Author: Yan Wang

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Preprints

Fatty acid binding protein 1 and fatty acid synthetase overexpression have differential effects on collagen III and cross-linking in Zongdihua pig tissues

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Epidemiological characteristics and transmission dynamics of the outbreak caused by the SARS-CoV-2 Omicron variant in Shanghai, China: a descriptive study

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Age profile of susceptibility, mixing, and social distancing shape the dynamics of the novel coronavirus disease 2019 outbreak in China

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Prevalence and Risk Factors for Acute Posttraumatic Stress Disorder during the COVID-19 Outbreak

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Detection of 2019 novel coronavirus in semen and testicular biopsy specimen of COVID-19 patients

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Evolving epidemiology of novel coronavirus diseases 2019 and possible interruption of local transmission outside Hubei Province in China: a descriptive and modeling study

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Infectivity, susceptibility, and risk factors associated with SARS-CoV-2 transmission under intensive contact tracing in Hunan, China

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MECAT: an ultra-fast mapping, error correction and de novo assembly tool for single-molecule sequencing reads

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Dual midbrain and forebrain origins of thalamic inhibitory interneurons

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Case fatality risk of novel coronavirus diseases 2019 in China

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High risk of infection caused posttraumatic stress symptoms in individuals with poor sleep quality: A study on influence of coronavirus disease (COVID-19) in China

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  • In psychiatry and clinical psychology: 39
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A genome-scale phylogeny of Fungi; insights into early evolution, radiations, and the relationship between taxonomy and phylogeny

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  • Site-wide: 10,331
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Transmission heterogeneities, kinetics, and controllability of SARS-CoV-2

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A statistical framework for mapping risk genes from de novo mutations in whole-genome sequencing studies

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A two-stage ECG signal denoising method based on deep convolutional network

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Simulating and Forecasting the Cumulative Confirmed Cases of SARS-CoV-2 in China by Boltzmann Function-based Regression Analyses

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TET1 Modulates H4K16 Acetylation by Interacting with hMOF to Regulate Expression of DNA Repair Genes and Oncogenic Transformation

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Organizing Pneumonia of COVID-19: Time-dependent Evolution and Outcome in CT Findings

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Covalent Modification and Regulation of the Nuclear Receptor Nurr1 by a Dopamine Metabolite

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N-Acetyl Cysteine Alleviates Coxsackievirus B-Induced Myocarditis by Suppressing caspase-1

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  • Site-wide: 26,446
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The landscape of DNA methylation associated with the transcriptomic network in laying hens and broilers generates insight into embryonic muscle development in chicken

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Cleavage of a pathogen apoplastic protein by plant subtilases activates immunity

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  • Site-wide: 28,185
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The YdiU Domain Modulates Bacterial Stress Signaling through Mn2+-dependent UMPylation

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Positive feedback loop of regulating ERK phosphorylation in mESCs mediated by Etv5-Tet2-Fgfr2 axis

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  • Site-wide: 34,018
  • In developmental biology: 616
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Transcriptional Inactivation of TP53 and the BMP Pathway Mediates Therapy-induced Dedifferentiation and Metastasis in Prostate Cancer

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  • Site-wide: 36,323
  • In cancer biology: 1,033
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Molecular dating of the emergence of anaerobic rumen fungi and the impact of laterally acquired genes

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  • Site-wide: 36,351
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Wuhan and Hubei COVID-19 mortality analysis reveals the critical role of timely supply of medical resources

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  • Site-wide: 46,140
  • In epidemiology: 2,249
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Negligible Risk of the COVID-19 Resurgence Caused by Work Resuming in China (outside Hubei): a Statistical Probability Study

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  • Site-wide: 48,672
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Integrative molecular and clinical profiling of acral melanoma identifies LZTR1 as a key tumor promoter and therapeutic target

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Time-resolved digital immunoassay for rapid and sensitive quantitation of procalcitonin with plasmonic imaging

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CNS antigen-specific control of early B-lineage development in the meninges

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  • Site-wide: 49,665
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2019 Association of Biomolecular Resource Facilities Multi-Laboratory Data-Independent Acquisition Study

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  • Site-wide: 53,332
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  • Site-wide: 153,879

PBN-PVT projection modulates negative affective states in mice

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Plasticity and the role of mass-scaling in allocation, morphology and anatomical trait responses to above and belowground resource limitation in cultivated sunflower (Helianthus annuus L.)

