Rxivist combines preprints from bioRxiv with data from Twitter to help you find the papers being discussed in your field. Currently indexing 62,747 bioRxiv papers from 278,434 authors.

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Preprints

Genetic analysis of over one million people identifies 535 novel loci for blood pressure.

• Downloaded 2,743 times
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  • Site-wide: 1,273 out of 62,747
  • In genetics: 121 out of 3,562
• Year to date:
  • Site-wide: 13,420 out of 62,747
• Since beginning of last month:
  • Site-wide: 26,734 out of 62,747

Quantifying the impact of rare and ultra-rare coding variation across the phenotypic spectrum

• Downloaded 1,854 times
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  • Site-wide: 2,549 out of 62,747
  • In genetics: 236 out of 3,562
• Year to date:
  • Site-wide: 27,438 out of 62,747
• Since beginning of last month:
  • Site-wide: 21,557 out of 62,747

Polygenic and clinical risk scores and their impact on age at onset of cardiometabolic diseases and common cancers

• Downloaded 1,530 times
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  • Site-wide: 3,516 out of 62,747
  • In genomics: 664 out of 4,316
• Year to date:
  • Site-wide: 679 out of 62,747
• Since beginning of last month:
  • Site-wide: 923 out of 62,747

Human loss-of-function variants suggest that partial LRRK2 inhibition is a safe therapeutic strategy for Parkinson’s disease

• Downloaded 1,283 times
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  • Site-wide: 4,698 out of 62,747
  • In genomics: 832 out of 4,316
• Year to date:
  • Site-wide: 947 out of 62,747
• Since beginning of last month:
  • Site-wide: 1,602 out of 62,747

Genomic prediction of coronary heart disease

• Downloaded 1,061 times
• Download rankings, all-time:
  • Site-wide: 6,449 out of 62,747
  • In genomics: 1,061 out of 4,316
• Year to date:
  • Site-wide: 55,446 out of 62,747
• Since beginning of last month:
  • Site-wide: 57,999 out of 62,747

Refining fine-mapping: effect sizes and regional heritability

• Downloaded 993 times
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  • Site-wide: 7,161 out of 62,747
  • In genetics: 560 out of 3,562
• Year to date:
  • Site-wide: 7,258 out of 62,747
• Since beginning of last month:
  • Site-wide: 12,734 out of 62,747

Exome sequencing identifies high-impact trait-associated alleles enriched in Finns

• Downloaded 958 times
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  • Site-wide: 7,572 out of 62,747
  • In genomics: 1,201 out of 4,316
• Year to date:
  • Site-wide: 4,096 out of 62,747
• Since beginning of last month:
  • Site-wide: 21,052 out of 62,747

Haplotype sharing provides insights into fine-scale population history and disease in Finland

• Downloaded 938 times
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  • Site-wide: 7,833 out of 62,747
  • In genetics: 610 out of 3,562
• Year to date:
  • Site-wide: 37,704 out of 62,747
• Since beginning of last month:
  • Site-wide: 43,765 out of 62,747

Genetics of human plasma lipidome: Understanding lipid metabolism and its link to diseases beyond traditional lipids

• Downloaded 865 times
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  • Site-wide: 8,923 out of 62,747
  • In genetics: 667 out of 3,562
• Year to date:
  • Site-wide: 4,465 out of 62,747
• Since beginning of last month:
  • Site-wide: 4,695 out of 62,747

Geographic variation and bias in polygenic scores of complex diseases and traits in Finland

• Downloaded 829 times
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  • Site-wide: 9,539 out of 62,747
  • In genetics: 706 out of 3,562
• Year to date:
  • Site-wide: 4,957 out of 62,747
• Since beginning of last month:
  • Site-wide: 18,695 out of 62,747

Circulating metabolites and the risk of type 2 diabetes: a prospective study of 11,896 young adults from four Finnish cohorts

• Downloaded 760 times
• Download rankings, all-time:
  • Site-wide: 10,828 out of 62,747
  • In epidemiology: 119 out of 1,556
• Year to date:
  • Site-wide: 2,374 out of 62,747
• Since beginning of last month:
  • Site-wide: 8,786 out of 62,747

Elevated alpha-1 antitrypsin is a major component of GlycA-associated risk for future morbidity and mortality

• Downloaded 748 times
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  • Site-wide: 11,064 out of 62,747
  • In systems biology: 316 out of 1,783
• Year to date:
  • Site-wide: 4,245 out of 62,747
• Since beginning of last month:
  • Site-wide: 5,214 out of 62,747

