Author: Mika Kähönen

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Preprints

Unraveling the polygenic architecture of complex traits using blood eQTL meta-analysis

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Ninety-nine independent genetic loci influencing general cognitive function include genes associated with brain health and structure (N = 280,360)

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Genetic analysis of over one million people identifies 535 novel loci for blood pressure.

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Integrative approaches for large-scale transcriptome-wide association studies

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Trans-ethnic and ancestry-specific blood-cell genetics in 746,667 individuals from 5 global populations

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The Polygenic and Monogenic Basis of Blood Traits and Diseases

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New genetic signals for lung function highlight pathways and pleiotropy, and chronic obstructive pulmonary disease associations across multiple ancestries

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Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

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Genome-wide association and functional studies identify 46 novel loci for alcohol consumption and suggest common genetic mechanisms with neuropsychiatric disorders

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Genome-wide association studies identify 137 loci for DNA methylation biomarkers of ageing

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Circulating metabolites and the risk of type 2 diabetes: a prospective study of 11,896 young adults from four Finnish cohorts

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An epigenome-wide association study of educational attainment (n = 10,767)

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Multivariate genome-wide association analysis of a cytokine network reveals variants with widespread immune, haematological and cardiometabolic pleiotropy

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Lower hemoglobin levels associate with lower body mass index and healthier metabolic profile

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Atrial Fibrillation Genetic Risk Differentiates Cardioembolic Stroke from other Stroke Subtypes

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An interaction map of circulating metabolites, immune gene networks and their genetic regulation

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Novel blood pressure locus and gene discovery using GWAS and expression datasets from blood and the kidney

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Genetic and environmental perturbations lead to regulatory decoherence

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Multi-ancestry GWAS of the electrocardiographic PR interval identifies 210 loci underlying cardiac conduction

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Metabolic profiling of alcohol consumption in 9778 young adults

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Metabolic Effects Of Risk Alleles In PNPLA3, TM6SF2, GCKR, And LYPLAL1 Inform About Heterogeneity Of Non-Alcoholic Fatty Liver Disease

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Discovering patterns of pleiotropy in genome-wide association studies

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Genome-wide association meta-analysis of PR interval identifies 47 novel loci associated with atrial and atrioventricular electrical activity

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Metabolic signatures of birth weight in 18288 adolescents and adults

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Systems medicine links microbial inflammatory response with glycoprotein-associated mortality risk

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Meta-analysis of exome array data identifies six novel genetic loci for lung function

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  • Site-wide: 55,735
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The landscape of incident disease risk for the biomarker GlycA and its mortality stratification in angiography patients

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Lipoprotein Signatures of Cholesteryl Ester Transfer Protein and HMG-CoA Reductase Inhibition

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Genetic variation in apolipoprotein A-I concentrations and risk of coronary artery disease

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Genome-wide analysis of 102,084 migraine cases identifies 123 risk loci and subtype-specific risk alleles

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Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure

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Gene regulation contributes to explain the impact of early life socioeconomic disadvantage on adult inflammatory levels in two European cohort studies

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Elevated glycoprotein acetyl levels in adolescence and early adulthood predict adverse cardiometabolic profiles and risk of metabolic syndrome in up to 10 year follow-up

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