Author: Rong Zhang

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Preprints

Stability of the COVID-19 virus under wet, dry and acidic conditions

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  • Site-wide: 1,943
  • In infectious diseases: 553
• Year to date:
  • Site-wide: 5,716
• Since beginning of last month:
  • Site-wide: 12,026

Fully human single-domain antibodies against SARS-CoV-2

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  • Site-wide: 2,705
  • In microbiology: 208
• Year to date:
  • Site-wide: 21,158
• Since beginning of last month:
  • Site-wide: 38,793

Functional and Genetic Analysis of Viral Receptor ACE2 Orthologs Reveals a Broad Potential Host Range of SARS-CoV-2

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  • Site-wide: 5,440
  • In microbiology: 358
• Year to date:
  • Site-wide: 33,586
• Since beginning of last month:
  • Site-wide: 26,197

The S1/S2 boundary of SARS-CoV-2 spike protein modulates cell entry pathways and transmission

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  • Site-wide: 6,599
  • In microbiology: 406
• Year to date:
  • Site-wide: 29,097
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  • Site-wide: 68,684

Recapitulation of SARS-CoV-2 Infection and Cholangiocyte Damage with Human Liver Organoids

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  • Site-wide: 8,114
  • In cell biology: 158
• Year to date:
  • Site-wide: 112,690
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  • Site-wide: 84,081

Neutralization of recombinant RBD-subunit vaccine ZF2001-elicited antisera to SARS-CoV-2 variants including Delta

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  • Site-wide: 12,038
  • In immunology: 413
• Year to date:
  • Site-wide: 42,264
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  • Site-wide: 75,460

Clinical features and outcomes of 197 adult discharged patients with COIVD-19 in Yichang, Hubei

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  • Site-wide: 13,180
  • In epidemiology: 943
• Year to date:
  • Site-wide: 93,015
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  • Site-wide: 154,957

Protoporphyrin IX and verteporfin prevent SARS-CoV-2 infection in vitro and in a mouse model expressing human ACE2

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  • Site-wide: 14,534
  • In microbiology: 819
• Year to date:
  • Site-wide: 61,558
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  • Site-wide: 43,875

Immunization with the receptor-binding domain of SARS-CoV-2 elicits antibodies cross-neutralizing SARS-CoV-2 and SARS-CoV without antibody-dependent enhancement

• Downloaded 1,744 times
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  • Site-wide: 14,536
  • In microbiology: 796
• Year to date:
  • Site-wide: 109,234
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  • Site-wide: 152,756

Reduced sera neutralization to Omicron SARS-CoV-2 by bothinactivated and protein subunit vaccines and the convalescents

• Downloaded 1,522 times
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  • Site-wide: 17,895
  • In immunology: 729
• Year to date:
  • Site-wide: 3,629
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  • Site-wide: 22,913

A novel cell culture system modeling the SARS-CoV-2 life cycle

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  • Site-wide: 29,232
  • In microbiology: 1,652
• Year to date:
  • Site-wide: 78,706
• Since beginning of last month:
  • Site-wide: 44,888

Directed robust generation of functional retinal ganglion cells from Muller glia

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  • Site-wide: 31,541
  • In neuroscience: 3,985
• Year to date:
  • Site-wide: 54,549
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  • Site-wide: 58,706

ORF3a mediated-incomplete autophagy facilitates SARS-CoV-2 replication

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  • Site-wide: 35,467
  • In microbiology: 1,983
• Year to date:
  • Site-wide: 103,593
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  • Site-wide: 96,440

Exposure to violence, chronic stress, nasal DNA methylation, and atopic asthma in children

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  • Site-wide: 53,625
  • In respiratory medicine: 119
• Year to date:
  • Site-wide: 45,744
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  • Site-wide: 56,755

Topology-Dependent Interference of Circuit Function by Growth Feedback

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  • Site-wide: 55,392
  • In synthetic biology: 633
• Year to date:
  • Site-wide: 166,677
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  • Site-wide: 160,632

Configurable Compartmentation Enables In vitro Reconstitution of Sustained Synthetic Biology Systems

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  • Site-wide: 73,392
  • In synthetic biology: None
• Year to date:
  • Site-wide: 3,982
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  • Site-wide: 3,821

Characterization of SARS-CoV-2 variants B.1.617.1 (Kappa), B.1.617.2 (Delta) and B.1.618 on cell entry, host range, and sensitivity to convalescent plasma and ACE2 decoy receptor

• Downloaded 559 times
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  • Site-wide: 76,738
  • In microbiology: 5,015
• Year to date:
  • Site-wide: 48,512
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  • Site-wide: 63,640

Scalable total-evidence inference from molecular and continuous characters in a Bayesian framework

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  • Site-wide: 79,852
  • In systems biology: 1,769
• Year to date:
  • Site-wide: 57,020
• Since beginning of last month:
  • Site-wide: 56,611

Expression quantitative trait methylation analysis reveals methylomic associations with gene expression in childhood asthma

• Downloaded 512 times
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  • Site-wide: 85,305
  • In genomics: 5,315
• Year to date:
  • Site-wide: 100,846
• Since beginning of last month:
  • Site-wide: 112,677

Functional mapping of B-cell linear epitopes 1 of SARS-CoV-2 in COVID-19 convalescent population

• Downloaded 498 times
• Download rankings, all-time:
  • Site-wide: 88,018
  • In epidemiology: 3,652
• Year to date:
  • Site-wide: 124,190
• Since beginning of last month:
  • Site-wide: 103,241

Changes in the milk metabolome of the giant panda (Ailuropoda melanoleuca) with time after birth: Three phases in early lactation and progressive individual differences

