Author: Yan Li

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Preprints

Correlation between universal BCG vaccination policy and reduced morbidity and mortality for COVID-19: an epidemiological study

• Downloaded 355,252 times
• Download rankings, all-time:
  • Site-wide: 6
  • In epidemiology: 1
• Year to date:
  • Site-wide: 351
• Since beginning of last month:
  • Site-wide: 1,358

First 12 patients with coronavirus disease 2019 (COVID-19) in the United States

• Downloaded 105,632 times
• Download rankings, all-time:
  • Site-wide: 44
  • In public and global health: 2
• Year to date:
  • Site-wide: 1,068
• Since beginning of last month:
  • Site-wide: 11,093

Time-varying transmission dynamics of Novel Coronavirus Pneumonia in China

• Downloaded 42,459 times
• Download rankings, all-time:
  • Site-wide: 157
  • In systems biology: 2
• Year to date:
  • Site-wide: 1,684
• Since beginning of last month:
  • Site-wide: 7,914

Isolation and characterization of SARS-CoV-2 from the first US COVID-19 patient

• Downloaded 26,993 times
• Download rankings, all-time:
  • Site-wide: 273
  • In microbiology: 25
• Year to date:
  • Site-wide: 442
• Since beginning of last month:
  • Site-wide: 1,964

Clinical diagnosis of 8274 samples with 2019-novel coronavirus in Wuhan

• Downloaded 21,398 times
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  • Site-wide: 364
  • In infectious diseases: 135
• Year to date:
  • Site-wide: 5,586
• Since beginning of last month:
  • Site-wide: 8,156

Viral infection and Transmission in a large well-traced outbreak caused by the Delta SARS-CoV-2 variant

• Downloaded 12,033 times
• Download rankings, all-time:
  • Site-wide: 743
  • In epidemiology: 110
• Year to date:
  • Site-wide: 148
• Since beginning of last month:
  • Site-wide: 109

Single Molecule Sequencing Of M13 Virus Genome Without Amplification

• Downloaded 7,560 times
• Download rankings, all-time:
  • Site-wide: 1,349
  • In genomics: 111
• Year to date:
  • Site-wide: 115,324
• Since beginning of last month:
  • Site-wide: None

Prevention and Attenuation of COVID-19 by BNT162b2 and mRNA-1273 Vaccines

• Downloaded 7,374 times
• Download rankings, all-time:
  • Site-wide: 1,397
  • In epidemiology: 172
• Year to date:
  • Site-wide: 266
• Since beginning of last month:
  • Site-wide: 4,844

Therapeutic Drugs Targeting 2019-nCoV Main Protease by High-Throughput Screening

• Downloaded 6,889 times
• Download rankings, all-time:
  • Site-wide: 1,502
  • In pharmacology and toxicology: 8
• Year to date:
  • Site-wide: 12,353
• Since beginning of last month:
  • Site-wide: 30,219

A Genomic Survey of SARS-CoV-2 Reveals Multiple Introductions into Northern California without a Predominant Lineage

• Downloaded 6,829 times
• Download rankings, all-time:
  • Site-wide: 1,523
  • In infectious diseases: 415
• Year to date:
  • Site-wide: 6,935
• Since beginning of last month:
  • Site-wide: 46,833

Rapid adaptation of SARS-CoV-2 in BALB/c mice: Novel mouse model for vaccine efficacy

• Downloaded 6,511 times
• Download rankings, all-time:
  • Site-wide: 1,624
  • In microbiology: 142
• Year to date:
  • Site-wide: 2,519
• Since beginning of last month:
  • Site-wide: 610

Nanopore target sequencing for accurate and comprehensive detection of SARS-CoV-2 and other respiratory viruses

• Downloaded 5,951 times
• Download rankings, all-time:
  • Site-wide: 1,854
  • In infectious diseases: 475
• Year to date:
  • Site-wide: 2,143
• Since beginning of last month:
  • Site-wide: 16,626

Easy Hi-C: A simple efficient protocol for 3D genome mapping in small cell populations

• Downloaded 5,075 times
• Download rankings, all-time:
  • Site-wide: 2,306
  • In genomics: 216
• Year to date:
  • Site-wide: 8,622
• Since beginning of last month:
  • Site-wide: 29,565

