Author: John Hardy
- ORCiD: http://orcid.org/0000-0002-3122-0423
- Most recently observed institution: University College London
Rankings
- All-time downloads: 37,689 (rank: 3,881 )
- Categories:
- bioinformatics: 1,953 (rank: 7,406 (tie) )
- genetic and genomic medicine: 1,699 (rank: 1,081 )
- genetics: 10,130 (rank: 1,670 )
- genomics: 2,573 (rank: 9,045 (tie) )
- molecular biology: 294 (rank: 18,602 (tie) )
- neurology: 4,296 (rank: 134 )
- neuroscience: 12,404 (rank: 815 )
- pathology: 4,111 (rank: 279 (tie) )
- systems biology: 229 (rank: 12,171 (tie) )
Downloads per author, site-wide
Preprints
EXCEPTIONALLY LOW LIKELIHOOD OF ALZHEIMER'S DEMENTIA IN APOE2 HOMOZYGOTES
pathology more details view paper- Downloaded 4,111 times
- Download rankings, all-time:
- Site-wide: 2,612
- In pathology: 18
- Year to date:
- Site-wide: 27,205
- Since beginning of last month:
- Site-wide: 26,573
New insights on the genetic etiology of Alzheimer and related dementia
neurology more details view paper- Downloaded 3,399 times
- Download rankings, all-time:
- Site-wide: 3,454
- In neurology: 9
- Year to date:
- Site-wide: 594
- Since beginning of last month:
- Site-wide: 468
Trem2 promotes anti-inflammatory responses in microglia and is suppressed under pro-inflammatory conditions
neuroscience more details view paper- Downloaded 3,249 times
- Download rankings, all-time:
- Site-wide: 3,683
- In neuroscience: 294
- Year to date:
- Site-wide: 13,386
- Since beginning of last month:
- Site-wide: 20,905
G2P: Using machine learning to understand and predict genes causing rare neurological disorders
genetics more details view paper- Downloaded 1,980 times
- Download rankings, all-time:
- Site-wide: 7,557
- In genetics: 355
- Year to date:
- Site-wide: 29,980
- Since beginning of last month:
- Site-wide: 26,253
Genetic variability in response to Aβ deposition influences Alzheimer's risk
neuroscience more details view paper- Downloaded 1,878 times
- Download rankings, all-time:
- Site-wide: 8,186
- In neuroscience: 852
- Year to date:
- Site-wide: 27,007
- Since beginning of last month:
- Site-wide: 31,207
Parkinson disease age of onset GWAS: defining heritability, genetic loci and a-synuclein mechanisms
genetics more details view paper- Downloaded 1,370 times
- Download rankings, all-time:
- Site-wide: 13,081
- In genetics: 644
- Year to date:
- Site-wide: 52,197
- Since beginning of last month:
- Site-wide: 44,268
Genomics implicates adaptive and innate immunity in Alzheimer's and Parkinson's diseases
genomics more details view paper- Downloaded 1,223 times
- Download rankings, all-time:
- Site-wide: 15,580
- In genomics: 1,607
- Year to date:
- Site-wide: 86,702
- Since beginning of last month:
- Site-wide: 95,940
Exome sequencing identifies novel AD-associated genes.
genetic and genomic medicine more details view paper- Downloaded 1,084 times
- Download rankings, all-time:
- Site-wide: 18,606
- In genetic and genomic medicine: 63
- Year to date:
- Site-wide: 10,658
- Since beginning of last month:
- Site-wide: 12,851
Personalized genetic assessment of age associated Alzheimers disease risk
genetics more details view paper- Downloaded 976 times
- Download rankings, all-time:
- Site-wide: 21,613
- In genetics: 1,039
- Year to date:
- Site-wide: 76,402
- Since beginning of last month:
- Site-wide: 54,302
Regulation of mitophagy by the NSL complex underlies genetic risk for Parkinson's disease at Chr16q11.2 and on the MAPT H1 allele.
