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Author: Hao Wu

  • ORCiD: http://orcid.org/0000-0003-4395-6929
  • Most recently observed institution: Key Laboratory of Biomedical Information Engineering of Ministry of Education, Biomedical Informatics & Genomics Center, School of Life Science and Technology, Xi'an Jiaotong University

Rankings

  • All-time downloads: 50,576 (rank: 3,183 )
  • Categories:
    • biochemistry: 354 (rank: 16,364 (tie) )
    • bioinformatics: 781 (rank: 19,405 (tie) )
    • biophysics: 510 (rank: 11,303 (tie) )
    • cancer biology: 2,348 (rank: 2,590 (tie) )
    • cell biology: 2,994 (rank: 1,819 )
    • developmental biology: 266 (rank: 16,540 (tie) )
    • epidemiology: 1,738 (rank: 6,956 (tie) )
    • genetics: 669 (rank: 22,168 (tie) )
    • genomics: 10,135 (rank: 2,027 )
    • immunology: 10,715 (rank: 803 )
    • infectious diseases: 2,247 (rank: 15,186 (tie) )
    • microbiology: 167 (rank: 56,699 (tie) )
    • molecular biology: 3,286 (rank: 1,313 (tie) )
    • neuroscience: 12,225 (rank: 1,028 )
    • oncology: 198 (rank: 4,002 (tie) )
    • otolaryngology: 349 (rank: 416 (tie) )
    • physiology: 497 (rank: 3,369 (tie) )
    • plant biology: 518 (rank: 9,621 (tie) )
    • psychiatry and clinical psychology: 306 (rank: 3,718 (tie) )
    • synthetic biology: 273 (rank: 5,042 (tie) )

Downloads per author, site-wide

Preprints

Identification of pyroptosis inhibitors that target a reactive cysteine in gasdermin D

immunology more details view paper
  • Downloaded 5,001 times
  • Download rankings, all-time:
    • Site-wide: 2,288
    • In immunology: 74
  • Year to date:
    • Site-wide: 6,842
  • Since beginning of last month:
    • Site-wide: 6,899

All-optical electrophysiology reveals brain-state dependent changes in hippocampal subthreshold dynamics and excitability

neuroscience more details view paper
  • Downloaded 4,581 times
  • Download rankings, all-time:
    • Site-wide: 2,582
    • In neuroscience: 160
  • Year to date:
    • Site-wide: 45,115
  • Since beginning of last month:
    • Site-wide: 40,133

sNucDrop-Seq: Dissecting cell-type composition and neuronal activity state in mammalian brains by massively parallel single-nucleus RNA-Seq

genomics more details view paper
  • Downloaded 2,582 times
  • Download rankings, all-time:
    • Site-wide: 5,844
    • In genomics: 622
  • Year to date:
    • Site-wide: 65,436
  • Since beginning of last month:
    • Site-wide: 94,172

Massively parallel, time-resolved single-cell RNA sequencing with scNT-Seq

genomics more details view paper
  • Downloaded 2,439 times
  • Download rankings, all-time:
    • Site-wide: 6,393
    • In genomics: 688
  • Year to date:
    • Site-wide: 20,802
  • Since beginning of last month:
    • Site-wide: 39,558

All-optical electrophysiology reveals excitation, inhibition, and neuromodulation in cortical layer 1

neuroscience more details view paper
  • Downloaded 2,314 times
  • Download rankings, all-time:
    • Site-wide: 6,884
    • In neuroscience: 649
  • Year to date:
    • Site-wide: 88,291
  • Since beginning of last month:
    • Site-wide: 133,979

SARS-CoV-2 infects blood monocytes to activate NLRP3 and AIM2 inflammasomes, pyroptosis and cytokine release

infectious diseases more details view paper
  • Downloaded 2,247 times
  • Download rankings, all-time:
    • Site-wide: 7,202
    • In infectious diseases: 1,093
  • Year to date:
    • Site-wide: 953
  • Since beginning of last month:
    • Site-wide: 1,059

Cryo-EM structure of an activated GPCR-G protein complex in lipid nanodiscs

molecular biology more details view paper
  • Downloaded 1,902 times
  • Download rankings, all-time:
    • Site-wide: 9,200
    • In molecular biology: 238
  • Year to date:
    • Site-wide: 10,900
  • Since beginning of last month:
    • Site-wide: 31,313

