Author: Yan Wang

Downloads per author, site-wide

Preprints

Kaposi's Sarcoma-associated Herpesvirus Promotes Mesenchymal-to-Endothelial Transition by Resolving the Bivalent Chromatin of PROX1 Gene

No download data for this paper yet.

Kaposi's Sarcoma-associated Herpesvirus vFLIP Promotes MEndT to Generate Hybrid M/E State for Tumorigenesis

No download data for this paper yet.

Geraniol Enhances Inhibitory Inputs to Paraventricular Thalamic Nucleus and Induces Sedation in Mice

No download data for this paper yet.

Activin B Promotes the Initiation and Progression of Liver Fibrosis

No download data for this paper yet.

Role of PARP1 in oligodendrocyte differentiation during developmental myelination and remyelination after myelin damage

No download data for this paper yet.

Integrative molecular and clinical profiling of acral melanoma identifies LZTR1 as a key tumor promoter and therapeutic target

No download data for this paper yet.

Age profile of susceptibility, mixing, and social distancing shape the dynamics of the novel coronavirus disease 2019 outbreak in China

• Downloaded 10,465 times
• Download rankings, all-time:
  • Site-wide: 773
  • In epidemiology: 111
• Year to date:
  • Site-wide: 10,384
• Since beginning of last month:
  • Site-wide: 10,417

Prevalence and Risk Factors for Acute Posttraumatic Stress Disorder during the COVID-19 Outbreak

• Downloaded 6,405 times
• Download rankings, all-time:
  • Site-wide: 1,454
  • In psychiatry and clinical psychology: 6
• Year to date:
  • Site-wide: 2,925
• Since beginning of last month:
  • Site-wide: 3,123

Detection of 2019 novel coronavirus in semen and testicular biopsy specimen of COVID-19 patients

• Downloaded 4,350 times
• Download rankings, all-time:
  • Site-wide: 2,497
  • In infectious diseases: 537
• Year to date:
  • Site-wide: 12,274
• Since beginning of last month:
  • Site-wide: 16,165

Evolving epidemiology of novel coronavirus diseases 2019 and possible interruption of local transmission outside Hubei Province in China: a descriptive and modeling study

• Downloaded 3,765 times
• Download rankings, all-time:
  • Site-wide: 3,076
  • In infectious diseases: 611
• Year to date:
  • Site-wide: 19,182
• Since beginning of last month:
  • Site-wide: 16,777

Infectivity, susceptibility, and risk factors associated with SARS-CoV-2 transmission under intensive contact tracing in Hunan, China

• Downloaded 2,721 times
• Download rankings, all-time:
  • Site-wide: 4,883
  • In infectious diseases: 820
• Year to date:
  • Site-wide: 4,893
• Since beginning of last month:
  • Site-wide: 13,046

MECAT: an ultra-fast mapping, error correction and de novo assembly tool for single-molecule sequencing reads

• Downloaded 2,587 times
• Download rankings, all-time:
  • Site-wide: 5,236
  • In bioinformatics: 566
• Year to date:
  • Site-wide: 99,845
• Since beginning of last month:
  • Site-wide: 87,521

Case fatality risk of novel coronavirus diseases 2019 in China

• Downloaded 2,000 times
• Download rankings, all-time:
  • Site-wide: 7,669
  • In infectious diseases: 1,061
• Year to date:
  • Site-wide: 41,214
• Since beginning of last month:
  • Site-wide: 40,819

Dual midbrain and forebrain origins of thalamic inhibitory interneurons

• Downloaded 1,955 times
• Download rankings, all-time:
  • Site-wide: 7,937
  • In neuroscience: 808
• Year to date:
  • Site-wide: 19,720
• Since beginning of last month:
  • Site-wide: 36,019

High risk of infection caused posttraumatic stress symptoms in individuals with poor sleep quality: A study on influence of coronavirus disease (COVID-19) in China

• Downloaded 1,848 times
• Download rankings, all-time:
  • Site-wide: 8,634
  • In psychiatry and clinical psychology: 30
• Year to date:
  • Site-wide: 21,716
• Since beginning of last month:
  • Site-wide: 12,204

