Rxivist combines preprints from bioRxiv with data from Twitter to help you find the papers being discussed in your field. Currently indexing 57,506 bioRxiv papers from 264,779 authors.

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Preprints

Vibrio natriegens, a new genomic powerhouse

• Downloaded 14,597 times
• Download rankings, all-time:
  • Site-wide: 43 out of 57,506
  • In genomics: 13 out of 4,027
• Year to date:
  • Site-wide: 368 out of 57,506
• Since beginning of last month:
  • Site-wide: 967 out of 57,506

Inter-homologue repair in fertilized human eggs?

• Downloaded 9,835 times
• Download rankings, all-time:
  • Site-wide: 101 out of 57,506
  • In cell biology: 4 out of 2,723
• Year to date:
  • Site-wide: 12,946 out of 57,506
• Since beginning of last month:
  • Site-wide: 13,649 out of 57,506

RNA-guided gene drives can efficiently and reversibly bias inheritance in wild yeast

• Downloaded 6,911 times
• Download rankings, all-time:
  • Site-wide: 195 out of 57,506
  • In synthetic biology: 4 out of 550
• Year to date:
  • Site-wide: 13,416 out of 57,506
• Since beginning of last month:
  • Site-wide: 17,228 out of 57,506

Tumor-infiltrating immune repertoires captured by single-cell barcoding in emulsion

• Downloaded 6,027 times
• Download rankings, all-time:
  • Site-wide: 259 out of 57,506
  • In immunology: 4 out of 1,372
• Year to date:
  • Site-wide: 3,728 out of 57,506
• Since beginning of last month:
  • Site-wide: 9,387 out of 57,506

Conneconomics: The Economics of Dense, Large-Scale, High-Resolution Neural Connectomics

• Downloaded 5,957 times
• Download rankings, all-time:
  • Site-wide: 267 out of 57,506
  • In neuroscience: 40 out of 10,103
• Year to date:
  • Site-wide: 5,400 out of 57,506
• Since beginning of last month:
  • Site-wide: 11,170 out of 57,506

Rapidly evolving homing CRISPR barcodes

• Downloaded 5,779 times
• Download rankings, all-time:
  • Site-wide: 286 out of 57,506
  • In synthetic biology: 6 out of 550
• Year to date:
  • Site-wide: 15,709 out of 57,506
• Since beginning of last month:
  • Site-wide: 19,531 out of 57,506

Extensive sequencing of seven human genomes to characterize benchmark reference materials

• Downloaded 5,718 times
• Download rankings, all-time:
  • Site-wide: 292 out of 57,506
  • In genomics: 80 out of 4,027
• Year to date:
  • Site-wide: 15,765 out of 57,506
• Since beginning of last month:
  • Site-wide: 10,386 out of 57,506

Highly-efficient Cas9-mediated transcriptional programming

• Downloaded 5,477 times
• Download rankings, all-time:
  • Site-wide: 315 out of 57,506
  • In synthetic biology: 7 out of 550
• Year to date:
  • Site-wide: 16,985 out of 57,506
• Since beginning of last month:
  • Site-wide: 17,882 out of 57,506

Reversal of ageing- and injury-induced vision loss by Tet-dependent epigenetic reprogramming

• Downloaded 4,967 times
• Download rankings, all-time:
  • Site-wide: 369 out of 57,506
  • In molecular biology: 8 out of 1,746
• Year to date:
  • Site-wide: 52 out of 57,506
• Since beginning of last month:
  • Site-wide: 4 out of 57,506

Daisy-chain gene drives for the alteration of local populations

• Downloaded 4,933 times
• Download rankings, all-time:
  • Site-wide: 374 out of 57,506
  • In synthetic biology: 8 out of 550
• Year to date:
  • Site-wide: 1,954 out of 57,506
• Since beginning of last month:
  • Site-wide: 15,125 out of 57,506

Enabling large-scale genome editing by reducing DNA nicking

• Downloaded 4,759 times
• Download rankings, all-time:
  • Site-wide: 400 out of 57,506
  • In synthetic biology: 9 out of 550
• Year to date:
  • Site-wide: 54 out of 57,506
• Since beginning of last month:
  • Site-wide: 1,912 out of 57,506

CasFinder: Flexible algorithm for identifying specific Cas9 targets in genomes

• Downloaded 4,347 times
• Download rankings, all-time:
  • Site-wide: 480 out of 57,506
  • In genomics: 129 out of 4,027
• Year to date:
  • Site-wide: 7,431 out of 57,506
• Since beginning of last month:
  • Site-wide: 6,726 out of 57,506