Safety and immunogenicity of a recombinant tandem-repeat dimeric RBD protein vaccine against COVID-19 in adults: pooled analysis of two randomized, double-blind, placebo-controlled, phase 1 and 2 trials

• Downloaded 4,285 times
• Download rankings, all-time:
  • Site-wide: 2,937
  • In infectious diseases: 639
• Year to date:
  • Site-wide: 562
• Since beginning of last month:
  • Site-wide: 11,012

The production of antibodies for SARS-CoV-2 and its clinical implication

• Downloaded 3,995 times
• Download rankings, all-time:
  • Site-wide: 3,240
  • In allergy and immunology: 22
• Year to date:
  • Site-wide: 7,205
• Since beginning of last month:
  • Site-wide: 16,777

Immunodepletion with Hypoxemia: A Potential High Risk Subtype of Coronavirus Disease 2019

• Downloaded 2,991 times
• Download rankings, all-time:
  • Site-wide: 4,842
  • In infectious diseases: 888
• Year to date:
  • Site-wide: 11,723
• Since beginning of last month:
  • Site-wide: 46,674

Resequencing the Escherichia coli genome by GenoCare single molecule sequencing platform

• Downloaded 2,858 times
• Download rankings, all-time:
  • Site-wide: 5,168
  • In genomics: 524
• Year to date:
  • Site-wide: 111,656
• Since beginning of last month:
  • Site-wide: None

An in-depth investigation of the safety and immunogenicity of an inactivated SARS-CoV-2 vaccine

• Downloaded 2,680 times
• Download rankings, all-time:
  • Site-wide: 5,677
  • In public and global health: 164
• Year to date:
  • Site-wide: 2,272
• Since beginning of last month:
  • Site-wide: 18,455

Study on the expression levels of antibodies against SARS-CoV-2 at different period of disease and its related factors in 192 cases of COVID-19 patients

• Downloaded 2,512 times
• Download rankings, all-time:
  • Site-wide: 6,253
  • In infectious diseases: 1,032
• Year to date:
  • Site-wide: 1,972
• Since beginning of last month:
  • Site-wide: 13,032

Mapping a Pandemic: SARS-CoV-2 Seropositivity in the United States

• Downloaded 2,509 times
• Download rankings, all-time:
  • Site-wide: 6,271
  • In infectious diseases: 1,034
• Year to date:
  • Site-wide: 914
• Since beginning of last month:
  • Site-wide: None

SARS-CoV-2 infection does not significantly cause acute renal injury: an analysis of 116 hospitalized patients with COVID-19 in a single hospital, Wuhan, China

• Downloaded 2,396 times
• Download rankings, all-time:
  • Site-wide: 6,727
  • In infectious diseases: 1,069
• Year to date:
  • Site-wide: 43,330
• Since beginning of last month:
  • Site-wide: 26,155

LRRK2 mediates tubulation and vesicle sorting from membrane damaged lysosomes

• Downloaded 2,049 times
• Download rankings, all-time:
  • Site-wide: 8,413
  • In cell biology: 183
• Year to date:
  • Site-wide: 49,650
• Since beginning of last month:
  • Site-wide: 15,424

Multi-organ Proteomic Landscape of COVID-19 Autopsies

• Downloaded 2,015 times
• Download rankings, all-time:
  • Site-wide: 8,630
  • In infectious diseases: 1,250
• Year to date:
  • Site-wide: 5,995
• Since beginning of last month:
  • Site-wide: 42,486

Rapid, sensitive, full genome sequencing of Severe Acute Respiratory Syndrome Virus Coronavirus 2 (SARS-CoV-2)

• Downloaded 1,876 times
• Download rankings, all-time:
  • Site-wide: 9,626
  • In genomics: 983
• Year to date:
  • Site-wide: 13,522
• Since beginning of last month:
  • Site-wide: 68,466

Evolutionary history of the brown rat: out of southern East Asia and selection

• Downloaded 1,799 times
• Download rankings, all-time:
  • Site-wide: 10,229
  • In evolutionary biology: 294
• Year to date:
  • Site-wide: 12,207
• Since beginning of last month:
  • Site-wide: 31,325

Genome sequence and analysis of the eggplant (Solanum melongena L.)

