Author: John R. Mascola

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Preprints

SARS-CoV-2 mRNA Vaccine Development Enabled by Prototype Pathogen Preparedness

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Cryo-EM Structures Delineate a pH-Dependent Switch that Mediates Endosomal Positioning of SARS-CoV-2 Spike Receptor-Binding Domains

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Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1

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Structure-Based Design with Tag-Based Purification and In-Process Biotinylation Enable Streamlined Development of SARS-CoV-2 Spike Molecular Probes

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Elicitation of broadly protective immunity to influenza by multivalent hemagglutinin nanoparticle vaccines

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Accurate Prediction of Antibody Resistance in Clinical HIV-1 Isolates

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Complete functional mapping of infection- and vaccine-elicited antibodies against the fusion peptide of HIV

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Structural survey of HIV-1-neutralizing antibodies targeting Env trimer delineates epitope categories and suggests vaccine templates

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Protection of rhesus macaques against vaginal SHIV challenges by VRC01 and an anti-α4β7 antibody

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A comprehensive influenza reporter virus panel for high-throughput deep profiling of neutralizing antibodies

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A Platform Incorporating Trimeric Antigens into Self-Assembling Nanoparticles Reveals SARS-CoV-2-Spike Nanoparticles to Elicit Substantially Higher Neutralizing Responses than Spike Alone

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Design of nanoparticulate group 2 influenza hemagglutinin stem antigens that activate unmutated ancestor B cell receptors of broadly neutralizing antibody lineages

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Extensive CD8β depletion does not prevent control of viral replication or protection from challenge in macaques chronically infected with a live attenuated simian immunodeficiency virus

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Recapitulation of HIV-1 Env-Antibody Coevolution in Macaques Leading to Neutralization Breadth

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