Author: Daniel J. Rader

Downloads per author, site-wide

Preprints

Genome-wide analysis in 756,646 individuals provides first genetic evidence that ACE2 expression influences COVID-19 risk and yields genetic risk scores predictive of severe disease

• Downloaded 2,551 times
• Download rankings, all-time:
  • Site-wide: 6,197
  • In genetic and genomic medicine: 27
• Year to date:
  • Site-wide: 1,361
• Since beginning of last month:
  • Site-wide: 28,800

Seasonal human coronavirus antibodies are boosted upon SARS-CoV-2 infection but not associated with protection

• Downloaded 2,400 times
• Download rankings, all-time:
  • Site-wide: 6,791
  • In infectious diseases: 1,093
• Year to date:
  • Site-wide: 4,800
• Since beginning of last month:
  • Site-wide: 56,011

A trans-ancestry genome-wide association study of unexplained chronic ALT elevation as a proxy for nonalcoholic fatty liver disease with histological and radiological validation.

• Downloaded 2,015 times
• Download rankings, all-time:
  • Site-wide: 8,753
  • In genetic and genomic medicine: 38
• Year to date:
  • Site-wide: 1,273
• Since beginning of last month:
  • Site-wide: 479

Discovery of 318 novel loci for type-2 diabetes and related micro- and macrovascular outcomes among 1.4 million participants in a multi-ethnic meta-analysis.

• Downloaded 1,679 times
• Download rankings, all-time:
  • Site-wide: 11,447
  • In genetic and genomic medicine: 49
• Year to date:
  • Site-wide: 33,443
• Since beginning of last month:
  • Site-wide: 42,260

SARS-CoV-2 seropositivity and seroconversion in patients undergoing active cancer-directed therapy

• Downloaded 1,666 times
• Download rankings, all-time:
  • Site-wide: 11,594
  • In oncology: 13
• Year to date:
  • Site-wide: 1,638
• Since beginning of last month:
  • Site-wide: 74,210

A Mendelian randomization study of the role of lipoprotein subfractions in coronary artery disease

• Downloaded 1,447 times
• Download rankings, all-time:
  • Site-wide: 14,267
  • In genetics: 651
• Year to date:
  • Site-wide: 15,198
• Since beginning of last month:
  • Site-wide: 66,957

SARS-CoV-2 Seroprevalence Among Parturient Women

• Downloaded 1,246 times
• Download rankings, all-time:
  • Site-wide: 17,877
  • In infectious diseases: 1,837
• Year to date:
  • Site-wide: 33,243
• Since beginning of last month:
  • Site-wide: 33,725

Sero-monitoring of health care workers reveals complex relationships between common coronavirus antibodies and SARS-CoV-2 severity

• Downloaded 1,233 times
• Download rankings, all-time:
  • Site-wide: 18,171
  • In infectious diseases: 1,852
• Year to date:
  • Site-wide: 2,460
• Since beginning of last month:
  • Site-wide: 65,350

Exome-by-phenome-wide rare variant gene burden association with electronic health record phenotypes

• Downloaded 1,002 times
• Download rankings, all-time:
  • Site-wide: 24,631
  • In genomics: 2,305
• Year to date:
  • Site-wide: 30,281
• Since beginning of last month:
  • Site-wide: 11,230

Genome-wide Association Study of Alcohol Consumption and Use Disorder in Multiple Populations (N = 274,424)

• Downloaded 935 times
• Download rankings, all-time:
  • Site-wide: 27,283
  • In genetics: 1,246
• Year to date:
  • Site-wide: 57,175
• Since beginning of last month:
  • Site-wide: 34,561

Atrial Fibrillation Genetic Risk Differentiates Cardioembolic Stroke from other Stroke Subtypes

• Downloaded 861 times
• Download rankings, all-time:
  • Site-wide: 30,630
  • In genetics: 1,405
• Year to date:
  • Site-wide: 85,290
• Since beginning of last month:
  • Site-wide: 76,089

Rare coding variants in 35 genes associate with circulating lipid levels: a multi-ancestry analysis of 170,000 exomes

• Downloaded 848 times
• Download rankings, all-time:
  • Site-wide: 31,250
  • In genetics: 1,439
• Year to date:
  • Site-wide: 7,309
• Since beginning of last month:
  • Site-wide: 3,311

Genetic And Epigenetic Fine Mapping Of Complex Trait Associated Loci In The Human Liver

• Downloaded 769 times
• Download rankings, all-time:
  • Site-wide: 35,825
  • In genetics: 1,627
• Year to date:
  • Site-wide: 144,767
• Since beginning of last month:
  • Site-wide: None

Disrupting upstream translation in mRNAs leads to loss-of-function associated with human disease

• Downloaded 707 times
• Download rankings, all-time:
  • Site-wide: 40,239
  • In genomics: 3,285
• Year to date:
  • Site-wide: 30,814
• Since beginning of last month:
  • Site-wide: 16,757

RNA-binding protein A1CF modulates plasma triglyceride levels through posttranscriptional regulation of stress-induced VLDL secretion

• Downloaded 649 times
• Download rankings, all-time:
  • Site-wide: 44,998
  • In genomics: 3,588
• Year to date:
  • Site-wide: 76,606
• Since beginning of last month:
  • Site-wide: 112,803

Genetic regulatory mechanisms of smooth muscle cells map to coronary artery disease risk loci

