Author: Yan Li

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Preprints

Prevention and Attenuation of COVID-19 by BNT162b2 and mRNA-1273 Vaccines

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Correlation between universal BCG vaccination policy and reduced morbidity and mortality for COVID-19: an epidemiological study

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First 12 patients with coronavirus disease 2019 (COVID-19) in the United States

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Time-varying transmission dynamics of Novel Coronavirus Pneumonia in China

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Isolation and characterization of SARS-CoV-2 from the first US COVID-19 patient

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Clinical diagnosis of 8274 samples with 2019-novel coronavirus in Wuhan

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Single Molecule Sequencing Of M13 Virus Genome Without Amplification

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Therapeutic Drugs Targeting 2019-nCoV Main Protease by High-Throughput Screening

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A Genomic Survey of SARS-CoV-2 Reveals Multiple Introductions into Northern California without a Predominant Lineage

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Rapid adaptation of SARS-CoV-2 in BALB/c mice: Novel mouse model for vaccine efficacy

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Easy Hi-C: A simple efficient protocol for 3D genome mapping in small cell populations

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Nanopore target sequencing for accurate and comprehensive detection of SARS-CoV-2 and other respiratory viruses

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  • Site-wide: 23,601

Safety and immunogenicity of a recombinant tandem-repeat dimeric RBD protein vaccine against COVID-19 in adults: pooled analysis of two randomized, double-blind, placebo-controlled, phase 1 and 2 trials

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The production of antibodies for SARS-CoV-2 and its clinical implication

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Immunodepletion with Hypoxemia: A Potential High Risk Subtype of Coronavirus Disease 2019

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Resequencing the Escherichia coli genome by GenoCare single molecule sequencing platform

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An in-depth investigation of the safety and immunogenicity of an inactivated SARS-CoV-2 vaccine

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Mapping a Pandemic: SARS-CoV-2 Seropositivity in the United States

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SARS-CoV-2 infection does not significantly cause acute renal injury: an analysis of 116 hospitalized patients with COVID-19 in a single hospital, Wuhan, China

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Study on the expression levels of antibodies against SARS-CoV-2 at different period of disease and its related factors in 192 cases of COVID-19 patients

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  • Site-wide: 1,820
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LRRK2 mediates tubulation and vesicle sorting from membrane damaged lysosomes

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Multi-organ Proteomic Landscape of COVID-19 Autopsies

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Rapid, sensitive, full genome sequencing of Severe Acute Respiratory Syndrome Virus Coronavirus 2 (SARS-CoV-2)

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  • Site-wide: 9,451
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Evolutionary history of the brown rat: out of southern East Asia and selection

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Genome sequence and analysis of the eggplant (Solanum melongena L.)

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Discovery and Development of Human SARS-CoV-2 Neutralizing Antibodies using an Unbiased Phage Display Library Approach

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  • Site-wide: 12,576
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Robust Hi-C chromatin loop maps in human neurogenesis and brain tissues at high-resolution

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  • Site-wide: 14,270
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Developmental trajectory of pre-hematopoietic stem cell formation from endothelium

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  • Site-wide: 16,194
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  • Site-wide: 17,177
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  • Site-wide: 16,538

Proteomics Uncovers Immunosuppression in COVID-19 Patients with Long Disease Course

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  • Site-wide: 16,605
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  • Site-wide: 15,588

Efficacy and Safety of Leflunomide for Refractory COVID-19: An Open-label Controlled Study

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  • Site-wide: 16,822
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  • Site-wide: 18,187
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  • Site-wide: 21,399

ACE2 expression in human dorsal root ganglion sensory neurons: implications for SARS-CoV-2 virus-induced neurological effects

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  • Site-wide: 18,921
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  • Site-wide: 11,724

Exploring genes of rectal cancer for new treatments based on protein interaction network

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  • Site-wide: 70,287

Building a sequence map of the pig pan-genome from multiple de novo assemblies and Hi-C data

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Neuroendocrine Modulation Sustains the C. elegans Forward Motor State

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  • Site-wide: 100,196

Genomic and phylogenetic analysis of Salmonella Typhimurium and its monophasic variants responsible for invasive endemic infections in Colombia

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Transmission Dynamics and Control Methodology of COVID-19: a Modeling Study

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  • Site-wide: 23,333
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Projected COVID-19 epidemic in the United States in the context of the effectiveness of a potential vaccine and implications for social distancing and face mask use

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  • Site-wide: 25,402
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Mutations in Auxilin cause parkinsonism via impaired clathrin-mediated trafficking at the Golgi apparatus and synapse

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A novel network control model for identifying personalized driver genes in cancer

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  • Site-wide: 30,440
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A valid protective immune response elicited in rhesus macaques by an inactivated vaccine is capable of defending against SARS-CoV-2 infection

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  • Site-wide: 31,210
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LCA robustly reveals subtle diversity in large-scale single-cell RNA-seq data

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Methylglyoxal modification of TrkB promotes synaptic plasticity and enhances resilience to chronic stress

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Convergent genomic signatures of high altitude adaptation among domestic mammals

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Transcriptional regulatory network controlling the ontogeny of hematopoietic stem cells

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Separate Fever Clinics Prevent the Spread of COVID-19 and Offload Emergency Resources: Analysis from a large tertiary hospital in China

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Nociceptor translational profiling reveals the RagA-mTORC1 network as a critical generator of neuropathic pain

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TWO-SIGMA: a novel TWO-component SInGle cell Model-based Association method for single-cell RNA-seq data

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Recombinant Fc-fusion vaccine of RBD induced protection against SARS-CoV-2 in non-human primate and mice

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Pathway-Structured Predictive Model for Cancer Survival Prediction: A Two-Stage Approach

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A cell-free platform based on nisin biosynthesis for discovering novel lanthipeptides and guiding their overproduction in vivo

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A transferrable and interpretable multiple instance learning model for microsatellite instability prediction based on histopathology images

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Manipulation of Seedling Traits with Pulsed Light in Closed Controlled Environments

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  • Site-wide: 60,307

Inhibition of amyloid formation of the Nucleoprotein of SARS-CoV-2

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Genome structure and evolution of Antirrhnum majus L.

