Rxivist combines preprints from bioRxiv with data from Twitter to help you find the papers being discussed in your field. Currently indexing 63,068 bioRxiv papers from 279,747 authors.

Downloads per author, site-wide

Preprints

Efficient chromosome-scale haplotype-resolved assembly of human genomes

No bioRxiv download data for this paper yet.

Genetic design automation for autonomous formation of multicellular shapes from a single cell progenitor

No bioRxiv download data for this paper yet.

Citizen-Centered, Auditable, and Privacy-Preserving Population Genomics

No bioRxiv download data for this paper yet.

Vibrio natriegens, a new genomic powerhouse

• Downloaded 15,138 times
• Download rankings, all-time:
  • Site-wide: 44 out of 63,068
  • In genomics: 12 out of 4,328
• Year to date:
  • Site-wide: 315 out of 63,068
• Since beginning of last month:
  • Site-wide: 301 out of 63,068

Inter-homologue repair in fertilized human eggs?

• Downloaded 9,888 times
• Download rankings, all-time:
  • Site-wide: 107 out of 63,068
  • In cell biology: 4 out of 3,008
• Year to date:
  • Site-wide: 13,012 out of 63,068
• Since beginning of last month:
  • Site-wide: 9,820 out of 63,068

Reversal of ageing- and injury-induced vision loss by Tet-dependent epigenetic reprogramming

• Downloaded 7,452 times
• Download rankings, all-time:
  • Site-wide: 186 out of 63,068
  • In molecular biology: 5 out of 1,980
• Year to date:
  • Site-wide: 34 out of 63,068
• Since beginning of last month:
  • Site-wide: 22 out of 63,068

Tumor-infiltrating immune repertoires captured by single-cell barcoding in emulsion

• Downloaded 6,087 times
• Download rankings, all-time:
  • Site-wide: 285 out of 63,068
  • In immunology: 4 out of 1,568
• Year to date:
  • Site-wide: 4,238 out of 63,068
• Since beginning of last month:
  • Site-wide: 13,229 out of 63,068

Conneconomics: The Economics of Dense, Large-Scale, High-Resolution Neural Connectomics

• Downloaded 6,032 times
• Download rankings, all-time:
  • Site-wide: 292 out of 63,068
  • In neuroscience: 42 out of 11,260
• Year to date:
  • Site-wide: 5,637 out of 63,068
• Since beginning of last month:
  • Site-wide: 8,844 out of 63,068

Rapidly evolving homing CRISPR barcodes

• Downloaded 5,809 times
• Download rankings, all-time:
  • Site-wide: 312 out of 63,068
  • In synthetic biology: 6 out of 599
• Year to date:
  • Site-wide: 17,554 out of 63,068
• Since beginning of last month:
  • Site-wide: 28,834 out of 63,068

Extensive sequencing of seven human genomes to characterize benchmark reference materials

• Downloaded 5,754 times
• Download rankings, all-time:
  • Site-wide: 317 out of 63,068
  • In genomics: 84 out of 4,328
• Year to date:
  • Site-wide: 16,938 out of 63,068
• Since beginning of last month:
  • Site-wide: 25,090 out of 63,068

Highly-efficient Cas9-mediated transcriptional programming

• Downloaded 5,538 times
• Download rankings, all-time:
  • Site-wide: 337 out of 63,068
  • In synthetic biology: 7 out of 599
• Year to date:
  • Site-wide: 15,569 out of 63,068
• Since beginning of last month:
  • Site-wide: 11,685 out of 63,068

Unified rational protein engineering with sequence-only deep representation learning

• Downloaded 5,044 times
• Download rankings, all-time:
  • Site-wide: 396 out of 63,068
  • In synthetic biology: 8 out of 599
• Year to date:
  • Site-wide: 71 out of 63,068
• Since beginning of last month:
  • Site-wide: 153 out of 63,068

