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Author: John R Mascola

Rankings

  • All-time downloads: 83,748 (rank: 1,594 )
  • Categories:
    • bioinformatics: 1,041 (rank: 13,705 (tie) )
    • immunology: 81,351 (rank: 62 )
    • microbiology: 1,356 (rank: 10,063 (tie) )

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Preprints

Structurally related but genetically unrelated antibody lineages converge on an immunodominantHIV-1 Env neutralizing determinant following trimer immunization

biochemistry more details view paper

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Ultrapotent bispecific antibodies neutralize emerging SARS-CoV-2 variants

immunology more details view paper

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Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7

immunology more details view paper
  • Downloaded 32,905 times
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    • Site-wide: 192
    • In immunology: 9
  • Year to date:
    • Site-wide: 16
  • Since beginning of last month:
    • Site-wide: 25

SARS-CoV-2 mRNA Vaccine Development Enabled by Prototype Pathogen Preparedness

immunology more details view paper
  • Downloaded 28,418 times
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    • Site-wide: 220
    • In immunology: 10
  • Year to date:
    • Site-wide: 240
  • Since beginning of last month:
    • Site-wide: 260

LY-CoV555, a rapidly isolated potent neutralizing antibody, provides protection in a non-human primate model of SARS-CoV-2 infection

immunology more details view paper
  • Downloaded 6,273 times
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    • Site-wide: 1,444
    • In immunology: 33
  • Year to date:
    • Site-wide: 370
  • Since beginning of last month:
    • Site-wide: 517

Cryo-EM Structures Delineate a pH-Dependent Switch that Mediates Endosomal Positioning of SARS-CoV-2 Spike Receptor-Binding Domains

immunology more details view paper
  • Downloaded 4,054 times
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    • Site-wide: 2,662
    • In immunology: 77
  • Year to date:
    • Site-wide: 3,138
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    • Site-wide: 4,495

Elicitation of broadly protective immunity to influenza by multivalent hemagglutinin nanoparticle vaccines

immunology more details view paper
  • Downloaded 1,378 times
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    • Site-wide: 12,934
    • In immunology: 366
  • Year to date:
    • Site-wide: 3,967
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    • Site-wide: 2,470

Real-time Conformational Dynamics of SARS-CoV-2 Spikes on Virus Particles

microbiology more details view paper
  • Downloaded 1,356 times
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    • Site-wide: 13,264
    • In microbiology: 752
  • Year to date:
    • Site-wide: 15,532
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    • Site-wide: 18,808

Structure-Based Design with Tag-Based Purification and In-Process Biotinylation Enable Streamlined Development of SARS-CoV-2 Spike Molecular Probes

immunology more details view paper
  • Downloaded 1,274 times
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    • Site-wide: 14,596
    • In immunology: 419
  • Year to date:
    • Site-wide: 30,006
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    • Site-wide: 41,413

Antibodies with potent and broad neutralizing activity against antigenically diverse and highly transmissible SARS-CoV-2 variants

immunology more details view paper
  • Downloaded 1,249 times
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    • Site-wide: 15,033
    • In immunology: 438
  • Year to date:
    • Site-wide: 799
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    • Site-wide: 530

Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1

immunology more details view paper
  • Downloaded 1,149 times
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    • Site-wide: 17,041
    • In immunology: 496
  • Year to date:
    • Site-wide: 107,792
  • Since beginning of last month:
    • Site-wide: 117,498

A Platform Incorporating Trimeric Antigens into Self-Assembling Nanoparticles Reveals SARS-CoV-2-Spike Nanoparticles to Elicit Substantially Higher Neutralizing Responses than Spike Alone

immunology more details view paper
  • Downloaded 1,131 times
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    • Site-wide: 17,417
    • In immunology: 504
  • Year to date:
    • Site-wide: 15,357
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    • Site-wide: 21,194