neuroscience more details view paper- Downloaded 940 times
- Download rankings, all-time:
- Site-wide: 22,897
- In neuroscience: 2,961
- Year to date:
- Site-wide: 20,484
- Since beginning of last month:
- Site-wide: 15,210
An integrated genomic approach to dissect the genetic landscape regulating the cell-to-cell transfer of a-synuclein
neuroscience more details view paper- Downloaded 929 times
- Download rankings, all-time:
- Site-wide: 23,271
- In neuroscience: 3,025
- Year to date:
- Site-wide: 32,892
- Since beginning of last month:
- Site-wide: 42,275
Integration of eQTL and Parkinson's disease GWAS data implicates 11 disease genes
neuroscience more details view paper- Downloaded 923 times
- Download rankings, all-time:
- Site-wide: 23,478
- In neuroscience: 3,069
- Year to date:
- Site-wide: 45,663
- Since beginning of last month:
- Site-wide: 47,089
A genome-wide genetic pleiotropy approach identified shared loci between multiple system atrophy and inflammatory bowel disease
genetics more details view paper- Downloaded 920 times
- Download rankings, all-time:
- Site-wide: 23,625
- In genetics: 1,145
- Year to date:
- Site-wide: 69,747
- Since beginning of last month:
- Site-wide: 55,235
Moving beyond neurons: the role of cell type-specific gene regulation in Parkinson's disease heritability
genomics more details view paper- Downloaded 908 times
- Download rankings, all-time:
- Site-wide: 24,062
- In genomics: 2,309
- Year to date:
- Site-wide: 108,636
- Since beginning of last month:
- Site-wide: 109,240
Genetic modifiers of risk and age at onset in GBA associated Parkinson disease and Lewy body dementia
genetics more details view paper- Downloaded 829 times
- Download rankings, all-time:
- Site-wide: 27,327
- In genetics: 1,328
- Year to date:
- Site-wide: 39,769
- Since beginning of last month:
- Site-wide: 41,356
Atrial Fibrillation Genetic Risk Differentiates Cardioembolic Stroke from other Stroke Subtypes
genetics more details view paper- Downloaded 825 times
- Download rankings, all-time:
- Site-wide: 27,490
- In genetics: 1,333
- Year to date:
- Site-wide: 62,050
- Since beginning of last month:
- Site-wide: 68,392
Common variation at the LRRK2 locus is associated with survival in the primary tauopathy progressive supranuclear palsy
genetics more details view paper- Downloaded 791 times
- Download rankings, all-time:
- Site-wide: 29,177
- In genetics: 1,418
- Year to date:
- Site-wide: 49,130
- Since beginning of last month:
- Site-wide: 53,578
AD-linked R47H-TREM2 mutation induces disease-enhancing proinflammatory microglial states in mice and humans
neuroscience more details view paper- Downloaded 791 times
- Download rankings, all-time:
- Site-wide: 29,176
- In neuroscience: 3,944
- Year to date:
- Site-wide: 21,035
- Since beginning of last month:
- Site-wide: 42,358
Incomplete annotation of disease-associated genes is limiting our understanding of Mendelian and complex neurogenetic disorders
bioinformatics more details view paper- Downloaded 738 times
- Download rankings, all-time:
- Site-wide: 32,207
- In bioinformatics: 3,621
- Year to date:
- Site-wide: 40,743
- Since beginning of last month:
- Site-wide: 33,090
Heritability and genetic variance of dementia with Lewy bodies
neuroscience more details view paper- Downloaded 723 times
- Download rankings, all-time:
- Site-wide: 33,135
- In neuroscience: 4,553
- Year to date:
- Site-wide: 86,703
- Since beginning of last month:
- Site-wide: 88,552
Parkinsons disease determinants, prediction and gene-environment interactions in the UK Biobank
genetics more details view paper- Downloaded 708 times
- Download rankings, all-time:
- Site-wide: 34,061
- In genetics: 1,641
- Year to date:
- Site-wide: 43,255
- Since beginning of last month:
- Site-wide: 53,789
Common and rare variant association analyses in Amyotrophic Lateral Sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology
neurology more details view paper- Downloaded 685 times
- Download rankings, all-time:
- Site-wide: 35,605
- In neurology: 64
- Year to date:
- Site-wide: 1,853
- Since beginning of last month:
- Site-wide: 515
Patient-specific Alzheimer-like pathology in trisomy 21 cerebral organoids reveals BACE2 as a gene-dose-sensitive AD-suppressor in human brain
neuroscience more details view paper- Downloaded 613 times
- Download rankings, all-time:
- Site-wide: 41,093
- In neuroscience: 5,867
- Year to date:
- Site-wide: 47,571
- Since beginning of last month:
- Site-wide: 74,911
Immune-related genetic enrichment in frontotemporal dementia
genetics more details view paper- Downloaded 603 times
- Download rankings, all-time:
- Site-wide: 41,988
- In genetics: 1,994
- Year to date:
- Site-wide: 109,471
- Since beginning of last month:
- Site-wide: 119,857
A locked immunometabolic switch underlies TREM2 R47H loss of function in human iPSC--derived microglia
neuroscience more details view paper- Downloaded 586 times
- Download rankings, all-time:
- Site-wide: 43,487
- In neuroscience: 6,260
- Year to date:
- Site-wide: 95,617
- Since beginning of last month:
- Site-wide: 80,678
The Parkinsons Disease Mendelian Randomization Research Portal
neuroscience more details view paper- Downloaded 508 times
- Download rankings, all-time:
- Site-wide: 51,715
- In neuroscience: 7,633
- Year to date:
- Site-wide: 115,547
- Since beginning of last month:
- Site-wide: 129,769
