Author: Gad Abraham

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Preprints

Genomic risk prediction of coronary artery disease in nearly 500,000 adults: implications for early screening and primary prevention

• Downloaded 4,148 times
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  • Site-wide: 3,066
  • In genetics: 103
• Year to date:
  • Site-wide: 58,065
• Since beginning of last month:
  • Site-wide: None

Integrative analysis of the plasma proteome and polygenic risk of cardiometabolic diseases

• Downloaded 2,158 times
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  • Site-wide: 7,824
  • In genetics: 344
• Year to date:
  • Site-wide: 5,025
• Since beginning of last month:
  • Site-wide: 10,668

Fast Principal Component Analysis of Large-Scale Genome-Wide Data

• Downloaded 2,139 times
• Download rankings, all-time:
  • Site-wide: 7,921
  • In genomics: 826
• Year to date:
  • Site-wide: 105,746
• Since beginning of last month:
  • Site-wide: 43,348

Elevated alpha-1 antitrypsin is a major component of GlycA-associated risk for future morbidity and mortality

• Downloaded 1,777 times
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  • Site-wide: 10,421
  • In systems biology: 187
• Year to date:
  • Site-wide: 33,312
• Since beginning of last month:
  • Site-wide: 79,361

Epistasis within the MHC contributes to the genetic architecture of celiac disease

• Downloaded 1,643 times
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  • Site-wide: 11,710
  • In genomics: 1,198
• Year to date:
  • Site-wide: 89,154
• Since beginning of last month:
  • Site-wide: 62,992

The Polygenic Score Catalog: an open database for reproducibility and systematic evaluation

• Downloaded 1,580 times
• Download rankings, all-time:
  • Site-wide: 12,356
  • In genetic and genomic medicine: 50
• Year to date:
  • Site-wide: 7,594
• Since beginning of last month:
  • Site-wide: 16,073

Genomic prediction of celiac disease targeting HLA-positive individuals

• Downloaded 1,350 times
• Download rankings, all-time:
  • Site-wide: 15,666
  • In genomics: 1,556
• Year to date:
  • Site-wide: 111,187
• Since beginning of last month:
  • Site-wide: None

FlashPCA2: principal component analysis of biobank-scale genotype datasets

• Downloaded 1,339 times
• Download rankings, all-time:
  • Site-wide: 15,859
  • In genomics: 1,577
• Year to date:
  • Site-wide: 77,170
• Since beginning of last month:
  • Site-wide: 62,215

Genetic loci associated with coronary artery disease harbor evidence of selection and antagonistic pleiotropy

• Downloaded 1,206 times
• Download rankings, all-time:
  • Site-wide: 18,522
  • In genomics: 1,804
• Year to date:
  • Site-wide: 95,206
• Since beginning of last month:
  • Site-wide: 62,440

Genomic prediction of coronary heart disease

• Downloaded 1,181 times
• Download rankings, all-time:
  • Site-wide: 19,114
  • In genomics: 1,864
• Year to date:
  • Site-wide: 131,763
• Since beginning of last month:
  • Site-wide: None

Use of polygenic risk scores and other molecular markers to enhance cardiovascular risk prediction: Prospective cohort study and modelling analysis

• Downloaded 1,113 times
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  • Site-wide: 20,873
  • In genomics: 1,996
• Year to date:
  • Site-wide: 70,652
• Since beginning of last month:
  • Site-wide: 88,702

Multivariate genome-wide association analysis of a cytokine network reveals variants with widespread immune, haematological and cardiometabolic pleiotropy

• Downloaded 981 times
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  • Site-wide: 25,101
  • In genomics: 2,331
• Year to date:
  • Site-wide: 107,923
• Since beginning of last month:
  • Site-wide: None

Towards a molecular systems model of coronary artery disease

• Downloaded 841 times
• Download rankings, all-time:
  • Site-wide: 31,189
  • In systems biology: 646
• Year to date:
  • Site-wide: 136,705
• Since beginning of last month:
  • Site-wide: 79,562

FlashPCA: fast sparse canonical correlation analysis of genomic data

• Downloaded 826 times
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  • Site-wide: 32,019
  • In genomics: 2,792
• Year to date:
  • Site-wide: 100,226
• Since beginning of last month:
  • Site-wide: None

Genomic risk score offers predictive performance comparable to clinical risk factors for ischaemic stroke

• Downloaded 814 times
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  • Site-wide: 32,662
  • In genomics: 2,837
• Year to date:
  • Site-wide: 116,119
• Since beginning of last month:
  • Site-wide: 87,098

A scalable permutation approach reveals replication and preservation patterns of gene coexpression modules

• Downloaded 801 times
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  • Site-wide: 33,437
  • In bioinformatics: 3,708
• Year to date:
  • Site-wide: 130,641
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  • Site-wide: None

An interaction map of circulating metabolites, immune gene networks and their genetic regulation

• Downloaded 794 times
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  • Site-wide: 33,851
  • In genomics: 2,890
• Year to date:
  • Site-wide: 114,946
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  • Site-wide: None

Systems medicine links microbial inflammatory response with glycoprotein-associated mortality risk

• Downloaded 539 times
• Download rankings, all-time:
  • Site-wide: 55,956
  • In genomics: 4,193
• Year to date:
  • Site-wide: 144,554
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  • Site-wide: None

Genomic risk scores for juvenile idiopathic arthritis and its subtypes

• Downloaded 474 times
• Download rankings, all-time:
  • Site-wide: 64,732
  • In rheumatology: 48
• Year to date:
  • Site-wide: 108,306
• Since beginning of last month:
  • Site-wide: 46,256

A polygenic risk score for coronary heart disease performs well in individuals aged 70 years and older

• Downloaded 166 times
• Download rankings, all-time:
  • Site-wide: 129,951
  • In genetic and genomic medicine: 692
• Year to date:
  • Site-wide: 37,550
• Since beginning of last month:
  • Site-wide: 100,585