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  • Site-wide: 92,430
  • In zoology: 282
• Year to date:
  • Site-wide: 178,836
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  • Site-wide: 147,352

Comparative analysis reveals the species-specific genetic determinants of ACE2 required for SARS-CoV-2 entry

• Downloaded 472 times
• Download rankings, all-time:
  • Site-wide: 93,559
  • In microbiology: 5,742
• Year to date:
  • Site-wide: 168,299
• Since beginning of last month:
  • Site-wide: 158,403

ROCK1/Drp1-mediated aberrant mitochondrial fission is crucial for dopaminergic nerve cell apoptosis

• Downloaded 436 times
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  • Site-wide: 101,670
  • In neuroscience: 14,059
• Year to date:
  • Site-wide: 147,379
• Since beginning of last month:
  • Site-wide: 172,421

Ultra-high-throughput microbial single-cell whole genome sequencing for genome-resolved metagenomics

• Downloaded 373 times
• Download rankings, all-time:
  • Site-wide: 117,493
  • In microbiology: None
• Year to date:
  • Site-wide: 7,809
• Since beginning of last month:
  • Site-wide: 22,298

Winner-Takes-All Resource Competition Redirects Cascading Cell Fate Transitions

• Downloaded 372 times
• Download rankings, all-time:
  • Site-wide: 117,673
  • In synthetic biology: 1,120
• Year to date:
  • Site-wide: 181,126
• Since beginning of last month:
  • Site-wide: 182,951

Changeover from signalling to energy-provisioning lipids during transition from colostrum to mature milk in the giant panda (Ailuropoda melanoleuca)

• Downloaded 371 times
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  • Site-wide: 117,916
  • In zoology: 406
• Year to date:
  • Site-wide: 178,840
• Since beginning of last month:
  • Site-wide: 177,236

Susceptibilities of human ACE2 genetic variants in coronavirus infection

• Downloaded 367 times
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  • Site-wide: 119,011
  • In microbiology: 8,291
• Year to date:
  • Site-wide: 90,600
• Since beginning of last month:
  • Site-wide: 106,656

Akt is required for artery formation during embryonic vascular development

• Downloaded 354 times
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  • Site-wide: 122,634
  • In developmental biology: 3,242
• Year to date:
  • Site-wide: 95,934
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  • Site-wide: 98,184

Resting-state functional MRI signal fluctuations are correlated with brain amyloid-β deposition

• Downloaded 350 times
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  • Site-wide: 123,933
  • In radiology and imaging: 298
• Year to date:
  • Site-wide: 48,961
• Since beginning of last month:
  • Site-wide: 22,146

Structural elucidation of the heterodimeric cis-prenyltransferase NgBR/DHDDS complex reveals novel insights in regulation of protein glycosylation

• Downloaded 339 times
• Download rankings, all-time:
  • Site-wide: 126,804
  • In biochemistry: 3,506
• Year to date:
  • Site-wide: 160,944
• Since beginning of last month:
  • Site-wide: 152,431

Mutation Y453F in the spike protein of SARS-CoV-2 enhances interaction with the mink ACE2 receptor for host adaption

• Downloaded 332 times
• Download rankings, all-time:
  • Site-wide: 128,926
  • In microbiology: 8,907
• Year to date:
  • Site-wide: 95,021
• Since beginning of last month:
  • Site-wide: 87,508

Infrequent intranasal oxytocin followed by positive social interaction improves symptoms in autistic children: a pilot randomized clinical trial

• Downloaded 329 times
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  • Site-wide: 129,558
  • In psychiatry and clinical psychology: 1,056
• Year to date:
  • Site-wide: 9,418
• Since beginning of last month:
  • Site-wide: 27,233

Double-edged role of resource competition in gene expression noise and control

• Downloaded 306 times
• Download rankings, all-time:
  • Site-wide: 136,596
  • In synthetic biology: 1,233
• Year to date:
  • Site-wide: 56,230
• Since beginning of last month:
  • Site-wide: 107,166

Adaptive dating and fast proposals: revisiting the phylogenetic relaxed clock model

• Downloaded 198 times
• Download rankings, all-time:
  • Site-wide: 167,238
  • In genetics: 5,929
• Year to date:
  • Site-wide: 171,185
• Since beginning of last month:
  • Site-wide: 186,992

Transcutaneous auricular vagus nerve stimulation increases eye-gaze on salient facial features and oxytocin release

• Downloaded 167 times
• Download rankings, all-time:
  • Site-wide: 174,645
  • In neuroscience: 25,237
• Year to date:
  • Site-wide: 65,987
• Since beginning of last month:
  • Site-wide: 52,622

A brain structural connectivity biomarker for diagnosis of autism spectrum disorder in early childhood

• Downloaded 160 times
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  • Site-wide: 176,172
  • In psychiatry and clinical psychology: 1,120
• Year to date:
  • Site-wide: 67,137
• Since beginning of last month:
  • Site-wide: 44,572

Inflammatory stress signaling via NF-kB alters accessible cholesterol to upregulate SREBP2 transcriptional activity in endothelial cells

• Downloaded 141 times
• Download rankings, all-time:
  • Site-wide: 179,776
  • In cell biology: None
• Year to date:
  • Site-wide: 31,432
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  • Site-wide: 4,760

Higher knee hypertension in patients with hemiplegia correlates lower lateral and medial meniscus volume in the paretic leg

• Downloaded 127 times
• Download rankings, all-time:
  • Site-wide: 182,124
  • In rehabilitation medicine and physical therapy: 227
• Year to date:
  • Site-wide: 35,741
• Since beginning of last month:
  • Site-wide: 24,061