Rxivist logo

Rxivist combines preprints from bioRxiv with data from Twitter to help you find the papers being discussed in your field. Currently indexing 52,519 bioRxiv papers from 243,473 authors.

Author: George M Church

Rankings

  • All-time downloads: 131,469 (rank: 35 out of 243,473)
  • Categories:
    • biochemistry: 2,581 (rank: 129 out of 8,471)
    • bioengineering: 3,776 (rank: 85 out of 5,437)
    • cell biology: 18,268 (rank: 2 out of 15,243)
    • evolutionary biology: 747 (rank: 3,762 (tie) out of 13,528)
    • genetics: 1,955 (rank: 4,768 (tie) out of 23,659)
    • genomics: 27,795 (rank: 182 out of 28,107)
    • immunology: 7,497 (rank: 51 (tie) out of 9,701)
    • molecular biology: 2,673 (rank: 250 out of 10,300)
    • neuroscience: 6,506 (rank: 599 (tie) out of 37,452)
    • synthetic biology: 58,475 (rank: 1 out of 2,239)
    • systems biology: 1,196 (rank: 1,119 out of 7,239)

Downloads per author, site-wide

Preprints

Recording temporal data onto DNA with minutes resolution

synthetic biology more details view paper

No bioRxiv download data for this paper yet.

Vibrio natriegens, a new genomic powerhouse

genomics more details view paper
  • Downloaded 14,271 times
  • Download rankings, all-time:
    • Site-wide: 39 out of 52,519
    • In genomics: 12 out of 3,756
  • Year to date:
    • Site-wide: 344 out of 52,519
  • Since beginning of last month:
    • Site-wide: 450 out of 52,519

Inter-homologue repair in fertilized human eggs?

cell biology more details view paper
  • Downloaded 9,790 times
  • Download rankings, all-time:
    • Site-wide: 93 out of 52,519
    • In cell biology: 4 out of 2,472
  • Year to date:
    • Site-wide: 11,336 out of 52,519
  • Since beginning of last month:
    • Site-wide: 13,030 out of 52,519

RNA-guided gene drives can efficiently and reversibly bias inheritance in wild yeast

synthetic biology more details view paper
  • Downloaded 6,858 times
  • Download rankings, all-time:
    • Site-wide: 181 out of 52,519
    • In synthetic biology: 3 out of 504
  • Year to date:
    • Site-wide: 12,595 out of 52,519
  • Since beginning of last month:
    • Site-wide: 21,808 out of 52,519

Tumor-infiltrating immune repertoires captured by single-cell barcoding in emulsion

immunology more details view paper
  • Downloaded 5,944 times
  • Download rankings, all-time:
    • Site-wide: 232 out of 52,519
    • In immunology: 4 out of 1,212
  • Year to date:
    • Site-wide: 3,219 out of 52,519
  • Since beginning of last month:
    • Site-wide: 4,706 out of 52,519

Conneconomics: The Economics of Dense, Large-Scale, High-Resolution Neural Connectomics

neuroscience more details view paper
  • Downloaded 5,876 times
  • Download rankings, all-time:
    • Site-wide: 239 out of 52,519
    • In neuroscience: 35 out of 9,207
  • Year to date:
    • Site-wide: 4,961 out of 52,519
  • Since beginning of last month:
    • Site-wide: 7,201 out of 52,519

Rapidly evolving homing CRISPR barcodes

synthetic biology more details view paper
  • Downloaded 5,729 times
  • Download rankings, all-time:
    • Site-wide: 252 out of 52,519
    • In synthetic biology: 5 out of 504
  • Year to date:
    • Site-wide: 14,908 out of 52,519
  • Since beginning of last month:
    • Site-wide: 14,615 out of 52,519

Extensive sequencing of seven human genomes to characterize benchmark reference materials

genomics more details view paper
  • Downloaded 5,641 times
  • Download rankings, all-time:
    • Site-wide: 260 out of 52,519
    • In genomics: 72 out of 3,756
  • Year to date:
    • Site-wide: 19,107 out of 52,519
  • Since beginning of last month:
    • Site-wide: 17,358 out of 52,519