Daisy-chain gene drives for the alteration of local populations

• Downloaded 4,991 times
• Download rankings, all-time:
  • Site-wide: 401 out of 63,068
  • In synthetic biology: 9 out of 599
• Year to date:
  • Site-wide: 2,358 out of 63,068
• Since beginning of last month:
  • Site-wide: 22,246 out of 63,068

Enabling large-scale genome editing by reducing DNA nicking

• Downloaded 4,941 times
• Download rankings, all-time:
  • Site-wide: 412 out of 63,068
  • In synthetic biology: 10 out of 599
• Year to date:
  • Site-wide: 74 out of 63,068
• Since beginning of last month:
  • Site-wide: 3,397 out of 63,068

Highly multiplexed in situ protein imaging with signal amplification by Immuno-SABER

• Downloaded 4,725 times
• Download rankings, all-time:
  • Site-wide: 449 out of 63,068
  • In cell biology: 9 out of 3,008
• Year to date:
  • Site-wide: 108 out of 63,068
• Since beginning of last month:
  • Site-wide: 668 out of 63,068

Toward machine-guided design of proteins

• Downloaded 4,652 times
• Download rankings, all-time:
  • Site-wide: 463 out of 63,068
  • In synthetic biology: 11 out of 599
• Year to date:
  • Site-wide: 369 out of 63,068
• Since beginning of last month:
  • Site-wide: 776 out of 63,068

CasFinder: Flexible algorithm for identifying specific Cas9 targets in genomes

• Downloaded 4,422 times
• Download rankings, all-time:
  • Site-wide: 513 out of 63,068
  • In genomics: 135 out of 4,328
• Year to date:
  • Site-wide: 7,321 out of 63,068
• Since beginning of last month:
  • Site-wide: 9,088 out of 63,068

Enzymatic DNA synthesis for digital information storage

• Downloaded 4,157 times
• Download rankings, all-time:
  • Site-wide: 583 out of 63,068
  • In synthetic biology: 13 out of 599
• Year to date:
  • Site-wide: 571 out of 63,068
• Since beginning of last month:
  • Site-wide: 4,326 out of 63,068

Barcoded oligonucleotides ligated on RNA amplified for multiplex and parallel in-situ analyses

• Downloaded 3,833 times
• Download rankings, all-time:
  • Site-wide: 684 out of 63,068
  • In cell biology: 21 out of 3,008
• Year to date:
  • Site-wide: 987 out of 63,068
• Since beginning of last month:
  • Site-wide: 1,654 out of 63,068

Current CRISPR gene drive systems are likely to be highly invasive in wild populations

• Downloaded 3,701 times
• Download rankings, all-time:
  • Site-wide: 729 out of 63,068
  • In synthetic biology: 15 out of 599
• Year to date:
  • Site-wide: 14,398 out of 63,068
• Since beginning of last month:
  • Site-wide: 25,138 out of 63,068

A homing CRISPR mouse resource for barcoding and lineage tracing

• Downloaded 3,002 times
• Download rankings, all-time:
  • Site-wide: 1,082 out of 63,068
  • In synthetic biology: 21 out of 599
• Year to date:
  • Site-wide: 8,665 out of 63,068
• Since beginning of last month:
  • Site-wide: 15,577 out of 63,068

Rapid Sequential In Situ Multiplexing With DNA-Exchange-Imaging

• Downloaded 2,996 times
• Download rankings, all-time:
  • Site-wide: 1,084 out of 63,068
  • In bioengineering: 14 out of 1,248
• Year to date:
  • Site-wide: 23,830 out of 63,068
• Since beginning of last month:
  • Site-wide: 35,781 out of 63,068

Evolutionary dynamics of CRISPR gene drives

• Downloaded 2,505 times
• Download rankings, all-time:
  • Site-wide: 1,491 out of 63,068
  • In synthetic biology: 26 out of 599
• Year to date:
  • Site-wide: 31,598 out of 63,068
• Since beginning of last month:
  • Site-wide: 35,446 out of 63,068

