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Author: Herbert Levine

Rankings

  • All-time downloads: 26,589 (rank: 8,221 (tie) )
  • Categories:
    • bioinformatics: 293 (rank: 38,906 (tie) )
    • biophysics: 5,185 (rank: 494 )
    • cancer biology: 15,439 (rank: 109 )
    • developmental biology: 521 (rank: 12,020 (tie) )
    • evolutionary biology: 419 (rank: 18,647 (tie) )
    • neuroscience: 579 (rank: 49,246 (tie) )
    • systems biology: 4,153 (rank: 1,065 )

Downloads per author, site-wide

Preprints

EMT and MET: necessary or permissive for metastasis?

cancer biology more details view paper
  • Downloaded 1,269 times
  • Download rankings, all-time:
    • Site-wide: 19,792
    • In cancer biology: 456
  • Year to date:
    • Site-wide: 80,630
  • Since beginning of last month:
    • Site-wide: 145,195

NRF2 activates a partial Epithelial-Mesenchymal Transition and is maximally present in a hybrid Epithelial/Mesenchymal phenotype

cancer biology more details view paper
  • Downloaded 1,235 times
  • Download rankings, all-time:
    • Site-wide: 20,601
    • In cancer biology: 478
  • Year to date:
    • Site-wide: 90,441
  • Since beginning of last month:
    • Site-wide: 126,143

Infiltration of CD8+ T cells into tumor-cell clusters in Triple Negative Breast Cancer

cancer biology more details view paper
  • Downloaded 1,039 times
  • Download rankings, all-time:
    • Site-wide: 26,846
    • In cancer biology: 679
  • Year to date:
    • Site-wide: 92,433
  • Since beginning of last month:
    • Site-wide: 146,270

Suppressing chemoresistance in lung cancer via dynamic phenotypic switching and intermittent therapy

cancer biology more details view paper
  • Downloaded 944 times
  • Download rankings, all-time:
    • Site-wide: 30,845
    • In cancer biology: 793
  • Year to date:
    • Site-wide: 35,948
  • Since beginning of last month:
    • Site-wide: 25,518

Testing the Gene Expression Classification of the EMT Spectrum

systems biology more details view paper
  • Downloaded 907 times
  • Download rankings, all-time:
    • Site-wide: 32,780
    • In systems biology: 657
  • Year to date:
    • Site-wide: 93,466
  • Since beginning of last month:
    • Site-wide: 79,048

Stiffness Sensing and Cell Motility: Durotaxis and Contact Guidance

biophysics more details view paper
  • Downloaded 903 times
  • Download rankings, all-time:
    • Site-wide: 32,961
    • In biophysics: 993
  • Year to date:
    • Site-wide: 95,598
  • Since beginning of last month:
    • Site-wide: 99,384

Epithelial-mesenchymal plasticity: How have quantitative mathematical models helped improve our understanding?

cancer biology more details view paper
  • Downloaded 890 times
  • Download rankings, all-time:
    • Site-wide: 33,674
    • In cancer biology: 896
  • Year to date:
    • Site-wide: 139,255
  • Since beginning of last month:
    • Site-wide: 134,500

A Mechanism for Epithelial-Mesenchymal Heterogeneity in a Population of Cancer Cells

cancer biology more details view paper
  • Downloaded 776 times
  • Download rankings, all-time:
    • Site-wide: 40,983
    • In cancer biology: 1,118
  • Year to date:
    • Site-wide: 131,370
  • Since beginning of last month:
    • Site-wide: 138,707

E-cadherin represses anchorage-independent growth in sarcomas through both signaling and mechanical mechanisms

cancer biology more details view paper
  • Downloaded 771 times
  • Download rankings, all-time:
    • Site-wide: 41,386
    • In cancer biology: 1,139
  • Year to date:
    • Site-wide: 113,745
  • Since beginning of last month:
    • Site-wide: 139,644

Rapid Assessment of T-Cell Receptor Specificity of the Immune Repertoire

biophysics more details view paper
  • Downloaded 768 times
  • Download rankings, all-time:
    • Site-wide: 41,647
    • In biophysics: 1,326
  • Year to date:
    • Site-wide: 23,401
  • Since beginning of last month:
    • Site-wide: 8,816

