Author: Hui Zhang

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Preprints

Association of Vitamin D Deficiency and Treatment with COVID-19 Incidence

• Downloaded 13,192 times
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  • Site-wide: 501
  • In infectious diseases: 170
• Year to date:
  • Site-wide: 1,087
• Since beginning of last month:
  • Site-wide: 1,338

The ORF8 Protein of SARS-CoV-2 Mediates Immune Evasion through Potently Downregulating MHC-I

• Downloaded 13,148 times
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  • Site-wide: 507
  • In microbiology: 57
• Year to date:
  • Site-wide: None
• Since beginning of last month:
  • Site-wide: None

A proximity biotinylation map of a human cell

• Downloaded 8,396 times
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  • Site-wide: 939
  • In molecular biology: 14
• Year to date:
  • Site-wide: 2,165
• Since beginning of last month:
  • Site-wide: 1,693

Teicoplanin potently blocks the cell entry of 2019-nCoV

• Downloaded 7,273 times
• Download rankings, all-time:
  • Site-wide: 1,125
  • In microbiology: 102
• Year to date:
  • Site-wide: 6,949
• Since beginning of last month:
  • Site-wide: 9,635

The murine transcriptome reveals global aging nodes with organ-specific phase and amplitude

• Downloaded 3,252 times
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  • Site-wide: 3,450
  • In genomics: 395
• Year to date:
  • Site-wide: 39,669
• Since beginning of last month:
  • Site-wide: None

Image Processing and Quality Control for the first 10,000 Brain Imaging Datasets from UK Biobank

• Downloaded 2,664 times
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  • Site-wide: 4,576
  • In neuroscience: 422
• Year to date:
  • Site-wide: 26,106
• Since beginning of last month:
  • Site-wide: 25,983

Selection of homemade mask materials for preventing transmission of COVID-19: a laboratory study

• Downloaded 2,359 times
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  • Site-wide: 5,484
  • In public and global health: 148
• Year to date:
  • Site-wide: 29,288
• Since beginning of last month:
  • Site-wide: 24,776

L1 and B1 repeats blueprint the spatial organization of chromatin

• Downloaded 2,146 times
• Download rankings, all-time:
  • Site-wide: 6,281
  • In genomics: 721
• Year to date:
  • Site-wide: 11,928
• Since beginning of last month:
  • Site-wide: 11,855

Acoustic Ejection Mass Spectrometry for High-Throughput Analysis

• Downloaded 1,458 times
• Download rankings, all-time:
  • Site-wide: 11,141
  • In biochemistry: 212
• Year to date:
  • Site-wide: 11,738
• Since beginning of last month:
  • Site-wide: 9,798

Mutation rate estimation for 15 autosomal STR loci in a large population from Mainland China

• Downloaded 1,435 times
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  • Site-wide: 11,406
  • In genetics: 567
• Year to date:
  • Site-wide: 92,927
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  • Site-wide: None

A catalog of microbial genes from the bovine rumen unveils a specialized and diverse biomass-degrading environment

• Downloaded 1,213 times
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  • Site-wide: 14,697
  • In microbiology: 826
• Year to date:
  • Site-wide: 39,859
• Since beginning of last month:
  • Site-wide: 35,772

Multi-laboratory assessment of reproducibility, qualitative and quantitative performance of SWATH-mass spectrometry

• Downloaded 1,185 times
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  • Site-wide: 15,220
  • In biochemistry: 295
• Year to date:
  • Site-wide: 90,222
• Since beginning of last month:
  • Site-wide: 65,318

MS-PyCloud: An open-source, cloud computing-based pipeline for LC-MS/MS data analysis

• Downloaded 851 times
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  • Site-wide: 24,766
  • In bioinformatics: 2,944
• Year to date:
  • Site-wide: 17,068
• Since beginning of last month:
  • Site-wide: 11,930

Non-coding germline GATA3 variants alter chromatin topology and contribute to pathogenesis of acute lymphoblastic leukemia

• Downloaded 783 times
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  • Site-wide: 27,803
  • In cancer biology: 724
• Year to date:
  • Site-wide: 26,472
• Since beginning of last month:
  • Site-wide: 16,286

Degradation of SARS-CoV-2 receptor ACE2 by tobacco carcinogen-induced Skp2 in lung epithelial cells

• Downloaded 774 times
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  • Site-wide: 28,224
  • In cell biology: 1,065
• Year to date:
  • Site-wide: 8,210
• Since beginning of last month:
  • Site-wide: 18,174

Diffusion Tensor Model links to Neurite Orientation Dispersion and Density Imaging at high b-value in Cerebral Cortical Gray Matter

• Downloaded 743 times
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  • Site-wide: 29,883
  • In neuroscience: 4,119
• Year to date:
  • Site-wide: 69,487
• Since beginning of last month:
  • Site-wide: 64,888