• Downloaded 1,780 times
• Download rankings, all-time:
  • Site-wide: 10,399
  • In genomics: 1,072
• Year to date:
  • Site-wide: 18,995
• Since beginning of last month:
  • Site-wide: 91,605

Discovery and Development of Human SARS-CoV-2 Neutralizing Antibodies using an Unbiased Phage Display Library Approach

• Downloaded 1,536 times
• Download rankings, all-time:
  • Site-wide: 12,832
  • In microbiology: 755
• Year to date:
  • Site-wide: 19,854
• Since beginning of last month:
  • Site-wide: 110,437

Robust Hi-C chromatin loop maps in human neurogenesis and brain tissues at high-resolution

• Downloaded 1,416 times
• Download rankings, all-time:
  • Site-wide: 14,547
  • In genomics: 1,476
• Year to date:
  • Site-wide: 18,855
• Since beginning of last month:
  • Site-wide: 11,864

Developmental trajectory of pre-hematopoietic stem cell formation from endothelium

• Downloaded 1,343 times
• Download rankings, all-time:
  • Site-wide: 15,781
  • In developmental biology: 243
• Year to date:
  • Site-wide: 16,585
• Since beginning of last month:
  • Site-wide: 61,044

Proteomics Uncovers Immunosuppression in COVID-19 Patients with Long Disease Course

• Downloaded 1,294 times
• Download rankings, all-time:
  • Site-wide: 16,722
  • In respiratory medicine: 59
• Year to date:
  • Site-wide: 21,496
• Since beginning of last month:
  • Site-wide: 19,190

Efficacy and Safety of Leflunomide for Refractory COVID-19: An Open-label Controlled Study

• Downloaded 1,271 times
• Download rankings, all-time:
  • Site-wide: 17,151
  • In infectious diseases: 1,770
• Year to date:
  • Site-wide: 21,113
• Since beginning of last month:
  • Site-wide: 37,450

ACE2 expression in human dorsal root ganglion sensory neurons: implications for SARS-CoV-2 virus-induced neurological effects

• Downloaded 1,215 times
• Download rankings, all-time:
  • Site-wide: 18,335
  • In neuroscience: 2,233
• Year to date:
  • Site-wide: 13,112
• Since beginning of last month:
  • Site-wide: 30,646

Building a sequence map of the pig pan-genome from multiple de novo assemblies and Hi-C data

• Downloaded 1,118 times
• Download rankings, all-time:
  • Site-wide: 20,724
  • In genomics: 1,985
• Year to date:
  • Site-wide: 47,253
• Since beginning of last month:
  • Site-wide: None

Exploring genes of rectal cancer for new treatments based on protein interaction network

• Downloaded 1,099 times
• Download rankings, all-time:
  • Site-wide: 21,246
  • In cancer biology: 500
• Year to date:
  • Site-wide: 114,729
• Since beginning of last month:
  • Site-wide: 64,086

Genomic and phylogenetic analysis of Salmonella Typhimurium and its monophasic variants responsible for invasive endemic infections in Colombia

• Downloaded 1,056 times
• Download rankings, all-time:
  • Site-wide: 22,556
  • In genomics: 2,139
• Year to date:
  • Site-wide: 35,270
• Since beginning of last month:
  • Site-wide: None

Neuroendocrine Modulation Sustains the C. elegans Forward Motor State

• Downloaded 1,040 times
• Download rankings, all-time:
  • Site-wide: 23,062
  • In neuroscience: 2,872
• Year to date:
  • Site-wide: 120,152
• Since beginning of last month:
  • Site-wide: 75,072

Transmission Dynamics and Control Methodology of COVID-19: a Modeling Study

• Downloaded 1,026 times
• Download rankings, all-time:
  • Site-wide: 23,484
  • In epidemiology: 1,383
• Year to date:
  • Site-wide: 49,741
• Since beginning of last month:
  • Site-wide: 104,738

Projected COVID-19 epidemic in the United States in the context of the effectiveness of a potential vaccine and implications for social distancing and face mask use

• Downloaded 1,012 times
• Download rankings, all-time:
  • Site-wide: 23,960
  • In infectious diseases: 2,062
• Year to date:
  • Site-wide: 12,051
• Since beginning of last month:
  • Site-wide: 12,909

Mutations in Auxilin cause parkinsonism via impaired clathrin-mediated trafficking at the Golgi apparatus and synapse

• Downloaded 938 times
• Download rankings, all-time:
  • Site-wide: 26,821
  • In neuroscience: 3,455
• Year to date:
  • Site-wide: 40,504
• Since beginning of last month:
  • Site-wide: None