A genetically encoded fluorescent sensor for rapid and specific in vivo detection of norepinephrine

neuroscience more details view paper
  • Downloaded 1,791 times
  • Download rankings, all-time:
    • Site-wide: 10,055
    • In neuroscience: 1,046
  • Year to date:
    • Site-wide: 78,081
  • Since beginning of last month:
    • Site-wide: 96,707

SARS-CoV-2 Nsp1 suppresses host but not viral translation through a bipartite mechanism

cell biology more details view paper
  • Downloaded 1,674 times
  • Download rankings, all-time:
    • Site-wide: 11,097
    • In cell biology: 282
  • Year to date:
    • Site-wide: 5,028
  • Since beginning of last month:
    • Site-wide: 8,781

Single cell transcriptomic analysis of the adult mouse pituitary reveals a novel multi-hormone cell cluster and physiologic demand-induced lineage plasticity

genomics more details view paper
  • Downloaded 1,586 times
  • Download rankings, all-time:
    • Site-wide: 12,008
    • In genomics: 1,249
  • Year to date:
    • Site-wide: 27,035
  • Since beginning of last month:
    • Site-wide: 45,163

Loss of SDHB reprograms energy metabolisms and inhibits high fat diet induced metabolic syndromes

molecular biology more details view paper
  • Downloaded 1,384 times
  • Download rankings, all-time:
    • Site-wide: 14,698
    • In molecular biology: 401
  • Year to date:
    • Site-wide: 15,009
  • Since beginning of last month:
    • Site-wide: 13,845

A GRAB sensor reveals activity-dependent non-vesicular somatodendritic adenosine release

neuroscience more details view paper
  • Downloaded 1,319 times
  • Download rankings, all-time:
    • Site-wide: 15,807
    • In neuroscience: 1,856
  • Year to date:
    • Site-wide: 12,375
  • Since beginning of last month:
    • Site-wide: 22,980

BTK operates a phospho-tyrosine switch to regulate NLRP3 inflammasome activity

immunology more details view paper
  • Downloaded 1,223 times
  • Download rankings, all-time:
    • Site-wide: 17,696
    • In immunology: 565
  • Year to date:
    • Site-wide: 20,389
  • Since beginning of last month:
    • Site-wide: 25,582

Effect of large-scale testing platform in prevention and control of the COVID-19 pandemic: an empirical study with a novel numerical model

epidemiology more details view paper
  • Downloaded 1,205 times
  • Download rankings, all-time:
    • Site-wide: 18,108
    • In epidemiology: 1,148
  • Year to date:
    • Site-wide: 55,693
  • Since beginning of last month:
    • Site-wide: 46,822

DPP9 directly sequesters the NLRP1 C-terminus to repress inflammasome activation

immunology more details view paper
  • Downloaded 1,044 times
  • Download rankings, all-time:
    • Site-wide: 22,412
    • In immunology: 711
  • Year to date:
    • Site-wide: 17,438
  • Since beginning of last month:
    • Site-wide: 24,339

Predictive modeling of single-cell DNA methylome data enhances integration with transcriptome data

genomics more details view paper
  • Downloaded 1,005 times
  • Download rankings, all-time:
    • Site-wide: 23,610
    • In genomics: 2,246
  • Year to date:
    • Site-wide: 10,439
  • Since beginning of last month:
    • Site-wide: 24,613

The impact of tumor stromal architecture on therapy response and clinical progression

cancer biology more details view paper
  • Downloaded 959 times
  • Download rankings, all-time:
    • Site-wide: 25,341
    • In cancer biology: 622
  • Year to date:
    • Site-wide: 72,223
  • Since beginning of last month:
    • Site-wide: 69,195

Spatially coordinated heterochromatinization of distal short tandem repeats in fragile X syndrome

genomics more details view paper
  • Downloaded 842 times
  • Download rankings, all-time:
    • Site-wide: 30,399
    • In genomics: 2,707
  • Year to date:
    • Site-wide: 3,520
  • Since beginning of last month:
    • Site-wide: 3,681

