paper
  • Downloaded 601 times
  • Download rankings, all-time:
    • Site-wide: 70,362
    • In molecular biology: 1,881
  • Year to date:
    • Site-wide: 123,968
  • Since beginning of last month:
    • Site-wide: 162,305

Causally Associations of Blood Lipids Levels with COVID-19 Risk: Mendelian Randomization Study

epidemiology more details view paper
  • Downloaded 598 times
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    • Site-wide: 70,820
    • In epidemiology: 3,123
  • Year to date:
    • Site-wide: 104,485
  • Since beginning of last month:
    • Site-wide: 61,937

Analytical and Clinical Validation of an Amplicon-based Next Generation Sequencing Assay for Ultrasensitive Detection of Circulating Tumor DNA

oncology more details view paper
  • Downloaded 592 times
  • Download rankings, all-time:
    • Site-wide: 71,680
    • In oncology: 164
  • Year to date:
    • Site-wide: 20,423
  • Since beginning of last month:
    • Site-wide: 30,490

Gallic Acid Disrupts Aβ1-42 Aggregation and Rescues Cognitive Decline of APP/PS1 Transgenic Mouse

neuroscience more details view paper
  • Downloaded 590 times
  • Download rankings, all-time:
    • Site-wide: 72,013
    • In neuroscience: 9,646
  • Year to date:
    • Site-wide: 154,841
  • Since beginning of last month:
    • Site-wide: 185,658

Chansu Injection Improves the Respiratory Function of Severe COVID-19 Patients

infectious diseases more details view paper
  • Downloaded 563 times
  • Download rankings, all-time:
    • Site-wide: 76,264
    • In infectious diseases: 4,358
  • Year to date:
    • Site-wide: 76,336
  • Since beginning of last month:
    • Site-wide: 108,034

An allele-specific functional SNP associated with two autoimmune diseases modulates IRF5 expression by long-range chromatin loop formation

genetics more details view paper
  • Downloaded 561 times
  • Download rankings, all-time:
    • Site-wide: 76,588
    • In genetics: 2,983
  • Year to date:
    • Site-wide: 144,892
  • Since beginning of last month:
    • Site-wide: 111,617

Computational approaches towards reducing contamination in single-cell RNA-seq data

bioinformatics more details view paper
  • Downloaded 561 times
  • Download rankings, all-time:
    • Site-wide: 76,628
    • In bioinformatics: 6,968
  • Year to date:
    • Site-wide: 89,630
  • Since beginning of last month:
    • Site-wide: 115,263

LncRNA and predictive model for improving the diagnosis of clinically diagnosed pulmonary tuberculosis

infectious diseases more details view paper
  • Downloaded 560 times
  • Download rankings, all-time:
    • Site-wide: 76,761
    • In infectious diseases: 4,240
  • Year to date:
    • Site-wide: 99,831
  • Since beginning of last month:
    • Site-wide: 115,122

A family of C. elegans VASA homologs control Argonaute pathway specificity and promote transgenerational silencing

molecular biology more details view paper
  • Downloaded 536 times
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    • Site-wide: 80,926
    • In molecular biology: 2,992
  • Year to date:
    • Site-wide: 4,567
  • Since beginning of last month:
    • Site-wide: 25,606

The repertoire of testicular extracellular vesicles cargoes and their involvement in inter-compartmental communication required for spermatogenesis

cell biology more details view paper
  • Downloaded 532 times
  • Download rankings, all-time:
    • Site-wide: 81,654
    • In cell biology: 4,240
  • Year to date:
    • Site-wide: 35,884
  • Since beginning of last month:
    • Site-wide: 21,707

Diagnostics and prognostic potential of current biomarkers in heart failure with preserved ejection fraction: a systematic review and meta-analysis

cardiovascular medicine more details view paper
  • Downloaded 529 times
  • Download rankings, all-time:
    • Site-wide: 82,232
    • In cardiovascular medicine: 174
  • Year to date:
    • Site-wide: 70,377
  • Since beginning of last month:
    • Site-wide: 78,515

COVID-19 Quarantine Reveals Grade-specific Behavioral Modification of Myopia: One-Million Chinese Schoolchildren Study

public and global health more details view paper
  • Downloaded 503 times
  • Download rankings, all-time:
    • Site-wide: 87,238
    • In public and global health: 1,246
  • Year to date:
    • Site-wide: 93,999
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    • Site-wide: 122,826

Modeling circRNAs expression pattern with integrated sequence and epigenetic features identifies H3K79me2 as regulators for circRNAs expression

bioinformatics more details view paper
  • Downloaded 499 times
  • Download rankings, all-time:
    • Site-wide: 88,178
    • In bioinformatics: 7,444
  • Year to date:
    • Site-wide: 139,567
  • Since beginning of last month:
    • Site-wide: 126,184

