Author: George Church
- ORCiD: http://orcid.org/0000-0001-6232-9969
- Most recently observed institution: Department of Genetics, Harvard Medical School
Rankings
- All-time downloads: 207,583 (rank: 244 )
- Categories:
- biochemistry: 5,258 (rank: 343 )
- bioengineering: 7,654 (rank: 75 )
- bioinformatics: 9,295 (rank: 796 )
- cell biology: 25,994 (rank: 1 )
- evolutionary biology: 2,280 (rank: 1,939 (tie) )
- genetics: 2,219 (rank: 7,991 (tie) )
- genomics: 42,776 (rank: 179 )
- microbiology: 1,431 (rank: 8,861 (tie) )
- molecular biology: 23,426 (rank: 38 )
- neuroscience: 9,039 (rank: 1,329 (tie) )
- synthetic biology: 75,425 (rank: 1 )
- systems biology: 2,786 (rank: 1,259 (tie) )
Downloads per author, site-wide
Preprints
Vibrio natriegens, a new genomic powerhouse
genomics more details view paper- Downloaded 18,188 times
- Download rankings, all-time:
- Site-wide: 356
- In genomics: 17
- Year to date:
- Site-wide: 2,887
- Since beginning of last month:
- Site-wide: 2,207
Reversal of ageing- and injury-induced vision loss by Tet-dependent epigenetic reprogramming
molecular biology more details view paper- Downloaded 17,627 times
- Download rankings, all-time:
- Site-wide: 365
- In molecular biology: 4
- Year to date:
- Site-wide: 759
- Since beginning of last month:
- Site-wide: 694
Unified rational protein engineering with sequence-only deep representation learning
synthetic biology more details view paper- Downloaded 10,773 times
- Download rankings, all-time:
- Site-wide: 679
- In synthetic biology: 4
- Year to date:
- Site-wide: 4,548
- Since beginning of last month:
- Site-wide: None
Inter-homologue repair in fertilized human eggs?
cell biology more details view paper- Downloaded 10,311 times
- Download rankings, all-time:
- Site-wide: 723
- In cell biology: 6
- Year to date:
- Site-wide: 48,584
- Since beginning of last month:
- Site-wide: 30,159
Expansion Sequencing: Spatially Precise In Situ Transcriptomics in Intact Biological Systems
genomics more details view paper- Downloaded 8,070 times
- Download rankings, all-time:
- Site-wide: 984
- In genomics: 91
- Year to date:
- Site-wide: 501
- Since beginning of last month:
- Site-wide: 466
Conneconomics: The Economics of Dense, Large-Scale, High-Resolution Neural Connectomics
neuroscience more details view paper- Downloaded 6,532 times
- Download rankings, all-time:
- Site-wide: 1,279
- In neuroscience: 62
- Year to date:
- Site-wide: 19,502
- Since beginning of last month:
- Site-wide: 26,738
Extensive sequencing of seven human genomes to characterize benchmark reference materials
genomics more details view paper- Downloaded 6,316 times
- Download rankings, all-time:
- Site-wide: 1,339
- In genomics: 129
- Year to date:
- Site-wide: 33,118
- Since beginning of last month:
- Site-wide: 35,039
Highly-efficient Cas9-mediated transcriptional programming
synthetic biology more details view paper- Downloaded 6,216 times
- Download rankings, all-time:
- Site-wide: 1,367
- In synthetic biology: 11
- Year to date:
- Site-wide: 8,502
- Since beginning of last month:
- Site-wide: 5,999
Rapidly evolving homing CRISPR barcodes
synthetic biology more details view paper- Downloaded 6,117 times
- Download rankings, all-time:
- Site-wide: 1,394
- In synthetic biology: 12
- Year to date:
- Site-wide: 49,062
- Since beginning of last month:
- Site-wide: 39,718
Enabling large-scale genome editing by reducing DNA nicking
