Author: Karsten Suhre

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Preprints

Consequences Of Natural Perturbations In The Human Plasma Proteome

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Connecting genetic risk to disease endpoints through the human blood plasma proteome

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  • Site-wide: 12,080
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  • Site-wide: 156,623
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Genome-wide Association Study Of Plasma Proteins Identifies Putatively Causal Genes, Proteins, And Pathways For Cardiovascular Disease

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Characterization of missing values in untargeted MS-based metabolomics data and evaluation of missing data handling strategies

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  • Site-wide: 25,258
  • In systems biology: 475
• Year to date:
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Mendelian randomisation identifies alternative splicing of the FAS death receptor as a mediator of severe COVID-19

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  • In infectious diseases: 2,782
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ProGeM: A framework for the prioritisation of candidate causal genes at molecular quantitative trait loci

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  • In bioinformatics: 3,971
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Accelerated lipid catabolism and autophagy are cancer survival mechanisms under inhibited glutaminolysis

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  • In cancer biology: 1,030
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Epigenetic scores for the circulating proteome as tools for disease prediction

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  • Site-wide: 9,750
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Genus-wide sequencing supports a two-locus model for sex-determination in Phoenix

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Variational autoencoders learn universal latent representations of metabolomics data

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  • In bioinformatics: 4,242
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Network-based metabolite ratios for an improved functional characterization of genome-wide association study results

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  • In genetics: 1,983
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  • Site-wide: 126,958
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  • Site-wide: 115,903

MoDentify: a tool for phenotype-driven module identification in multilevel metabolomics networks

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  • Site-wide: 53,441
  • In systems biology: 1,140
• Year to date:
  • Site-wide: 154,571
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  • Site-wide: 150,902

Defining the genetic control of human blood plasma N-glycome using genome-wide association study

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  • Site-wide: 53,562
  • In genetics: 2,285
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  • Site-wide: 141,350

Unraveling the functional role of the orphan solute carrier, SLC22A24 in the transport of steroid conjugates through metabolomic and genome-wide association studies

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  • In pharmacology and toxicology: 371
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Qatar Genome: Insights on Genomics from the Middle East

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  • In genetic and genomic medicine: 337
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A strategy to incorporate prior knowledge into correlation network cutoff selection

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  • Site-wide: 78,717
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  • Site-wide: 143,161

Elucidating the genetic risk of obesity through the human blood plasma proteome

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  • Site-wide: 81,654
  • In endocrinology: 67
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Deep sequencing of DNA from urine of kidney allograft recipients to estimate the donor-specific DNA fraction

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  • Site-wide: 85,251
  • In transplantation: 36
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Genome-wide scan identifies novel genetic loci regulating salivary metabolite levels

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  • In genetics: 3,599
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An Integrated Molecular Atlas of Alzheimer's Disease

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  • Site-wide: 87,972
  • In neurology: 285
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  • Site-wide: 20,934
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Characterization of bulk phosphatidylcholine compositions in human plasma using side-chain resolving lipidomics

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  • Site-wide: 99,065
  • In epidemiology: 4,229
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PopPAnTe: population and pedigree association testing for quantitative data

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  • Site-wide: 111,802
  • In bioinformatics: 9,296
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Twelve-year changes in protein profiles in patients with and without gastric bypass surgery

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  • Site-wide: 114,750
  • In genetic and genomic medicine: 646
• Year to date:
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Deletion of beta-fructofuranosidase (invertase) genes is associated with sucrose content in Date Palm fruit

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  • Site-wide: 118,448
  • In plant biology: 3,243
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Metabolic dysregulations of cancer cells with metastatic potential

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  • Site-wide: 132,347
  • In cancer biology: 4,050
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  • Site-wide: 46,407
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  • Site-wide: 61,673

Integrative Metabolomic and Proteomic Signatures Define Clinical Outcomes in Severe COVID-19

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  • Site-wide: 133,864
  • In infectious diseases: 5,644
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  • Site-wide: 100,661

Multi-Omic Analyses Characterize the Ceramide/Sphingomyelin Pathway as a Therapeutic Target in Alzheimer's Disease

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  • Site-wide: 143,855
  • In neurology: 767
• Year to date:
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Systems Biology Analysis of Human Genomes Points to Key Pathways Conferring Spina Bifida Risk

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  • Site-wide: 154,769
  • In genomics: 7,749
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