Highly-efficient Cas9-mediated transcriptional programming

synthetic biology more details view paper
  • Downloaded 5,430 times
  • Download rankings, all-time:
    • Site-wide: 283 out of 52,519
    • In synthetic biology: 6 out of 504
  • Year to date:
    • Site-wide: 16,067 out of 52,519
  • Since beginning of last month:
    • Site-wide: 16,352 out of 52,519

Daisy-chain gene drives for the alteration of local populations

synthetic biology more details view paper
  • Downloaded 4,885 times
  • Download rankings, all-time:
    • Site-wide: 346 out of 52,519
    • In synthetic biology: 8 out of 504
  • Year to date:
    • Site-wide: 1,399 out of 52,519
  • Since beginning of last month:
    • Site-wide: 17,698 out of 52,519

Enabling large-scale genome editing by reducing DNA nicking

synthetic biology more details view paper
  • Downloaded 4,507 times
  • Download rankings, all-time:
    • Site-wide: 403 out of 52,519
    • In synthetic biology: 9 out of 504
  • Year to date:
    • Site-wide: 37 out of 52,519
  • Since beginning of last month:
    • Site-wide: 393 out of 52,519

CasFinder: Flexible algorithm for identifying specific Cas9 targets in genomes

genomics more details view paper
  • Downloaded 4,257 times
  • Download rankings, all-time:
    • Site-wide: 457 out of 52,519
    • In genomics: 125 out of 3,756
  • Year to date:
    • Site-wide: 7,860 out of 52,519
  • Since beginning of last month:
    • Site-wide: 6,974 out of 52,519

Toward machine-guided design of proteins

synthetic biology more details view paper
  • Downloaded 3,898 times
  • Download rankings, all-time:
    • Site-wide: 545 out of 52,519
    • In synthetic biology: 10 out of 504
  • Year to date:
    • Site-wide: 361 out of 52,519
  • Since beginning of last month:
    • Site-wide: 358 out of 52,519

Enzymatic DNA synthesis for digital information storage

synthetic biology more details view paper
  • Downloaded 3,832 times
  • Download rankings, all-time:
    • Site-wide: 558 out of 52,519
    • In synthetic biology: 11 out of 504
  • Year to date:
    • Site-wide: 356 out of 52,519
  • Since beginning of last month:
    • Site-wide: 944 out of 52,519

Highly multiplexed in situ protein imaging with signal amplification by Immuno-SABER

cell biology more details view paper
  • Downloaded 3,793 times
  • Download rankings, all-time:
    • Site-wide: 575 out of 52,519
    • In cell biology: 18 out of 2,472
  • Year to date:
    • Site-wide: 73 out of 52,519
  • Since beginning of last month:
    • Site-wide: 103 out of 52,519

Current CRISPR gene drive systems are likely to be highly invasive in wild populations

synthetic biology more details view paper
  • Downloaded 3,628 times
  • Download rankings, all-time:
    • Site-wide: 627 out of 52,519
    • In synthetic biology: 13 out of 504
  • Year to date:
    • Site-wide: 10,915 out of 52,519
  • Since beginning of last month:
    • Site-wide: 12,862 out of 52,519

Barcoded oligonucleotides ligated on RNA amplified for multiplex and parallel in-situ analyses

cell biology more details view paper
  • Downloaded 3,367 times
  • Download rankings, all-time:
    • Site-wide: 717 out of 52,519
    • In cell biology: 20 out of 2,472
  • Year to date:
    • Site-wide: 1,007 out of 52,519
  • Since beginning of last month:
    • Site-wide: 1,136 out of 52,519

Unified rational protein engineering with sequence-only deep representation learning

synthetic biology more details view paper
  • Downloaded 3,220 times
  • Download rankings, all-time:
    • Site-wide: 789 out of 52,519
    • In synthetic biology: 16 out of 504
  • Year to date:
    • Site-wide: 66 out of 52,519
  • Since beginning of last month:
    • Site-wide: 75 out of 52,519

Rapid Sequential In Situ Multiplexing With DNA-Exchange-Imaging

bioengineering more details view paper
  • Downloaded 2,937 times
  • Download rankings, all-time:
    • Site-wide: 927 out of 52,519
    • In bioengineering: 12 out of 976
  • Year to date:
    • Site-wide: 19,093 out of 52,519
  • Since beginning of last month:
    • Site-wide: 18,555 out of 52,519

