Author: Jia Liu

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Preprints

SARS-CoV-2 infection induces sustained humoral immune responses in convalescent patients following symptomatic COVID-19

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  • Site-wide: 1,106
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• Year to date:
  • Site-wide: 4,825
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  • Site-wide: 17,259

Longitudinal characteristics of lymphocyte responses and cytokine profiles in the peripheral blood of SARS-CoV-2 infected patients

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  • Site-wide: 1,386
  • In infectious diseases: 375
• Year to date:
  • Site-wide: 21,636
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  • Site-wide: 34,938

Clinical features and sexual transmission potential of SARS-CoV-2 infected female patients: a descriptive study in Wuhan, China

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  • Site-wide: 1,473
  • In infectious diseases: 387
• Year to date:
  • Site-wide: 4,274
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  • Site-wide: 3,542

Risk Factors Associated with Clinical Outcomes in 323 COVID-19 Patients in Wuhan, China

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  • Site-wide: 2,005
  • In infectious diseases: 472
• Year to date:
  • Site-wide: 15,406
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  • Site-wide: 13,347

Discovery of baicalin and baicalein as novel, natural product inhibitors of SARS-CoV-2 3CL protease in vitro

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  • Site-wide: 2,755
  • In molecular biology: 58
• Year to date:
  • Site-wide: 3,209
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  • Site-wide: 3,194

Trimeric SARS-CoV-2 Spike interacts with dimeric ACE2 with limited intra-Spike avidity

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  • Site-wide: 6,338
  • In biochemistry: 114
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  • Site-wide: 5,094
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  • Site-wide: 5,291

Cyborg Organoids: Implantation of Nanoelectronics via Organogenesis for Tissue-Wide Electrophysiology

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  • Site-wide: 8,258
  • In bioengineering: 135
• Year to date:
  • Site-wide: 16,566
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  • Site-wide: 19,880

SARS-CoV-2-specific T cell memory is long-lasting in the majority of convalsecent COVID-19 individuals

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  • Site-wide: 8,674
  • In microbiology: 498
• Year to date:
  • Site-wide: 9,192
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  • Site-wide: 14,646

Mapping Cortical Brain Asymmetry in 17,141 Healthy Individuals Worldwide via the ENIGMA Consortium

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  • Site-wide: 12,151
  • In neuroscience: 1,352
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  • Site-wide: 91,685
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  • Site-wide: 124,137

The Trans-omics Landscape of COVID-19

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  • Site-wide: 14,983
  • In infectious diseases: 1,509
• Year to date:
  • Site-wide: 17,923
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  • Site-wide: 14,852

Genomic profiling of plasma circulating tumor DNA reveals genetics and residual disease in extranodal NK/T-cell lymphoma

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  • Site-wide: 20,808
  • In genomics: 2,063
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  • Site-wide: 25,388
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  • Site-wide: 24,468

Bi-paratopic and multivalent human VH domains neutralize SARS-CoV-2 by targeting distinct epitopes within the ACE2 binding interface of Spike

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  • Site-wide: 24,514
  • In bioengineering: 412
• Year to date:
  • Site-wide: 29,118
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  • Site-wide: 32,838

Gene Expression Correlates of the Cortical Network Underlying Sentence Processing

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  • Site-wide: 31,172
  • In neuroscience: 4,203
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  • Site-wide: 73,000
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  • Site-wide: 126,403

Allosteric Inhibition of CRISPR-Cas9 by Bacteriophage-derived Peptides

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  • Site-wide: 32,828
  • In genomics: 2,886
• Year to date:
  • Site-wide: 100,651
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  • Site-wide: 94,773

Exosomes exploit the virus entry machinery and pathway to transmit IFN-α-induced antiviral activity.

• Downloaded 665 times
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  • Site-wide: 38,323
  • In microbiology: 2,286
• Year to date:
  • Site-wide: 95,098
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  • Site-wide: 103,131

ClusterMap: multi-scale clustering analysis of spatial gene expression

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  • Site-wide: 42,586
  • In genomics: 3,479
• Year to date:
  • Site-wide: 2,991
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  • Site-wide: 2,526

Impaired cytotoxic CD8+ T cell response in elderly COVID-19 patients

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  • Site-wide: 43,458
  • In immunology: 1,237
• Year to date:
  • Site-wide: 56,077
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  • Site-wide: 71,573