A statistical framework for mapping risk genes from de novo mutations in whole-genome sequencing studies

• Downloaded 1,815 times
• Download rankings, all-time:
  • Site-wide: 8,885
  • In genetics: 410
• Year to date:
  • Site-wide: 71,086
• Since beginning of last month:
  • Site-wide: 69,248

Transmission heterogeneities, kinetics, and controllability of SARS-CoV-2

• Downloaded 1,701 times
• Download rankings, all-time:
  • Site-wide: 9,795
  • In epidemiology: 717
• Year to date:
  • Site-wide: 20,413
• Since beginning of last month:
  • Site-wide: 29,865

Simulating and Forecasting the Cumulative Confirmed Cases of SARS-CoV-2 in China by Boltzmann Function-based Regression Analyses

• Downloaded 1,688 times
• Download rankings, all-time:
  • Site-wide: 9,900
  • In infectious diseases: 1,228
• Year to date:
  • Site-wide: 76,273
• Since beginning of last month:
  • Site-wide: 80,181

A genome-scale phylogeny of Fungi; insights into early evolution, radiations, and the relationship between taxonomy and phylogeny

• Downloaded 1,658 times
• Download rankings, all-time:
  • Site-wide: 10,152
  • In evolutionary biology: 322
• Year to date:
  • Site-wide: 6,639
• Since beginning of last month:
  • Site-wide: 12,024

TET1 Modulates H4K16 Acetylation by Interacting with hMOF to Regulate Expression of DNA Repair Genes and Oncogenic Transformation

• Downloaded 1,589 times
• Download rankings, all-time:
  • Site-wide: 10,811
  • In molecular biology: 294
• Year to date:
  • Site-wide: 82,448
• Since beginning of last month:
  • Site-wide: 43,348

Organizing Pneumonia of COVID-19: Time-dependent Evolution and Outcome in CT Findings

• Downloaded 1,245 times
• Download rankings, all-time:
  • Site-wide: 15,618
  • In radiology and imaging: 33
• Year to date:
  • Site-wide: 49,269
• Since beginning of last month:
  • Site-wide: 36,864

Covalent Modification and Regulation of the Nuclear Receptor Nurr1 by a Dopamine Metabolite

• Downloaded 1,155 times
• Download rankings, all-time:
  • Site-wide: 17,441
  • In biophysics: 437
• Year to date:
  • Site-wide: 54,053
• Since beginning of last month:
  • Site-wide: 100,571

A two-stage ECG signal denoising method based on deep convolutional network

• Downloaded 1,121 times
• Download rankings, all-time:
  • Site-wide: 18,230
  • In bioengineering: 305
• Year to date:
  • Site-wide: 4,259
• Since beginning of last month:
  • Site-wide: 4,118

Cleavage of a pathogen apoplastic protein by plant subtilases activates immunity

• Downloaded 991 times
• Download rankings, all-time:
  • Site-wide: 21,775
  • In plant biology: 353
• Year to date:
  • Site-wide: 45,372
• Since beginning of last month:
  • Site-wide: 82,975

The YdiU Domain Modulates Bacterial Stress Signaling through Mn2+-dependent UMPylation

• Downloaded 931 times
• Download rankings, all-time:
  • Site-wide: 23,931
  • In biochemistry: 540
• Year to date:
  • Site-wide: 101,162
• Since beginning of last month:
  • Site-wide: 104,494

The landscape of DNA methylation associated with the transcriptomic network in laying hens and broilers generates insight into embryonic muscle development in chicken

• Downloaded 863 times
• Download rankings, all-time:
  • Site-wide: 26,580
  • In bioinformatics: 3,092
• Year to date:
  • Site-wide: 48,645
• Since beginning of last month:
  • Site-wide: 74,766

Positive feedback loop of regulating ERK phosphorylation in mESCs mediated by Etv5-Tet2-Fgfr2 axis

• Downloaded 858 times
• Download rankings, all-time:
  • Site-wide: 26,802
  • In developmental biology: 522
• Year to date:
  • Site-wide: 61,881
• Since beginning of last month:
  • Site-wide: 77,314

Molecular dating of the emergence of anaerobic rumen fungi and the impact of laterally acquired genes

