Author: Hui Zhang

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Preprints

Robust induction of B cell and T cell responses by a third dose of inactivated SARS-CoV-2 vaccine

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The ORF8 Protein of SARS-CoV-2 Mediates Immune Evasion through Potently Downregulating MHC-I

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  • Site-wide: 506
  • In microbiology: 57
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  • Site-wide: 865
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  • Site-wide: 13,071

Association of Vitamin D Deficiency and Treatment with COVID-19 Incidence

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  • Site-wide: 570
  • In infectious diseases: 201
• Year to date:
  • Site-wide: 1,333
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  • Site-wide: 16,535

A proximity-dependent biotinylation map of a human cell: an interactive web resource

• Downloaded 10,616 times
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  • Site-wide: 880
  • In molecular biology: 16
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  • Site-wide: 893
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  • Site-wide: 40,142

Teicoplanin potently blocks the cell entry of 2019-nCoV

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  • Site-wide: 1,331
  • In microbiology: 126
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  • Site-wide: 7,746
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  • Site-wide: 21,647

The murine transcriptome reveals global aging nodes with organ-specific phase and amplitude

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  • Site-wide: 3,867
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  • Site-wide: 18,356
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  • Site-wide: 86,166

Image Processing and Quality Control for the first 10,000 Brain Imaging Datasets from UK Biobank

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  • Site-wide: 5,198
  • In neuroscience: 452
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  • Site-wide: 18,146

Selection of homemade mask materials for preventing transmission of COVID-19: a laboratory study

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  • Site-wide: 6,441
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  • Site-wide: 41,630
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L1 and B1 repeats blueprint the spatial organization of chromatin

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  • Site-wide: 7,201
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  • Site-wide: 23,176

Acoustic Ejection Mass Spectrometry for High-Throughput Analysis

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  • Site-wide: 9,790
  • In biochemistry: 184
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  • Site-wide: 22,441

Mutation rate estimation for 15 autosomal STR loci in a large population from Mainland China

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  • Site-wide: 13,657
  • In genetics: 628
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  • Site-wide: 103,679
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Multi-laboratory assessment of reproducibility, qualitative and quantitative performance of SWATH-mass spectrometry

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  • Site-wide: 17,670
  • In biochemistry: 356
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  • Site-wide: 83,380
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A catalog of microbial genes from the bovine rumen unveils a specialized and diverse biomass-degrading environment

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  • Site-wide: 17,812
  • In microbiology: 1,040
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  • Site-wide: 99,597
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  • Site-wide: 70,742

Circulating ACE2-expressing Exosomes Block SARS-CoV-2 Virus Infection as an Innate Antiviral Mechanism

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  • Site-wide: 23,219
  • In immunology: 752
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  • Site-wide: 4,384
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  • Site-wide: 34,417

Spatial drivers and pre-cancer populations collaborate with the microenvironment in untreated and chemo-resistant pancreatic cancer

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  • Site-wide: 23,615
  • In cancer biology: 569
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  • Site-wide: 27,672

Non-coding germline GATA3 variants alter chromatin topology and contribute to pathogenesis of acute lymphoblastic leukemia

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  • Site-wide: 25,408
  • In cancer biology: 622
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  • Site-wide: 24,319
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  • Site-wide: 12,971

MS-PyCloud: An open-source, cloud computing-based pipeline for LC-MS/MS data analysis

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  • Site-wide: 25,477
  • In bioinformatics: 2,916
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  • Site-wide: 31,725
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  • Site-wide: 71,339

Degradation of SARS-CoV-2 receptor ACE2 by tobacco carcinogen-induced Skp2 in lung epithelial cells

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  • Site-wide: 29,505
  • In cell biology: 1,098
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  • Site-wide: 104,981

Diffusion Tensor Model links to Neurite Orientation Dispersion and Density Imaging at high b-value in Cerebral Cortical Gray Matter

• Downloaded 796 times
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  • Site-wide: 33,701
  • In neuroscience: 4,515
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  • Site-wide: 84,584
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  • Site-wide: 81,345

Community Evaluation of Glycoproteomics Informatics Solutions Reveals High-Performance Search Strategies of Serum N- and O-Glycopeptide Data

• Downloaded 790 times
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  • Site-wide: 34,091
  • In biochemistry: 813
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  • Site-wide: 1,341

