Author: Xi Chen

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Preprints

A rapid and robust method for single cell chromatin accessibility profiling

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Single-cell RNA sequencing reveals a dynamic stromal niche within the evolving tumour microenvironment

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Unsupervised clustering and epigenetic classification of single cells

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Genome-wide CRISPR screens in T helper cells reveal pervasive cross-talk between activation and differentiation

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Detection of complex structural variation from paired-end sequencing data

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Evaluating Protein Transfer Learning with TAPE

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Gene expression variability across cells and species shapes innate immunity

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Assessing real-time Zika risk in the United States

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Structure-Based Design, Synthesis and Biological Evaluation of Peptidomimetic Aldehydes as a Novel Series of Antiviral Drug Candidates Targeting the SARS-CoV-2 Main Protease

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Transcriptome Dynamics Reveals Progressive Transition from Effector to Memory in CD4+ T cells.

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The IRE1a-XBP1 pathway promotes T helper cell differentiation by resolving secretory stress and accelerating proliferation

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Scalable volumetric imaging for ultrahigh-speed brain mapping at synaptic resolution

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Mocap: Large-scale inference of transcription factor binding sites from chromatin accessibility

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Tumors induce de novo steroid biosynthesis in T cells to evade immunity

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pathwayPCA: an R package for integrative pathway analysis with modern PCA methodology and gene selection

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Rora regulates activated T helper cells during inflammation

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Integrative analysis of single cell genomics data by coupled nonnegative matrix factorizations

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12h-clock control of central dogma information flow by XBP1s

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Rap2 and TNIK control Plexin-dependent synaptic tiling in C. elegans

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Spatial Transcriptional Mapping of the Human Nephrogenic Program

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Dual indexed design of in-Drop single-cell RNA-seq libraries improves sequencing quality and throughput

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Cholecystokinin release triggered by presynaptic NMDA receptors produces LTP and sound-sound associative memory formation

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The effects of modified sialic acids on mucus and erythrocytes on influenza A virus HA and NA functions

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Knowledge-guided analysis of 'omics' data using the KnowEnG cloud platform

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coMethDMR: Accurate identification of co-methylated and differentially methylated regions in epigenome-wide association studies

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Quantitative Real-Time Imaging of Glutathione with Sub-Cellular Resolution

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Disentangling the contribution of childhood and adulthood circumstances and genetics to phenotypic aging: prospective cohort study

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Growth Factor Independent 1 is a tumor suppressor gene in colorectal cancer

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Unconsciously Implanted Visuoauditory Memory in the Presence of Cholecystokinin Retrieved in Behavioral Contexts

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Reprogramming the endogenous type III-A CRISPR-Cas system for genome editing, RNA interference and CRISPRi screening in Mycobacterium tuberculosis

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MassComp, a lossless compressor for mass spectrometry data

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Dopaminergic Neurodegeneration Induced by Parkinson's Disease-Linked G2019S LRRK2 is Dependent on Kinase and GTPase Activity

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Alternative splicing and translation play important roles in parallel with transcriptional regulation during rice hypoxic germination

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ChIP-BIT2: a software tool to detect weak binding events using a Bayesian integration approach

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Selectivity and engineering of the sialoglycan-binding spectrum in Siglec-like adhesins

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KAT7 is a therapeutic vulnerability of MLL-rearranged acute myeloid leukemia

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Bayesian inference of differentially expressed transcripts and their abundance from multi-condition RNA-seq data

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MSIGNET: a Metropolis sampling-based method for global optimal significant network identification

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BICORN: An R package for integrative inference of de novo cis-regulatory modules

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GIP: A Gene network-based integrative approach for Inferring disease-associated signaling Pathways

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Impact of Prior Cancer on Outcomes in Nasopharyngeal Carcinoma

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Retrieval Practice Facilitates Judgments of Learning Through Multiple Mechanisms

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Cellular heterogeneity-adjusted clonal methylation (CHALM) provides better prediction of gene expression

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ChIP-GSM: cell type-specific cis-regulatory module inference for active regulatory element prediction

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Lipidomic and Ultrastructural Characterization of Cell Envelope of Staphylococcus aureus Grown in the Presence of Human Serum

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stLFRsv: a germline SV analysis pipeline using co-barcoded reads

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Neuron-glia Integrity: Functional Assessment, Molecular Underpinnings, and Implication for Higher Brain Functions

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Acidosis, Zinc and HMGB1 in Sepsis: A Common Connection Involving Sialoglycan Recognition

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