Elevated SARS-CoV-2 Antibodies Distinguish Severe Disease in Early COVID-19 Infection

immunology more details view paper
  • Downloaded 798 times
  • Download rankings, all-time:
    • Site-wide: 32,780
    • In immunology: 1,018
  • Year to date:
    • Site-wide: 11,098
  • Since beginning of last month:
    • Site-wide: 11,745

Electron Microscopic Reconstruction of Neural Circuitry in the Cochlea

neuroscience more details view paper
  • Downloaded 749 times
  • Download rankings, all-time:
    • Site-wide: 35,773
    • In neuroscience: 4,849
  • Year to date:
    • Site-wide: 63,318
  • Since beginning of last month:
    • Site-wide: 103,751

Single-cell multi-omics reveals elevated plasticity and stem-cell-like blasts relevant to the poor prognosis of KMT2A-rearranged leukemia

cancer biology more details view paper
  • Downloaded 704 times
  • Download rankings, all-time:
    • Site-wide: 39,012
    • In cancer biology: 1,059
  • Year to date:
    • Site-wide: 9,686
  • Since beginning of last month:
    • Site-wide: 15,938

Stress-induced epigenetic regulation of transcription in neocortical excitatory neurons drives depression-like behavior

neuroscience more details view paper
  • Downloaded 701 times
  • Download rankings, all-time:
    • Site-wide: 39,183
    • In neuroscience: 5,404
  • Year to date:
    • Site-wide: 21,147
  • Since beginning of last month:
    • Site-wide: 28,401

Dynamic changes in the regulatory T cell heterogeneity and function by murine IL-2 mutein

immunology more details view paper
  • Downloaded 694 times
  • Download rankings, all-time:
    • Site-wide: 39,734
    • In immunology: 1,222
  • Year to date:
    • Site-wide: 102,411
  • Since beginning of last month:
    • Site-wide: 95,453

Small molecule inhibitors of G9a reactivate the maternal PWS genes in Prader-Willi-Syndrome patient derived neural stem cells and differentiated neurons

cell biology more details view paper
  • Downloaded 690 times
  • Download rankings, all-time:
    • Site-wide: 39,994
    • In cell biology: 1,618
  • Year to date:
    • Site-wide: 32,940
  • Since beginning of last month:
    • Site-wide: 75,514

Novel mode of filament formation in UPA-promoted CARD8 and NLRP1 Inflammasomes

immunology more details view paper
  • Downloaded 658 times
  • Download rankings, all-time:
    • Site-wide: 42,538
    • In immunology: 1,287
  • Year to date:
    • Site-wide: 67,977
  • Since beginning of last month:
    • Site-wide: 67,205

Partial FMRP expression is sufficient to normalize neuronal hyperactivity in Fragile X neurons

neuroscience more details view paper
  • Downloaded 656 times
  • Download rankings, all-time:
    • Site-wide: 42,725
    • In neuroscience: 5,980
  • Year to date:
    • Site-wide: 85,347
  • Since beginning of last month:
    • Site-wide: 98,567

Molecular mapping of transmembrane mechanotransduction through the β1 integrin-CD98hc-TRPV4 axis

cell biology more details view paper
  • Downloaded 630 times
  • Download rankings, all-time:
    • Site-wide: 44,956
    • In cell biology: 1,869
  • Year to date:
    • Site-wide: 60,067
  • Since beginning of last month:
    • Site-wide: 55,485

Identifying Lineage-specific Targets of Darwinian Selection by a Bayesian Analysis of Genomic Polymorphisms and Divergence from Multiple Species

genomics more details view paper
  • Downloaded 601 times
  • Download rankings, all-time:
    • Site-wide: 47,700
    • In genomics: 3,738
  • Year to date:
    • Site-wide: 79,394
  • Since beginning of last month:
    • Site-wide: 96,368

Lactate dehydrogenases amplify reactive oxygen species in cancer cells in response to oxidative stimuli

cancer biology more details view paper
  • Downloaded 598 times
  • Download rankings, all-time:
    • Site-wide: 48,005
    • In cancer biology: 1,349
  • Year to date:
    • Site-wide: 41,938
  • Since beginning of last month:
    • Site-wide: 40,234

Quantitative single cell 5hmC sequencing reveals non-canonical gene regulation by non-CG hydroxymethylation

genomics more details view paper
  • Downloaded 558 times
  • Download rankings, all-time:
    • Site-wide: 52,366
    • In genomics: 4,003
  • Year to date:
    • Site-wide: 6,414
  • Since beginning of last month:
    • Site-wide: 13,546