Inflammatory Breast Cancer: a model for investigating cluster-based dissemination

cancer biology more details view paper
  • Downloaded 763 times
  • Download rankings, all-time:
    • Site-wide: 42,056
    • In cancer biology: 1,162
  • Year to date:
    • Site-wide: 138,224
  • Since beginning of last month:
    • Site-wide: 125,241

Comparative study of transcriptomics-based scoring metrics for the epithelial-hybrid-mesenchymal spectrum

cancer biology more details view paper
  • Downloaded 744 times
  • Download rankings, all-time:
    • Site-wide: 43,604
    • In cancer biology: 1,202
  • Year to date:
    • Site-wide: 37,311
  • Since beginning of last month:
    • Site-wide: 96,565

On the mechanism of long-range alignment order of fibroblasts

biophysics more details view paper
  • Downloaded 735 times
  • Download rankings, all-time:
    • Site-wide: 44,270
    • In biophysics: 1,433
  • Year to date:
    • Site-wide: 144,523
  • Since beginning of last month:
    • Site-wide: 138,567

Interrogating the Topological Robustness of Gene Regulatory Circuits

systems biology more details view paper
  • Downloaded 687 times
  • Download rankings, all-time:
    • Site-wide: 48,622
    • In systems biology: 1,039
  • Year to date:
    • Site-wide: 154,531
  • Since beginning of last month:
    • Site-wide: 142,003

Towards understanding cancer stem cell heterogeneity in the tumor microenvironment

cancer biology more details view paper
  • Downloaded 596 times
  • Download rankings, all-time:
    • Site-wide: 58,758
    • In cancer biology: 1,695
  • Year to date:
    • Site-wide: 147,909
  • Since beginning of last month:
    • Site-wide: 143,882

Properties of Gene Expression and Chromatin Structure with Mechanically Regulated Transcription

biophysics more details view paper
  • Downloaded 592 times
  • Download rankings, all-time:
    • Site-wide: 59,339
    • In biophysics: 2,004
  • Year to date:
    • Site-wide: 160,092
  • Since beginning of last month:
    • Site-wide: 146,486

Calpain-2 regulates hypoxia/HIF-induced amoeboid reprogramming and metastasis

cancer biology more details view paper
  • Downloaded 590 times
  • Download rankings, all-time:
    • Site-wide: 59,483
    • In cancer biology: 1,716
  • Year to date:
    • Site-wide: 48,381
  • Since beginning of last month:
    • Site-wide: 40,030

Computational modeling of the crosstalk between macrophage polarization and tumor cell plasticity in the tumor microenvironment

systems biology more details view paper
  • Downloaded 590 times
  • Download rankings, all-time:
    • Site-wide: 59,579
    • In systems biology: 1,303
  • Year to date:
    • Site-wide: 149,925
  • Since beginning of last month:
    • Site-wide: 154,427

Presynaptic Endoplasmic Reticulum Contributes Crucially to Short-term Plasticity in Small Hippocampal Synapses

neuroscience more details view paper
  • Downloaded 579 times
  • Download rankings, all-time:
    • Site-wide: 60,975
    • In neuroscience: 8,757
  • Year to date:
    • Site-wide: 109,237
  • Since beginning of last month:
    • Site-wide: 99,621

PAGE4 and Conformational Switching: Insights from Molecular Dynamics Simulations and Implications for Prostate Cancer

biophysics more details view paper
  • Downloaded 576 times
  • Download rankings, all-time:
    • Site-wide: 61,392
    • In biophysics: 2,103
  • Year to date:
    • Site-wide: 124,859
  • Since beginning of last month:
    • Site-wide: 99,435

A possible role for epigenetic feedback regulation in the dynamics of the Epithelial-Mesenchymal Transition (EMT)

biophysics more details view paper
  • Downloaded 573 times
  • Download rankings, all-time:
    • Site-wide: 61,705
    • In biophysics: 2,114
  • Year to date:
    • Site-wide: 118,133
  • Since beginning of last month:
    • Site-wide: 141,706

Interconnected feedback loops among ESRP1, HAS2, and CD44 regulate epithelial-mesenchymal plasticity in cancer

cancer biology more details view paper
  • Downloaded 571 times
  • Download rankings, all-time:
    • Site-wide: 61,989
    • In cancer biology: 1,792
  • Year to date:
    • Site-wide: 152,711
  • Since beginning of last month:
    • Site-wide: 153,791