• Downloaded 552 times
• Download rankings, all-time:
  • Site-wide: 55,186
  • In genomics: 4,150
• Year to date:
  • Site-wide: 117,357
• Since beginning of last month:
  • Site-wide: 44,742

Polygenic risk of psychiatric disorders exhibits cross-trait associations in electronic health record data

• Downloaded 537 times
• Download rankings, all-time:
  • Site-wide: 56,939
  • In genetics: 2,516
• Year to date:
  • Site-wide: 104,031
• Since beginning of last month:
  • Site-wide: 93,748

Heterozygous ATP-binding Cassette Transporter G5 Gene Deficiency and Risk of Coronary Artery Disease

• Downloaded 459 times
• Download rankings, all-time:
  • Site-wide: 68,020
  • In genetics: 2,993
• Year to date:
  • Site-wide: 87,362
• Since beginning of last month:
  • Site-wide: 22,280

Targeting the Coronavirus Nucleocapsid Protein through GSK-3 Inhibition

• Downloaded 439 times
• Download rankings, all-time:
  • Site-wide: 71,291
  • In infectious diseases: 3,642
• Year to date:
  • Site-wide: 10,986
• Since beginning of last month:
  • Site-wide: 64,983

Genetics of Height and Risk of Atrial Fibrillation: A Mendelian Randomization Study

• Downloaded 414 times
• Download rankings, all-time:
  • Site-wide: 75,524
  • In cardiovascular medicine: 134
• Year to date:
  • Site-wide: 88,841
• Since beginning of last month:
  • Site-wide: 47,547

Multiplexed targeted resequencing identifies coding and regulatory variation underlying phenotypic extremes of HDL-cholesterol in humans

• Downloaded 375 times
• Download rankings, all-time:
  • Site-wide: 82,777
  • In genomics: 5,393
• Year to date:
  • Site-wide: 140,781
• Since beginning of last month:
  • Site-wide: None

Coronary Artery Disease Risk of Familial Hypercholesterolemia Genetic Variants Independent of Historical Cholesterol Exposure

• Downloaded 348 times
• Download rankings, all-time:
  • Site-wide: 88,397
  • In genetic and genomic medicine: 396
• Year to date:
  • Site-wide: 27,706
• Since beginning of last month:
  • Site-wide: 48,828

Genetics of Smoking and Risk of Atherosclerotic Cardiovascular Diseases: A Mendelian Randomization Study

• Downloaded 324 times
• Download rankings, all-time:
  • Site-wide: 93,448
  • In cardiovascular medicine: 189
• Year to date:
  • Site-wide: 93,997
• Since beginning of last month:
  • Site-wide: 58,259

Myeloid Tribbles 1 induces early atherosclerosis via enhanced foam cell expansion

• Downloaded 278 times
• Download rankings, all-time:
  • Site-wide: 104,271
  • In immunology: 3,099
• Year to date:
  • Site-wide: 128,396
• Since beginning of last month:
  • Site-wide: 52,847

Linking abdominal imaging traits to electronic health record phenotypes

• Downloaded 249 times
• Download rankings, all-time:
  • Site-wide: 111,265
  • In radiology and imaging: 219
• Year to date:
  • Site-wide: 62,405
• Since beginning of last month:
  • Site-wide: 55,498

Association of the Transthyretin Variant V122I With Polyneuropathy Among Individuals of African Descent

• Downloaded 240 times
• Download rankings, all-time:
  • Site-wide: 113,576
  • In genetic and genomic medicine: 587
• Year to date:
  • Site-wide: 48,762
• Since beginning of last month:
  • Site-wide: 46,883

ApoC-III helical structure determines its ability to bind plasma lipoproteins and inhibit Lipoprotein Lipase-mediated triglyceride lipolysis.

• Downloaded 234 times
• Download rankings, all-time:
  • Site-wide: 114,987
  • In biochemistry: 3,421
• Year to date:
  • Site-wide: 72,913
• Since beginning of last month:
  • Site-wide: 18,115

Genetic Variation in Blood Pressure and Lifetime Risk of Peripheral Artery Disease: A Mendelian Randomization Study

• Downloaded 222 times
• Download rankings, all-time:
  • Site-wide: 118,141
  • In cardiovascular medicine: 284
• Year to date:
  • Site-wide: 82,241
• Since beginning of last month:
  • Site-wide: 59,238

Multi-trait GWAS of atherosclerosis detects novel pleiotropic loci

• Downloaded 205 times
• Download rankings, all-time:
  • Site-wide: 122,232
  • In genetic and genomic medicine: 645
• Year to date:
  • Site-wide: 31,195
• Since beginning of last month:
  • Site-wide: 68,580

Impact of natural selection on global patterns of genetic variation, and association with clinical phenotypes, at genes involved in SARS-CoV-2 infection.

• Downloaded 181 times
• Download rankings, all-time:
  • Site-wide: 128,036
  • In genetic and genomic medicine: 690
• Year to date:
  • Site-wide: 36,078
• Since beginning of last month:
  • Site-wide: 28,527

A genome-first approach to rare variants in hypertrophic cardiomyopathy genes MYBPC3 and MYH7 in a medical biobank

• Downloaded 104 times
• Download rankings, all-time:
  • Site-wide: 144,636
  • In genetic and genomic medicine: 833
• Year to date:
  • Site-wide: 64,847
• Since beginning of last month:
  • Site-wide: 127,358