Author: Gad Abraham

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Preprints

Genomic risk prediction of coronary artery disease in nearly 500,000 adults: implications for early screening and primary prevention

• Downloaded 4,098 times
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  • Site-wide: 2,618
  • In genetics: 100
• Year to date:
  • Site-wide: 41,449
• Since beginning of last month:
  • Site-wide: 58,385

Fast Principal Component Analysis of Large-Scale Genome-Wide Data

• Downloaded 2,117 times
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  • Site-wide: 6,832
  • In genomics: 758
• Year to date:
  • Site-wide: 77,913
• Since beginning of last month:
  • Site-wide: 79,672

Integrative analysis of the plasma proteome and polygenic risk of cardiometabolic diseases

• Downloaded 1,763 times
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  • Site-wide: 8,990
  • In genetics: 428
• Year to date:
  • Site-wide: 5,213
• Since beginning of last month:
  • Site-wide: 3,197

Elevated alpha-1 antitrypsin is a major component of GlycA-associated risk for future morbidity and mortality

• Downloaded 1,706 times
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  • Site-wide: 9,467
  • In systems biology: 179
• Year to date:
  • Site-wide: 21,463
• Since beginning of last month:
  • Site-wide: 35,771

Epistasis within the MHC contributes to the genetic architecture of celiac disease

• Downloaded 1,610 times
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  • Site-wide: 10,277
  • In genomics: 1,118
• Year to date:
  • Site-wide: 68,884
• Since beginning of last month:
  • Site-wide: 114,717

The Polygenic Score Catalog: an open database for reproducibility and systematic evaluation

• Downloaded 1,366 times
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  • Site-wide: 13,121
  • In genetic and genomic medicine: 46
• Year to date:
  • Site-wide: 5,113
• Since beginning of last month:
  • Site-wide: 5,254

Genomic prediction of celiac disease targeting HLA-positive individuals

• Downloaded 1,330 times
• Download rankings, all-time:
  • Site-wide: 13,649
  • In genomics: 1,452
• Year to date:
  • Site-wide: 81,257
• Since beginning of last month:
  • Site-wide: 123,138

FlashPCA2: principal component analysis of biobank-scale genotype datasets

• Downloaded 1,304 times
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  • Site-wide: 14,071
  • In genomics: 1,491
• Year to date:
  • Site-wide: 55,262
• Since beginning of last month:
  • Site-wide: 58,319

Genetic loci associated with coronary artery disease harbor evidence of selection and antagonistic pleiotropy

• Downloaded 1,182 times
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  • Site-wide: 16,329
  • In genomics: 1,690
• Year to date:
  • Site-wide: 64,330
• Since beginning of last month:
  • Site-wide: 58,291

Genomic prediction of coronary heart disease

• Downloaded 1,164 times
• Download rankings, all-time:
  • Site-wide: 16,701
  • In genomics: 1,735
• Year to date:
  • Site-wide: 113,708
• Since beginning of last month:
  • Site-wide: 108,715

Use of polygenic risk scores and other molecular markers to enhance cardiovascular risk prediction: Prospective cohort study and modelling analysis

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  • Site-wide: 18,766
  • In genomics: 1,907
• Year to date:
  • Site-wide: 48,075
• Since beginning of last month:
  • Site-wide: 49,984

Multivariate genome-wide association analysis of a cytokine network reveals variants with widespread immune, haematological and cardiometabolic pleiotropy

• Downloaded 956 times
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  • Site-wide: 22,251
  • In genomics: 2,183
• Year to date:
  • Site-wide: 87,637
• Since beginning of last month:
  • Site-wide: 91,911

Towards a molecular systems model of coronary artery disease

• Downloaded 826 times
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  • Site-wide: 27,413
  • In systems biology: 585
• Year to date:
  • Site-wide: 117,075
• Since beginning of last month:
  • Site-wide: 108,746

FlashPCA: fast sparse canonical correlation analysis of genomic data

• Downloaded 790 times
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  • Site-wide: 29,174
  • In genomics: 2,664
• Year to date:
  • Site-wide: 102,896
• Since beginning of last month:
  • Site-wide: 79,949

Genomic risk score offers predictive performance comparable to clinical risk factors for ischaemic stroke

• Downloaded 788 times
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  • Site-wide: 29,279
  • In genomics: 2,667
• Year to date:
  • Site-wide: 108,718
• Since beginning of last month:
  • Site-wide: 100,823

A scalable permutation approach reveals replication and preservation patterns of gene coexpression modules

• Downloaded 779 times
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  • Site-wide: 29,735
  • In bioinformatics: 3,402
• Year to date:
  • Site-wide: 124,737
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  • Site-wide: 116,264

An interaction map of circulating metabolites, immune gene networks and their genetic regulation

• Downloaded 767 times
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  • Site-wide: 30,418
  • In genomics: 2,746
• Year to date:
  • Site-wide: 108,559
• Since beginning of last month:
  • Site-wide: 87,837

Systems medicine links microbial inflammatory response with glycoprotein-associated mortality risk

• Downloaded 527 times
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  • Site-wide: 49,366
  • In genomics: 3,893
• Year to date:
  • Site-wide: 125,785
• Since beginning of last month:
  • Site-wide: 131,838

Genomic risk scores for juvenile idiopathic arthritis and its subtypes

• Downloaded 448 times
• Download rankings, all-time:
  • Site-wide: 59,236
  • In rheumatology: 33
• Year to date:
  • Site-wide: 89,902
• Since beginning of last month:
  • Site-wide: 95,694

A polygenic risk score for coronary heart disease performs well in individuals aged 70 years and older

• Downloaded 81 times
• Download rankings, all-time:
  • Site-wide: 129,772
  • In genetic and genomic medicine: 637
• Year to date:
  • Site-wide: 30,981
• Since beginning of last month:
  • Site-wide: 9,307