Towards Decoding the Metabolic Plasticity in Cancer: Coupling of Gene Regulation and Metabolic Pathways

systems biology more details view paper
  • Downloaded 546 times
  • Download rankings, all-time:
    • Site-wide: 65,502
    • In systems biology: 1,452
  • Year to date:
    • Site-wide: 145,508
  • Since beginning of last month:
    • Site-wide: 119,086

Cluster Size Distribution of Cells Disseminating from a Primary Tumor

cancer biology more details view paper
  • Downloaded 540 times
  • Download rankings, all-time:
    • Site-wide: 66,413
    • In cancer biology: 1,922
  • Year to date:
    • Site-wide: 13,806
  • Since beginning of last month:
    • Site-wide: 2,092

Pericytes enable effective angiogenesis in the presence of pro inflammatory signals

developmental biology more details view paper
  • Downloaded 521 times
  • Download rankings, all-time:
    • Site-wide: 69,251
    • In developmental biology: 1,736
  • Year to date:
    • Site-wide: 142,210
  • Since beginning of last month:
    • Site-wide: 145,484

DNA supercoiling-mediated collective behavior of co-transcribing RNA polymerases

biophysics more details view paper
  • Downloaded 511 times
  • Download rankings, all-time:
    • Site-wide: 70,773
    • In biophysics: 2,517
  • Year to date:
    • Site-wide: 15,021
  • Since beginning of last month:
    • Site-wide: 6,053

Drug-tolerant idling melanoma cells exhibit theory-predicted metabolic low-low phenotype

systems biology more details view paper
  • Downloaded 498 times
  • Download rankings, all-time:
    • Site-wide: 73,007
    • In systems biology: 1,618
  • Year to date:
    • Site-wide: 131,884
  • Since beginning of last month:
    • Site-wide: 107,293

RACIPE: A computational tool for Modeling Gene Regulatory Circuits using Randomization

systems biology more details view paper
  • Downloaded 492 times
  • Download rankings, all-time:
    • Site-wide: 73,893
    • In systems biology: 1,650
  • Year to date:
    • Site-wide: 147,332
  • Since beginning of last month:
    • Site-wide: 153,215

A mechanism-based computational model to capture the interconnections among epithelial-mesenchymal transition, cancer stem cells and Notch-Jagged signaling

cancer biology more details view paper
  • Downloaded 476 times
  • Download rankings, all-time:
    • Site-wide: 76,737
    • In cancer biology: 2,254
  • Year to date:
    • Site-wide: 149,484
  • Since beginning of last month:
    • Site-wide: 141,138

Ordered Hexagonal Patterns via Notch-Delta Signaling

biophysics more details view paper
  • Downloaded 455 times
  • Download rankings, all-time:
    • Site-wide: 80,578
    • In biophysics: 2,928
  • Year to date:
    • Site-wide: 132,649
  • Since beginning of last month:
    • Site-wide: 100,013

Fractal dimension, occupancy and hotspot analyses of B cell spatial distribution predict clinical outcome in breast cancer

cancer biology more details view paper
  • Downloaded 437 times
  • Download rankings, all-time:
    • Site-wide: 84,107
    • In cancer biology: 2,478
  • Year to date:
    • Site-wide: 85,736
  • Since beginning of last month:
    • Site-wide: 79,203

Anticipating critical transitions in epithelial-hybrid-mesenchymal cell-fate determination

systems biology more details view paper
  • Downloaded 433 times
  • Download rankings, all-time:
    • Site-wide: 84,893
    • In systems biology: 1,888
  • Year to date:
    • Site-wide: 151,204
  • Since beginning of last month:
    • Site-wide: 148,166

Immunosuppressive traits of the hybrid epithelial/mesenchymal phenotype

cancer biology more details view paper
  • Downloaded 430 times
  • Download rankings, all-time:
    • Site-wide: 85,354
    • In cancer biology: 2,536
  • Year to date:
    • Site-wide: 19,667
  • Since beginning of last month:
    • Site-wide: 17,774

Sustained Co-evolution in a Stochastic Model of the Cancer-Immune Interaction

evolutionary biology more details view paper
  • Downloaded 419 times
  • Download rankings, all-time:
    • Site-wide: 87,719
    • In evolutionary biology: 4,415
  • Year to date:
    • Site-wide: 156,594
  • Since beginning of last month:
    • Site-wide: 149,327