• Downloaded 824 times
• Download rankings, all-time:
  • Site-wide: 28,386
  • In evolutionary biology: 1,321
• Year to date:
  • Site-wide: 77,161
• Since beginning of last month:
  • Site-wide: 59,471

N-Acetyl Cysteine Alleviates Coxsackievirus B-Induced Myocarditis by Suppressing caspase-1

• Downloaded 742 times
• Download rankings, all-time:
  • Site-wide: 32,850
  • In microbiology: 1,951
• Year to date:
  • Site-wide: 43,277
• Since beginning of last month:
  • Site-wide: 88,682

Wuhan and Hubei COVID-19 mortality analysis reveals the critical role of timely supply of medical resources

• Downloaded 704 times
• Download rankings, all-time:
  • Site-wide: 35,342
  • In epidemiology: 1,745
• Year to date:
  • Site-wide: 95,870
• Since beginning of last month:
  • Site-wide: 80,204

Negligible Risk of the COVID-19 Resurgence Caused by Work Resuming in China (outside Hubei): a Statistical Probability Study

• Downloaded 693 times
• Download rankings, all-time:
  • Site-wide: 36,093
  • In epidemiology: 1,769
• Year to date:
  • Site-wide: 86,535
• Since beginning of last month:
  • Site-wide: 110,926

Time-resolved digital immunoassay for rapid and sensitive quantitation of procalcitonin with plasmonic imaging

• Downloaded 637 times
• Download rankings, all-time:
  • Site-wide: 40,341
  • In bioengineering: 730
• Year to date:
  • Site-wide: 64,220
• Since beginning of last month:
  • Site-wide: 43,640

2019 Association of Biomolecular Resource Facilities Multi-Laboratory Data-Independent Acquisition Study

• Downloaded 594 times
• Download rankings, all-time:
  • Site-wide: 43,988
  • In bioinformatics: 4,677
• Year to date:
  • Site-wide: 6,393
• Since beginning of last month:
  • Site-wide: 41,350

T-bet+ CD11c+ B Cells Are Critical For Anti-Chromatin IgG Production In The Development Of Lupus

• Downloaded 545 times
• Download rankings, all-time:
  • Site-wide: 48,925
  • In immunology: 1,382
• Year to date:
  • Site-wide: 121,152
• Since beginning of last month:
  • Site-wide: 122,045

An overexpressed Q allele leads to increased spike density and improved processing quality

• Downloaded 544 times
• Download rankings, all-time:
  • Site-wide: 49,039
  • In genetics: 2,279
• Year to date:
  • Site-wide: 97,676
• Since beginning of last month:
  • Site-wide: 91,464

TSD: A computational tool to study the complex structural variants using PacBio targeted sequencing data

• Downloaded 530 times
• Download rankings, all-time:
  • Site-wide: 50,485
  • In bioinformatics: 5,212
• Year to date:
  • Site-wide: 131,912
• Since beginning of last month:
  • Site-wide: 125,393

A spatiotemporal translatome of mouse tissue development

• Downloaded 475 times
• Download rankings, all-time:
  • Site-wide: 57,313
  • In bioinformatics: 5,783
• Year to date:
  • Site-wide: 52,738
• Since beginning of last month:
  • Site-wide: 39,774

A pattern categorization of CT findings to predict outcome of COVID-19 pneumonia

• Downloaded 440 times
• Download rankings, all-time:
  • Site-wide: 62,125
  • In infectious diseases: 3,020
• Year to date:
  • Site-wide: 81,566
• Since beginning of last month:
  • Site-wide: 111,534

Single cell RNA sequencing reveals regulation of fetal ovary development in the monkey (Macaca fascicularis)

• Downloaded 436 times
• Download rankings, all-time:
  • Site-wide: 62,619
  • In developmental biology: 1,558
• Year to date:
  • Site-wide: 53,583
• Since beginning of last month:
  • Site-wide: 55,402

Hypercholesterolemia risk associated GPR146 is an orphan G-protein coupled receptor that regulates blood cholesterol level in human and mouse

• Downloaded 431 times
• Download rankings, all-time:
  • Site-wide: 63,496
  • In genetics: 2,912
• Year to date:
  • Site-wide: 60,463
• Since beginning of last month:
  • Site-wide: 55,686

Plasticity and the role of mass-scaling in allocation, morphology and anatomical trait responses to above and belowground resource limitation in cultivated sunflower (Helianthus annuus L.)