A comprehensive influenza reporter virus panel for high-throughput deep profiling of neutralizing antibodies

immunology more details view paper
  • Downloaded 600 times
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    • Site-wide: 42,208
    • In immunology: 1,179
  • Year to date:
    • Site-wide: 16,883
  • Since beginning of last month:
    • Site-wide: 22,547

Accurate Prediction of Antibody Resistance in Clinical HIV-1 Isolates

bioinformatics more details view paper
  • Downloaded 533 times
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    • Site-wide: 48,733
    • In bioinformatics: 5,066
  • Year to date:
    • Site-wide: 90,349
  • Since beginning of last month:
    • Site-wide: 85,846

Structural survey of HIV-1-neutralizing antibodies targeting Env trimer delineates epitope categories and suggests vaccine templates

bioinformatics more details view paper
  • Downloaded 508 times
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    • Site-wide: 51,600
    • In bioinformatics: 5,296
  • Year to date:
    • Site-wide: 73,946
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    • Site-wide: 79,383

Protection of rhesus macaques against vaginal SHIV challenges by VRC01 and an anti-α4β7 antibody

immunology more details view paper
  • Downloaded 476 times
  • Download rankings, all-time:
    • Site-wide: 55,639
    • In immunology: 1,550
  • Year to date:
    • Site-wide: 95,577
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    • Site-wide: 89,890

Complete functional mapping of infection- and vaccine-elicited antibodies against the fusion peptide of HIV

immunology more details view paper
  • Downloaded 470 times
  • Download rankings, all-time:
    • Site-wide: 56,308
    • In immunology: 1,566
  • Year to date:
    • Site-wide: 125,700
  • Since beginning of last month:
    • Site-wide: 122,958

Human antibody immune responses are personalized by selective removal of MHC-II peptide epitopes

immunology more details view paper
  • Downloaded 403 times
  • Download rankings, all-time:
    • Site-wide: 65,919
    • In immunology: 1,823
  • Year to date:
    • Site-wide: 3,745
  • Since beginning of last month:
    • Site-wide: 8,675

Design of nanoparticulate group 2 influenza hemagglutinin stem antigens that activate unmutated ancestor B cell receptors of broadly neutralizing antibody lineages

immunology more details view paper
  • Downloaded 393 times
  • Download rankings, all-time:
    • Site-wide: 67,578
    • In immunology: 1,873
  • Year to date:
    • Site-wide: 73,556
  • Since beginning of last month:
    • Site-wide: 73,617

Recapitulation of HIV-1 Env-Antibody Coevolution in Macaques Leading to Neutralization Breadth

immunology more details view paper
  • Downloaded 393 times
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    • Site-wide: 67,667
    • In immunology: 1,872
  • Year to date:
    • Site-wide: 19,805
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    • Site-wide: 14,827

Isolation and Characterization of Cross-Neutralizing Coronavirus Antibodies from COVID-19+ Subjects

immunology more details view paper
  • Downloaded 332 times
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    • Site-wide: 78,454
    • In immunology: 2,178
  • Year to date:
    • Site-wide: 5,028
  • Since beginning of last month:
    • Site-wide: 1,293

Extensive CD8β depletion does not prevent control of viral replication or protection from challenge in macaques chronically infected with a live attenuated simian immunodeficiency virus

immunology more details view paper
  • Downloaded 279 times
  • Download rankings, all-time:
    • Site-wide: 89,266
    • In immunology: 2,503
  • Year to date:
    • Site-wide: 111,749
  • Since beginning of last month:
    • Site-wide: 115,192

Virus-Like Particle Based-Vaccines Elicit Neutralizing Antibodies against the HIV-1 Fusion Peptide

immunology more details view paper
  • Downloaded 174 times
  • Download rankings, all-time:
    • Site-wide: 112,378
    • In immunology: 3,179
  • Year to date:
    • Site-wide: 75,492
  • Since beginning of last month:
    • Site-wide: 126,407

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