Rxivist combines preprints from bioRxiv with data from Twitter to help you find the papers being discussed in your field. Currently indexing 57,915 bioRxiv papers from 266,490 authors.

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Preprints

Polygenic Hyperlipidemias and Coronary Artery Disease Risk

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Genetic analysis of over one million people identifies 535 novel loci for blood pressure.

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Quantifying the impact of rare and ultra-rare coding variation across the phenotypic spectrum

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Polygenic and clinical risk scores and their impact on age at onset of cardiometabolic diseases and common cancers

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Human loss-of-function variants suggest that partial LRRK2 inhibition is a safe therapeutic strategy for Parkinsons disease

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  • In genomics: 941 out of 4,058
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Genome-wide association study identifies 17 new loci influencing concentrations of circulating cytokines and growth factors

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  • In genomics: 953 out of 4,058
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Genomic prediction of coronary heart disease

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Haplotype sharing provides insights into fine-scale population history and disease in Finland

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  • In genetics: 588 out of 3,319
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Exome sequencing identifies high-impact trait-associated alleles enriched in Finns

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Geographic variation and bias in polygenic scores of complex diseases and traits in Finland

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Genetics of human plasma lipidome: Understanding lipid metabolism and its link to diseases beyond traditional lipids

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  • In genetics: 724 out of 3,319
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Circulating metabolites and the risk of type 2 diabetes: a prospective study of 11,896 young adults from four Finnish cohorts

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  • In epidemiology: 127 out of 1,556
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An interaction map of circulating metabolites, immune gene networks and their genetic regulation

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Elevated alpha-1 antitrypsin is a major component of GlycA-associated risk for future morbidity and mortality

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  • In systems biology: 372 out of 1,638
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Multivariate genome-wide association analysis of a cytokine network reveals variants with widespread immune, haematological and cardiometabolic pleiotropy

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  • In genomics: 1,793 out of 4,058
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Novel blood pressure locus and gene discovery using GWAS and expression datasets from blood and the kidney

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  • In genomics: 1,902 out of 4,058
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Rare protein-altering variants in ANGPTL7 lower intraocular pressure and protect against glaucoma

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  • In genetics: 1,417 out of 3,319
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Systems medicine links microbial inflammatory response with glycoprotein-associated mortality risk

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  • In genomics: 2,408 out of 4,058
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The landscape of incident disease risk for the biomarker GlycA and its mortality stratification in angiography patients

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  • In epidemiology: 467 out of 1,556
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Polygenic risk score of alcohol consumption predicts alcohol-related morbidity and all-cause mortality

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  • In genomics: 2,998 out of 4,058
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  • Site-wide: 7,493 out of 57,915

Genetic variation in apolipoprotein A-I concentrations and risk of coronary artery disease

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  • In epidemiology: 757 out of 1,556
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  • Site-wide: 15,944 out of 57,915
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  • Site-wide: 34,424 out of 57,915

Coronary artery disease risk and lipidomic profiles are similar in familial and population-ascertained hyperlipidemias

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  • Site-wide: 43,310 out of 57,915
  • In epidemiology: 843 out of 1,556
• Year to date:
  • Site-wide: 43,380 out of 57,915
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  • Site-wide: 42,509 out of 57,915

Multi-ancestry GWAS of the electrocardiographic PR interval identifies 210 loci underlying cardiac conduction

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  • In genetics: 2,723 out of 3,319
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  • Site-wide: 2,044 out of 57,915