synthetic biology more details view paper- Downloaded 6,019 times
- Download rankings, all-time:
- Site-wide: 1,431
- In synthetic biology: 13
- Year to date:
- Site-wide: 36,018
- Since beginning of last month:
- Site-wide: None
Highly multiplexed in situ protein imaging with signal amplification by Immuno-SABER
cell biology more details view paper- Downloaded 5,635 times
- Download rankings, all-time:
- Site-wide: 1,593
- In cell biology: 20
- Year to date:
- Site-wide: 20,000
- Since beginning of last month:
- Site-wide: 19,363
Barcoded oligonucleotides ligated on RNA amplified for multiplex and parallel in-situ analyses
cell biology more details view paper- Downloaded 5,344 times
- Download rankings, all-time:
- Site-wide: 1,703
- In cell biology: 24
- Year to date:
- Site-wide: 6,377
- Since beginning of last month:
- Site-wide: 5,041
Daisy-chain gene drives for the alteration of local populations
synthetic biology more details view paper- Downloaded 5,319 times
- Download rankings, all-time:
- Site-wide: 1,712
- In synthetic biology: 14
- Year to date:
- Site-wide: 82,689
- Since beginning of last month:
- Site-wide: None
The predictive power of the microbiome exceeds that of genome-wide association studies in the discrimination of complex human disease
bioinformatics more details view paper- Downloaded 5,091 times
- Download rankings, all-time:
- Site-wide: 1,801
- In bioinformatics: 153
- Year to date:
- Site-wide: 6,620
- Since beginning of last month:
- Site-wide: 5,250
CasFinder: Flexible algorithm for identifying specific Cas9 targets in genomes
genomics more details view paper- Downloaded 5,083 times
- Download rankings, all-time:
- Site-wide: 1,804
- In genomics: 185
- Year to date:
- Site-wide: 23,581
- Since beginning of last month:
- Site-wide: None
Enzymatic DNA synthesis for digital information storage
synthetic biology more details view paper- Downloaded 5,035 times
- Download rankings, all-time:
- Site-wide: 1,834
- In synthetic biology: 16
- Year to date:
- Site-wide: 18,970
- Since beginning of last month:
- Site-wide: 14,903
Current CRISPR gene drive systems are likely to be highly invasive in wild populations
synthetic biology more details view paper- Downloaded 4,024 times
- Download rankings, all-time:
- Site-wide: 2,503
- In synthetic biology: 23
- Year to date:
- Site-wide: 94,674
- Since beginning of last month:
- Site-wide: None
Accurate chromosome-scale haplotype-resolved assembly of human genomes
bioinformatics more details view paper- Downloaded 3,780 times
- Download rankings, all-time:
- Site-wide: 2,759
- In bioinformatics: 267
- Year to date:
- Site-wide: 4,618
- Since beginning of last month:
- Site-wide: 6,550
Extensive Mammalian Germline Genome Engineering
synthetic biology more details view paper- Downloaded 3,411 times
- Download rankings, all-time:
- Site-wide: 3,217
- In synthetic biology: 30
- Year to date:
- Site-wide: 19,193
- Since beginning of last month:
- Site-wide: None
A homing CRISPR mouse resource for barcoding and lineage tracing
synthetic biology more details view paper- Downloaded 3,272 times
- Download rankings, all-time:
- Site-wide: 3,416
- In synthetic biology: 32
- Year to date:
- Site-wide: 103,828
- Since beginning of last month:
- Site-wide: None
Rapid Sequential In Situ Multiplexing With DNA-Exchange-Imaging
bioengineering more details view paper- Downloaded 3,187 times
- Download rankings, all-time:
- Site-wide: 3,548
