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Author: George Church

Rankings

  • All-time downloads: 197,770 (rank: 251 out of 511,089)
  • Categories:
    • biochemistry: 4,760 (rank: 357 out of 21,457)
    • bioengineering: 7,287 (rank: 74 out of 13,766)
    • bioinformatics: 8,591 (rank: 839 out of 36,888)
    • cell biology: 25,053 (rank: 1 out of 33,954)
    • evolutionary biology: 1,972 (rank: 2,294 (tie) out of 22,293)
    • genetics: 2,171 (rank: 7,691 (tie) out of 38,712)
    • genomics: 40,626 (rank: 173 out of 45,704)
    • microbiology: 1,364 (rank: 8,066 (tie) out of 52,260)
    • molecular biology: 21,718 (rank: 38 out of 24,245)
    • neuroscience: 8,435 (rank: 1,299 out of 73,714)
    • synthetic biology: 73,167 (rank: 1 out of 4,554)
    • systems biology: 2,626 (rank: 1,250 out of 12,894)

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Preprints

Vibrio natriegens, a new genomic powerhouse

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Reversal of ageing- and injury-induced vision loss by Tet-dependent epigenetic reprogramming

molecular biology more details view paper
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Unified rational protein engineering with sequence-only deep representation learning

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Inter-homologue repair in fertilized human eggs?

cell biology more details view paper
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Expansion Sequencing: Spatially Precise In Situ Transcriptomics in Intact Biological Systems

genomics more details view paper
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Conneconomics: The Economics of Dense, Large-Scale, High-Resolution Neural Connectomics

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Extensive sequencing of seven human genomes to characterize benchmark reference materials

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Rapidly evolving homing CRISPR barcodes

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Highly-efficient Cas9-mediated transcriptional programming

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Enabling large-scale genome editing by reducing DNA nicking

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Highly multiplexed in situ protein imaging with signal amplification by Immuno-SABER

cell biology more details view paper
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Daisy-chain gene drives for the alteration of local populations

synthetic biology more details view paper
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Barcoded oligonucleotides ligated on RNA amplified for multiplex and parallel in-situ analyses

cell biology more details view paper
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CasFinder: Flexible algorithm for identifying specific Cas9 targets in genomes

genomics more details view paper
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Enzymatic DNA synthesis for digital information storage

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The predictive power of the microbiome exceeds that of genome-wide association studies in the discrimination of complex human disease

bioinformatics more details view paper
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Current CRISPR gene drive systems are likely to be highly invasive in wild populations

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Accurate chromosome-scale haplotype-resolved assembly of human genomes

bioinformatics more details view paper
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A homing CRISPR mouse resource for barcoding and lineage tracing

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Extensive Mammalian Germline Genome Engineering

synthetic biology more details view paper
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Rapid Sequential In Situ Multiplexing With DNA-Exchange-Imaging

bioengineering more details view paper
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Evolutionary dynamics of CRISPR gene drives

synthetic biology more details view paper
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Assembly of Radically Recoded E. coli Genome Segments

synthetic biology more details view paper
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Recombineering in Vibrio natriegens

synthetic biology more details view paper
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Precise Cas9 targeting enables genomic mutation prevention

synthetic biology more details view paper
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Rapid and scalable in vitro production of single-stranded DNA

molecular biology more details view paper
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Multiplexed in situ protein imaging using DNA-barcoded antibodies with extended hybridization chain reactions

cell biology more details view paper
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The experimental design and data interpretation in ‘Unexpected mutations after CRISPR Cas9 editing in vivo’ by Schaefer et al. are insufficient to support the conclusions drawn by the authors

genetics more details view paper
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Efficient in situ barcode sequencing using padlock probe-based BaristaSeq

molecular biology more details view paper
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High-throughput creation and functional profiling of eukaryotic DNA sequence variant libraries using CRISPR/Cas9

bioengineering more details view paper
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The whale shark genome reveals how genomic and physiological properties scale with body size

genomics more details view paper
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Genetic design automation for autonomous formation of multicellular shapes from a single cell progenitor

synthetic biology more details view paper
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A systematic comparison of error correction enzymes by next-generation sequencing

synthetic biology more details view paper
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Photon-directed Multiplexed Enzymatic DNA Synthesis for Molecular Digital Data Storage