The Tung Tree (Vernicia Fordii) Genome Provides A Resource for Understanding Genome Evolution and Oil Improvement

bioinformatics more details view paper
  • Downloaded 481 times
  • Download rankings, all-time:
    • Site-wide: 91,776
    • In bioinformatics: 7,639
  • Year to date:
    • Site-wide: 167,172
  • Since beginning of last month:
    • Site-wide: 114,859

Mechanism of multimodal substrate translocation in P-glycoprotein

biophysics more details view paper
  • Downloaded 477 times
  • Download rankings, all-time:
    • Site-wide: 92,787
    • In biophysics: None
  • Year to date:
    • Site-wide: 5,453
  • Since beginning of last month:
    • Site-wide: 1,650

A diagnostic decision-making protocol combines a new-generation of serological assay and PCR to fully resolve ambiguity in COVID-19 diagnosis

infectious diseases more details view paper
  • Downloaded 472 times
  • Download rankings, all-time:
    • Site-wide: 93,642
    • In infectious diseases: 4,706
  • Year to date:
    • Site-wide: 116,029
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    • Site-wide: 127,363

SAI: Fast and automated quantification of stomatal parameters on microscope images

plant biology more details view paper
  • Downloaded 471 times
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    • Site-wide: 94,059
    • In plant biology: 4,535
  • Year to date:
    • Site-wide: 5,566
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    • Site-wide: 7,061

Glucocorticoid Receptor-Regulated Enhancers Play a Central Role in the Gene Regulatory Networks Underlying Drug Addiction

neuroscience more details view paper
  • Downloaded 467 times
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    • Site-wide: 94,746
    • In neuroscience: 17,794
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    • Site-wide: 5,625
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    • Site-wide: 25,434

Hypoxic Training Increases the Concentration of Serum Irisin and Reduces Weight in Diet-induced Obese Rats

biochemistry more details view paper
  • Downloaded 456 times
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    • Site-wide: 97,288
    • In biochemistry: 2,591
  • Year to date:
    • Site-wide: 138,285
  • Since beginning of last month:
    • Site-wide: 166,495

Pyruvate carboxylase supports the pulmonary tropism of metastatic breast cancer

cancer biology more details view paper
  • Downloaded 454 times
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    • Site-wide: 97,848
    • In cancer biology: 2,634
  • Year to date:
    • Site-wide: 189,980
  • Since beginning of last month:
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Effects of planting density on the growth and photosynthetic characteristics of Alternanthera philoxeroides under different nutrient conditions

plant biology more details view paper
  • Downloaded 449 times
  • Download rankings, all-time:
    • Site-wide: 98,959
    • In plant biology: 2,584
  • Year to date:
    • Site-wide: 93,115
  • Since beginning of last month:
    • Site-wide: 66,003

Differential responses of transplanted stem cells to the diseased environment unveiled by a single molecular NIR II cell tracker

bioengineering more details view paper
  • Downloaded 431 times
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    • Site-wide: 103,020
    • In bioengineering: 1,916
  • Year to date:
    • Site-wide: 124,170
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    • Site-wide: 90,042

Multiple modulation synthesis with high spatial resolution for noninvasive deep neurostimulation

neuroscience more details view paper
  • Downloaded 427 times
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    • Site-wide: 104,118
    • In neuroscience: 14,170
  • Year to date:
    • Site-wide: 159,683
  • Since beginning of last month:
    • Site-wide: 171,281

Sequencing uracil in DNA at single-nucleotide resolution

biochemistry more details view paper
  • Downloaded 424 times
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    • Site-wide: 104,689
    • In biochemistry: 3,185
  • Year to date:
    • Site-wide: 39,617
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    • Site-wide: 33,801

Social behavior and anxiety contribute to nicotine self-administration in adolescent outbred rats

animal behavior and cognition more details view paper
  • Downloaded 414 times
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    • Site-wide: 107,084
    • In animal behavior and cognition: 1,045
  • Year to date:
    • Site-wide: 189,535
  • Since beginning of last month:
    • Site-wide: 190,232

CG14906 (mettl4) mediates m6A methylation of U2 snRNA in Drosophila

biochemistry more details view paper
  • Downloaded 394 times
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    • Site-wide: 112,096
    • In biochemistry: 3,041
  • Year to date:
    • Site-wide: 178,664
  • Since beginning of last month:
    • Site-wide: 176,180

Whole genome sequencing of nearly isogeneic WMI and WLI inbred rats identifies genes potentially involved in depression

bioinformatics more details view paper
  • Downloaded 388 times
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    • Site-wide: 113,591
    • In bioinformatics: 9,665
  • Year to date:
    • Site-wide: 66,047
  • Since beginning of last month:
    • Site-wide: 40,158

Retrograde induction of phyB orchestrates ethylene-auxin hierarchy to regulate growth

plant biology more details view paper
  • Downloaded 292 times
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    • Site-wide: 141,093
    • In plant biology: 3,702
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    • Site-wide: 150,278

