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Author: Jennifer Doudna

  • ORCiD: http://orcid.org/0000-0001-9161-999X
  • Most recently observed institution: Department of Molecular and Cell Biology, University of California Berkeley, Berkeley, CA 94720, USA; Department of Chemistry, University of California Berkeley, Berkeley, CA, 94720, USA; Innovative Genomics Initiative, University of California Berkeley,

Rankings

  • All-time downloads: 34,285 (rank: 1,310 out of 404,161)
  • Categories:
    • biochemistry: 19,809 (rank: 39 out of 19,151)
    • biophysics: 4,833 (rank: 247 out of 16,811)
    • cancer biology: 398 (rank: 14,548 (tie) out of 28,183)
    • microbiology: 3,471 (rank: 2,490 out of 46,811)
    • synthetic biology: 2,454 (rank: 414 (tie) out of 4,220)
    • systems biology: 3,320 (rank: 797 (tie) out of 11,761)

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Preprints

CRISPR-Cas12a target binding unleashes single-stranded DNase activity

biochemistry more details view paper
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    • Site-wide: 4,158 out of 94,912
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    • Site-wide: 10,034 out of 94,912

Enhanced proofreading governs CRISPR-Cas9 targeting accuracy

biochemistry more details view paper
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    • In biochemistry: 22 out of 3,211
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    • Site-wide: 51,633 out of 94,912

A compound that directly and selectively stalls PCSK9 translation

systems biology more details view paper
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    • In systems biology: 37 out of 2,425
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Controlling CRISPR-Cas9 with ligand-activated and ligand-deactivated sgRNAs

synthetic biology more details view paper
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    • In synthetic biology: 46 out of 885
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    • Site-wide: 42,360 out of 94,912

RNA binding and HEPN nuclease activation are decoupled in CRISPR-Cas13a

biochemistry more details view paper
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    • In biochemistry: 87 out of 3,211
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Targeted Genome Editing of Bacteria Within Microbial Communities

microbiology more details view paper
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Disabling Cas9 by an anti-CRISPR DNA mimic

biochemistry more details view paper
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    • In biochemistry: 106 out of 3,211
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High-throughput biochemical profiling reveals Cas9 off-target binding and unbinding heterogeneity

biochemistry more details view paper
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Molecular mechanism of off-target effects in CRISPR-Cas9

biophysics more details view paper
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    • In biophysics: 122 out of 4,144
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A Conformational Checkpoint Between DNA Binding And Cleavage By CRISPR-Cas9

biophysics more details view paper
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    • In biophysics: 174 out of 4,144
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    • Site-wide: 84,559 out of 94,912

Temperature-responsive competitive inhibition of CRISPR-Cas9

biochemistry more details view paper
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    • In biochemistry: 152 out of 3,211
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    • Site-wide: 40,458 out of 94,912

Real-time observation of DNA recognition and rejection by the RNA-guided endonuclease Cas9

biophysics more details view paper
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    • In biophysics: 185 out of 4,144
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    • Site-wide: 76,041 out of 94,912

CRISPR-Cas12a exploits R-loop asymmetry to form double-strand breaks

biochemistry more details view paper
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    • In biochemistry: 275 out of 3,211
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    • Site-wide: 1,828 out of 94,912
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    • Site-wide: 20,391 out of 94,912

Machine Learning Predicts New Anti-CRISPR Proteins

biochemistry more details view paper
  • Downloaded 882 times
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    • In biochemistry: 372 out of 3,211
  • Year to date:
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    • Site-wide: 33,000 out of 94,912

Candidate Phyla Radiation Roizmanbacteria from hot springs have novel, unexpectedly abundant, and potentially alternatively functioning CRISPR-Cas systems

microbiology more details view paper
  • Downloaded 793 times
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    • In microbiology: 1,118 out of 8,320
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    • Site-wide: 46,818 out of 94,912
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    • Site-wide: 50,774 out of 94,912

Potent CRISPR-Cas9 inhibitors from Staphylococcus genomes

biochemistry more details view paper
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    • In biochemistry: 659 out of 3,211
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Huge and variable diversity of episymbiotic CPR bacteria and DPANN archaea in groundwater ecosystems

microbiology more details view paper
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Cancer-specific loss of TERT activation sensitizes glioblastoma to DNA damage

cancer biology more details view paper
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    • In cancer biology: 1,382 out of 3,367
  • Year to date:
    • Site-wide: 7,734 out of 94,912
  • Since beginning of last month:
    • Site-wide: 14,873 out of 94,912

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