Developmentally Delayed Epigenetic Reprogramming Underlying the Pathogenesis of Preeclampsia

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  • Site-wide: 44,556
  • In genomics: 3,585
• Year to date:
  • Site-wide: 33,746
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  • Site-wide: 47,510

DNNBrain: a unifying toolbox for mapping deep neural networks and brains

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  • Site-wide: 48,189
  • In neuroscience: 6,994
• Year to date:
  • Site-wide: 59,228
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  • Site-wide: 62,430

The face module emerged in a deep convolutional neural network selectively deprived of face experience

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  • Site-wide: 51,068
  • In neuroscience: 7,465
• Year to date:
  • Site-wide: 38,521
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  • Site-wide: 27,250

Structural basis for repurpose and design of nucleoside drugs for treating COVID-19

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  • Site-wide: 57,837
  • In biophysics: 2,013
• Year to date:
  • Site-wide: 17,942
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  • Site-wide: 40,425

Intrinsic Hippocampal-Caudate Interaction Correlates with Human Navigation

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  • Site-wide: 63,458
  • In neuroscience: 9,503
• Year to date:
  • Site-wide: 101,428
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  • Site-wide: 135,634

In situ electro-sequencing in three-dimensional tissues

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  • Site-wide: 72,950
  • In genomics: 4,986
• Year to date:
  • Site-wide: 6,087
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  • Site-wide: 923

An epigenetic LTR-retrotransposon insertion in the upstream region of BnSHP1.A9 controls quantitative pod shattering resistance in Brassica napus

• Downloaded 280 times
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  • Site-wide: 92,007
  • In genetics: 4,108
• Year to date:
  • Site-wide: 110,164
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  • Site-wide: 102,454

Occurrence of COVID-19 symptoms during SARS-CoV-2 infection defines waning of humoral immunity

• Downloaded 279 times
• Download rankings, all-time:
  • Site-wide: 92,134
  • In immunology: 2,633
• Year to date:
  • Site-wide: 9,359
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  • Site-wide: 7,736

Semantic relatedness emerges in deep convolutional neural networks designed for object recognition

• Downloaded 268 times
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  • Site-wide: 94,687
  • In neuroscience: 14,624
• Year to date:
  • Site-wide: 66,327
• Since beginning of last month:
  • Site-wide: 100,132

Surfaceome CRISPR Screen Identifies OLFML3 as a Rhinovirus-inducible IFN Antagonist

• Downloaded 256 times
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  • Site-wide: 97,296
  • In molecular biology: 2,892
• Year to date:
  • Site-wide: 25,381
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  • Site-wide: 14,855

Probing apoptosis signaling proteins in single living cells for precision efficacy evaluation of anti-cancer drugs

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  • Site-wide: 98,509
  • In cancer biology: 2,985
• Year to date:
  • Site-wide: 84,264
• Since beginning of last month:
  • Site-wide: 96,222

Hierarchical sparse coding of objects in deep convolutional neural networks

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  • Site-wide: 102,082
  • In neuroscience: 15,753
• Year to date:
  • Site-wide: 97,478
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  • Site-wide: 69,297

Prophylactic and therapeutic HBV vaccination by an HBs-expressing cytomegalovirus vector lacking an interferon antagonist

• Downloaded 228 times
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  • Site-wide: 103,599
  • In immunology: 2,977
• Year to date:
  • Site-wide: 124,853
• Since beginning of last month:
  • Site-wide: 116,082

Voxel-level forecast system for lesion development in patients with COVID-19

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  • Site-wide: 104,556
  • In radiology and imaging: 191
• Year to date:
  • Site-wide: 26,947
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  • Site-wide: 55,780

A novel blaSIM-1-carrying megaplasmid pSIM-1-BJ01 isolated from clinical Klebsiella pneumonia

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  • Site-wide: 109,495
  • In epidemiology: 4,526
• Year to date:
  • Site-wide: 130,209
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  • Site-wide: 121,123

MetaFunPrimer: primer design for targeting genes observed in metagenomes

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• Download rankings, all-time:
  • Site-wide: 113,253
  • In bioinformatics: 9,375
• Year to date:
  • Site-wide: 49,490
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  • Site-wide: 40,995

Phage Peptides Mediate Precision Base Editing with Focused Targeting Window

• Downloaded 178 times
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  • Site-wide: 114,934
  • In genomics: 6,445
• Year to date:
  • Site-wide: 65,049
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  • Site-wide: 37,994