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Fine-tuning of ABA responses by the protein kinase WNK8

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The RhoGEF Cysts couples apical polarity proteins to Rho and myosin activity at adherens junctions

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IRESbase: a Comprehensive Database of Experimentally Validated Internal Ribosome Entry Sites

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The Foundational data initiative for Parkinsons disease (FOUNDIN-PD): enabling efficient translation from genetic maps to mechanism

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Sequential screening nominates the Parkinson's disease associated kinase LRRK2 as a regulator of Clathrin-mediated endocytosis

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CD55 regulates self-renewal and cisplatin resistance in endometrioid tumors

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PGC-1α coordinates with Bcl-2 to control cell cycle in U251 cells through reducing ROS

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Lrfn2-mutant mice display suppressed synaptic plasticity and inhibitory synapse development and abnormal social communication and startle response

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RNF5 Regulation of RBBP4 Defines Acute Myeloid Leukemia Growth and Susceptibility to Histone Deacetylase Inhibitors

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Formation of tRNA wobble inosine in humans is perturbed by a millennia-old mutation linked to intellectual disability

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Dosage effect of multiple genes accounts for multisystem disorder of myotonic dystrophy type 1

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Wiring logic of the early rodent olfactory system revealed by high-throughput sequencing of single neuron projections

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Same-Day Simultaneous Diagnosis of Bacterial and Fungal Infections in Clinical Practice by Nanopore Targeted Sequencing

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Associations between state-level healthcare access and COVID-19 case trajectories in the United States

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Structural basis for polyglutamate chain initiation and elongation by TTLL family enzymes

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Base pair editing of goat embryos: nonsense codon introgression into FGF5 to improve cashmere yield

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Effects of New York's Executive Order on Face Mask Use on COVID-19 Infections and Mortality: A Modeling Study

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Genomic analyses provide insights into genetic architecture of three-way crossbred pigs

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Myt Transcription Factors prevent stress-response gene over-activation to enable postnatal pancreatic β cell proliferation and function

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Endogenous itaconate is not required for particulate matter-induced NRF2 expression or inflammatory response

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Time courses of COVID-19 infection and local variation in socioeconomic and health disparities in England

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In-depth analysis reveals complex molecular etiology of idiopathic cerebral palsy

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Exploring the impact of inoculum dose on host immunity and morbidity to inform model-based vaccine design

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Energetic and structural features of SARS-CoV-2 N-protein co-assemblies with nucleic acids

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Bifunctional enzyme SpoT is involved in biofilm formation of Helicobacter pylori with multidrug resistance by upregulating efflux pump Hp1174 (gluP)

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NOGEA: Network-Oriented Gene Entropy Approach for Dissecting Disease Comorbidity and Drug Repositioning

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Two Color Single Molecule Sequencing on GenoCare 1600 Platform to Facilitate Clinical Applications

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Trans-ethnic polygenic analysis supports genetic overlaps of lumbar disc degeneration with height, body mass index, and bone mineral density

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The regulation of mammalian maternal-to-embryonic transition by Eukaryotic translation initiation factor 4E

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Maximizing the Reusability of Gene Expression Data by Predicting Missing Metadata

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Genetic interaction between two unlinked loci underlies the loss of self-incompatibility in Arabidopsis lyrata

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Abnormal nitration and S-sulfhydration of Sp1-CSE-H2S pathway contribute to the progress of HHcy

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WBC-Profiler: an Unsupervised Feature Learning System for Leukocytes Characterization and Classification

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Dietary disparities of urban immigrant schoolchildren in New York City: Results from a mixed-methods pilot study

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Clinical Significance of C4d Deposition in Renal Tissues from Patients with Primary Sj&oumlgren's Syndrome--A Preliminary Study

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A variant in SMOC2, inhibiting BMP signaling by competitively binding to BMPR1B, causes multiple epiphyseal dysplasia

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The collective influence of 1, 25-dihydroxyvitamin D3 with physiological fluid shear stress on osteoblasts

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Impact of Kuntai Capsules on LIF, IGF-1 and EGF Expression in the Implantation Window of Endometrium in Mice

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A study on the protective effects of CpG ODN-induced mucosal immunity against lung injury in a mouse ARDS model

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Insights into the susceptibility of rice to a floral disease

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Fusobacterium nucleatum facilitates cetuximab resistance in colorectal cancer via the PI3K/AKT and JAK/STAT3 pathways

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Proteasome maturation factor UMP1 confers broad-spectrum disease resistance by modulating H2O2 accumulation in rice

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Fucoidan but not 2'-Fucosyllactose could inhibit human norovirus replication in zebrafish larvae

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