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Author: Tanja Kortemme

Rankings

  • All-time downloads: 201,690 (rank: 533 )
  • Categories:
    • bioengineering: 5,542 (rank: 273 )
    • bioinformatics: 1,187 (rank: 15,791 (tie) )
    • biophysics: 11,474 (rank: 141 )
    • synthetic biology: 2,582 (rank: 718 (tie) )
    • systems biology: 180,905 (rank: 8 )

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Preprints

A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing

systems biology more details view paper
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    • Site-wide: 30
    • In systems biology: 1
  • Year to date:
    • Site-wide: 1,563
  • Since beginning of last month:
    • Site-wide: 1,083

The Rosetta all-atom energy function for macromolecular modeling and design

biophysics more details view paper
  • Downloaded 3,110 times
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    • Site-wide: 5,464
    • In biophysics: 80
  • Year to date:
    • Site-wide: 149,771
  • Since beginning of last month:
    • Site-wide: 67,506

CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes.

biophysics more details view paper
  • Downloaded 2,951 times
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    • Site-wide: 5,922
    • In biophysics: 92
  • Year to date:
    • Site-wide: 2,493
  • Since beginning of last month:
    • Site-wide: 3,650

Controlling CRISPR-Cas9 with ligand-activated and ligand-deactivated sgRNAs

synthetic biology more details view paper
  • Downloaded 2,582 times
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    • Site-wide: 7,184
    • In synthetic biology: 71
  • Year to date:
    • Site-wide: 101,942
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    • Site-wide: 121,900

Engineered ACE2 receptor traps potently neutralize SARS-CoV-2

bioengineering more details view paper
  • Downloaded 2,264 times
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    • Site-wide: 8,715
    • In bioengineering: 138
  • Year to date:
    • Site-wide: 117,291
  • Since beginning of last month:
    • Site-wide: 44,210

Flex ddG: Rosetta ensemble-based estimation of changes in protein-protein binding affinity upon mutation

biophysics more details view paper
  • Downloaded 1,671 times
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    • Site-wide: 13,629
    • In biophysics: 311
  • Year to date:
    • Site-wide: 42,313
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    • Site-wide: 52,078

Biophysical basis of cellular multi-specificity encoded in a model molecular switch

systems biology more details view paper
  • Downloaded 1,462 times
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    • Site-wide: 16,732
    • In systems biology: 291
  • Year to date:
    • Site-wide: 14,929
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    • Site-wide: 58,159

Quantitative mapping of protein-peptide affinity landscapes using spectrally encoded beads

bioengineering more details view paper
  • Downloaded 1,425 times
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    • Site-wide: 17,396
    • In bioengineering: 299
  • Year to date:
    • Site-wide: 81,527
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Computational design of a modular protein sense/response system

biophysics more details view paper
  • Downloaded 1,221 times
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    • Site-wide: 21,978
    • In biophysics: 561
  • Year to date:
    • Site-wide: 81,141
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    • Site-wide: 146,837

Expanding the space of protein geometries by computational design of de novo fold families

bioengineering more details view paper
  • Downloaded 1,026 times
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    • Site-wide: 28,562
    • In bioengineering: 511
  • Year to date:
    • Site-wide: None
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    • Site-wide: 90,809

Comparison of Rosetta flexible-backbone computational protein design methods on binding interactions

biophysics more details view paper
  • Downloaded 980 times
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    • Site-wide: 30,600
    • In biophysics: 892
  • Year to date:
    • Site-wide: 57,161
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    • Site-wide: 81,328

Determination of Ubiquitin Fitness Landscapes Under Different Chemical Stresses in a Classroom Setting

systems biology more details view paper
  • Downloaded 940 times
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    • Site-wide: 32,546
    • In systems biology: 643
  • Year to date:
    • Site-wide: 54,558
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    • Site-wide: 122,109

Accurately positioning functional residues with robotics-inspired computational protein design

bioengineering more details view paper
  • Downloaded 827 times
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    • Site-wide: 39,281
    • In bioengineering: 747
  • Year to date:
    • Site-wide: 51,745
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    • Site-wide: 3,111

Modulating the cellular context broadly reshapes the mutational landscape of a model enzyme

biophysics more details view paper
  • Downloaded 773 times
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    • Site-wide: 43,248
    • In biophysics: 1,381
  • Year to date:
    • Site-wide: 141,978
  • Since beginning of last month:
    • Site-wide: 131,296

Extending Chemical Perturbations Of The Ubiquitin Fitness Landscape In A Classroom Setting

bioinformatics more details view paper
  • Downloaded 633 times
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    • Site-wide: 56,898
    • In bioinformatics: 5,615
  • Year to date:
    • Site-wide: 97,053
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    • Site-wide: 152,874

Ensuring scientific reproducibility in bio-macromolecular modeling via extensive, automated benchmarks

bioinformatics more details view paper
  • Downloaded 554 times
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    • Site-wide: 67,442
    • In bioinformatics: 6,404
  • Year to date:
    • Site-wide: 69,321
  • Since beginning of last month:
    • Site-wide: 20,463

De novo protein fold families expand the designable ligand binding site space

biophysics more details view paper
  • Downloaded 429 times
  • Download rankings, all-time:
    • Site-wide: 89,717
    • In biophysics: 3,314
  • Year to date:
    • Site-wide: 36,998
  • Since beginning of last month:
    • Site-wide: 38,663

Ligand-induced changes in dynamics mediate long-range allostery in the lac repressor

biophysics more details view paper
  • Downloaded 339 times
  • Download rankings, all-time:
    • Site-wide: 110,569
    • In biophysics: 4,217
  • Year to date:
    • Site-wide: 21,711
  • Since beginning of last month:
    • Site-wide: 981

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