A valid protective immune response elicited in rhesus macaques by an inactivated vaccine is capable of defending against SARS-CoV-2 infection

• Downloaded 841 times
• Download rankings, all-time:
  • Site-wide: 31,207
  • In immunology: 969
• Year to date:
  • Site-wide: 37,545
• Since beginning of last month:
  • Site-wide: 18,663

A novel network control model for identifying personalized driver genes in cancer

• Downloaded 834 times
• Download rankings, all-time:
  • Site-wide: 31,571
  • In systems biology: 656
• Year to date:
  • Site-wide: 90,266
• Since beginning of last month:
  • Site-wide: 62,303

LCA robustly reveals subtle diversity in large-scale single-cell RNA-seq data

• Downloaded 811 times
• Download rankings, all-time:
  • Site-wide: 32,829
  • In bioinformatics: 3,651
• Year to date:
  • Site-wide: 121,151
• Since beginning of last month:
  • Site-wide: 71,387

Methylglyoxal modification of TrkB promotes synaptic plasticity and enhances resilience to chronic stress

• Downloaded 766 times
• Download rankings, all-time:
  • Site-wide: 35,555
  • In neuroscience: 4,816
• Year to date:
  • Site-wide: 56,742
• Since beginning of last month:
  • Site-wide: None

The Foundational data initiative for Parkinsons disease (FOUNDIN-PD): enabling efficient translation from genetic maps to mechanism

• Downloaded 755 times
• Download rankings, all-time:
  • Site-wide: 36,262
  • In genomics: 3,053
• Year to date:
  • Site-wide: 4,658
• Since beginning of last month:
  • Site-wide: 10,870

Convergent genomic signatures of high altitude adaptation among domestic mammals

• Downloaded 750 times
• Download rankings, all-time:
  • Site-wide: 36,636
  • In evolutionary biology: 1,696
• Year to date:
  • Site-wide: 73,483
• Since beginning of last month:
  • Site-wide: 89,042

Recombinant Fc-fusion vaccine of RBD induced protection against SARS-CoV-2 in non-human primate and mice

• Downloaded 733 times
• Download rankings, all-time:
  • Site-wide: 37,811
  • In immunology: 1,167
• Year to date:
  • Site-wide: 11,780
• Since beginning of last month:
  • Site-wide: 6,631

Separate Fever Clinics Prevent the Spread of COVID-19 and Offload Emergency Resources: Analysis from a large tertiary hospital in China

• Downloaded 731 times
• Download rankings, all-time:
  • Site-wide: 37,931
  • In infectious diseases: 2,637
• Year to date:
  • Site-wide: 64,129
• Since beginning of last month:
  • Site-wide: 42,189

Transcriptional regulatory network controlling the ontogeny of hematopoietic stem cells

• Downloaded 717 times
• Download rankings, all-time:
  • Site-wide: 38,952
  • In developmental biology: 818
• Year to date:
  • Site-wide: 73,861
• Since beginning of last month:
  • Site-wide: 92,657

Nociceptor translational profiling reveals the RagA-mTORC1 network as a critical generator of neuropathic pain

• Downloaded 711 times
• Download rankings, all-time:
  • Site-wide: 39,436
  • In neuroscience: 5,447
• Year to date:
  • Site-wide: 113,243
• Since beginning of last month:
  • Site-wide: 34,981

Inhibition of amyloid formation of the Nucleoprotein of SARS-CoV-2

• Downloaded 701 times
• Download rankings, all-time:
  • Site-wide: 40,110
  • In biochemistry: 993
• Year to date:
  • Site-wide: 5,191
• Since beginning of last month:
  • Site-wide: 19,638

TWO-SIGMA: a novel TWO-component SInGle cell Model-based Association method for single-cell RNA-seq data

• Downloaded 661 times
• Download rankings, all-time:
  • Site-wide: 43,353
  • In genomics: 3,481
• Year to date:
  • Site-wide: 48,364
• Since beginning of last month:
  • Site-wide: 88,021

Pathway-Structured Predictive Model for Cancer Survival Prediction: A Two-Stage Approach

• Downloaded 643 times
• Download rankings, all-time:
  • Site-wide: 44,932
  • In bioinformatics: 4,735
• Year to date:
  • Site-wide: 144,707
• Since beginning of last month:
  • Site-wide: 72,046