Precise Cas9 targeting enables genomic mutation prevention

• Downloaded 2,437 times
• Download rankings, all-time:
  • Site-wide: 1,577 out of 63,068
  • In synthetic biology: 27 out of 599
• Year to date:
  • Site-wide: 34,740 out of 63,068
• Since beginning of last month:
  • Site-wide: 44,726 out of 63,068

Assembly of Radically Recoded E. coli Genome Segments

• Downloaded 2,366 times
• Download rankings, all-time:
  • Site-wide: 1,659 out of 63,068
  • In synthetic biology: 30 out of 599
• Year to date:
  • Site-wide: 16,373 out of 63,068
• Since beginning of last month:
  • Site-wide: 22,260 out of 63,068

Recombineering in Vibrio natriegens

• Downloaded 2,097 times
• Download rankings, all-time:
  • Site-wide: 2,062 out of 63,068
  • In synthetic biology: 39 out of 599
• Year to date:
  • Site-wide: 5,361 out of 63,068
• Since beginning of last month:
  • Site-wide: 10,031 out of 63,068

The experimental design and data interpretation in ‘Unexpected mutations after CRISPR Cas9 editing in vivo’ by Schaefer et al. are insufficient to support the conclusions drawn by the authors

• Downloaded 1,996 times
• Download rankings, all-time:
  • Site-wide: 2,260 out of 63,068
  • In genetics: 216 out of 3,574
• Year to date:
  • Site-wide: 33,171 out of 63,068
• Since beginning of last month:
  • Site-wide: 35,171 out of 63,068

Single-cell sequencing reveals αβ chain pairing shapes the T cell repertoire

• Downloaded 1,730 times
• Download rankings, all-time:
  • Site-wide: 2,878 out of 63,068
  • In immunology: 33 out of 1,568
• Year to date:
  • Site-wide: 8,117 out of 63,068
• Since beginning of last month:
  • Site-wide: 8,664 out of 63,068

Efficient in situ barcode sequencing using padlock probe-based BaristaSeq

• Downloaded 1,576 times
• Download rankings, all-time:
  • Site-wide: 3,351 out of 63,068
  • In molecular biology: 98 out of 1,980
• Year to date:
  • Site-wide: 16,671 out of 63,068
• Since beginning of last month:
  • Site-wide: 17,385 out of 63,068

High-throughput creation and functional profiling of eukaryotic DNA sequence variant libraries using CRISPR/Cas9

• Downloaded 1,571 times
• Download rankings, all-time:
  • Site-wide: 3,368 out of 63,068
  • In bioengineering: 57 out of 1,248
• Year to date:
  • Site-wide: 23,335 out of 63,068
• Since beginning of last month:
  • Site-wide: 27,251 out of 63,068

Multiplexed imaging using same species primary antibodies with signal amplification

• Downloaded 1,486 times
• Download rankings, all-time:
  • Site-wide: 3,703 out of 63,068
  • In cell biology: 101 out of 3,008
• Year to date:
  • Site-wide: 5,370 out of 63,068
• Since beginning of last month:
  • Site-wide: 6,849 out of 63,068

A systematic comparison of error correction enzymes by next-generation sequencing

• Downloaded 1,332 times
• Download rankings, all-time:
  • Site-wide: 4,427 out of 63,068
  • In synthetic biology: 67 out of 599
• Year to date:
  • Site-wide: 23,382 out of 63,068
• Since beginning of last month:
  • Site-wide: 20,705 out of 63,068

Concerning RNA-Guided Gene Drives for the Alteration of Wild Populations

• Downloaded 1,301 times
• Download rankings, all-time:
  • Site-wide: 4,613 out of 63,068
  • In synthetic biology: 69 out of 599
• Year to date:
  • Site-wide: 42,898 out of 63,068
• Since beginning of last month:
  • Site-wide: 45,576 out of 63,068

Enhanced bacterial immunity and mammalian genome editing via RNA polymerase-mediated dislodging of Cas9 from double strand DNA breaks.

