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Author: Jennifer A. Doudna

  • ORCiD: http://orcid.org/0000-0001-9161-999X
  • Most recently observed institution: Department of Molecular and Cell Biology, University of California Berkeley, Berkeley, CA 94720, USA; Department of Chemistry, University of California Berkeley, Berkeley, CA, 94720, USA; Innovative Genomics Initiative, University of California Berkeley,

Rankings

  • All-time downloads: 32,690 (rank: 1,282 out of 381,058)
  • Categories:
    • biochemistry: 16,476 (rank: 47 out of 17,448)
    • biophysics: 4,785 (rank: 223 out of 15,712)
    • cancer biology: 329 (rank: 15,563 (tie) out of 26,234)
    • cell biology: 1,215 (rank: 3,783 (tie) out of 28,321)
    • genetics: 2,857 (rank: 5,480 (tie) out of 35,227)
    • microbiology: 5,409 (rank: 1,211 out of 42,823)
    • molecular biology: 1,619 (rank: 1,820 (tie) out of 19,756)

Downloads per author, site-wide

Preprints

CRISPR-Cas12a target binding unleashes single-stranded DNase activity

biochemistry more details view paper
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    • In biochemistry: 16 out of 2,969
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    • Site-wide: 3,764 out of 88,882
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    • Site-wide: 7,694 out of 88,882

Enhanced proofreading governs CRISPR-Cas9 targeting accuracy

biochemistry more details view paper
  • Downloaded 4,749 times
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    • In biochemistry: 18 out of 2,969
  • Year to date:
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  • Since beginning of last month:
    • Site-wide: 49,925 out of 88,882

Clades of huge phage from across Earth's ecosystems

microbiology more details view paper
  • Downloaded 4,182 times
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    • Site-wide: 1,038 out of 88,882
    • In microbiology: 105 out of 7,648
  • Year to date:
    • Site-wide: 2,595 out of 88,882
  • Since beginning of last month:
    • Site-wide: 20,928 out of 88,882

CRISPR-Cpf1 mediates efficient homology-directed repair and temperature-controlled genome editing

genetics more details view paper
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    • In genetics: 154 out of 4,604
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    • Site-wide: 23,277 out of 88,882
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    • Site-wide: 34,824 out of 88,882

RNA binding and HEPN nuclease activation are decoupled in CRISPR-Cas13a

biochemistry more details view paper
  • Downloaded 2,142 times
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    • Site-wide: 3,250 out of 88,882
    • In biochemistry: 77 out of 2,969
  • Year to date:
    • Site-wide: 14,791 out of 88,882
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    • Site-wide: 38,106 out of 88,882

Molecular mechanism of off-target effects in CRISPR-Cas9

biophysics more details view paper
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    • In biophysics: 118 out of 3,871
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    • Site-wide: 39,958 out of 88,882

Massively parallel kinetic profiling of natural and engineered CRISPR nucleases

molecular biology more details view paper
  • Downloaded 1,619 times
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    • Site-wide: 5,143 out of 88,882
    • In molecular biology: 167 out of 3,005
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    • Site-wide: 4,268 out of 88,882
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    • Site-wide: 9,895 out of 88,882

Programmable RNA recognition using a CRISPR-associated Argonaute

biochemistry more details view paper
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    • In biochemistry: 137 out of 2,969
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    • Site-wide: 23,275 out of 88,882

A Conformational Checkpoint Between DNA Binding And Cleavage By CRISPR-Cas9

biophysics more details view paper
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    • Site-wide: 5,762 out of 88,882
    • In biophysics: 164 out of 3,871
  • Year to date:
    • Site-wide: 61,851 out of 88,882
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    • Site-wide: 39,764 out of 88,882

Temperature-responsive competitive inhibition of CRISPR-Cas9

biochemistry more details view paper
  • Downloaded 1,498 times
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    • Site-wide: 5,859 out of 88,882
    • In biochemistry: 141 out of 2,969
  • Year to date:
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  • Since beginning of last month:
    • Site-wide: 83,296 out of 88,882

Real-time observation of DNA recognition and rejection by the RNA-guided endonuclease Cas9

biophysics more details view paper
  • Downloaded 1,469 times
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    • Site-wide: 6,051 out of 88,882
    • In biophysics: 171 out of 3,871
  • Year to date:
    • Site-wide: 68,978 out of 88,882
  • Since beginning of last month:
    • Site-wide: 70,987 out of 88,882

Widespread translational remodeling during human neuronal differentiation

cell biology more details view paper
  • Downloaded 1,215 times
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    • Site-wide: 8,283 out of 88,882
    • In cell biology: 292 out of 4,555
  • Year to date:
    • Site-wide: 58,108 out of 88,882
  • Since beginning of last month:
    • Site-wide: 55,528 out of 88,882

CRISPR-Cas12a exploits R-loop asymmetry to form double-strand breaks

biochemistry more details view paper
  • Downloaded 998 times
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    • Site-wide: 11,457 out of 88,882
    • In biochemistry: 255 out of 2,969
  • Year to date:
    • Site-wide: 1,390 out of 88,882
  • Since beginning of last month:
    • Site-wide: 8,334 out of 88,882

Candidate Phyla Radiation Roizmanbacteria from hot springs have novel, unexpectedly abundant, and potentially alternatively functioning CRISPR-Cas systems

microbiology more details view paper
  • Downloaded 780 times
  • Download rankings, all-time:
    • Site-wide: 16,792 out of 88,882
    • In microbiology: 1,014 out of 7,648
  • Year to date:
    • Site-wide: 41,742 out of 88,882
  • Since beginning of last month:
    • Site-wide: 19,440 out of 88,882

Potent CRISPR-Cas9 inhibitors from Staphylococcus genomes

biochemistry more details view paper
  • Downloaded 627 times
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    • Site-wide: 23,190 out of 88,882
    • In biochemistry: 609 out of 2,969
  • Year to date:
    • Site-wide: 17,061 out of 88,882
  • Since beginning of last month:
    • Site-wide: 69,088 out of 88,882

Huge and variable diversity of episymbiotic CPR bacteria and DPANN archaea in groundwater ecosystems

microbiology more details view paper
  • Downloaded 447 times
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    • Site-wide: 35,602 out of 88,882
    • In microbiology: 2,409 out of 7,648
  • Year to date:
    • Site-wide: 4,636 out of 88,882
  • Since beginning of last month:
    • Site-wide: 2,927 out of 88,882

Cancer-specific loss of TERT activation sensitizes glioblastoma to DNA damage

cancer biology more details view paper
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    • Site-wide: 48,832 out of 88,882
    • In cancer biology: 1,540 out of 3,128
  • Year to date:
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  • Since beginning of last month:
    • Site-wide: 14,313 out of 88,882

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