E-cadherin promotes cell hyper-proliferation in breast cancer

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  • Site-wide: 37,148
  • In cancer biology: 997
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  • Site-wide: 31,000
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  • Site-wide: None

Deubiquitylation and stabilization of p21 by USP11 is critical for cell cycle progression and DNA damage responses

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  • Site-wide: 37,696
  • In cell biology: 1,463
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  • Site-wide: 115,229
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Characteristic arrangement of nucleosomes is predictive of chromatin interactions at kilobase resolution

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  • Site-wide: 41,350
  • In bioinformatics: 4,461
• Year to date:
  • Site-wide: 127,370
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OmicsX: a web server for integrated OMICS analysis

• Downloaded 683 times
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  • Site-wide: 41,609
  • In bioinformatics: 4,480
• Year to date:
  • Site-wide: 88,651
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  • Site-wide: 89,295

Characterization and Variation of the Rhizosphere Fungal Community Structure of Cultivated Tetraploid Cotton

• Downloaded 638 times
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  • Site-wide: 45,402
  • In ecology: 1,045
• Year to date:
  • Site-wide: 86,231
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  • Site-wide: 81,762

Comprehensive Glycoproteomic Analysis of Chinese Hamster Ovary Cells

• Downloaded 621 times
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  • Site-wide: 46,991
  • In biochemistry: 1,186
• Year to date:
  • Site-wide: 104,108
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  • Site-wide: 73,369

Mapping In Vivo O-Glycoproteome Using Site-specific Extraction of O-linked glycopeptides (EXoO)

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  • Site-wide: 47,344
  • In systems biology: 1,036
• Year to date:
  • Site-wide: 107,912
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  • Site-wide: None

The Suprachiasmatic Nucleus Regulates Anxiety-Like Behavior in Mice

• Downloaded 611 times
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  • Site-wide: 47,938
  • In neuroscience: 6,839
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  • Site-wide: 38,596
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  • Site-wide: None

Lipid availability influences the metabolic maturation of human pluripotent stem cell-derived cardiomyocytes

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  • Site-wide: 48,814
  • In cell biology: 2,069
• Year to date:
  • Site-wide: 27,923
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  • Site-wide: 96,602

De novo Classification of Mouse B Cell Types using Surfaceome Proteotype Maps

• Downloaded 590 times
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  • Site-wide: 50,092
  • In biochemistry: 1,285
• Year to date:
  • Site-wide: 140,815
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  • Site-wide: None

Genome structure and evolution of Antirrhnum majus L.

• Downloaded 584 times
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  • Site-wide: 50,748
  • In genomics: 3,896
• Year to date:
  • Site-wide: 124,243
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  • Site-wide: 62,101

Reanalysis of global proteomic and phosphoproteomic data identified a large number of glycopeptides

• Downloaded 579 times
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  • Site-wide: 51,351
  • In systems biology: 1,135
• Year to date:
  • Site-wide: 87,484
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  • Site-wide: None

Deciphering the roles of N-glycans on collagen-platelet interactions

• Downloaded 534 times
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  • Site-wide: 56,624
  • In biochemistry: 1,468
• Year to date:
  • Site-wide: 84,343
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  • Site-wide: 73,273

Satellite Imaging of Global Urbanicity relate to Adolescent Brain Development and Behavior

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  • Site-wide: 63,728
  • In neuroscience: 9,392
• Year to date:
  • Site-wide: 49,296
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  • Site-wide: 89,905

OmicsOne: Associate Omics Data with Phenotypes in One-Click

• Downloaded 478 times
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  • Site-wide: 64,215
  • In bioinformatics: 6,281
• Year to date:
  • Site-wide: 71,193
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  • Site-wide: 17,956

The depletion of MARVELD1 leads to placenta accreta via integrin β4-dependent trophoblast cell invasion

• Downloaded 456 times
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  • Site-wide: 67,608
  • In developmental biology: 1,664
• Year to date:
  • Site-wide: 115,682
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  • Site-wide: 68,663

TERT promoter mutation analysis for blood-based diagnosis and monitoring of gliomas

• Downloaded 455 times
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  • Site-wide: 67,773
  • In oncology: 100
• Year to date:
  • Site-wide: 27,132
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  • Site-wide: 56,412

CD155/CD96 promotes immunosuppression in lung adenocarcinoma (LUAD)

• Downloaded 425 times
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  • Site-wide: 72,540
  • In cancer biology: 2,097
• Year to date:
  • Site-wide: 90,286
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  • Site-wide: None