Structural mechanism of CARD8 regulation by DPP9

immunology more details view paper
  • Downloaded 547 times
  • Download rankings, all-time:
    • Site-wide: 53,564
    • In immunology: 1,597
  • Year to date:
    • Site-wide: 6,609
  • Since beginning of last month:
    • Site-wide: 39,086

Disulfiram associated with lower risk of Covid-19: a retrospective cohort study

epidemiology more details view paper
  • Downloaded 533 times
  • Download rankings, all-time:
    • Site-wide: 55,356
    • In epidemiology: 2,501
  • Year to date:
    • Site-wide: 6,902
  • Since beginning of last month:
    • Site-wide: 16,869

Molecular signatures associated with ZIKV exposure in human cortical neural progenitors

genomics more details view paper
  • Downloaded 522 times
  • Download rankings, all-time:
    • Site-wide: 56,612
    • In genomics: 4,241
  • Year to date:
    • Site-wide: 140,815
  • Since beginning of last month:
    • Site-wide: 118,209

Redundant SCARECROW genes pattern distinct cell layers in roots and leaves of maize

plant biology more details view paper
  • Downloaded 518 times
  • Download rankings, all-time:
    • Site-wide: 57,251
    • In plant biology: 1,392
  • Year to date:
    • Site-wide: 102,136
  • Since beginning of last month:
    • Site-wide: 114,814

Lymph Nodes Inhibit T-cell Effector Functions Locally by Establishing Acidic Niches

physiology more details view paper
  • Downloaded 497 times
  • Download rankings, all-time:
    • Site-wide: 60,002
    • In physiology: 374
  • Year to date:
    • Site-wide: 115,971
  • Since beginning of last month:
    • Site-wide: 89,110

Dissecting differential signals in high-throughput data from complex tissues

bioinformatics more details view paper
  • Downloaded 442 times
  • Download rankings, all-time:
    • Site-wide: 68,079
    • In bioinformatics: 6,520
  • Year to date:
    • Site-wide: 95,290
  • Since beginning of last month:
    • Site-wide: 113,963

Longitudinally persistent cerebrospinal fluid B-cells resist treatment in multiple sclerosis

immunology more details view paper
  • Downloaded 404 times
  • Download rankings, all-time:
    • Site-wide: 74,341
    • In immunology: 2,187
  • Year to date:
    • Site-wide: 88,397
  • Since beginning of last month:
    • Site-wide: 51,101

CG14906 (mettl4) mediates m6A methylation of U2 snRNA in Drosophila

biochemistry more details view paper
  • Downloaded 354 times
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    • Site-wide: 83,744
    • In biochemistry: 2,348
  • Year to date:
    • Site-wide: 116,694
  • Since beginning of last month:
    • Site-wide: 100,590

The Characteristic of Auditory Function and Cochlear Pathophysiology in a Noise-exposed Cohort: A Cross-sectional Study

otolaryngology more details view paper
  • Downloaded 349 times
  • Download rankings, all-time:
    • Site-wide: 84,591
    • In otolaryngology: 57
  • Year to date:
    • Site-wide: 31,473
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    • Site-wide: 35,222

Dissecting molecular regulatory mechanisms underlying noncoding susceptibility SNPs associated with 19 autoimmune diseases using multi-omics integrative analysis

immunology more details view paper
  • Downloaded 346 times
  • Download rankings, all-time:
    • Site-wide: 85,279
    • In immunology: 2,498
  • Year to date:
    • Site-wide: 95,949
  • Since beginning of last month:
    • Site-wide: 67,255

Double triage to identify poorly annotated genes in Maize: The missing link in community curation

bioinformatics more details view paper
  • Downloaded 339 times
  • Download rankings, all-time:
    • Site-wide: 86,688
    • In bioinformatics: 7,791
  • Year to date:
    • Site-wide: 136,707
  • Since beginning of last month:
    • Site-wide: 115,284

Getting in shape and swimming: the role of cortical forces and membrane heterogeneity in eukaryotic cells

biophysics more details view paper
  • Downloaded 339 times
  • Download rankings, all-time:
    • Site-wide: 86,664
    • In biophysics: 3,256
  • Year to date:
    • Site-wide: 141,057
  • Since beginning of last month:
    • Site-wide: 131,965