• Downloaded 1,232 times
• Download rankings, all-time:
  • Site-wide: 5,035 out of 63,068
  • In molecular biology: 153 out of 1,980
• Year to date:
  • Site-wide: 17,816 out of 63,068
• Since beginning of last month:
  • Site-wide: 31,400 out of 63,068

Reprogramming protein kinase substrate specificity through synthetic mutations

• Downloaded 1,227 times
• Download rankings, all-time:
  • Site-wide: 5,061 out of 63,068
  • In biochemistry: 96 out of 1,823
• Year to date:
  • Site-wide: 25,932 out of 63,068
• Since beginning of last month:
  • Site-wide: 21,610 out of 63,068

The whale shark genome reveals how genomic and physiological properties scale with body size

• Downloaded 1,150 times
• Download rankings, all-time:
  • Site-wide: 5,655 out of 63,068
  • In genomics: 955 out of 4,328
• Year to date:
  • Site-wide: 3,713 out of 63,068
• Since beginning of last month:
  • Site-wide: 3,948 out of 63,068

Engineering post-translational proofreading to discriminate non-standard amino acids

• Downloaded 1,092 times
• Download rankings, all-time:
  • Site-wide: 6,175 out of 63,068
  • In synthetic biology: 96 out of 599
• Year to date:
  • Site-wide: 31,745 out of 63,068
• Since beginning of last month:
  • Site-wide: 38,391 out of 63,068

Circularization of genes and chromosome by CRISPR in human cells

• Downloaded 1,078 times
• Download rankings, all-time:
  • Site-wide: 6,301 out of 63,068
  • In genomics: 1,044 out of 4,328
• Year to date:
  • Site-wide: 22,354 out of 63,068
• Since beginning of last month:
  • Site-wide: 38,716 out of 63,068

Optimizing complex phenotypes through model-guided multiplex genome engineering

• Downloaded 1,073 times
• Download rankings, all-time:
  • Site-wide: 6,359 out of 63,068
  • In synthetic biology: 99 out of 599
• Year to date:
  • Site-wide: 44,199 out of 63,068
• Since beginning of last month:
  • Site-wide: 44,572 out of 63,068

Establishing a cell-free Vibrio natriegens expression system

• Downloaded 1,073 times
• Download rankings, all-time:
  • Site-wide: 6,361 out of 63,068
  • In synthetic biology: 97 out of 599
• Year to date:
  • Site-wide: 10,667 out of 63,068
• Since beginning of last month:
  • Site-wide: 6,044 out of 63,068

Biosensor libraries harness large classes of binding domains for allosteric transcription regulators

• Downloaded 974 times
• Download rankings, all-time:
  • Site-wide: 7,401 out of 63,068
  • In synthetic biology: 118 out of 599
• Year to date:
  • Site-wide: 40,984 out of 63,068
• Since beginning of last month:
  • Site-wide: 46,263 out of 63,068

Systemic post-translational control of bacterial metabolism regulates adaptation in dynamic environments

• Downloaded 917 times
• Download rankings, all-time:
  • Site-wide: 8,166 out of 63,068
  • In systems biology: 230 out of 1,786
• Year to date:
  • Site-wide: 14,669 out of 63,068
• Since beginning of last month:
  • Site-wide: 18,001 out of 63,068

Dissecting limiting factors of the Protein synthesis Using Recombinant Elements (PURE) system

• Downloaded 862 times
• Download rankings, all-time:
  • Site-wide: 9,000 out of 63,068
  • In bioengineering: 155 out of 1,248
• Year to date:
  • Site-wide: 60,153 out of 63,068
• Since beginning of last month:
  • Site-wide: 58,965 out of 63,068