Deubiquitylation and stabilization of p21 by USP11 is critical for cell cycle progression and DNA damage responses

• Downloaded 718 times
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  • Site-wide: 31,339
  • In cell biology: 1,220
• Year to date:
  • Site-wide: 46,158
• Since beginning of last month:
  • Site-wide: 39,555

Characteristic arrangement of nucleosomes is predictive of chromatin interactions at kilobase resolution

• Downloaded 661 times
• Download rankings, all-time:
  • Site-wide: 35,057
  • In bioinformatics: 3,923
• Year to date:
  • Site-wide: 95,954
• Since beginning of last month:
  • Site-wide: 92,656

OmicsX: a web server for integrated OMICS analysis

• Downloaded 634 times
• Download rankings, all-time:
  • Site-wide: 37,071
  • In bioinformatics: 4,110
• Year to date:
  • Site-wide: 70,037
• Since beginning of last month:
  • Site-wide: 80,767

Characterization and Variation of the Rhizosphere Fungal Community Structure of Cultivated Tetraploid Cotton

• Downloaded 598 times
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  • Site-wide: 39,907
  • In ecology: 965
• Year to date:
  • Site-wide: 43,359
• Since beginning of last month:
  • Site-wide: 33,877

Comprehensive Glycoproteomic Analysis of Chinese Hamster Ovary Cells

• Downloaded 585 times
• Download rankings, all-time:
  • Site-wide: 40,984
  • In biochemistry: 1,032
• Year to date:
  • Site-wide: 71,337
• Since beginning of last month:
  • Site-wide: 58,970

E-cadherin promotes cell hyper-proliferation in breast cancer

• Downloaded 584 times
• Download rankings, all-time:
  • Site-wide: 41,084
  • In cancer biology: 1,132
• Year to date:
  • Site-wide: 34,336
• Since beginning of last month:
  • Site-wide: None

Mapping In Vivo O-Glycoproteome Using Site-specific Extraction of O-linked glycopeptides (EXoO)

• Downloaded 581 times
• Download rankings, all-time:
  • Site-wide: 41,295
  • In systems biology: 966
• Year to date:
  • Site-wide: 83,334
• Since beginning of last month:
  • Site-wide: 93,229

De novo Classification of Mouse B Cell Types using Surfaceome Proteotype Maps

• Downloaded 572 times
• Download rankings, all-time:
  • Site-wide: 42,132
  • In biochemistry: 1,061
• Year to date:
  • Site-wide: 108,258
• Since beginning of last month:
  • Site-wide: 75,440

Genome structure and evolution of Antirrhnum majus L.

• Downloaded 555 times
• Download rankings, all-time:
  • Site-wide: 43,790
  • In genomics: 3,584
• Year to date:
  • Site-wide: 107,012
• Since beginning of last month:
  • Site-wide: 64,942

Reanalysis of global proteomic and phosphoproteomic data identified a large number of glycopeptides

• Downloaded 533 times
• Download rankings, all-time:
  • Site-wide: 45,974
  • In systems biology: 1,075
• Year to date:
  • Site-wide: 58,929
• Since beginning of last month:
  • Site-wide: 42,681

Spatial drivers and pre-cancer populations collaborate with the microenvironment in untreated and chemo-resistant pancreatic cancer

• Downloaded 517 times
• Download rankings, all-time:
  • Site-wide: 47,654
  • In cancer biology: 1,333
• Year to date:
  • Site-wide: 1,181
• Since beginning of last month:
  • Site-wide: 3,257

The Suprachiasmatic Nucleus Regulates Anxiety-Like Behavior in Mice

• Downloaded 487 times
• Download rankings, all-time:
  • Site-wide: 51,107
  • In neuroscience: 7,625
• Year to date:
  • Site-wide: 32,642
• Since beginning of last month:
  • Site-wide: 45,212

Deciphering the roles of N-glycans on collagen-platelet interactions

• Downloaded 481 times
• Download rankings, all-time:
  • Site-wide: 51,870
  • In biochemistry: 1,361
• Year to date:
  • Site-wide: 66,617
• Since beginning of last month:
  • Site-wide: 52,327

Lipid availability influences the metabolic maturation of human pluripotent stem cell-derived cardiomyocytes

• Downloaded 441 times
• Download rankings, all-time:
  • Site-wide: 56,994
  • In cell biology: 2,508
• Year to date:
  • Site-wide: 23,882
• Since beginning of last month:
  • Site-wide: 24,215

Circulating ACE2-expressing Exosomes Block SARS-CoV-2 Virus Infection as an Innate Antiviral Mechanism

• Downloaded 439 times
• Download rankings, all-time:
  • Site-wide: 57,224
  • In immunology: 1,551
• Year to date:
  • Site-wide: 4,798
• Since beginning of last month:
  • Site-wide: None