• Downloaded 428 times
• Download rankings, all-time:
  • Site-wide: 63,911
  • In plant biology: 1,628
• Year to date:
  • Site-wide: 49,793
• Since beginning of last month:
  • Site-wide: 33,086

Coevolution-based prediction of protein-protein interactions in polyketide biosynthetic assembly lines

• Downloaded 412 times
• Download rankings, all-time:
  • Site-wide: 66,405
  • In bioinformatics: 6,424
• Year to date:
  • Site-wide: 71,124
• Since beginning of last month:
  • Site-wide: 114,118

The LIM-Only Protein FHL2 is Involved in Autophagy to Regulate the Development of Skeletal Muscle

• Downloaded 401 times
• Download rankings, all-time:
  • Site-wide: 68,214
  • In molecular biology: 1,981
• Year to date:
  • Site-wide: 77,492
• Since beginning of last month:
  • Site-wide: 88,411

Left ventricular geometry during unloading and the end-systolic pressure volume relationship: Measurement with a modified real-time MRI-based method in normal sheep

• Downloaded 384 times
• Download rankings, all-time:
  • Site-wide: 70,944
  • In bioengineering: 1,297
• Year to date:
  • Site-wide: 115,653
• Since beginning of last month:
  • Site-wide: 132,884

Mapping fetal brain development based on automated segmentation and 4D brain atlasing

• Downloaded 363 times
• Download rankings, all-time:
  • Site-wide: 74,781
  • In neuroscience: 11,369
• Year to date:
  • Site-wide: 35,940
• Since beginning of last month:
  • Site-wide: 17,764

Dysregulation of EMT Drives the Progression to Clinically Aggressive Sarcomatoid Bladder Cancer

• Downloaded 345 times
• Download rankings, all-time:
  • Site-wide: 78,122
  • In genomics: 5,195
• Year to date:
  • Site-wide: 116,237
• Since beginning of last month:
  • Site-wide: 93,907

CD44 inhibits α-SMA gene expression via a novel G-actin/MRTF mediated pathway that requires TGFβR/p38MAPK activity in murine skin fibroblasts.

• Downloaded 309 times
• Download rankings, all-time:
  • Site-wide: 85,204
  • In cell biology: 3,962
• Year to date:
  • Site-wide: 75,599
• Since beginning of last month:
  • Site-wide: 85,167

Structural insights into the Ca 2+-dependent gating of the human mitochondrial calcium uniporter

• Downloaded 306 times
• Download rankings, all-time:
  • Site-wide: 85,969
  • In biochemistry: 2,485
• Year to date:
  • Site-wide: 117,840
• Since beginning of last month:
  • Site-wide: 127,222

Tracking and predicting the African COVID-19 pandemic

• Downloaded 293 times
• Download rankings, all-time:
  • Site-wide: 88,615
  • In infectious diseases: 3,622
• Year to date:
  • Site-wide: 30,017
• Since beginning of last month:
  • Site-wide: 38,613

Phylogenomic analyses of non-Dikarya fungi supports horizontal gene transfer driving diversification of secondary metabolism in the amphibian gastrointestinal symbiont, Basidiobolus

• Downloaded 292 times
• Download rankings, all-time:
  • Site-wide: 88,868
  • In genomics: 5,596
• Year to date:
  • Site-wide: 113,137
• Since beginning of last month:
  • Site-wide: 106,287

Differences of clinical and imaging findings in multiple generations of secondary COVID-19 infection in Xi'an, China

• Downloaded 281 times
• Download rankings, all-time:
  • Site-wide: 91,355
  • In radiology and imaging: 148
• Year to date:
  • Site-wide: 109,767
• Since beginning of last month:
  • Site-wide: 80,349

Drosophila larval epidermal cells only exhibit epidermal aging when they persist to the adult stage