Toward machine-guided design of proteins

• Downloaded 4,245 times
• Download rankings, all-time:
  • Site-wide: 502 out of 57,506
  • In synthetic biology: 10 out of 550
• Year to date:
  • Site-wide: 384 out of 57,506
• Since beginning of last month:
  • Site-wide: 986 out of 57,506

Highly multiplexed in situ protein imaging with signal amplification by Immuno-SABER

• Downloaded 4,209 times
• Download rankings, all-time:
  • Site-wide: 513 out of 57,506
  • In cell biology: 15 out of 2,723
• Year to date:
  • Site-wide: 93 out of 57,506
• Since beginning of last month:
  • Site-wide: 850 out of 57,506

Enzymatic DNA synthesis for digital information storage

• Downloaded 4,003 times
• Download rankings, all-time:
  • Site-wide: 568 out of 57,506
  • In synthetic biology: 11 out of 550
• Year to date:
  • Site-wide: 464 out of 57,506
• Since beginning of last month:
  • Site-wide: 2,392 out of 57,506

Unified rational protein engineering with sequence-only deep representation learning

• Downloaded 3,936 times
• Download rankings, all-time:
  • Site-wide: 586 out of 57,506
  • In synthetic biology: 12 out of 550
• Year to date:
  • Site-wide: 70 out of 57,506
• Since beginning of last month:
  • Site-wide: 231 out of 57,506

Current CRISPR gene drive systems are likely to be highly invasive in wild populations

• Downloaded 3,662 times
• Download rankings, all-time:
  • Site-wide: 678 out of 57,506
  • In synthetic biology: 14 out of 550
• Year to date:
  • Site-wide: 13,352 out of 57,506
• Since beginning of last month:
  • Site-wide: 30,230 out of 57,506

Barcoded oligonucleotides ligated on RNA amplified for multiplex and parallel in-situ analyses

• Downloaded 3,577 times
• Download rankings, all-time:
  • Site-wide: 714 out of 57,506
  • In cell biology: 21 out of 2,723
• Year to date:
  • Site-wide: 1,060 out of 57,506
• Since beginning of last month:
  • Site-wide: 2,389 out of 57,506

Rapid Sequential In Situ Multiplexing With DNA-Exchange-Imaging

• Downloaded 2,969 times
• Download rankings, all-time:
  • Site-wide: 1,001 out of 57,506
  • In bioengineering: 13 out of 1,103
• Year to date:
  • Site-wide: 21,854 out of 57,506
• Since beginning of last month:
  • Site-wide: 25,166 out of 57,506

A homing CRISPR mouse resource for barcoding and lineage tracing

• Downloaded 2,953 times
• Download rankings, all-time:
  • Site-wide: 1,011 out of 57,506
  • In synthetic biology: 20 out of 550
• Year to date:
  • Site-wide: 7,913 out of 57,506
• Since beginning of last month:
  • Site-wide: 23,634 out of 57,506

Precise Cas9 targeting enables genomic mutation prevention

• Downloaded 2,418 times
• Download rankings, all-time:
  • Site-wide: 1,468 out of 57,506
  • In synthetic biology: 27 out of 550
• Year to date:
  • Site-wide: 31,359 out of 57,506
• Since beginning of last month:
  • Site-wide: 45,522 out of 57,506

Assembly of Radically Recoded E. coli Genome Segments

• Downloaded 2,330 times
• Download rankings, all-time:
  • Site-wide: 1,570 out of 57,506
  • In synthetic biology: 29 out of 550
• Year to date:
  • Site-wide: 15,176 out of 57,506
• Since beginning of last month:
  • Site-wide: 22,040 out of 57,506

Recombineering in Vibrio natriegens

• Downloaded 2,020 times
• Download rankings, all-time:
  • Site-wide: 1,993 out of 57,506
  • In synthetic biology: 37 out of 550
• Year to date:
  • Site-wide: 5,201 out of 57,506
• Since beginning of last month:
  • Site-wide: 9,970 out of 57,506

The experimental design and data interpretation in ‘Unexpected mutations after CRISPR Cas9 editing in vivo’ by Schaefer et al. are insufficient to support the conclusions drawn by the authors

• Downloaded 1,976 times
• Download rankings, all-time:
  • Site-wide: 2,076 out of 57,506
  • In genetics: 207 out of 3,295
• Year to date:
  • Site-wide: 30,285 out of 57,506
• Since beginning of last month:
  • Site-wide: 34,017 out of 57,506

Single-cell sequencing reveals αβ chain pairing shapes the T cell repertoire

• Downloaded 1,637 times
• Download rankings, all-time:
  • Site-wide: 2,887 out of 57,506
  • In immunology: 30 out of 1,372
• Year to date:
  • Site-wide: 9,278 out of 57,506
• Since beginning of last month:
  • Site-wide: 8,590 out of 57,506