Multivariate genome-wide association analysis of a cytokine network reveals variants with widespread immune, haematological and cardiometabolic pleiotropy

• Downloaded 686 times
• Download rankings, all-time:
  • Site-wide: 12,569 out of 62,747
  • In genomics: 1,728 out of 4,316
• Year to date:
  • Site-wide: 2,842 out of 62,747
• Since beginning of last month:
  • Site-wide: 9,879 out of 62,747

An interaction map of circulating metabolites, immune gene networks and their genetic regulation

• Downloaded 663 times
• Download rankings, all-time:
  • Site-wide: 13,174 out of 62,747
  • In genomics: 1,784 out of 4,316
• Year to date:
  • Site-wide: 57,381 out of 62,747
• Since beginning of last month:
  • Site-wide: 53,225 out of 62,747

Novel blood pressure locus and gene discovery using GWAS and expression datasets from blood and the kidney

• Downloaded 588 times
• Download rankings, all-time:
  • Site-wide: 15,553 out of 62,747
  • In genomics: 1,971 out of 4,316
• Year to date:
  • Site-wide: 41,584 out of 62,747
• Since beginning of last month:
  • Site-wide: 45,656 out of 62,747

Rare protein-altering variants in ANGPTL7 lower intraocular pressure and protect against glaucoma

• Downloaded 552 times
• Download rankings, all-time:
  • Site-wide: 16,910 out of 62,747
  • In genetics: 1,147 out of 3,562
• Year to date:
  • Site-wide: 4,138 out of 62,747
• Since beginning of last month:
  • Site-wide: 4,944 out of 62,747

Systems medicine links microbial inflammatory response with glycoprotein-associated mortality risk

• Downloaded 435 times
• Download rankings, all-time:
  • Site-wide: 22,650 out of 62,747
  • In genomics: 2,501 out of 4,316
• Year to date:
  • Site-wide: 54,993 out of 62,747
• Since beginning of last month:
  • Site-wide: 58,159 out of 62,747

Polygenic risk score of alcohol consumption predicts alcohol-related morbidity and all-cause mortality

• Downloaded 330 times
• Download rankings, all-time:
  • Site-wide: 30,225 out of 62,747
  • In genomics: 2,972 out of 4,316
• Year to date:
  • Site-wide: 9,782 out of 62,747
• Since beginning of last month:
  • Site-wide: 17,377 out of 62,747

The landscape of incident disease risk for the biomarker GlycA and its mortality stratification in angiography patients

• Downloaded 316 times
• Download rankings, all-time:
  • Site-wide: 31,400 out of 62,747
  • In epidemiology: 488 out of 1,556
• Year to date:
  • Site-wide: 43,120 out of 62,747
• Since beginning of last month:
  • Site-wide: 50,374 out of 62,747

Multi-ancestry GWAS of the electrocardiographic PR interval identifies 210 loci underlying cardiac conduction

• Downloaded 264 times
• Download rankings, all-time:
  • Site-wide: 36,624 out of 62,747
  • In genetics: 2,270 out of 3,562
• Year to date:
  • Site-wide: 13,760 out of 62,747
• Since beginning of last month:
  • Site-wide: 10,514 out of 62,747

Genetic variation in apolipoprotein A-I concentrations and risk of coronary artery disease

• Downloaded 211 times
• Download rankings, all-time:
  • Site-wide: 42,678 out of 62,747
  • In epidemiology: 785 out of 1,556
• Year to date:
  • Site-wide: 18,610 out of 62,747
• Since beginning of last month:
  • Site-wide: 37,496 out of 62,747

Coronary artery disease risk and lipidomic profiles are similar in familial and population-ascertained hyperlipidemias

• Downloaded 186 times
• Download rankings, all-time:
  • Site-wide: 45,778 out of 62,747
  • In epidemiology: 898 out of 1,556
• Year to date:
  • Site-wide: 47,729 out of 62,747
• Since beginning of last month:
  • Site-wide: 49,074 out of 62,747

Polygenic Hyperlipidemias and Coronary Artery Disease Risk

• Downloaded 107 times
• Download rankings, all-time:
  • Site-wide: 56,183 out of 62,747
  • In genomics: 4,103 out of 4,316
• Year to date:
  • Site-wide: 38,076 out of 62,747
• Since beginning of last month:
  • Site-wide: 22,758 out of 62,747