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A spatiotemporal translatome of mouse tissue development

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T-bet+ CD11c+ B Cells Are Critical For Anti-Chromatin IgG Production In The Development Of Lupus

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An overexpressed Q allele leads to increased spike density and improved processing quality

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TSD: A computational tool to study the complex structural variants using PacBio targeted sequencing data

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Assessing the feasibility of sustaining SARS-CoV-2 local containment in China in the era of highly transmissible variants

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  • Site-wide: 73,600
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Earliest evidence for frugivory and seed dispersal by birds

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Tracking and predicting the African COVID-19 pandemic

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A pattern categorization of CT findings to predict outcome of COVID-19 pneumonia

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Single cell RNA sequencing reveals regulation of fetal ovary development in the monkey (Macaca fascicularis)

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Mapping fetal brain development based on automated segmentation and 4D brain atlasing

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RNA-seq analysis of laser micro-dissected Arabidopsis thaliana leaf epidermis, mesophyll and vasculature defines tissue-specific transcriptional responses to multiple stress treatments

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Hypercholesterolemia risk associated GPR146 is an orphan G-protein coupled receptor that regulates blood cholesterol level in human and mouse

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Left ventricular geometry during unloading and the end-systolic pressure volume relationship: Measurement with a modified real-time MRI-based method in normal sheep

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Role of PARP1 in oligodendrocyte differentiation during developmental myelination and remyelination after myelin damage

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Coevolution-based prediction of protein-protein interactions in polyketide biosynthetic assembly lines

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The LIM-Only Protein FHL2 is Involved in Autophagy to Regulate the Development of Skeletal Muscle

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HIFα regulates developmental myelination independent of autocrine Wnt signaling

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Larger organ size caused by obesity is a mechanism for higher cancer risk.

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Structural insights into the Ca 2+-dependent gating of the human mitochondrial calcium uniporter

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CD44 inhibits α-SMA gene expression via a novel G-actin/MRTF mediated pathway that requires TGFβR/p38MAPK activity in murine skin fibroblasts.

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Dysregulation of EMT Drives the Progression to Clinically Aggressive Sarcomatoid Bladder Cancer

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Differences of clinical and imaging findings in multiple generations of secondary COVID-19 infection in Xi'an, China

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Assessing deep learning algorithms in cis-regulatory motif finding based on genomic sequencing data

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Kaposi's Sarcoma-associated Herpesvirus vFLIP Promotes MEndT to Generate Hybrid M/E State for Tumorigenesis

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Drosophila larval epidermal cells only exhibit epidermal aging when they persist to the adult stage

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Decoding regulatory specificity of human ribosomal proteins

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Phylogenomic analyses of non-Dikarya fungi supports horizontal gene transfer driving diversification of secondary metabolism in the amphibian gastrointestinal symbiont, Basidiobolus

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SARS-CoV-2 Exploits Sexually Dimorphic and Adaptive IFN and TNFa Signaling to Gain Entry into Alveolar Epithelium

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RNF219 interacts with CCR4-NOT in regulating stem cell differentiation

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The role of BMP6 in the proliferation and differentiation of chicken cartilage cells

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The Wnt effector TCF7l2 promotes oligodendroglial differentiation by repressing autocrine BMP4-mediated signaling

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Mutant Zp1 results in Zona Pellucida Lacking and Female Infertility in Rats and Humans

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Rationale, protocol and baseline characteristics of the metabolome, microbiome, and dietary salt intervention study (MetaSalt)

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Site-specific covalent labeling of large RNAs with nanoparticles empowered by expanded genetic alphabet transcription

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Development of an electronic frailty index for predicting mortality in patients undergoing transcatheter aortic valve replacement using machine learning

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Liver-derived cell lines from cavefish Astyanax mexicanus as an in vitro model for studying metabolic adaptation

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Glial type specific regulation of CNS angiogenesis by HIFα-activated different signaling pathways

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Phytophthora sojae effector Avr1d functions as E2 competitor and inhibits ubiquitination activity of GmPUB13 to facilitate infection

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Genome-scale phylogenetic analyses confirm Olpidium as the closest living zoosporic fungus to the non-flagellated, terrestrial fungi

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Individual-level and neighborhood-level factors associated with longitudinal changes in cardiometabolic measures in participants of a care coordination program

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Tree-based automated machine learning to predict biogas production for anaerobic co-digestion of organic waste

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Mutations in PIKFYVE cause autosomal dominant congenital cataract

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The size of helical pitch is important for microtubule plus end dynamic instability

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Dicer1 is reduced in APPswe/PSEN1dE9 mice and is regulated by Nrf2

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Activin B Promotes the Initiation and Progression of Liver Fibrosis

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Pvr and downstream signaling factors are required for spreading of Drosophila hemocytes at larval wound sites