Comparison of three glycoproteomic methods for the analysis of CHO cells treated with 1,3,4-O-Bu3ManNAc

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  • Site-wide: 73,361
  • In biochemistry: 1,996
• Year to date:
  • Site-wide: 42,155
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  • Site-wide: 22,317

Optimizing the intrinsic parallel diffusivity in NODDI: an extensive empirical evaluation

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  • Site-wide: 78,855
  • In biophysics: 2,872
• Year to date:
  • Site-wide: 90,047
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  • Site-wide: None

EXoO-Tn: Tag-n-Map the Tn Antigen in the Human Proteome

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  • Site-wide: 86,890
  • In systems biology: 1,987
• Year to date:
  • Site-wide: 97,930
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  • Site-wide: 62,260

Physiological and transcriptome analysis of indica rice 'MH86' overexpressing OsSPL14

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  • Site-wide: 90,315
  • In physiology: 738
• Year to date:
  • Site-wide: 128,391
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  • Site-wide: 82,402

Retinoblastoma 1 (RB1) modulates the proliferation of chicken preadipocytes

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  • Site-wide: 90,273
  • In genetics: 3,915
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  • Site-wide: 91,903
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Whole-exome sequencing analysis on products of conception: A cohort study to evaluate clinical utility and genetic etiology for pregnancy loss

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  • Site-wide: 90,801
  • In genetic and genomic medicine: 400
• Year to date:
  • Site-wide: 59,977
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  • Site-wide: 100,525

Abnormal microstructural development of the cerebral cortex in neonates with congenital heart disease is associated with impaired cerebral oxygen delivery

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  • Site-wide: 91,654
  • In neuroscience: 13,903
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  • Site-wide: 136,223
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Mutations in CalDAG-GEFI Lead to Striatal Signaling Deficits and Psychomotor Symptoms in Multiple Species Including Human

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  • Site-wide: 95,766
  • In neuroscience: 14,606
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  • Site-wide: 93,445
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  • Site-wide: 87,677

Ventralis intermedius nucleus anatomical variability assessment by MRI structural connectivity

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  • Site-wide: 96,842
  • In neuroscience: 14,764
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  • Site-wide: 43,020
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  • Site-wide: 53,374

Proteomic and phosphoproteomic analysis identifies novel liver-related signaling in retinal pigment epithelial cells during epithelial-mesenchymal transition

• Downloaded 302 times
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  • Site-wide: 97,237
  • In cell biology: 4,450
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  • Site-wide: 95,365

Structures of the human cholecystokinin receptors in complex with agonists and antagonists

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  • Site-wide: 99,334
  • In biophysics: 3,783
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  • Site-wide: 18,279
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  • Site-wide: 27,614

Orthogonal proteomic platforms and their implications for the stable classification of high-grade serous ovarian cancer subtypes

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  • Site-wide: 103,937
  • In cancer biology: 3,126
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  • Site-wide: 117,120
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  • Site-wide: 61,033

On the generalizability of diffusion MRI signal representations across acquisition parameters, sequences and tissue types: chronicles of the MEMENTO challenge.

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  • Site-wide: 104,962
  • In neuroscience: 16,064
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  • Site-wide: 49,250

Simultaneously monitoring aquatic and terrestrial biodiversity using riverine water eDNA: seasonal variation of monitoring effectiveness

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  • Site-wide: 114,963
  • In ecology: 3,728
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  • Site-wide: 81,226
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  • Site-wide: 50,902

The efficacy and safety of remdesivir in the treatment of patients with COVID-19: a systematic review and meta-analysis

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  • Site-wide: 116,549
  • In epidemiology: 4,875
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  • Site-wide: 26,601
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  • Site-wide: 49,775

Training Data Distribution Significantly Impacts the Estimation of Tissue Microstructure with Machine Learning

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  • Site-wide: 117,560
  • In neuroscience: 17,977
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  • Site-wide: 27,145
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  • Site-wide: 16,805

Omic-Sig: Utilizing Omics Data to Explore and Visualize Kinase-Substrate Interactions

• Downloaded 211 times
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  • Site-wide: 119,398
  • In bioinformatics: 9,775
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  • Site-wide: 138,261
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  • Site-wide: None

Expression of endoplasmic reticulum mannosyl-oligosaccharide α1, 2-mannosidase regulates tumorigenicity of prostate cancer cells

