Author: Steven Henikoff

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Preprints

Improved CUT&RUN chromatin profiling and analysis tools

• Downloaded 12,124 times
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  • Site-wide: 577
  • In molecular biology: 11
• Year to date:
  • Site-wide: 2,736
• Since beginning of last month:
  • Site-wide: None

Efficient chromatin accessibility mapping in situ by nucleosome-tethered tagmentation

• Downloaded 10,855 times
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  • Site-wide: 672
  • In genomics: 52
• Year to date:
  • Site-wide: 1,605
• Since beginning of last month:
  • Site-wide: 1,774

CUT&RUN: Targeted in situ genome-wide profiling with high efficiency for low cell numbers

• Downloaded 9,371 times
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  • Site-wide: 818
  • In genomics: 67
• Year to date:
  • Site-wide: 5,513
• Since beginning of last month:
  • Site-wide: 3,816

CUT&Tag for efficient epigenomic profiling of small samples and single cells

• Downloaded 8,021 times
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  • Site-wide: 999
  • In genomics: 94
• Year to date:
  • Site-wide: 10,023
• Since beginning of last month:
  • Site-wide: 13,916

Architectural RNA is required for heterochromatin organization

• Downloaded 2,534 times
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  • Site-wide: 4,931
  • In genomics: 573
• Year to date:
  • Site-wide: 12,372
• Since beginning of last month:
  • Site-wide: 10,429

An efficient targeted nuclease strategy for high-resolution mapping of DNA binding sites

• Downloaded 2,137 times
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  • Site-wide: 6,352
  • In genomics: 727
• Year to date:
  • Site-wide: 47,624
• Since beginning of last month:
  • Site-wide: 33,811

Single-cell analysis of chromatin silencing programs in developmental and tumor progression

• Downloaded 1,694 times
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  • Site-wide: 9,014
  • In genomics: 1,010
• Year to date:
  • Site-wide: 3,351
• Since beginning of last month:
  • Site-wide: None

Automated in situ profiling of chromatin modifications resolves cell types and gene regulatory programs

• Downloaded 1,467 times
• Download rankings, all-time:
  • Site-wide: 11,087
  • In genomics: 1,231
• Year to date:
  • Site-wide: 63,964
• Since beginning of last month:
  • Site-wide: 73,799

Histone deposition pathways determine the chromatin landscapes of H3.1 and H3.3 K27M oncohistones

• Downloaded 1,033 times
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  • Site-wide: 18,840
  • In molecular biology: 515
• Year to date:
  • Site-wide: 36,079
• Since beginning of last month:
  • Site-wide: 41,822

Methylation-sensitive expression of a DNA demethylase gene serves as an epigenetic rheostat

• Downloaded 880 times
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  • Site-wide: 23,743
  • In genetics: 1,184
• Year to date:
  • Site-wide: 80,748
• Since beginning of last month:
  • Site-wide: 54,534

Non-B-form DNA structures mark centromeres

• Downloaded 828 times
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  • Site-wide: 25,844
  • In evolutionary biology: 1,234
• Year to date:
  • Site-wide: 88,547
• Since beginning of last month:
  • Site-wide: 91,620

Trans− and cis−acting effects of the lncRNA Firre on epigenetic and structural features of the inactive X chromosome

• Downloaded 701 times
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  • Site-wide: 32,535
  • In genomics: 2,906
• Year to date:
  • Site-wide: 55,004
• Since beginning of last month:
  • Site-wide: 36,791

ChEC-seq kinetics discriminates transcription factor binding sites by DNA sequence and shape in vivo

• Downloaded 690 times
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  • Site-wide: 33,249
  • In genomics: 2,957
• Year to date:
  • Site-wide: 92,174
• Since beginning of last month:
  • Site-wide: 74,918

Automated CUT&Tag profiling of chromatin heterogeneity in mixed-lineage leukemia

• Downloaded 599 times
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  • Site-wide: 40,006
  • In genomics: 3,357
• Year to date:
  • Site-wide: 17,582
• Since beginning of last month:
  • Site-wide: None

Max deletion destabilizes MYC protein and abrogates Eμ-Myc lymphomagenesis

• Downloaded 530 times
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  • Site-wide: 46,498
  • In cancer biology: 1,300
• Year to date:
  • Site-wide: 101,720
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  • Site-wide: None

The H3.3K27M oncohistone antagonizes reprogramming in Drosophila

• Downloaded 253 times
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  • Site-wide: 90,580
  • In genetics: 4,135
• Year to date:
  • Site-wide: 24,077
• Since beginning of last month:
  • Site-wide: 31,196