A Mechanistic Modeling Framework Reveals the Key Principles Underlying Tumor Metabolism

cancer biology more details view paper
  • Downloaded 413 times
  • Download rankings, all-time:
    • Site-wide: 88,931
    • In cancer biology: 2,655
  • Year to date:
    • Site-wide: 20,904
  • Since beginning of last month:
    • Site-wide: 69,613

Distinguishing Mechanisms Underlying EMT Tristability

cancer biology more details view paper
  • Downloaded 407 times
  • Download rankings, all-time:
    • Site-wide: 90,148
    • In cancer biology: 2,697
  • Year to date:
    • Site-wide: 136,972
  • Since beginning of last month:
    • Site-wide: 109,376

Numb prevents a complete EMT by modulating Notch signalling

cancer biology more details view paper
  • Downloaded 407 times
  • Download rankings, all-time:
    • Site-wide: 90,144
    • In cancer biology: 2,699
  • Year to date:
    • Site-wide: 152,728
  • Since beginning of last month:
    • Site-wide: 148,672

Nrf2 regulates collective cancer migration by modulating the hybrid epithelial/mesenchymal phenotype

cancer biology more details view paper
  • Downloaded 385 times
  • Download rankings, all-time:
    • Site-wide: 94,953
    • In cancer biology: 2,854
  • Year to date:
    • Site-wide: 23,320
  • Since beginning of last month:
    • Site-wide: 33,487

Targeting the Id1-Kif11-Aurka axis in triple negative breast cancer using combination therapy

cancer biology more details view paper
  • Downloaded 353 times
  • Download rankings, all-time:
    • Site-wide: 102,398
    • In cancer biology: 3,101
  • Year to date:
    • Site-wide: 126,415
  • Since beginning of last month:
    • Site-wide: 107,724

Modularity of the metabolic gene network as a prognostic biomarker for hepatocellular carcinoma

cancer biology more details view paper
  • Downloaded 326 times
  • Download rankings, all-time:
    • Site-wide: 109,164
    • In cancer biology: 3,323
  • Year to date:
    • Site-wide: 162,453
  • Since beginning of last month:
    • Site-wide: 160,680

Transcriptomic-based quantification of the epithelial-hybrid-mesenchymal spectrum across biological contexts

bioinformatics more details view paper
  • Downloaded 293 times
  • Download rankings, all-time:
    • Site-wide: 117,627
    • In bioinformatics: 9,619
  • Year to date:
    • Site-wide: 34,641
  • Since beginning of last month:
    • Site-wide: 8,394

Analysis of hierarchical organization in gene expression networks reveals underlying principles of collective tumor cell dissemination and metastatic aggressiveness of inflammatory breast cancer

cancer biology more details view paper
  • Downloaded 292 times
  • Download rankings, all-time:
    • Site-wide: 117,956
    • In cancer biology: 3,579
  • Year to date:
    • Site-wide: 163,590
  • Since beginning of last month:
    • Site-wide: 161,710

Epigenetic feedback and stochastic partitioning during cell division can drive resistance to EMT

cancer biology more details view paper
  • Downloaded 292 times
  • Download rankings, all-time:
    • Site-wide: 117,852
    • In cancer biology: 3,589
  • Year to date:
    • Site-wide: 141,573
  • Since beginning of last month:
    • Site-wide: 150,242

Gene expression profiles of inflammatory breast cancer reveal high heterogeneity across the epithelial-hybrid-mesenchymal spectrum

cancer biology more details view paper
  • Downloaded 290 times
  • Download rankings, all-time:
    • Site-wide: 118,239
    • In cancer biology: 3,603
  • Year to date:
    • Site-wide: 92,232
  • Since beginning of last month:
    • Site-wide: 84,421

A theoretical approach to coupling the epithelial-mesenchymal transition (EMT) to extracellular matrix (ECM) stiffness via LOXL2

cancer biology more details view paper
  • Downloaded 203 times
  • Download rankings, all-time:
    • Site-wide: 140,826
    • In cancer biology: 4,335
  • Year to date:
    • Site-wide: 55,842
  • Since beginning of last month:
    • Site-wide: 82,124

Three-dimensional Cancer Cell Migration Directed by Dual Mechanochemical Guidance

biophysics more details view paper
  • Downloaded 72 times
  • Download rankings, all-time:
    • Site-wide: 162,009
    • In biophysics: 6,238
  • Year to date:
    • Site-wide: 137,269
  • Since beginning of last month:
    • Site-wide: 26,010

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