Sequence of cognitive changes associated with development of Alzheimer's disease in Down syndrome - data driven analysis
neuroscience more details view paper- Downloaded 507 times
- Download rankings, all-time:
- Site-wide: 51,804
- In neuroscience: 7,655
- Year to date:
- Site-wide: 77,105
- Since beginning of last month:
- Site-wide: 102,545
Gene based Analysis in HRC Imputed Genome Wide Association Data Identifies Three Novel Genes for Alzheimer's Disease
genetics more details view paper- Downloaded 506 times
- Download rankings, all-time:
- Site-wide: 51,951
- In genetics: 2,422
- Year to date:
- Site-wide: 120,465
- Since beginning of last month:
- Site-wide: 127,369
Genome-wide association studies of cognitive and motor progression in Parkinson's disease
genetic and genomic medicine more details view paper- Downloaded 505 times
- Download rankings, all-time:
- Site-wide: 52,017
- In genetic and genomic medicine: 166
- Year to date:
- Site-wide: 53,014
- Since beginning of last month:
- Site-wide: 73,025
A comprehensive assessment of benign genetic variability for neurodegenerative disorders
genomics more details view paper- Downloaded 442 times
- Download rankings, all-time:
- Site-wide: 60,304
- In genomics: 4,440
- Year to date:
- Site-wide: 120,545
- Since beginning of last month:
- Site-wide: 109,447
Regulatory sites for known and novel splicing in human basal ganglia are enriched for disease-relevant information
bioinformatics more details view paper- Downloaded 413 times
- Download rankings, all-time:
- Site-wide: 64,555
- In bioinformatics: 6,298
- Year to date:
- Site-wide: 99,817
- Since beginning of last month:
- Site-wide: 117,332
Human-lineage-specific genomic elements: relevance to neurodegenerative disease and APOE transcript usage
neuroscience more details view paper- Downloaded 382 times
- Download rankings, all-time:
- Site-wide: 69,496
- In neuroscience: 10,586
- Year to date:
- Site-wide: 57,727
- Since beginning of last month:
- Site-wide: 57,326
Microglial signalling pathway deficits associated with the R47H TREM2 variant linked to AD indicate inability to activate inflammasome
neuroscience more details view paper- Downloaded 375 times
- Download rankings, all-time:
- Site-wide: 70,768
- In neuroscience: 10,768
- Year to date:
- Site-wide: 16,258
- Since beginning of last month:
- Site-wide: 9,511
Transcriptomic analysis of dystonia-associated genes reveals functional convergence within specific cell types and shared neurobiology with psychiatric disorders
genetics more details view paper- Downloaded 372 times
- Download rankings, all-time:
- Site-wide: 71,285
- In genetics: 3,253
- Year to date:
- Site-wide: 48,733
- Since beginning of last month:
- Site-wide: 53,522
CoExp Web, a web tool for the exploitation of co-expression networks
bioinformatics more details view paper- Downloaded 351 times
- Download rankings, all-time:
- Site-wide: 75,030
- In bioinformatics: 6,992
- Year to date:
- Site-wide: 25,520
- Since beginning of last month:
- Site-wide: 19,692
ERASE: Extended Randomization for assessment of annotation enrichment in ASE datasets
bioinformatics more details view paper- Downloaded 330 times
- Download rankings, all-time:
- Site-wide: 78,878
- In bioinformatics: 7,261
- Year to date:
- Site-wide: 115,471
- Since beginning of last month:
- Site-wide: 78,754
Neurofilament light as a blood biomarker for neurodegeneration in Down syndrome
molecular biology more details view paper- Downloaded 294 times
- Download rankings, all-time:
- Site-wide: 86,165
- In molecular biology: 2,558
- Year to date:
- Site-wide: 126,382
- Since beginning of last month:
- Site-wide: 102,589
Genetic variability associated with OAS1 expression in myeloid cells increases the risk of Alzheimer's disease and severe COVID-19 outcomes
genetics more details view paper- Downloaded 250 times
- Download rankings, all-time:
- Site-wide: 95,701
- In genetics: 4,292
- Year to date:
- Site-wide: 7,801
- Since beginning of last month:
- Site-wide: 2,142
Integrating protein networks and machine learning for disease stratification in the Hereditary Spastic Paraplegias
systems biology more details view paper- Downloaded 229 times
- Download rankings, all-time:
- Site-wide: 100,350
- In systems biology: 2,332
- Year to date:
- Site-wide: 8,856
- Since beginning of last month:
- Site-wide: 55,612
Heritability enrichment implicates microglia in Parkinson's disease pathogenesis
neurology more details view paper- Downloaded 212 times
- Download rankings, all-time:
- Site-wide: 104,371
- In neurology: 328
- Year to date:
- Site-wide: 40,100
- Since beginning of last month:
- Site-wide: 39,313
Modeling multifunctionality of genes with secondary gene co-expression networks in human brain provides novel disease insights
bioinformatics more details view paper- Downloaded 121 times
- Download rankings, all-time:
- Site-wide: 123,244
- In bioinformatics: 9,910
- Year to date:
- Site-wide: 78,043
- Since beginning of last month:
- Site-wide: 100,679
Investigation of Autosomal Genetic Sex Differences in Parkinsons disease
genetic and genomic medicine more details view paper- Downloaded 110 times
- Download rankings, all-time:
- Site-wide: 125,304
- In genetic and genomic medicine: 608
- Year to date:
- Site-wide: 22,650
- Since beginning of last month:
- Site-wide: 14,587
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