Efficient in situ barcode sequencing using padlock probe-based BaristaSeq

• Downloaded 1,526 times
• Download rankings, all-time:
  • Site-wide: 3,225 out of 57,506
  • In molecular biology: 90 out of 1,746
• Year to date:
  • Site-wide: 17,014 out of 57,506
• Since beginning of last month:
  • Site-wide: 20,452 out of 57,506

Multiplexed imaging using same species primary antibodies with signal amplification

• Downloaded 1,402 times
• Download rankings, all-time:
  • Site-wide: 3,717 out of 57,506
  • In cell biology: 102 out of 2,723
• Year to date:
  • Site-wide: 5,315 out of 57,506
• Since beginning of last month:
  • Site-wide: 8,422 out of 57,506

A systematic comparison of error correction enzymes by next-generation sequencing

• Downloaded 1,288 times
• Download rankings, all-time:
  • Site-wide: 4,286 out of 57,506
  • In synthetic biology: 66 out of 550
• Year to date:
  • Site-wide: 24,530 out of 57,506
• Since beginning of last month:
  • Site-wide: 18,620 out of 57,506

Concerning RNA-Guided Gene Drives for the Alteration of Wild Populations

• Downloaded 1,288 times
• Download rankings, all-time:
  • Site-wide: 4,285 out of 57,506
  • In synthetic biology: 65 out of 550
• Year to date:
  • Site-wide: 38,281 out of 57,506
• Since beginning of last month:
  • Site-wide: 45,046 out of 57,506

Enhanced bacterial immunity and mammalian genome editing via RNA polymerase-mediated dislodging of Cas9 from double strand DNA breaks.

• Downloaded 1,211 times
• Download rankings, all-time:
  • Site-wide: 4,706 out of 57,506
  • In molecular biology: 135 out of 1,746
• Year to date:
  • Site-wide: 15,045 out of 57,506
• Since beginning of last month:
  • Site-wide: 29,196 out of 57,506

Reprogramming protein kinase substrate specificity through synthetic mutations

• Downloaded 1,182 times
• Download rankings, all-time:
  • Site-wide: 4,888 out of 57,506
  • In biochemistry: 87 out of 1,642
• Year to date:
  • Site-wide: 28,123 out of 57,506
• Since beginning of last month:
  • Site-wide: 28,615 out of 57,506

Engineering post-translational proofreading to discriminate non-standard amino acids

• Downloaded 1,072 times
• Download rankings, all-time:
  • Site-wide: 5,770 out of 57,506
  • In synthetic biology: 92 out of 550
• Year to date:
  • Site-wide: 28,743 out of 57,506
• Since beginning of last month:
  • Site-wide: 11,667 out of 57,506

Optimizing complex phenotypes through model-guided multiplex genome engineering

• Downloaded 1,061 times
• Download rankings, all-time:
  • Site-wide: 5,878 out of 57,506
  • In synthetic biology: 93 out of 550
• Year to date:
  • Site-wide: 39,118 out of 57,506
• Since beginning of last month:
  • Site-wide: 36,821 out of 57,506

Circularization of genes and chromosome by CRISPR in human cells

• Downloaded 1,061 times
• Download rankings, all-time:
  • Site-wide: 5,882 out of 57,506
  • In genomics: 989 out of 4,027
• Year to date:
  • Site-wide: 18,871 out of 57,506
• Since beginning of last month:
  • Site-wide: 30,026 out of 57,506

The whale shark genome reveals how genomic and physiological properties scale with body size

• Downloaded 1,041 times
• Download rankings, all-time:
  • Site-wide: 6,069 out of 57,506
  • In genomics: 1,017 out of 4,027
• Year to date:
  • Site-wide: 3,787 out of 57,506
• Since beginning of last month:
  • Site-wide: 4,671 out of 57,506

Establishing a cell-free Vibrio natriegens expression system

• Downloaded 989 times
• Download rankings, all-time:
  • Site-wide: 6,599 out of 57,506
  • In synthetic biology: 103 out of 550
• Year to date:
  • Site-wide: 12,300 out of 57,506
• Since beginning of last month:
  • Site-wide: 17,494 out of 57,506

Recording temporal data onto DNA with minutes resolution

• Downloaded 987 times
• Download rankings, all-time:
  • Site-wide: 6,611 out of 57,506
  • In synthetic biology: 105 out of 550
• Year to date:
  • Site-wide: 1,092 out of 57,506
• Since beginning of last month:
  • Site-wide: 639 out of 57,506

Biosensor libraries harness large classes of binding domains for allosteric transcription regulators

• Downloaded 960 times
• Download rankings, all-time:
  • Site-wide: 6,908 out of 57,506
  • In synthetic biology: 112 out of 550
• Year to date:
  • Site-wide: 36,448 out of 57,506
• Since beginning of last month:
  • Site-wide: 42,905 out of 57,506