Impact of genetic susceptibility to multiple sclerosis on the T cell epigenome: proximal and distal effects

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  • Site-wide: 115,299
  • In genomics: 6,454
• Year to date:
  • Site-wide: 73,479
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  • Site-wide: 72,438

Engineering of membrane complex sphingolipids improves osmotic tolerance of Saccharomyces cerevisiae

• Downloaded 173 times
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  • Site-wide: 115,972
  • In bioengineering: 2,272
• Year to date:
  • Site-wide: 117,596
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  • Site-wide: 100,480

dSCOPE: a software to detect sequences critical for liquid-liquid phase separation

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  • Site-wide: 116,075
  • In bioinformatics: 9,526
• Year to date:
  • Site-wide: 17,644
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  • Site-wide: 22,881

Aberrant peripheral immune responses in acute Kawasaki disease with single-cell sequencing

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  • Site-wide: 116,493
  • In immunology: 3,331
• Year to date:
  • Site-wide: 44,996
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  • Site-wide: 40,416

Chinese medicine (Q-14) in the Treatment of Patients with Coronavirus Disease 2019 (COVID-19): A Single-center, Open label, Randomised Controlled Trial

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  • Site-wide: 117,068
  • In infectious diseases: 4,347
• Year to date:
  • Site-wide: 18,385
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  • Site-wide: 32,413

Electroacupuncture at Governor Vessel improves neurobehavioral function via reduction of complexin1

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  • Site-wide: 117,277
  • In neuroscience: 18,063
• Year to date:
  • Site-wide: 110,856
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  • Site-wide: 115,698

Precision Genome and Base Editing by Regulating mRNA Nuclear Export Using Selective Inhibitors of Nuclear Export

• Downloaded 156 times
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  • Site-wide: 119,650
  • In biochemistry: 3,599
• Year to date:
  • Site-wide: 20,210
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  • Site-wide: 3,178

Implementation-independent representation for deep convolutional neural networks and humans in processing faces

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  • Site-wide: 121,083
  • In neuroscience: 18,556
• Year to date:
  • Site-wide: 103,625
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  • Site-wide: 119,090

MicroRNA variants and HLA-miRNA interactions are novel rheumatoid arthritis susceptibility factors

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  • Site-wide: 122,903
  • In genetics: 5,190
• Year to date:
  • Site-wide: 78,180
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  • Site-wide: 64,125

Electrical impedance detection of sickle cell vaso-occlusion in microfluidic capillary structures

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  • Site-wide: 124,095
  • In bioengineering: 2,499
• Year to date:
  • Site-wide: 97,465
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  • Site-wide: 117,163

High-throughput functional characterization of visceral afferents by optical recordings from thoracolumbar and lumbosacral dorsal root ganglions

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  • Site-wide: 125,592
  • In bioengineering: 2,541
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  • Site-wide: 25,814
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  • Site-wide: 76,463

Robust range of auditory periphery development, eye opening, and brain gene expression in Wistar rat pups that experience variation in maternal backgrounds

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  • Site-wide: 125,799
  • In neuroscience: 19,266
• Year to date:
  • Site-wide: 113,180
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  • Site-wide: 78,328

Multidimensional face representation in deep convolutional neural network reveals the mechanism underlying AI racism

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  • Site-wide: 130,192
  • In neuroscience: 19,890
• Year to date:
  • Site-wide: 80,298
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  • Site-wide: 79,687

Fitness benefit plays a vital role in the retention of the Pi-ta susceptible alleles

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  • Site-wide: 133,011
  • In evolutionary biology: 6,663
• Year to date:
  • Site-wide: 117,836
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  • Site-wide: 71,293

Sex difference in hip adduction during the stance phase of running: A swing phase problem?

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  • Site-wide: 134,445
  • In physiology: 1,676
• Year to date:
  • Site-wide: 102,489
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  • Site-wide: 126,655

Longitudinal characterization of phenotypic profile of T cells in chronic hepatitis B identifies immune markers predicting HBsAg loss

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  • Site-wide: 135,351
  • In microbiology: 10,449
• Year to date:
  • Site-wide: 117,998
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  • Site-wide: 118,097

Brain Dynamics of Spatial Reference Frame Proclivity in Active Navigation

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  • Site-wide: 135,946
  • In neuroscience: 20,678
• Year to date:
  • Site-wide: 52,429
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  • Site-wide: 36,705