A cell-free platform based on nisin biosynthesis for discovering novel lanthipeptides and guiding their overproduction in vivo

• Downloaded 620 times
• Download rankings, all-time:
  • Site-wide: 47,035
  • In synthetic biology: 579
• Year to date:
  • Site-wide: 64,173
• Since beginning of last month:
  • Site-wide: None

Wiring logic of the early rodent olfactory system revealed by high-throughput sequencing of single neuron projections

• Downloaded 617 times
• Download rankings, all-time:
  • Site-wide: 47,297
  • In neuroscience: 6,737
• Year to date:
  • Site-wide: 6,214
• Since beginning of last month:
  • Site-wide: 53,666

Manipulation of Seedling Traits with Pulsed Light in Closed Controlled Environments

• Downloaded 614 times
• Download rankings, all-time:
  • Site-wide: 47,662
  • In plant biology: 1,058
• Year to date:
  • Site-wide: 43,658
• Since beginning of last month:
  • Site-wide: 86,865

A transferrable and interpretable multiple instance learning model for microsatellite instability prediction based on histopathology images

• Downloaded 609 times
• Download rankings, all-time:
  • Site-wide: 48,063
  • In bioengineering: 893
• Year to date:
  • Site-wide: 42,371
• Since beginning of last month:
  • Site-wide: 32,831

Transmission dynamics and epidemiological characteristics of Delta variant infections in China

• Downloaded 590 times
• Download rankings, all-time:
  • Site-wide: 50,027
  • In epidemiology: 2,336
• Year to date:
  • Site-wide: 6,692
• Since beginning of last month:
  • Site-wide: 52

Genome structure and evolution of Antirrhnum majus L.

• Downloaded 584 times
• Download rankings, all-time:
  • Site-wide: 50,761
  • In genomics: 3,896
• Year to date:
  • Site-wide: 124,427
• Since beginning of last month:
  • Site-wide: 60,263

Fine-tuning of ABA responses by the protein kinase WNK8

• Downloaded 583 times
• Download rankings, all-time:
  • Site-wide: 50,865
  • In plant biology: 1,169
• Year to date:
  • Site-wide: 92,938
• Since beginning of last month:
  • Site-wide: 56,902

The RhoGEF Cysts couples apical polarity proteins to Rho and myosin activity at adherens junctions

• Downloaded 545 times
• Download rankings, all-time:
  • Site-wide: 55,232
  • In cell biology: 2,397
• Year to date:
  • Site-wide: 143,224
• Since beginning of last month:
  • Site-wide: None

IRESbase: a Comprehensive Database of Experimentally Validated Internal Ribosome Entry Sites

• Downloaded 545 times
• Download rankings, all-time:
  • Site-wide: 55,216
  • In bioinformatics: 5,589
• Year to date:
  • Site-wide: 49,124
• Since beginning of last month:
  • Site-wide: 62,669

Sequential screening nominates the Parkinson's disease associated kinase LRRK2 as a regulator of Clathrin-mediated endocytosis

• Downloaded 522 times
• Download rankings, all-time:
  • Site-wide: 58,127
  • In molecular biology: 1,642
• Year to date:
  • Site-wide: 126,459
• Since beginning of last month:
  • Site-wide: 68,768

RNF5 Regulation of RBBP4 Defines Acute Myeloid Leukemia Growth and Susceptibility to Histone Deacetylase Inhibitors

• Downloaded 519 times
• Download rankings, all-time:
  • Site-wide: 58,507
  • In cancer biology: 1,654
• Year to date:
  • Site-wide: 20,819
• Since beginning of last month:
  • Site-wide: 8,509

CD55 regulates self-renewal and cisplatin resistance in endometrioid tumors

• Downloaded 490 times
• Download rankings, all-time:
  • Site-wide: 62,397
  • In cancer biology: 1,784
• Year to date:
  • Site-wide: 113,287
• Since beginning of last month:
  • Site-wide: None

PGC-1α coordinates with Bcl-2 to control cell cycle in U251 cells through reducing ROS

• Downloaded 482 times
• Download rankings, all-time:
  • Site-wide: 63,565
  • In biochemistry: 1,680
• Year to date:
  • Site-wide: 100,327
• Since beginning of last month:
  • Site-wide: 73,809