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An orthogonal differentiation platform for genomically programming stem cells, organoids, and bioprinted tissues

bioengineering more details view paper
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Reprogramming protein kinase substrate specificity through synthetic mutations

biochemistry more details view paper
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Concerning RNA-Guided Gene Drives for the Alteration of Wild Populations

synthetic biology more details view paper
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Improved bacterial recombineering by parallelized protein discovery

microbiology more details view paper
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Enhanced bacterial immunity and mammalian genome editing via RNA polymerase-mediated dislodging of Cas9 from double strand DNA breaks.

molecular biology more details view paper
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A DNA nanoscope that identifies and precisely localizes over a hundred unique molecular features with nanometer accuracy

biochemistry more details view paper
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CRISPR-mediated biocontainment

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Engineering post-translational proofreading to discriminate non-standard amino acids

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Optimizing complex phenotypes through model-guided multiplex genome engineering

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Systemic post-translational control of bacterial metabolism regulates adaptation in dynamic environments

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Induced Pluripotent Stem Cell-derived CAR-Macrophage Cells with Antigen-dependent Anti-Cancer Cell Functions for Liquid and Solid Tumors

cell biology more details view paper
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Multi-pronged human protein mimicry by SARS-CoV-2 reveals bifurcating potential for MHC detection and immune evasion

evolutionary biology more details view paper
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Biosensor libraries harness large classes of binding domains for allosteric transcription regulators

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Significant abundance of cis configurations of mutations in diploid human genomes

genomics more details view paper
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Dissecting limiting factors of the Protein synthesis Using Recombinant Elements (PURE) system

bioengineering more details view paper
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Massively parallel quantification of CRISPR editing in cells by TRAP-seq enables better design of Cas9, ABE, CBE gRNAs of high efficiency and accuracy

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Fluorescent in situ sequencing of DNA barcoded antibodies

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Citizen-Centered, Auditable, and Privacy-Preserving Population Genomics

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Characterizing the portability of RecT-mediated oligonucleotide recombination

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Long-term adaptive evolution of genomically recoded Escherichia coli

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Attribution of genetic engineering: a practical and accurate machine learning toolkit for biosecurity

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Ethnically relevant consensus Korean reference genome towards personal reference genomes

genomics more details view paper
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Toward D-Peptide Biosynthesis: Elongation Factor P Enables Ribosomal Incorporation Of Consecutive D-Amino Acids

biochemistry more details view paper
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Spatial Information in Large-Scale Neural Recordings

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Cushing's Syndrome mutant PKAL205R exhibits altered substrate specificity

biochemistry more details view paper
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Towards Practical and Robust DNA-based Data Archiving by Codec System Named ‘Yin-Yang’

synthetic biology more details view paper
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Robust differentiation of human pluripotent stem cells into endothelial cells via temporal modulation of ETV2 with modified mRNA

cell biology more details view paper
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Emergent rules for codon choice elucidated by editing rare arginine codons in Escherichia coli

genomics more details view paper
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Simulating serial-target antibacterial drug synergies using flux balance analysis

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Multiplex single-molecule kinetics of nanopore-coupled polymerases

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Physiological Assembly Of Functionally Active 30S Ribosomal Subunits From In Vitro Synthesized Parts

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TBDB: A database of structurally annotated T-box riboswitch-tRNA pairs

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L1CAM is not Associated with Extracellular Vesicles in Human Cerebrospinal Fluid or Plasma

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Comparison of Extracellular Vesicle Isolation Methods from Human Biofluids using Single Molecule Arrays

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