A homing CRISPR mouse resource for barcoding and lineage tracing

synthetic biology more details view paper
  • Downloaded 2,911 times
  • Download rankings, all-time:
    • Site-wide: 945 out of 52,519
    • In synthetic biology: 18 out of 504
  • Year to date:
    • Site-wide: 6,290 out of 52,519
  • Since beginning of last month:
    • Site-wide: 18,356 out of 52,519

Precise Cas9 targeting enables genomic mutation prevention

synthetic biology more details view paper
  • Downloaded 2,394 times
  • Download rankings, all-time:
    • Site-wide: 1,347 out of 52,519
    • In synthetic biology: 25 out of 504
  • Year to date:
    • Site-wide: 27,115 out of 52,519
  • Since beginning of last month:
    • Site-wide: 41,168 out of 52,519

Assembly of Radically Recoded E. coli Genome Segments

synthetic biology more details view paper
  • Downloaded 2,287 times
  • Download rankings, all-time:
    • Site-wide: 1,469 out of 52,519
    • In synthetic biology: 27 out of 504
  • Year to date:
    • Site-wide: 13,517 out of 52,519
  • Since beginning of last month:
    • Site-wide: 12,608 out of 52,519

The experimental design and data interpretation in ‘Unexpected mutations after CRISPR Cas9 editing in vivo’ by Schaefer et al. are insufficient to support the conclusions drawn by the authors

genetics more details view paper
  • Downloaded 1,955 times
  • Download rankings, all-time:
    • Site-wide: 1,916 out of 52,519
    • In genetics: 190 out of 3,067
  • Year to date:
    • Site-wide: 25,122 out of 52,519
  • Since beginning of last month:
    • Site-wide: 36,091 out of 52,519

Recombineering in Vibrio natriegens

synthetic biology more details view paper
  • Downloaded 1,944 times
  • Download rankings, all-time:
    • Site-wide: 1,938 out of 52,519
    • In synthetic biology: 35 out of 504
  • Year to date:
    • Site-wide: 4,616 out of 52,519
  • Since beginning of last month:
    • Site-wide: 4,928 out of 52,519

Single-cell sequencing reveals αβ chain pairing shapes the T cell repertoire

immunology more details view paper
  • Downloaded 1,553 times
  • Download rankings, all-time:
    • Site-wide: 2,820 out of 52,519
    • In immunology: 31 out of 1,212
  • Year to date:
    • Site-wide: 10,083 out of 52,519
  • Since beginning of last month:
    • Site-wide: 13,048 out of 52,519

Efficient in situ barcode sequencing using padlock probe-based BaristaSeq

molecular biology more details view paper
  • Downloaded 1,493 times
  • Download rankings, all-time:
    • Site-wide: 3,014 out of 52,519
    • In molecular biology: 81 out of 1,586
  • Year to date:
    • Site-wide: 14,343 out of 52,519
  • Since beginning of last month:
    • Site-wide: 18,472 out of 52,519

Multiplexed imaging using same species primary antibodies with signal amplification

cell biology more details view paper
  • Downloaded 1,318 times
  • Download rankings, all-time:
    • Site-wide: 3,689 out of 52,519
    • In cell biology: 97 out of 2,472
  • Year to date:
    • Site-wide: 4,957 out of 52,519
  • Since beginning of last month:
    • Site-wide: 7,475 out of 52,519

Concerning RNA-Guided Gene Drives for the Alteration of Wild Populations

synthetic biology more details view paper
  • Downloaded 1,259 times
  • Download rankings, all-time:
    • Site-wide: 3,977 out of 52,519
    • In synthetic biology: 59 out of 504
  • Year to date:
    • Site-wide: 36,037 out of 52,519
  • Since beginning of last month:
    • Site-wide: 45,431 out of 52,519

A systematic comparison of error correction enzymes by next-generation sequencing

synthetic biology more details view paper
  • Downloaded 1,243 times
  • Download rankings, all-time:
    • Site-wide: 4,053 out of 52,519
    • In synthetic biology: 62 out of 504
  • Year to date:
    • Site-wide: 24,855 out of 52,519
  • Since beginning of last month:
    • Site-wide: 26,388 out of 52,519