Associations between state-level healthcare access and COVID-19 case trajectories in the United States

• Downloaded 478 times
• Download rankings, all-time:
  • Site-wide: 64,203
  • In infectious diseases: 3,415
• Year to date:
  • Site-wide: 61,565
• Since beginning of last month:
  • Site-wide: 17,101

Lrfn2-mutant mice display suppressed synaptic plasticity and inhibitory synapse development and abnormal social communication and startle response

• Downloaded 477 times
• Download rankings, all-time:
  • Site-wide: 64,284
  • In neuroscience: 9,485
• Year to date:
  • Site-wide: 128,396
• Since beginning of last month:
  • Site-wide: None

Formation of tRNA wobble inosine in humans is perturbed by a millennia-old mutation linked to intellectual disability

• Downloaded 474 times
• Download rankings, all-time:
  • Site-wide: 64,807
  • In molecular biology: 1,836
• Year to date:
  • Site-wide: 128,112
• Since beginning of last month:
  • Site-wide: 29,822

Dosage effect of multiple genes accounts for multisystem disorder of myotonic dystrophy type 1

• Downloaded 467 times
• Download rankings, all-time:
  • Site-wide: 65,915
  • In genetics: 2,896
• Year to date:
  • Site-wide: 133,909
• Since beginning of last month:
  • Site-wide: None

Same-Day Simultaneous Diagnosis of Bacterial and Fungal Infections in Clinical Practice by Nanopore Targeted Sequencing

• Downloaded 460 times
• Download rankings, all-time:
  • Site-wide: 66,988
  • In infectious diseases: 3,478
• Year to date:
  • Site-wide: 65,624
• Since beginning of last month:
  • Site-wide: 42,404

Structural basis for polyglutamate chain initiation and elongation by TTLL family enzymes

• Downloaded 450 times
• Download rankings, all-time:
  • Site-wide: 68,432
  • In biochemistry: 1,833
• Year to date:
  • Site-wide: 47,415
• Since beginning of last month:
  • Site-wide: 25,539

Base pair editing of goat embryos: nonsense codon introgression into FGF5 to improve cashmere yield

• Downloaded 405 times
• Download rankings, all-time:
  • Site-wide: 76,053
  • In genetics: 3,316
• Year to date:
  • Site-wide: 128,695
• Since beginning of last month:
  • Site-wide: 72,926

Effects of New York's Executive Order on Face Mask Use on COVID-19 Infections and Mortality: A Modeling Study

• Downloaded 404 times
• Download rankings, all-time:
  • Site-wide: 76,158
  • In infectious diseases: 3,689
• Year to date:
  • Site-wide: 69,106
• Since beginning of last month:
  • Site-wide: 41,558

Genomic analyses provide insights into genetic architecture of three-way crossbred pigs

• Downloaded 365 times
• Download rankings, all-time:
  • Site-wide: 83,661
  • In genomics: 5,436
• Year to date:
  • Site-wide: 123,315
• Since beginning of last month:
  • Site-wide: None

Myt Transcription Factors prevent stress-response gene over-activation to enable postnatal pancreatic β cell proliferation and function

• Downloaded 355 times
• Download rankings, all-time:
  • Site-wide: 85,652
  • In developmental biology: 2,231
• Year to date:
  • Site-wide: 112,138
• Since beginning of last month:
  • Site-wide: 59,093

Energetic and structural features of SARS-CoV-2 N-protein co-assemblies with nucleic acids

• Downloaded 338 times
• Download rankings, all-time:
  • Site-wide: 89,031
  • In biophysics: 3,327
• Year to date:
  • Site-wide: 14,980
• Since beginning of last month:
  • Site-wide: 51,310

In-depth analysis reveals complex molecular etiology of idiopathic cerebral palsy

• Downloaded 335 times
• Download rankings, all-time:
  • Site-wide: 89,803
  • In genetics: 3,893
• Year to date:
  • Site-wide: 53,337
• Since beginning of last month:
  • Site-wide: 114,001

Time courses of COVID-19 infection and local variation in socioeconomic and health disparities in England

• Downloaded 332 times
• Download rankings, all-time:
  • Site-wide: 90,440
  • In public and global health: 1,146
• Year to date:
  • Site-wide: 97,229
• Since beginning of last month:
  • Site-wide: 47,700