- In bioengineering: 35
- Year to date:
- Site-wide: 84,161
- Since beginning of last month:
- Site-wide: None
Evolutionary dynamics of CRISPR gene drives
synthetic biology more details view paper- Downloaded 2,715 times
- Download rankings, all-time:
- Site-wide: 4,427
- In synthetic biology: 42
- Year to date:
- Site-wide: 71,955
- Since beginning of last month:
- Site-wide: None
Recombineering in Vibrio natriegens
synthetic biology more details view paper- Downloaded 2,695 times
- Download rankings, all-time:
- Site-wide: 4,482
- In synthetic biology: 43
- Year to date:
- Site-wide: 18,975
- Since beginning of last month:
- Site-wide: 25,705
Assembly of Radically Recoded E. coli Genome Segments
synthetic biology more details view paper- Downloaded 2,652 times
- Download rankings, all-time:
- Site-wide: 4,606
- In synthetic biology: 46
- Year to date:
- Site-wide: 76,766
- Since beginning of last month:
- Site-wide: None
Multiplexed in situ protein imaging using DNA-barcoded antibodies with extended hybridization chain reactions
cell biology more details view paper- Downloaded 2,621 times
- Download rankings, all-time:
- Site-wide: 4,696
- In cell biology: 90
- Year to date:
- Site-wide: 5,838
- Since beginning of last month:
- Site-wide: 4,205
Precise Cas9 targeting enables genomic mutation prevention
synthetic biology more details view paper- Downloaded 2,588 times
- Download rankings, all-time:
- Site-wide: 4,763
- In synthetic biology: 50
- Year to date:
- Site-wide: 67,509
- Since beginning of last month:
- Site-wide: 62,528
Rapid and scalable in vitro production of single-stranded DNA
molecular biology more details view paper- Downloaded 2,488 times
- Download rankings, all-time:
- Site-wide: 5,061
- In molecular biology: 111
- Year to date:
- Site-wide: 36,047
- Since beginning of last month:
- Site-wide: 29,704
The experimental design and data interpretation in ‘Unexpected mutations after CRISPR Cas9 editing in vivo’ by Schaefer et al. are insufficient to support the conclusions drawn by the authors
genetics more details view paper- Downloaded 2,219 times
- Download rankings, all-time:
- Site-wide: 5,980
- In genetics: 288
- Year to date:
- Site-wide: 43,692
- Since beginning of last month:
- Site-wide: 47,583
Efficient in situ barcode sequencing using padlock probe-based BaristaSeq
molecular biology more details view paper- Downloaded 1,950 times
- Download rankings, all-time:
- Site-wide: 7,211
- In molecular biology: 176
- Year to date:
- Site-wide: 41,938
- Since beginning of last month:
- Site-wide: None
Genetic design automation for autonomous formation of multicellular shapes from a single cell progenitor
synthetic biology more details view paper- Downloaded 1,771 times
- Download rankings, all-time:
- Site-wide: 8,338
- In synthetic biology: 88
- Year to date:
- Site-wide: 17,860
- Since beginning of last month:
- Site-wide: None
High-throughput creation and functional profiling of eukaryotic DNA sequence variant libraries using CRISPR/Cas9
bioengineering more details view paper- Downloaded 1,770 times
- Download rankings, all-time:
- Site-wide: 8,346
- In bioengineering: 136
- Year to date:
- Site-wide: 71,580
- Since beginning of last month:
- Site-wide: 59,370
An orthogonal differentiation platform for genomically programming stem cells, organoids, and bioprinted tissues
bioengineering more details view paper- Downloaded 1,741 times
- Download rankings, all-time:
- Site-wide: 8,567
- In bioengineering: 140
- Year to date:
- Site-wide: 10,244
- Since beginning of last month:
- Site-wide: None
The whale shark genome reveals how genomic and physiological properties scale with body size
genomics more details view paper- Downloaded 1,708 times
- Download rankings, all-time:
- Site-wide: 8,834
- In genomics: 994
- Year to date:
- Site-wide: 77,190
- Since beginning of last month:
- Site-wide: 73,877
A systematic comparison of error correction enzymes by next-generation sequencing
synthetic biology more details view paper- Downloaded 1,646 times
- Download rankings, all-time:
- Site-wide: 9,341
- In synthetic biology: 97
- Year to date:
- Site-wide: 36,395
- Since beginning of last month:
- Site-wide: 27,107
Photon-directed Multiplexed Enzymatic DNA Synthesis for Molecular Digital Data Storage
synthetic biology more details view paper- Downloaded 1,576 times
- Download rankings, all-time:
- Site-wide: 9,965
- In synthetic biology: 106
- Year to date:
- Site-wide: 26,540
- Since beginning of last month:
- Site-wide: None
A DNA nanoscope that identifies and precisely localizes over a hundred unique molecular features with nanometer accuracy
biochemistry more details view paper- Downloaded 1,563 times
- Download rankings, all-time:
- Site-wide: 10,072
- In biochemistry: 195
- Year to date:
- Site-wide: 5,820
- Since beginning of last month:
- Site-wide: 4,201
Improved bacterial recombineering by parallelized protein discovery
microbiology more details view paper- Downloaded 1,431 times
- Download rankings, all-time:
- Site-wide: 11,468
- In microbiology: 640
- Year to date:
- Site-wide: 35,577
- Since beginning of last month:
- Site-wide: 40,788
Reprogramming protein kinase substrate specificity through synthetic mutations
biochemistry more details view paper- Downloaded 1,427 times
- Download rankings, all-time:
- Site-wide: 11,511
- In biochemistry: 219
- Year to date:
- Site-wide: 69,961
- Since beginning of last month:
- Site-wide: None
Induced Pluripotent Stem Cell-derived CAR-Macrophage Cells with Antigen-dependent Anti-Cancer Cell Functions for Liquid and Solid Tumors
cell biology more details view paper- Downloaded 1,413 times
- Download rankings, all-time:
- Site-wide: 11,664
- In cell biology: 327
- Year to date:
- Site-wide: 5,101
- Since beginning of last month:
- Site-wide: 5,339
Concerning RNA-Guided Gene Drives for the Alteration of Wild Populations
synthetic biology more details view paper- Downloaded 1,411 times
- Download rankings, all-time:
- Site-wide: 11,708
- In synthetic biology: 130
- Year to date:
- Site-wide: 84,624
- Since beginning of last month:
- Site-wide: 93,251
Multi-pronged human protein mimicry by SARS-CoV-2 reveals bifurcating potential for MHC detection and immune evasion
evolutionary biology more details view paper- Downloaded 1,405 times
- Download rankings, all-time:
- Site-wide: 11,783
- In evolutionary biology: 419
- Year to date:
- Site-wide: 4,822
- Since beginning of last month:
- Site-wide: None
CRISPR-mediated biocontainment
synthetic biology more details view paper- Downloaded 1,381 times
- Download rankings, all-time:
- Site-wide: 12,117
- In synthetic biology: 139
- Year to date:
- Site-wide: 33,564
- Since beginning of last month:
- Site-wide: 23,916
Enhanced bacterial immunity and mammalian genome editing via RNA polymerase-mediated dislodging of Cas9 from double strand DNA breaks.