• Downloaded 276 times
• Download rankings, all-time:
  • Site-wide: 92,414
  • In cell biology: 4,282
• Year to date:
  • Site-wide: 81,173
• Since beginning of last month:
  • Site-wide: 47,855

HIFα regulates developmental myelination independent of autocrine Wnt signaling

• Downloaded 260 times
• Download rankings, all-time:
  • Site-wide: 95,938
  • In neuroscience: 14,793
• Year to date:
  • Site-wide: 56,137
• Since beginning of last month:
  • Site-wide: 54,622

RNA-seq analysis of laser micro-dissected Arabidopsis thaliana leaf epidermis, mesophyll and vasculature defines tissue-specific transcriptional responses to multiple stress treatments

• Downloaded 259 times
• Download rankings, all-time:
  • Site-wide: 96,063
  • In plant biology: 2,582
• Year to date:
  • Site-wide: 43,686
• Since beginning of last month:
  • Site-wide: 70,950

Larger organ size caused by obesity is a mechanism for higher cancer risk.

• Downloaded 255 times
• Download rankings, all-time:
  • Site-wide: 96,993
  • In cancer biology: 2,931
• Year to date:
  • Site-wide: 32,545
• Since beginning of last month:
  • Site-wide: 34,666

Assessing deep learning algorithms in cis-regulatory motif finding based on genomic sequencing data

• Downloaded 252 times
• Download rankings, all-time:
  • Site-wide: 97,761
  • In bioinformatics: 8,451
• Year to date:
  • Site-wide: 37,590
• Since beginning of last month:
  • Site-wide: 32,727

Transcriptional Inactivation of TP53 and the BMP Pathway Mediates Therapy-induced Dedifferentiation and Metastasis in Prostate Cancer

• Downloaded 247 times
• Download rankings, all-time:
  • Site-wide: 98,783
  • In cancer biology: 2,988
• Year to date:
  • Site-wide: 10,460
• Since beginning of last month:
  • Site-wide: 1,355

The role of BMP6 in the proliferation and differentiation of chicken cartilage cells

• Downloaded 241 times
• Download rankings, all-time:
  • Site-wide: 100,168
  • In cell biology: 4,652
• Year to date:
  • Site-wide: 132,965
• Since beginning of last month:
  • Site-wide: 102,210

Glial type specific regulation of CNS angiogenesis by HIFα-activated different signaling pathways

• Downloaded 228 times
• Download rankings, all-time:
  • Site-wide: 103,126
  • In neuroscience: 15,914
• Year to date:
  • Site-wide: 110,236
• Since beginning of last month:
  • Site-wide: 130,450

RNF219 interacts with CCR4-NOT in regulating stem cell differentiation

• Downloaded 226 times
• Download rankings, all-time:
  • Site-wide: 103,430
  • In molecular biology: 3,073
• Year to date:
  • Site-wide: 61,803
• Since beginning of last month:
  • Site-wide: 72,540

Mutant Zp1 results in Zona Pellucida Lacking and Female Infertility in Rats and Humans

• Downloaded 207 times
• Download rankings, all-time:
  • Site-wide: 107,997
  • In genetics: 4,705
• Year to date:
  • Site-wide: 98,787
• Since beginning of last month:
  • Site-wide: 77,929

Genome-scale phylogenetic analyses confirm Olpidium as the closest living zoosporic fungus to the non-flagellated, terrestrial fungi

• Downloaded 206 times
• Download rankings, all-time:
  • Site-wide: 108,201
  • In evolutionary biology: 5,654
• Year to date:
  • Site-wide: 66,648
• Since beginning of last month:
  • Site-wide: 109,327

PBN-PVT projection modulates negative emotions in mice

• Downloaded 204 times
• Download rankings, all-time:
  • Site-wide: 108,669
  • In neuroscience: 16,744
• Year to date:
  • Site-wide: 13,604
• Since beginning of last month:
  • Site-wide: 24,677

Site-specific covalent labeling of large RNAs with nanoparticles empowered by expanded genetic alphabet transcription

• Downloaded 201 times
• Download rankings, all-time:
  • Site-wide: 109,267
  • In biophysics: 4,206
• Year to date:
  • Site-wide: 79,741
• Since beginning of last month:
  • Site-wide: 127,881

