Author: Michael Inouye

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Preprints

OGUs enable effective, phylogeny-aware analysis of even shallow metagenome community structures

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Genomic risk prediction of coronary artery disease in nearly 500,000 adults: implications for early screening and primary prevention

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Taxonomic Signatures of Long-Term Mortality Risk in Human Gut Microbiota

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Correcting index databases improves metagenomic studies

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Fast Principal Component Analysis of Large-Scale Genome-Wide Data

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Improving reporting standards for polygenic scores in risk prediction studies

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The Polygenic and Monogenic Basis of Blood Traits and Diseases

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Bacterial modification of the host glycosaminoglycan heparan sulfate modulates SARS-CoV-2 infectivity

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Integrative analysis of the plasma proteome and polygenic risk of cardiometabolic diseases

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Elevated alpha-1 antitrypsin is a major component of GlycA-associated risk for future morbidity and mortality

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Epistasis within the MHC contributes to the genetic architecture of celiac disease

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SRST2: Rapid genomic surveillance for public health and hospital microbiology labs

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Learning polygenic scores for human blood cell traits

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The Polygenic Score Catalog: an open database for reproducibility and systematic evaluation

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FlashPCA2: principal component analysis of biobank-scale genotype datasets

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The carbon footprint of bioinformatics

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Genomic analysis of Mycobacterium tuberculosis reveals complex etiology of tuberculosis in Vietnam including frequent introduction and transmission of Beijing lineage and positive selection for EsxW Beijing variant

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Identification of Brain Expression Quantitative Trait Loci Associated with Schizophrenia and Affective Disorders in Normal Brain Tissue

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Power, false discovery rate and Winner's Curse in eQTL studies

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Genetic loci associated with coronary artery disease harbor evidence of selection and antagonistic pleiotropy

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Genomic prediction of coronary heart disease

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The infant airway microbiome in health and disease impacts later asthma development

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Use of polygenic risk scores and other molecular markers to enhance cardiovascular risk prediction: Prospective cohort study and modelling analysis

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Multivariate genome-wide association analysis of a cytokine network reveals variants with widespread immune, haematological and cardiometabolic pleiotropy

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Genome-wide association and Mendelian randomization analysis prioritizes bioactive metabolites with putative causal effects on common diseases

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Combined effects of host genetics and diet on human gut microbiota and incident disease in a single population cohort

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EcOH: In silico serotyping of E. coli from short read data

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Towards a molecular systems model of coronary artery disease

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Dynamics of the upper airway microbiome in the pathogenesis of asthma-associated persistent wheeze in preschool children

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FlashPCA: fast sparse canonical correlation analysis of genomic data

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Genomic risk score offers predictive performance comparable to clinical risk factors for ischaemic stroke

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A scalable permutation approach reveals replication and preservation patterns of gene coexpression modules

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An interaction map of circulating metabolites, immune gene networks and their genetic regulation

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FastSpar: Rapid and scalable correlation estimation for compositional data

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Links between gut microbiome composition and fatty liver disease in a large population sample

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Exploratory analysis and error modeling of a sequencing technology

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GeneMates: an R package for Detecting Horizontal Gene Co-transfer between Bacteria Using Gene-gene Associations Controlled for Population Structure

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Early prediction of liver disease using conventional risk factors and gut microbiome-augmented gradient boosting

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Systems medicine links microbial inflammatory response with glycoprotein-associated mortality risk

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Genome-wide analysis of genetic risk factors for rheumatic heart disease in Aboriginal Australians provides support for pathogenic molecular mimicry

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Non-parametric mixture models identify trajectories of childhood immune development relevant to asthma and allergy

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The landscape of incident disease risk for the biomarker GlycA and its mortality stratification in angiography patients

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Genomic risk scores for juvenile idiopathic arthritis and its subtypes

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Neonatal genetics of gene expression reveal the origins of autoimmune and allergic disease risk

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A polygenic risk score for coronary heart disease performs well in individuals aged 70 years and older

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