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Effectiveness of Joint Species Distribution Models in the Presence of Imperfect Detection

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Dicer1 promotes Aβ clearance via blocking B2 RNA-mediated repression of apolipoprotein E

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  • Site-wide: 170,420

Plant-on-Chip: core morphogenesis processes in the tiny plant Wolffia australiana

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  • Site-wide: 155,804
  • In plant biology: None
• Year to date:
  • Site-wide: 15,030
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  • Site-wide: 18,376

riboCIRC: a comprehensive database of translatable circRNAs

• Downloaded 220 times
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  • Site-wide: 161,563
  • In bioinformatics: 11,755
• Year to date:
  • Site-wide: 126,137
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  • Site-wide: 166,994

Large-scale characterisation of the pregnancy vaginal microbiome and sialidase activity in a low-risk Chinese population

• Downloaded 218 times
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  • Site-wide: 162,233
  • In systems biology: 3,191
• Year to date:
  • Site-wide: 90,697
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  • Site-wide: 69,344

Visualization of SpoVAEa protein dynamics in dormant spores of Bacillus cereus and dynamic changes in their germinosomes and SpoVAEa during germination

• Downloaded 196 times
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  • Site-wide: 167,845
  • In microbiology: 13,255
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  • Site-wide: 20,297
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  • Site-wide: 57,955

Geraniol Enhances Inhibitory Inputs to Paraventricular Thalamic Nucleus and Induces Sedation in Mice

• Downloaded 195 times
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  • Site-wide: 168,100
  • In neuroscience: 23,903
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  • Site-wide: 69,038

Kaposi's Sarcoma-associated Herpesvirus Promotes Mesenchymal-to-Endothelial Transition by Resolving the Bivalent Chromatin of PROX1 Gene

• Downloaded 194 times
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  • Site-wide: 168,380
  • In microbiology: 11,882
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  • Site-wide: 135,893

Blocking of EGFR Signaling is a Latent Strategy for the Improvement of Prognosis of HPV Induced Cancer

• Downloaded 190 times
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  • Site-wide: 169,455
  • In microbiology: 12,018
• Year to date:
  • Site-wide: 140,393
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  • Site-wide: 128,068

Proteogenomics analysis to identify acquired resistance-specific alterations in melanoma PDXs on MAPKi therapy

• Downloaded 187 times
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  • Site-wide: 170,086
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• Year to date:
  • Site-wide: 21,708
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  • Site-wide: 83,328

EBV LMP1-activated mTORC1 and mTORC2 Coordinately Promote Nasopharyngeal Cancer Stem Cell Properties

• Downloaded 167 times
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  • Site-wide: 174,727
  • In cancer biology: 5,179
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  • Site-wide: 39,908
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  • Site-wide: 166,863

Engineered neuron-targeting, placental mesenchymal stromal cell-derived extracellular vesicles for in utero treatment of myelomeningocele

• Downloaded 134 times
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  • Site-wide: 181,012
  • In bioengineering: 3,714
• Year to date:
  • Site-wide: 71,684
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  • Site-wide: 124,206

Serum Amyloid A promotes Acetaminophen-induced liverinjury by damaging sinusoidal endothelial cell and exacerbating platelet aggregation in liver

• Downloaded 125 times
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  • Site-wide: 182,431
  • In pharmacology and toxicology: 1,517
• Year to date:
  • Site-wide: 72,675
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  • Site-wide: 134,895

The Insulin receptor regulates the persistence of mechanical nociceptive sensitization in flies and mice

• Downloaded 120 times
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  • Site-wide: 183,149
  • In neuroscience: None
• Year to date:
  • Site-wide: 38,318
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  • Site-wide: 53,917

Keap1 recognizes EIAV early accessory protein Rev to promote antiviral defense

• Downloaded 97 times
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  • Site-wide: 186,151
  • In microbiology: 13,431
• Year to date:
  • Site-wide: 144,348
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  • Site-wide: 155,508

Species-specific bacterial detector for fast pathogen diagnosis of severe pneumonia patients in the intensive care unit

• Downloaded 93 times
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  • Site-wide: 186,663
  • In intensive care and critical care medicine: None
• Year to date:
  • Site-wide: 50,775
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  • Site-wide: 83,408

Characterization of two conserved cell death elicitor families from the Dothideomycete fungal pathogens Dothistroma septosporum and Fulvia fulva (syn. Cladosporium fulvum)

• Downloaded 64 times
• Download rankings, all-time:
  • Site-wide: 189,230
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• Year to date:
  • Site-wide: 72,294
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  • Site-wide: 18,374