The Wnt effector TCF7l2 promotes oligodendroglial differentiation by repressing autocrine BMP4-mediated signaling

• Downloaded 193 times
• Download rankings, all-time:
  • Site-wide: 110,948
  • In neuroscience: 17,091
• Year to date:
  • Site-wide: 42,698
• Since beginning of last month:
  • Site-wide: 40,528

Phytophthora sojae effector Avr1d functions as E2 competitor and inhibits ubiquitination activity of GmPUB13 to facilitate infection

• Downloaded 182 times
• Download rankings, all-time:
  • Site-wide: 113,495
  • In microbiology: 8,477
• Year to date:
  • Site-wide: 53,533
• Since beginning of last month:
  • Site-wide: 109,270

Dicer1 is reduced in APPswe/PSEN1dE9 mice and is regulated by Nrf2

• Downloaded 169 times
• Download rankings, all-time:
  • Site-wide: 116,431
  • In neuroscience: 17,893
• Year to date:
  • Site-wide: 133,835
• Since beginning of last month:
  • Site-wide: 124,684

Dicer1 promotes Aβ clearance via blocking B2 RNA-mediated repression of apolipoprotein E

• Downloaded 168 times
• Download rankings, all-time:
  • Site-wide: 116,486
  • In neuroscience: 17,926
• Year to date:
  • Site-wide: 45,632
• Since beginning of last month:
  • Site-wide: 97,883

Individual-level and neighborhood-level factors associated with longitudinal changes in cardiometabolic measures in participants of a care coordination program

• Downloaded 164 times
• Download rankings, all-time:
  • Site-wide: 117,365
  • In primary care research: 78
• Year to date:
  • Site-wide: 18,126
• Since beginning of last month:
  • Site-wide: 13,710

Development of an electronic frailty index for predicting mortality in patients undergoing transcatheter aortic valve replacement using machine learning

• Downloaded 143 times
• Download rankings, all-time:
  • Site-wide: 121,781
  • In cardiovascular medicine: 308
• Year to date:
  • Site-wide: 40,431
• Since beginning of last month:
  • Site-wide: 46,550

The size of helical pitch is important for microtubule plus end dynamic instability

• Downloaded 134 times
• Download rankings, all-time:
  • Site-wide: 123,565
  • In cell biology: 5,707
• Year to date:
  • Site-wide: 30,075
• Since beginning of last month:
  • Site-wide: 64,626

riboCIRC: a comprehensive database of translatable circRNAs

• Downloaded 115 times
• Download rankings, all-time:
  • Site-wide: 127,356
  • In bioinformatics: 10,123
• Year to date:
  • Site-wide: 27,568
• Since beginning of last month:
  • Site-wide: 64,400

Decoding regulatory specificity of human ribosomal proteins on global gene expression

• Downloaded 93 times
• Download rankings, all-time:
  • Site-wide: 131,272
  • In cell biology: 6,008
• Year to date:
  • Site-wide: 34,542
• Since beginning of last month:
  • Site-wide: 21,188

Rationale, protocol and baseline characteristics of the metabolome, microbiome, and dietary salt intervention study (MetaSalt)

• Downloaded 92 times
• Download rankings, all-time:
  • Site-wide: 131,417
  • In epidemiology: 5,323
• Year to date:
  • Site-wide: 35,108
• Since beginning of last month:
  • Site-wide: 56,734

Effectiveness of Joint Species Distribution Models in the Presence of Imperfect Detection

• Downloaded 82 times
• Download rankings, all-time:
  • Site-wide: 132,919
  • In ecology: 4,955
• Year to date:
  • Site-wide: 39,024
• Since beginning of last month:
  • Site-wide: 46,188

Blocking of EGFR Signaling is a Latent Strategy for the Improvement of Prognosis of HPV Induced Cancer

• Downloaded 76 times
• Download rankings, all-time:
  • Site-wide: 133,805
  • In microbiology: 10,309
• Year to date:
  • Site-wide: 95,473
• Since beginning of last month:
  • Site-wide: 83,428