A comprehensive mass spectral library for human thyroid tissues

systems biology more details view paper
  • Downloaded 243 times
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    • Site-wide: 155,527
    • In systems biology: 3,170
  • Year to date:
    • Site-wide: 72,691
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    • Site-wide: 69,020

TailTimer: an open-source device for automating the rodent tail immersion assay

animal behavior and cognition more details view paper
  • Downloaded 242 times
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    • Site-wide: 155,751
    • In animal behavior and cognition: 1,839
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    • Site-wide: 104,802
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    • Site-wide: 132,816

ORA47 is a transcriptional regulator of a general stress response hub

plant biology more details view paper
  • Downloaded 204 times
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    • Site-wide: 166,152
    • In plant biology: 4,466
  • Year to date:
    • Site-wide: 47,035
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    • Site-wide: 148,952

LncRNA and predictive model to improve the diagnosis of clinically diagnosed pulmonary tuberculosis

molecular biology more details view paper
  • Downloaded 195 times
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    • Site-wide: 168,247
    • In molecular biology: 4,744
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    • Site-wide: 162,460
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    • Site-wide: 117,238

Identification of the Novel Pyroptosis-Related Gene Signature in Patients with Esophageal Adenocarcinoma

bioinformatics more details view paper
  • Downloaded 190 times
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    • Site-wide: 169,516
    • In bioinformatics: 12,118
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    • Site-wide: 129,005

Polygenic Transcriptome Risk Scores Can Translate Genetic Results Between Species

genomics more details view paper
  • Downloaded 161 times
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  • Year to date:
    • Site-wide: 27,025
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    • Site-wide: 4,158

Genome-wide association study of open fieldbehavior in outbred heterogeneous stock ratsidentifies multiple loci implicated inpsychiatric disorders

genetics more details view paper
  • Downloaded 160 times
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    • Site-wide: 176,305
    • In genetics: 6,298
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    • Site-wide: 79,615

Hypoxia-mediated suppression of pyruvate carboxylase drives tumor microenvironment immunosuppression

cancer biology more details view paper
  • Downloaded 157 times
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    • Site-wide: 177,084
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Opiate responses are controlled by interactions of Oprm1 and Fgf12 loci in the murine BXD family: Correspondence to human GWAS findings

genetics more details view paper
  • Downloaded 154 times
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    • Site-wide: 177,542
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    • Site-wide: 28,643
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Previously unrecognized non-reproducible antibody-antigen interactions and their implications for diagnosis of viral infections including COVID-19

immunology more details view paper
  • Downloaded 144 times
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    • Site-wide: 179,507
    • In immunology: 5,323
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    • Site-wide: 159,358

The regulatory landscape of multiple brain regions in outbred heterogeneous stock rats

genetics more details view paper
  • Downloaded 138 times
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    • Site-wide: 180,471
    • In genetics: None
  • Year to date:
    • Site-wide: 33,072
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    • Site-wide: 48,674

SVJAM: Joint Analysis of Structural Variants Using Linked Read Sequencing Data

genomics more details view paper
  • Downloaded 133 times
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    • Site-wide: 181,444
    • In genomics: 8,285
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    • Site-wide: 96,124
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    • Site-wide: 104,153

PeerPub: A device for concurrent operant oral self-administration by multiple rats

animal behavior and cognition more details view paper
  • Downloaded 107 times
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    • Site-wide: 185,138
    • In animal behavior and cognition: None
  • Year to date:
    • Site-wide: 44,321
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    • Site-wide: 60,863

Single-cell perspectives on the function and development of deep-sea mussel bacteriocytes

molecular biology more details view paper
  • Downloaded 99 times
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    • Site-wide: 186,191
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  • Year to date:
    • Site-wide: 48,603
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    • Site-wide: 9,545

Private and sub-family specific mutations of founder haplotypes in the BXD family reveal phenotypic consequences relevant to health and disease

genomics more details view paper
  • Downloaded 83 times
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    • Site-wide: 187,913
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  • Year to date:
    • Site-wide: 57,987
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    • Site-wide: 31,784

Inflammatory Bowel Disease and Neurodegenerative Disorders: Integrated Evidence from Mendelian Randomization, Shared Genetic Architecture and Transcriptomics

gastroenterology more details view paper
  • Downloaded 72 times
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    • Site-wide: 188,881
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    • Site-wide: 66,575
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    • Site-wide: 16,182

FBXO11 deficiency in mice impairs lung development and aggravates cigarette smoke-induced airway fibrosis

cell biology more details view paper
  • Downloaded 47 times
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    • Site-wide: 190,434
    • In cell biology: None
  • Year to date:
    • Site-wide: 93,421
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Investigating Causal Relationships between Inflammatory Bowel Disease and Autism Spectrum Disorder: A Bidirectional Two-sample Mendelian Randomization Study

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