molecular biology more details view paper- Downloaded 1,361 times
- Download rankings, all-time:
- Site-wide: 12,363
- In molecular biology: 340
- Year to date:
- Site-wide: 88,545
- Since beginning of last month:
- Site-wide: None
Engineering post-translational proofreading to discriminate non-standard amino acids
synthetic biology more details view paper- Downloaded 1,282 times
- Download rankings, all-time:
- Site-wide: 13,533
- In synthetic biology: 160
- Year to date:
- Site-wide: 67,521
- Since beginning of last month:
- Site-wide: 47,097
Systemic post-translational control of bacterial metabolism regulates adaptation in dynamic environments
systems biology more details view paper- Downloaded 1,242 times
- Download rankings, all-time:
- Site-wide: 14,175
- In systems biology: 286
- Year to date:
- Site-wide: 30,581
- Since beginning of last month:
- Site-wide: 17,255
Optimizing complex phenotypes through model-guided multiplex genome engineering
synthetic biology more details view paper- Downloaded 1,201 times
- Download rankings, all-time:
- Site-wide: 14,931
- In synthetic biology: 185
- Year to date:
- Site-wide: 83,361
- Since beginning of last month:
- Site-wide: None
Fluorescent in situ sequencing of DNA barcoded antibodies
neuroscience more details view paper- Downloaded 1,096 times
- Download rankings, all-time:
- Site-wide: 17,165
- In neuroscience: 2,156
- Year to date:
- Site-wide: 8,625
- Since beginning of last month:
- Site-wide: 5,530
Biosensor libraries harness large classes of binding domains for allosteric transcription regulators
synthetic biology more details view paper- Downloaded 1,094 times
- Download rankings, all-time:
- Site-wide: 17,210
- In synthetic biology: 214
- Year to date:
- Site-wide: 101,951
- Since beginning of last month:
- Site-wide: 73,212
Massively parallel quantification of CRISPR editing in cells by TRAP-seq enables better design of Cas9, ABE, CBE gRNAs of high efficiency and accuracy
systems biology more details view paper- Downloaded 1,030 times
- Download rankings, all-time:
- Site-wide: 18,836
- In systems biology: 391
- Year to date:
- Site-wide: 23,765
- Since beginning of last month:
- Site-wide: 33,266
Characterizing the portability of RecT-mediated oligonucleotide recombination
synthetic biology more details view paper- Downloaded 1,017 times
- Download rankings, all-time:
- Site-wide: 19,169
- In synthetic biology: 242
- Year to date:
- Site-wide: 16,647
- Since beginning of last month:
- Site-wide: 15,320
Significant abundance of cis configurations of mutations in diploid human genomes
genomics more details view paper- Downloaded 1,013 times
- Download rankings, all-time:
- Site-wide: 19,310
- In genomics: 1,979
- Year to date:
- Site-wide: 35,880
- Since beginning of last month:
- Site-wide: 33,740
Citizen-Centered, Auditable, and Privacy-Preserving Population Genomics
genomics more details view paper- Downloaded 976 times
- Download rankings, all-time:
- Site-wide: 20,315
- In genomics: 2,052
- Year to date:
- Site-wide: 18,736
- Since beginning of last month:
- Site-wide: 19,122
Dissecting limiting factors of the Protein synthesis Using Recombinant Elements (PURE) system
bioengineering more details view paper- Downloaded 956 times
- Download rankings, all-time:
- Site-wide: 20,941
- In bioengineering: 352
- Year to date:
- Site-wide: 118,193
- Since beginning of last month:
- Site-wide: None
Attribution of genetic engineering: a practical and accurate machine learning toolkit for biosecurity
synthetic biology more details view paper- Downloaded 947 times
- Download rankings, all-time:
- Site-wide: 21,236
- In synthetic biology: 270
- Year to date:
- Site-wide: 31,246
- Since beginning of last month:
- Site-wide: 27,317
Long-term adaptive evolution of genomically recoded Escherichia coli
evolutionary biology more details view paper- Downloaded 875 times
- Download rankings, all-time:
- Site-wide: 23,801
- In evolutionary biology: 1,114
- Year to date:
- Site-wide: 96,694
- Since beginning of last month:
- Site-wide: 72,791
Ethnically relevant consensus Korean reference genome towards personal reference genomes
genomics more details view paper- Downloaded 854 times
- Download rankings, all-time:
- Site-wide: 24,634