The depletion of MARVELD1 leads to placenta accreta via integrin β4-dependent trophoblast cell invasion

• Downloaded 423 times
• Download rankings, all-time:
  • Site-wide: 59,427
  • In developmental biology: 1,506
• Year to date:
  • Site-wide: 98,125
• Since beginning of last month:
  • Site-wide: 82,914

OmicsOne: Associate Omics Data with Phenotypes in One-Click

• Downloaded 412 times
• Download rankings, all-time:
  • Site-wide: 61,042
  • In bioinformatics: 6,030
• Year to date:
  • Site-wide: 57,983
• Since beginning of last month:
  • Site-wide: 49,299

CD155/CD96 promotes immunosuppression in lung adenocarcinoma (LUAD)

• Downloaded 380 times
• Download rankings, all-time:
  • Site-wide: 66,057
  • In cancer biology: 1,889
• Year to date:
  • Site-wide: 60,525
• Since beginning of last month:
  • Site-wide: 57,492

Satellite Imaging of Global Urbanicity relate to Adolescent Brain Development and Behavior

• Downloaded 376 times
• Download rankings, all-time:
  • Site-wide: 66,694
  • In neuroscience: 10,214
• Year to date:
  • Site-wide: 48,889
• Since beginning of last month:
  • Site-wide: 35,225

Optimizing the intrinsic parallel diffusivity in NODDI: an extensive empirical evaluation

• Downloaded 351 times
• Download rankings, all-time:
  • Site-wide: 70,868
  • In biophysics: 2,619
• Year to date:
  • Site-wide: 48,114
• Since beginning of last month:
  • Site-wide: 34,832

Comparison of three glycoproteomic methods for the analysis of CHO cells treated with 1,3,4-O-Bu3ManNAc

• Downloaded 312 times
• Download rankings, all-time:
  • Site-wide: 78,077
  • In biochemistry: 2,217
• Year to date:
  • Site-wide: 29,475
• Since beginning of last month:
  • Site-wide: 20,248

Abnormal microstructural development of the cerebral cortex in neonates with congenital heart disease is associated with impaired cerebral oxygen delivery

• Downloaded 309 times
• Download rankings, all-time:
  • Site-wide: 78,587
  • In neuroscience: 12,175
• Year to date:
  • Site-wide: 95,626
• Since beginning of last month:
  • Site-wide: 62,834

EXoO-Tn: Tag-n-Map the Tn Antigen in the Human Proteome

• Downloaded 305 times
• Download rankings, all-time:
  • Site-wide: 79,441
  • In systems biology: 1,920
• Year to date:
  • Site-wide: 85,791
• Since beginning of last month:
  • Site-wide: 83,747

Physiological and transcriptome analysis of indica rice 'MH86' overexpressing OsSPL14

• Downloaded 305 times
• Download rankings, all-time:
  • Site-wide: 79,354
  • In physiology: 656
• Year to date:
  • Site-wide: 114,415
• Since beginning of last month:
  • Site-wide: None

Retinoblastoma 1 (RB1) modulates the proliferation of chicken preadipocytes

• Downloaded 282 times
• Download rankings, all-time:
  • Site-wide: 83,995
  • In genetics: 3,862
• Year to date:
  • Site-wide: 88,918
• Since beginning of last month:
  • Site-wide: None

TERT promoter mutation analysis for blood-based diagnosis and monitoring of gliomas

• Downloaded 280 times
• Download rankings, all-time:
  • Site-wide: 84,473
  • In oncology: 131
• Year to date:
  • Site-wide: 29,126
• Since beginning of last month:
  • Site-wide: 22,050

Mutations in CalDAG-GEFI Lead to Striatal Signaling Deficits and Psychomotor Symptoms in Multiple Species Including Human

• Downloaded 272 times
• Download rankings, all-time:
  • Site-wide: 86,057
  • In neuroscience: 13,395
• Year to date:
  • Site-wide: 48,645
• Since beginning of last month:
  • Site-wide: 84,208

Whole-exome sequencing analysis on products of conception: A cohort study to evaluate clinical utility and genetic etiology for pregnancy loss

• Downloaded 246 times
• Download rankings, all-time:
  • Site-wide: 91,749
  • In genetic and genomic medicine: 323
• Year to date:
  • Site-wide: 56,380
• Since beginning of last month:
  • Site-wide: 69,922

Orthogonal proteomic platforms and their implications for the stable classification of high-grade serous ovarian cancer subtypes

• Downloaded 243 times
• Download rankings, all-time:
  • Site-wide: 92,364
  • In cancer biology: 2,809
• Year to date:
  • Site-wide: 87,801
• Since beginning of last month:
  • Site-wide: 93,293