Enhanced bacterial immunity and mammalian genome editing via RNA polymerase-mediated dislodging of Cas9 from double strand DNA breaks.

molecular biology more details view paper
  • Downloaded 1,180 times
  • Download rankings, all-time:
    • Site-wide: 4,396 out of 52,519
    • In molecular biology: 123 out of 1,586
  • Year to date:
    • Site-wide: 12,218 out of 52,519
  • Since beginning of last month:
    • Site-wide: 17,065 out of 52,519

Reprogramming protein kinase substrate specificity through synthetic mutations

biochemistry more details view paper
  • Downloaded 1,155 times
  • Download rankings, all-time:
    • Site-wide: 4,548 out of 52,519
    • In biochemistry: 79 out of 1,474
  • Year to date:
    • Site-wide: 24,370 out of 52,519
  • Since beginning of last month:
    • Site-wide: 26,448 out of 52,519

Optimizing complex phenotypes through model-guided multiplex genome engineering

synthetic biology more details view paper
  • Downloaded 1,029 times
  • Download rankings, all-time:
    • Site-wide: 5,471 out of 52,519
    • In synthetic biology: 83 out of 504
  • Year to date:
    • Site-wide: 38,865 out of 52,519
  • Since beginning of last month:
    • Site-wide: 30,101 out of 52,519

Circularization of genes and chromosome by CRISPR in human cells

genomics more details view paper
  • Downloaded 1,028 times
  • Download rankings, all-time:
    • Site-wide: 5,485 out of 52,519
    • In genomics: 936 out of 3,756
  • Year to date:
    • Site-wide: 16,249 out of 52,519
  • Since beginning of last month:
    • Site-wide: 17,884 out of 52,519

Engineering post-translational proofreading to discriminate non-standard amino acids

synthetic biology more details view paper
  • Downloaded 1,024 times
  • Download rankings, all-time:
    • Site-wide: 5,525 out of 52,519
    • In synthetic biology: 84 out of 504
  • Year to date:
    • Site-wide: 31,126 out of 52,519
  • Since beginning of last month:
    • Site-wide: 40,213 out of 52,519

Establishing a cell-free Vibrio natriegens expression system

synthetic biology more details view paper
  • Downloaded 949 times
  • Download rankings, all-time:
    • Site-wide: 6,257 out of 52,519
    • In synthetic biology: 96 out of 504
  • Year to date:
    • Site-wide: 10,381 out of 52,519
  • Since beginning of last month:
    • Site-wide: 21,514 out of 52,519

Biosensor libraries harness large classes of binding domains for allosteric transcription regulators

synthetic biology more details view paper
  • Downloaded 937 times
  • Download rankings, all-time:
    • Site-wide: 6,385 out of 52,519
    • In synthetic biology: 103 out of 504
  • Year to date:
    • Site-wide: 32,195 out of 52,519
  • Since beginning of last month:
    • Site-wide: 33,447 out of 52,519

The whale shark genome reveals how genomic and physiological properties scale with body size

genomics more details view paper
  • Downloaded 932 times
  • Download rankings, all-time:
    • Site-wide: 6,441 out of 52,519
    • In genomics: 1,065 out of 3,756
  • Year to date:
    • Site-wide: 3,646 out of 52,519
  • Since beginning of last month:
    • Site-wide: 5,706 out of 52,519

Dissecting limiting factors of the Protein synthesis Using Recombinant Elements (PURE) system

bioengineering more details view paper
  • Downloaded 839 times
  • Download rankings, all-time:
    • Site-wide: 7,552 out of 52,519
    • In bioengineering: 119 out of 976
  • Year to date:
    • Site-wide: 50,069 out of 52,519
  • Since beginning of last month:
    • Site-wide: 50,932 out of 52,519

Systemic post-translational control of bacterial metabolism regulates adaptation in dynamic environments

systems biology more details view paper
  • Downloaded 799 times
  • Download rankings, all-time:
    • Site-wide: 8,148 out of 52,519
    • In systems biology: 226 out of 1,534
  • Year to date:
    • Site-wide: 16,001 out of 52,519
  • Since beginning of last month:
    • Site-wide: 21,209 out of 52,519