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  • Site-wide: 120,904
  • In cancer biology: 3,659
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  • Site-wide: 116,698
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  • Site-wide: 89,378

Clinical characteristics of COVID-19 in children and adolescents: a systematic review and meta-analysis

• Downloaded 200 times
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  • Site-wide: 122,032
  • In epidemiology: 5,111
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  • Site-wide: 30,102
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  • Site-wide: 116,437

Signal Peptide of HIV-1 Envelope Modulates Glycosylation Impacting Exposure of V1V2 Epitopes

• Downloaded 196 times
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  • Site-wide: 122,995
  • In microbiology: 9,208
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  • Site-wide: 97,510
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A novel method for generating 3D constructs with branched vascular networks using multi-materials bioprinting and direct surgical anastomosis

• Downloaded 189 times
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  • Site-wide: 124,664
  • In bioengineering: 2,472
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  • Site-wide: 32,484
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  • Site-wide: 50,143

Competitive balance in the big five European leagues based on Shannon entropy

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  • Site-wide: 125,526
  • In scientific communication and education: 727
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  • Site-wide: 151,611
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  • Site-wide: None

Dopamine Release Neuroenergetics in Mouse Striatal Slices

• Downloaded 179 times
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  • Site-wide: 126,969
  • In neuroscience: 19,366
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  • Site-wide: 112,388
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  • Site-wide: 113,760

Antimicrobial emulsifier – glycerol monolaurate impacts gut micobiome inducing distinct effects on metabolic syndrome in low-fat diet fed mice

• Downloaded 150 times
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  • Site-wide: 133,544
  • In microbiology: 10,161
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  • Site-wide: 81,409
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  • Site-wide: 20,310

Interannual variability of net ecosystem carbon production and its climatic and biotic mechanism during 2005-2018 in a rain-fed maize ecosystem

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  • Site-wide: 135,609
  • In ecology: 4,746
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  • Site-wide: 83,824
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  • Site-wide: None

Can the response of above- and below-ground traits to overgrazing vary between annual and perennial species?

• Downloaded 136 times
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  • Site-wide: 136,698
  • In ecology: 4,795
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  • Site-wide: 150,856
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Repeatability of soma and neurite metrics in cortical and subcortical grey matter

• Downloaded 130 times
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  • Site-wide: 137,895
  • In neuroscience: 20,935
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  • Site-wide: 94,934
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  • Site-wide: None

Keratin5-BMP4 mechanosignaling regulates reciprocal acetylation and methylation at H3K9 to define blastema cell remodeling during zebrafish heart regeneration

• Downloaded 123 times
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  • Site-wide: 139,372
  • In cell biology: 6,341
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  • Site-wide: 112,700
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  • Site-wide: 99,878

Effects of NT5C2 germline variants on 6-mecaptopurine metabolism in children with acute lymphoblastic leukemia

• Downloaded 92 times
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  • Site-wide: 145,242
  • In genetics: 5,740
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  • Site-wide: 120,576
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  • Site-wide: None

Loss and Reorganisation of Superficial White Matter in Alzheimer's disease: A Diffusion MRI study

• Downloaded 91 times
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  • Site-wide: 145,322
  • In neurology: 775
• Year to date:
  • Site-wide: 68,806
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  • Site-wide: 27,455

Not all voxels are created equal: reducing estimation bias in regional NODDI metrics using tissue-weighted means

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  • Site-wide: 151,342
  • In neuroscience: 22,819
• Year to date:
  • Site-wide: 135,476
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  • Site-wide: 112,163

Constructing a warhead of PROTAC with aptamer for tumor-selective degradation of nucleolin

• Downloaded 23 times
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  • Site-wide: 151,591
  • In biochemistry: 4,569
• Year to date:
  • Site-wide: 143,830
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  • Site-wide: 2,706

Optimized Data-Independent Acquisition Approach for Proteomic Analysis at Single-Cell Level

• Downloaded 14 times
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  • Site-wide: 152,105
  • In systems biology: 3,124
• Year to date:
  • Site-wide: 151,284
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  • Site-wide: 5,393

An ultrapotent neutralizing bispecific antibody with broad spectrum against SARS-CoV-2 variants

• Downloaded 7 times
• Download rankings, all-time:
  • Site-wide: 153,011
  • In microbiology: 11,978
• Year to date:
  • Site-wide: 152,907
• Since beginning of last month:
  • Site-wide: 10,991