Proteomic and phosphoproteomic analysis identifies novel liver-related signaling in retinal pigment epithelial cells during epithelial-mesenchymal transition

• Downloaded 224 times
• Download rankings, all-time:
  • Site-wide: 96,484
  • In cell biology: 4,471
• Year to date:
  • Site-wide: 75,434
• Since beginning of last month:
  • Site-wide: 68,421

Ventralis intermedius nucleus anatomical variability assessment by MRI structural connectivity

• Downloaded 194 times
• Download rankings, all-time:
  • Site-wide: 103,068
  • In neuroscience: 16,087
• Year to date:
  • Site-wide: 32,770
• Since beginning of last month:
  • Site-wide: 45,109

Omic-Sig: Utilizing Omics Data to Explore and Visualize Kinase-Substrate Interactions

• Downloaded 189 times
• Download rankings, all-time:
  • Site-wide: 104,112
  • In bioinformatics: 8,833
• Year to date:
  • Site-wide: 114,598
• Since beginning of last month:
  • Site-wide: 80,355

Simultaneously monitoring aquatic and terrestrial biodiversity using riverine water eDNA: seasonal variation of monitoring effectiveness

• Downloaded 177 times
• Download rankings, all-time:
  • Site-wide: 106,528
  • In ecology: 3,710
• Year to date:
  • Site-wide: 52,809
• Since beginning of last month:
  • Site-wide: 44,894

Competitive balance in the big five European leagues based on Shannon entropy

• Downloaded 176 times
• Download rankings, all-time:
  • Site-wide: 106,639
  • In scientific communication and education: 637
• Year to date:
  • Site-wide: 119,665
• Since beginning of last month:
  • Site-wide: 83,459

Expression of endoplasmic reticulum mannosyl-oligosaccharide α1, 2-mannosidase regulates tumorigenicity of prostate cancer cells

• Downloaded 168 times
• Download rankings, all-time:
  • Site-wide: 108,336
  • In cancer biology: 3,340
• Year to date:
  • Site-wide: 110,931
• Since beginning of last month:
  • Site-wide: 76,666

Signal Peptide of HIV-1 Envelope Modulates Glycosylation Impacting Exposure of V1V2 Epitopes

• Downloaded 154 times
• Download rankings, all-time:
  • Site-wide: 110,997
  • In microbiology: 8,377
• Year to date:
  • Site-wide: 73,257
• Since beginning of last month:
  • Site-wide: 37,590

Dopamine Release Neuroenergetics in Mouse Striatal Slices

• Downloaded 143 times
• Download rankings, all-time:
  • Site-wide: 113,235
  • In neuroscience: 17,591
• Year to date:
  • Site-wide: 98,995
• Since beginning of last month:
  • Site-wide: 85,706

Can the response of above- and below-ground traits to overgrazing vary between annual and perennial species?

• Downloaded 122 times
• Download rankings, all-time:
  • Site-wide: 117,094
  • In ecology: 4,234
• Year to date:
  • Site-wide: 122,959
• Since beginning of last month:
  • Site-wide: None

Keratin5-BMP4 mechanosignaling regulates reciprocal acetylation and methylation at H3K9 to define blastema cell remodeling during zebrafish heart regeneration

• Downloaded 96 times
• Download rankings, all-time:
  • Site-wide: 121,558
  • In cell biology: 5,608
• Year to date:
  • Site-wide: 65,378
• Since beginning of last month:
  • Site-wide: 45,357

Interannual variability of net ecosystem carbon production and its climatic and biotic mechanism during 2005-2018 in a rain-fed maize ecosystem

• Downloaded 92 times
• Download rankings, all-time:
  • Site-wide: 122,227
  • In ecology: 4,535
• Year to date:
  • Site-wide: 55,783
• Since beginning of last month:
  • Site-wide: 56,011

Repeatability of soma and neurite metrics in cortical and subcortical grey matter

• Downloaded 88 times
• Download rankings, all-time:
  • Site-wide: 122,860
  • In neuroscience: 19,003
• Year to date:
  • Site-wide: 64,784
• Since beginning of last month:
  • Site-wide: 44,295

Antimicrobial emulsifier – glycerol monolaurate impacts gut micobiome inducing distinct effects on metabolic syndrome in low-fat diet fed mice

• Downloaded 85 times
• Download rankings, all-time:
  • Site-wide: 123,357
  • In microbiology: 9,540
• Year to date:
  • Site-wide: 101,645
• Since beginning of last month:
  • Site-wide: 101,450

Effects of NT5C2 germline variants on 6-mecaptopurine metabolism in children with acute lymphoblastic leukemia

• Downloaded 62 times
• Download rankings, all-time:
  • Site-wide: 126,109
  • In genetics: 5,312
• Year to date:
  • Site-wide: 99,693
• Since beginning of last month:
  • Site-wide: 102,858