- In genomics: 2,375
- Year to date:
- Site-wide: 77,909
- Since beginning of last month:
- Site-wide: 75,332
Toward D-Peptide Biosynthesis: Elongation Factor P Enables Ribosomal Incorporation Of Consecutive D-Amino Acids
biochemistry more details view paper- Downloaded 791 times
- Download rankings, all-time:
- Site-wide: 27,369
- In biochemistry: 649
- Year to date:
- Site-wide: 66,563
- Since beginning of last month:
- Site-wide: 57,716
Towards Practical and Robust DNA-based Data Archiving by Codec System Named ‘Yin-Yang’
synthetic biology more details view paper- Downloaded 764 times
- Download rankings, all-time:
- Site-wide: 28,718
- In synthetic biology: 369
- Year to date:
- Site-wide: 30,309
- Since beginning of last month:
- Site-wide: 20,829
Spatial Information in Large-Scale Neural Recordings
neuroscience more details view paper- Downloaded 759 times
- Download rankings, all-time:
- Site-wide: 29,013
- In neuroscience: 3,969
- Year to date:
- Site-wide: 102,689
- Since beginning of last month:
- Site-wide: 77,926
Cushing's Syndrome mutant PKAL205R exhibits altered substrate specificity
biochemistry more details view paper- Downloaded 729 times
- Download rankings, all-time:
- Site-wide: 30,711
- In biochemistry: 737
- Year to date:
- Site-wide: 104,438
- Since beginning of last month:
- Site-wide: 57,593
Robust differentiation of human pluripotent stem cells into endothelial cells via temporal modulation of ETV2 with modified mRNA
cell biology more details view paper- Downloaded 670 times
- Download rankings, all-time:
- Site-wide: 34,453
- In cell biology: 1,383
- Year to date:
- Site-wide: 44,424
- Since beginning of last month:
- Site-wide: 36,670
L1CAM is not Associated with Extracellular Vesicles in Human Cerebrospinal Fluid or Plasma
neuroscience more details view paper- Downloaded 652 times
- Download rankings, all-time:
- Site-wide: 35,744
- In neuroscience: 5,035
- Year to date:
- Site-wide: 7,568
- Since beginning of last month:
- Site-wide: 10,011
Emergent rules for codon choice elucidated by editing rare arginine codons in Escherichia coli
genomics more details view paper- Downloaded 568 times
- Download rankings, all-time:
- Site-wide: 42,549
- In genomics: 3,495
- Year to date:
- Site-wide: 115,928
- Since beginning of last month:
- Site-wide: None
Simulating serial-target antibacterial drug synergies using flux balance analysis
systems biology more details view paper- Downloaded 514 times
- Download rankings, all-time:
- Site-wide: 48,028
- In systems biology: 1,126
- Year to date:
- Site-wide: 84,343
- Since beginning of last month:
- Site-wide: 59,141
Multiplex single-molecule kinetics of nanopore-coupled polymerases
synthetic biology more details view paper- Downloaded 499 times
- Download rankings, all-time:
- Site-wide: 49,689
- In synthetic biology: 601
- Year to date:
- Site-wide: 34,173
- Since beginning of last month:
- Site-wide: 43,589
Physiological Assembly Of Functionally Active 30S Ribosomal Subunits From In Vitro Synthesized Parts
biochemistry more details view paper- Downloaded 447 times
- Download rankings, all-time:
- Site-wide: 56,167
- In biochemistry: 1,481
- Year to date:
- Site-wide: 108,244
- Since beginning of last month:
- Site-wide: None
TBDB: A database of structurally annotated T-box riboswitch-tRNA pairs
bioinformatics more details view paper- Downloaded 424 times
- Download rankings, all-time:
- Site-wide: 59,281
- In bioinformatics: 5,916
- Year to date:
- Site-wide: 38,998
- Since beginning of last month:
- Site-wide: 28,984
Comparison of Extracellular Vesicle Isolation Methods from Human Biofluids using Single Molecule Arrays
biochemistry more details view paper- Downloaded 301 times
- Download rankings, all-time:
- Site-wide: 80,119
- In biochemistry: 2,302
- Year to date:
- Site-wide: 12,119
- Since beginning of last month:
- Site-wide: 12,483
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News
- 27 Nov 2020: The website and API now include results pulled from medRxiv as well as bioRxiv.
- 18 Dec 2019: We're pleased to announce PanLingua, a new tool that enables you to search for machine-translated bioRxiv preprints using more than 100 different languages.
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