Long-term adaptive evolution of genomically recoded Escherichia coli

evolutionary biology more details view paper
  • Downloaded 747 times
  • Download rankings, all-time:
    • Site-wide: 9,027 out of 52,519
    • In evolutionary biology: 636 out of 3,671
  • Year to date:
    • Site-wide: 45,116 out of 52,519
  • Since beginning of last month:
    • Site-wide: 47,681 out of 52,519

Ethnically relevant consensus Korean reference genome towards personal reference genomes

genomics more details view paper
  • Downloaded 666 times
  • Download rankings, all-time:
    • Site-wide: 10,598 out of 52,519
    • In genomics: 1,514 out of 3,756
  • Year to date:
    • Site-wide: 39,569 out of 52,519
  • Since beginning of last month:
    • Site-wide: 46,213 out of 52,519

Spatial Information in Large-Scale Neural Recordings

neuroscience more details view paper
  • Downloaded 630 times
  • Download rankings, all-time:
    • Site-wide: 11,438 out of 52,519
    • In neuroscience: 1,813 out of 9,207
  • Year to date:
    • Site-wide: 46,820 out of 52,519
  • Since beginning of last month:
    • Site-wide: 42,628 out of 52,519

Significant abundance of cis configurations of mutations in diploid human genomes

genomics more details view paper
  • Downloaded 580 times
  • Download rankings, all-time:
    • Site-wide: 12,722 out of 52,519
    • In genomics: 1,724 out of 3,756
  • Year to date:
    • Site-wide: 14,277 out of 52,519
  • Since beginning of last month:
    • Site-wide: 13,329 out of 52,519

Cushing's Syndrome mutant PKAL205R exhibits altered substrate specificity

biochemistry more details view paper
  • Downloaded 571 times
  • Download rankings, all-time:
    • Site-wide: 12,966 out of 52,519
    • In biochemistry: 251 out of 1,474
  • Year to date:
    • Site-wide: 36,632 out of 52,519
  • Since beginning of last month:
    • Site-wide: 40,995 out of 52,519

Toward D-Peptide Biosynthesis: Elongation Factor P Enables Ribosomal Incorporation Of Consecutive D-Amino Acids

biochemistry more details view paper
  • Downloaded 552 times
  • Download rankings, all-time:
    • Site-wide: 13,559 out of 52,519
    • In biochemistry: 261 out of 1,474
  • Year to date:
    • Site-wide: 33,041 out of 52,519
  • Since beginning of last month:
    • Site-wide: 31,055 out of 52,519

Millstone: Software for Multiplex Microbial Genome Analysis and Engineering

synthetic biology more details view paper
  • Downloaded 511 times
  • Download rankings, all-time:
    • Site-wide: 15,035 out of 52,519
    • In synthetic biology: 244 out of 504
  • Year to date:
    • Site-wide: 41,924 out of 52,519
  • Since beginning of last month:
    • Site-wide: 34,529 out of 52,519

Emergent rules for codon choice elucidated by editing rare arginine codons in Escherichia coli

genomics more details view paper
  • Downloaded 420 times
  • Download rankings, all-time:
    • Site-wide: 18,910 out of 52,519
    • In genomics: 2,215 out of 3,756
  • Year to date:
    • Site-wide: 44,951 out of 52,519
  • Since beginning of last month:
    • Site-wide: 41,919 out of 52,519

Simulating serial-target antibacterial drug synergies using flux balance analysis

systems biology more details view paper
  • Downloaded 397 times
  • Download rankings, all-time:
    • Site-wide: 20,040 out of 52,519
    • In systems biology: 621 out of 1,534
  • Year to date:
    • Site-wide: 50,248 out of 52,519
  • Since beginning of last month:
    • Site-wide: 50,516 out of 52,519

Physiological Assembly Of Functionally Active 30S Ribosomal Subunits From In Vitro Synthesized Parts

biochemistry more details view paper
  • Downloaded 303 times
  • Download rankings, all-time:
    • Site-wide: 26,024 out of 52,519
    • In biochemistry: 610 out of 1,474
  • Year to date:
    • Site-wide: 44,054 out of 52,519
  • Since beginning of last month:
    • Site-wide: 45,613 out of 52,519

Sign up for the Rxivist weekly newsletter! (Click here for more details.)


News