Endogenous itaconate is not required for particulate matter-induced NRF2 expression or inflammatory response

• Downloaded 328 times
• Download rankings, all-time:
  • Site-wide: 91,409
  • In cell biology: 4,195
• Year to date:
  • Site-wide: 89,587
• Since beginning of last month:
  • Site-wide: None

Two Color Single Molecule Sequencing on GenoCare 1600 Platform to Facilitate Clinical Applications

• Downloaded 315 times
• Download rankings, all-time:
  • Site-wide: 94,317
  • In genetic and genomic medicine: 423
• Year to date:
  • Site-wide: 46,979
• Since beginning of last month:
  • Site-wide: 36,528

Bifunctional enzyme SpoT is involved in biofilm formation of Helicobacter pylori with multidrug resistance by upregulating efflux pump Hp1174 (gluP)

• Downloaded 308 times
• Download rankings, all-time:
  • Site-wide: 95,903
  • In microbiology: 6,850
• Year to date:
  • Site-wide: 140,780
• Since beginning of last month:
  • Site-wide: None

Exploring the impact of inoculum dose on host immunity and morbidity to inform model-based vaccine design

• Downloaded 308 times
• Download rankings, all-time:
  • Site-wide: 95,906
  • In systems biology: 2,172
• Year to date:
  • Site-wide: 113,029
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  • Site-wide: 79,592

The endoplasmic reticulum-resident protein TMEM-120/TMEM120A promotes fat storage in C. elegans and mammalian cells

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NOGEA: Network-Oriented Gene Entropy Approach for Dissecting Disease Comorbidity and Drug Repositioning

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  • Site-wide: 99,638
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The regulation of mammalian maternal-to-embryonic transition by Eukaryotic translation initiation factor 4E

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Trans-ethnic polygenic analysis supports genetic overlaps of lumbar disc degeneration with height, body mass index, and bone mineral density

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Genetic interaction between two unlinked loci underlies the loss of self-incompatibility in Arabidopsis lyrata

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Maximizing the Reusability of Gene Expression Data by Predicting Missing Metadata

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  • Site-wide: 108,763
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  • Site-wide: 90,585

Dietary disparities of urban immigrant schoolchildren in New York City: Results from a mixed-methods pilot study

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WBC-Profiler: an Unsupervised Feature Learning System for Leukocytes Characterization and Classification

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The collective influence of 1, 25-dihydroxyvitamin D3 with physiological fluid shear stress on osteoblasts

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  • Site-wide: 30,969

Abnormal nitration and S-sulfhydration of Sp1-CSE-H2S pathway contribute to the progress of HHcy

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A variant in SMOC2, inhibiting BMP signaling by competitively binding to BMPR1B, causes multiple epiphyseal dysplasia

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Clinical Significance of C4d Deposition in Renal Tissues from Patients with Primary Sj&oumlgren's Syndrome--A Preliminary Study

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Impact of Kuntai Capsules on LIF, IGF-1 and EGF Expression in the Implantation Window of Endometrium in Mice

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Projecting the impact of SARS-CoV-2 variants on the COVID-19 epidemic and social restoration in the United States: a mathematical modelling study

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  • Site-wide: 54,823

A study on the protective effects of CpG ODN-induced mucosal immunity against lung injury in a mouse ARDS model

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  • Site-wide: 82,202

INFIMA leverages multi-omics model organism data to identify effector genes of human GWAS variants

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  • Site-wide: 909

Fusobacterium nucleatum facilitates cetuximab resistance in colorectal cancer via the PI3K/AKT and JAK/STAT3 pathways

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Insights into the susceptibility of rice to a floral disease

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  • Site-wide: 51,790

Proteasome maturation factor UMP1 confers broad-spectrum disease resistance by modulating H2O2 accumulation in rice

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  • Site-wide: 114,631

Fucoidan but not 2'-Fucosyllactose could inhibit human norovirus replication in zebrafish larvae

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  • Site-wide: 50,206

MyD88-dependent TLR signaling oppositely regulates hematopoietic progenitor and stem cell formation in the embryo

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  • Site-wide: 55,484

Structure-based design of antisense oligonucleotides that inhibit SARS-CoV-2 replication

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  • Site-wide: 1,593

Recurrent micropollutant exposure leads to divergent degradation abilities and community succession in a freshwater microbiome

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  • Site-wide: 29,135