Long-term adaptive evolution of genomically recoded Escherichia coli

• Downloaded 784 times
• Download rankings, all-time:
  • Site-wide: 10,381 out of 63,068
  • In evolutionary biology: 700 out of 4,239
• Year to date:
  • Site-wide: 51,988 out of 63,068
• Since beginning of last month:
  • Site-wide: 45,343 out of 63,068

Ethnically relevant consensus Korean reference genome towards personal reference genomes

• Downloaded 695 times
• Download rankings, all-time:
  • Site-wide: 12,359 out of 63,068
  • In genomics: 1,709 out of 4,328
• Year to date:
  • Site-wide: 50,133 out of 63,068
• Since beginning of last month:
  • Site-wide: 52,913 out of 63,068

Significant abundance of cis configurations of mutations in diploid human genomes

• Downloaded 694 times
• Download rankings, all-time:
  • Site-wide: 12,371 out of 63,068
  • In genomics: 1,711 out of 4,328
• Year to date:
  • Site-wide: 13,940 out of 63,068
• Since beginning of last month:
  • Site-wide: 8,041 out of 63,068

Spatial Information in Large-Scale Neural Recordings

• Downloaded 653 times
• Download rankings, all-time:
  • Site-wide: 13,473 out of 63,068
  • In neuroscience: 2,177 out of 11,260
• Year to date:
  • Site-wide: 57,820 out of 63,068
• Since beginning of last month:
  • Site-wide: 56,290 out of 63,068

Cushing's Syndrome mutant PKAL205R exhibits altered substrate specificity

• Downloaded 609 times
• Download rankings, all-time:
  • Site-wide: 14,852 out of 63,068
  • In biochemistry: 304 out of 1,823
• Year to date:
  • Site-wide: 44,612 out of 63,068
• Since beginning of last month:
  • Site-wide: 35,220 out of 63,068

Toward D-Peptide Biosynthesis: Elongation Factor P Enables Ribosomal Incorporation Of Consecutive D-Amino Acids

• Downloaded 598 times
• Download rankings, all-time:
  • Site-wide: 15,242 out of 63,068
  • In biochemistry: 318 out of 1,823
• Year to date:
  • Site-wide: 39,001 out of 63,068
• Since beginning of last month:
  • Site-wide: 36,248 out of 63,068

Millstone: Software for Multiplex Microbial Genome Analysis and Engineering

• Downloaded 558 times
• Download rankings, all-time:
  • Site-wide: 16,700 out of 63,068
  • In synthetic biology: 275 out of 599
• Year to date:
  • Site-wide: 45,456 out of 63,068
• Since beginning of last month:
  • Site-wide: 44,987 out of 63,068

Emergent rules for codon choice elucidated by editing rare arginine codons in Escherichia coli

• Downloaded 449 times
• Download rankings, all-time:
  • Site-wide: 21,875 out of 63,068
  • In genomics: 2,450 out of 4,328
• Year to date:
  • Site-wide: 54,345 out of 63,068
• Since beginning of last month:
  • Site-wide: 55,807 out of 63,068

Simulating serial-target antibacterial drug synergies using flux balance analysis

• Downloaded 417 times
• Download rankings, all-time:
  • Site-wide: 23,792 out of 63,068
  • In systems biology: 728 out of 1,786
• Year to date:
  • Site-wide: 60,728 out of 63,068
• Since beginning of last month:
  • Site-wide: 61,290 out of 63,068

Physiological Assembly Of Functionally Active 30S Ribosomal Subunits From In Vitro Synthesized Parts

• Downloaded 336 times
• Download rankings, all-time:
  • Site-wide: 29,725 out of 63,068
  • In biochemistry: 745 out of 1,823
• Year to date:
  • Site-wide: 52,546 out of 63,068
• Since beginning of last month:
  • Site-wide: 44,432 out of 63,068