Systemic post-translational control of bacterial metabolism regulates adaptation in dynamic environments

• Downloaded 881 times
• Download rankings, all-time:
  • Site-wide: 7,912 out of 57,506
  • In systems biology: 224 out of 1,638
• Year to date:
  • Site-wide: 13,373 out of 57,506
• Since beginning of last month:
  • Site-wide: 7,564 out of 57,506

Dissecting limiting factors of the Protein synthesis Using Recombinant Elements (PURE) system

• Downloaded 855 times
• Download rankings, all-time:
  • Site-wide: 8,266 out of 57,506
  • In bioengineering: 139 out of 1,103
• Year to date:
  • Site-wide: 54,743 out of 57,506
• Since beginning of last month:
  • Site-wide: 50,655 out of 57,506

Long-term adaptive evolution of genomically recoded Escherichia coli

• Downloaded 768 times
• Download rankings, all-time:
  • Site-wide: 9,765 out of 57,506
  • In evolutionary biology: 672 out of 3,940
• Year to date:
  • Site-wide: 49,156 out of 57,506
• Since beginning of last month:
  • Site-wide: 32,106 out of 57,506

Ethnically relevant consensus Korean reference genome towards personal reference genomes

• Downloaded 688 times
• Download rankings, all-time:
  • Site-wide: 11,407 out of 57,506
  • In genomics: 1,607 out of 4,027
• Year to date:
  • Site-wide: 43,643 out of 57,506
• Since beginning of last month:
  • Site-wide: 40,325 out of 57,506

Spatial Information in Large-Scale Neural Recordings

• Downloaded 646 times
• Download rankings, all-time:
  • Site-wide: 12,477 out of 57,506
  • In neuroscience: 2,022 out of 10,103
• Year to date:
  • Site-wide: 52,323 out of 57,506
• Since beginning of last month:
  • Site-wide: 47,995 out of 57,506

Significant abundance of cis configurations of mutations in diploid human genomes

• Downloaded 623 times
• Download rankings, all-time:
  • Site-wide: 13,070 out of 57,506
  • In genomics: 1,770 out of 4,027
• Year to date:
  • Site-wide: 15,838 out of 57,506
• Since beginning of last month:
  • Site-wide: 15,754 out of 57,506

Cushing's Syndrome mutant PKAL205R exhibits altered substrate specificity

• Downloaded 591 times
• Download rankings, all-time:
  • Site-wide: 14,020 out of 57,506
  • In biochemistry: 278 out of 1,642
• Year to date:
  • Site-wide: 41,754 out of 57,506
• Since beginning of last month:
  • Site-wide: 48,006 out of 57,506

Toward D-Peptide Biosynthesis: Elongation Factor P Enables Ribosomal Incorporation Of Consecutive D-Amino Acids

• Downloaded 582 times
• Download rankings, all-time:
  • Site-wide: 14,350 out of 57,506
  • In biochemistry: 286 out of 1,642
• Year to date:
  • Site-wide: 35,282 out of 57,506
• Since beginning of last month:
  • Site-wide: 29,276 out of 57,506

Millstone: Software for Multiplex Microbial Genome Analysis and Engineering

• Downloaded 546 times
• Download rankings, all-time:
  • Site-wide: 15,651 out of 57,506
  • In synthetic biology: 256 out of 550
• Year to date:
  • Site-wide: 40,571 out of 57,506
• Since beginning of last month:
  • Site-wide: 18,800 out of 57,506

Emergent rules for codon choice elucidated by editing rare arginine codons in Escherichia coli

• Downloaded 439 times
• Download rankings, all-time:
  • Site-wide: 20,388 out of 57,506
  • In genomics: 2,329 out of 4,027
• Year to date:
  • Site-wide: 49,583 out of 57,506
• Since beginning of last month:
  • Site-wide: 53,455 out of 57,506

Simulating serial-target antibacterial drug synergies using flux balance analysis

• Downloaded 413 times
• Download rankings, all-time:
  • Site-wide: 21,777 out of 57,506
  • In systems biology: 661 out of 1,638
• Year to date:
  • Site-wide: 55,011 out of 57,506
• Since beginning of last month:
  • Site-wide: 47,728 out of 57,506

Physiological Assembly Of Functionally Active 30S Ribosomal Subunits From In Vitro Synthesized Parts

• Downloaded 318 times
• Download rankings, all-time:
  • Site-wide: 28,290 out of 57,506
  • In biochemistry: 693 out of 1,642
• Year to date:
  • Site-wide: 50,815 out of 57,506
• Since beginning of last month:
  • Site-wide: 50,695 out of 57,506