Epigenetic Element-Based Transcriptome-Wide Association Study Identifies Novel Genes for Bipolar Disorder

psychiatry and clinical psychology more details view paper
  • Downloaded 306 times
  • Download rankings, all-time:
    • Site-wide: 94,070
    • In psychiatry and clinical psychology: 360
  • Year to date:
    • Site-wide: 51,395
  • Since beginning of last month:
    • Site-wide: 33,834

Genetic analysis of the STIM1 gene in chronic pancreatitis

genetics more details view paper
  • Downloaded 284 times
  • Download rankings, all-time:
    • Site-wide: 98,949
    • In genetics: 4,275
  • Year to date:
    • Site-wide: 102,580
  • Since beginning of last month:
    • Site-wide: 108,205

THOC1 deficiency leads to late-onset nonsyndromic hearing loss through p53-mediated hair cell apoptosis

genetics more details view paper
  • Downloaded 275 times
  • Download rankings, all-time:
    • Site-wide: 101,047
    • In genetics: 4,355
  • Year to date:
    • Site-wide: 140,519
  • Since beginning of last month:
    • Site-wide: 135,617

Programmable pattern formation in cellular systems with local signaling

synthetic biology more details view paper
  • Downloaded 273 times
  • Download rankings, all-time:
    • Site-wide: 101,490
    • In synthetic biology: 1,005
  • Year to date:
    • Site-wide: 17,873
  • Since beginning of last month:
    • Site-wide: 46,094

Human retinal organoids release extracellular vesicles that regulate gene expression in target human retinal progenitors

developmental biology more details view paper
  • Downloaded 266 times
  • Download rankings, all-time:
    • Site-wide: 103,217
    • In developmental biology: 2,779
  • Year to date:
    • Site-wide: 18,440
  • Since beginning of last month:
    • Site-wide: 18,617

Highly Robust Prediction of Lung Nodule Malignancy by Deep Learning Model: A Multiracial, Multinational Study

oncology more details view paper
  • Downloaded 198 times
  • Download rankings, all-time:
    • Site-wide: 119,655
    • In oncology: 297
  • Year to date:
    • Site-wide: 57,415
  • Since beginning of last month:
    • Site-wide: 36,853

Binding Dynamics of Disordered Linker Histone H1 with a Nucleosomal Particle

biophysics more details view paper
  • Downloaded 171 times
  • Download rankings, all-time:
    • Site-wide: 126,206
    • In biophysics: 4,847
  • Year to date:
    • Site-wide: 75,731
  • Since beginning of last month:
    • Site-wide: 86,129

Novel Immunoassay for Diagnosis of Ongoing Clostridioides difficile Infections Using Serum and Medium Enriched for Newly Synthesized Antibodies (MENSA)

microbiology more details view paper
  • Downloaded 167 times
  • Download rankings, all-time:
    • Site-wide: 126,994
    • In microbiology: 9,554
  • Year to date:
    • Site-wide: 82,879
  • Since beginning of last month:
    • Site-wide: 53,570

Brain image-derived phenotypes yield insights into causal risk of psychiatric disorders using a Mendelian randomization study

neuroscience more details view paper
  • Downloaded 114 times
  • Download rankings, all-time:
    • Site-wide: 138,469
    • In neuroscience: 20,906
  • Year to date:
    • Site-wide: 50,095
  • Since beginning of last month:
    • Site-wide: 23,533

Phenome-wide investigation of the causal associations between childhood BMI and adult outcomes: A two-sample Mendelian randomization study

genetics more details view paper
  • Downloaded 110 times
  • Download rankings, all-time:
    • Site-wide: 139,158
    • In genetics: 5,597
  • Year to date:
    • Site-wide: 110,057
  • Since beginning of last month:
    • Site-wide: 72,793

Integrative Analysis the characterization of peroxiredoxins in pan-cancer

cancer biology more details view paper
  • Downloaded 87 times
  • Download rankings, all-time:
    • Site-wide: 143,254
    • In cancer biology: 4,446
  • Year to date:
    • Site-wide: 110,037
  • Since beginning of last month:
    • Site-wide: 124,293

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