Rxivist combines preprints from bioRxiv with data from Twitter to help you find the papers being discussed in your field. Currently indexing 71,037 bioRxiv papers from 309,945 authors.

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Preprints

The Human Cell Atlas

• Downloaded 11,841 times
• Download rankings, all-time:
  • Site-wide: 91 out of 70,927
  • In cell biology: 3 out of 3,477
• Year to date:
  • Site-wide: 21,220 out of 70,927
• Since beginning of last month:
  • Site-wide: 8,300 out of 70,927

Single cell multi-omics profiling reveals a hierarchical epigenetic landscape during mammalian germ layer specification

• Downloaded 5,429 times
• Download rankings, all-time:
  • Site-wide: 400 out of 70,927
  • In developmental biology: 6 out of 2,118
• Year to date:
  • Site-wide: 1,870 out of 70,927
• Since beginning of last month:
  • Site-wide: 655 out of 70,927

Correcting batch effects in single-cell RNA sequencing data by matching mutual nearest neighbours.

• Downloaded 4,860 times
• Download rankings, all-time:
  • Site-wide: 486 out of 70,927
  • In bioinformatics: 99 out of 6,940
• Year to date:
  • Site-wide: 9,926 out of 70,927
• Since beginning of last month:
  • Site-wide: 23,377 out of 70,927

Multi-Omics factor analysis - a framework for unsupervised integration of multi-omic data sets

• Downloaded 4,589 times
• Download rankings, all-time:
  • Site-wide: 552 out of 70,927
  • In bioinformatics: 110 out of 6,940
• Year to date:
  • Site-wide: 37,841 out of 70,927
• Since beginning of last month:
  • Site-wide: 15,677 out of 70,927

scNMT-seq enables joint profiling of chromatin accessibility DNA methylation and transcription in single cells

• Downloaded 4,574 times
• Download rankings, all-time:
  • Site-wide: 554 out of 70,927
  • In genomics: 142 out of 4,728
• Year to date:
  • Site-wide: 21,024 out of 70,927
• Since beginning of last month:
  • Site-wide: 22,079 out of 70,927

RNA-seq gene profiling - a systematic empirical comparison

• Downloaded 3,866 times
• Download rankings, all-time:
  • Site-wide: 777 out of 70,927
  • In bioinformatics: 150 out of 6,940
• Year to date:
  • Site-wide: 18,688 out of 70,927
• Since beginning of last month:
  • Site-wide: 30,428 out of 70,927

iRAP - an integrated RNA-seq Analysis Pipeline

• Downloaded 3,487 times
• Download rankings, all-time:
  • Site-wide: 951 out of 70,927
  • In bioinformatics: 187 out of 6,940
• Year to date:
  • Site-wide: 19,489 out of 70,927
• Since beginning of last month:
  • Site-wide: 15,931 out of 70,927

Distinguishing cells from empty droplets in droplet-based single-cell RNA sequencing data

• Downloaded 3,003 times
• Download rankings, all-time:
  • Site-wide: 1,255 out of 70,927
  • In bioinformatics: 247 out of 6,940
• Year to date:
  • Site-wide: 36,498 out of 70,927
• Since beginning of last month:
  • Site-wide: 16,434 out of 70,927

Scalable latent-factor models applied to single-cell RNA-seq data separate biological drivers from confounding effects

• Downloaded 2,793 times
• Download rankings, all-time:
  • Site-wide: 1,428 out of 70,927
  • In bioinformatics: 283 out of 6,940
• Year to date:
  • Site-wide: 44,090 out of 70,927
• Since beginning of last month:
  • Site-wide: 54,847 out of 70,927

Single-cell RNA-seq of differentiating iPS cells reveals dynamic genetic effects on gene expression

• Downloaded 2,094 times
• Download rankings, all-time:
  • Site-wide: 2,389 out of 70,927
  • In genomics: 497 out of 4,728
• Year to date:
  • Site-wide: 2,924 out of 70,927
• Since beginning of last month:
  • Site-wide: 3,764 out of 70,927

Placozoa and Cnidaria are sister taxa

• Downloaded 2,049 times
• Download rankings, all-time:
  • Site-wide: 2,491 out of 70,927
  • In zoology: 3 out of 365
• Year to date:
  • Site-wide: 11,363 out of 70,927
• Since beginning of last month:
  • Site-wide: 23,280 out of 70,927

Interplay of cis and trans mechanisms driving transcription factor binding and gene expression evolution

• Downloaded 1,752 times
• Download rankings, all-time:
  • Site-wide: 3,235 out of 70,927
  • In genomics: 626 out of 4,728
• Year to date:
  • Site-wide: 47,706 out of 70,927
• Since beginning of last month:
  • Site-wide: 40,878 out of 70,927

Staged developmental mapping and X chromosome transcriptional dynamics during mouse spermatogenesis

• Downloaded 1,411 times
• Download rankings, all-time:
  • Site-wide: 4,708 out of 70,927
  • In developmental biology: 92 out of 2,118
• Year to date:
  • Site-wide: 24,189 out of 70,927
• Since beginning of last month:
  • Site-wide: 9,954 out of 70,927

Detection and removal of barcode swapping in single-cell RNA-seq data

• Downloaded 1,406 times
• Download rankings, all-time:
  • Site-wide: 4,731 out of 70,927
  • In genomics: 841 out of 4,728
• Year to date:
  • Site-wide: 14,854 out of 70,927
• Since beginning of last month:
  • Site-wide: 12,848 out of 70,927

Specificity of RNAi, LNA and CRISPRi as loss-of-function methods in transcriptional analysis

• Downloaded 1,128 times
• Download rankings, all-time:
  • Site-wide: 6,833 out of 70,927
  • In genomics: 1,108 out of 4,728
• Year to date:
  • Site-wide: 33,759 out of 70,927
• Since beginning of last month:
  • Site-wide: 45,102 out of 70,927

MOFA+: a probabilistic framework for comprehensive integration of structured single-cell data

• Downloaded 1,031 times
• Download rankings, all-time:
  • Site-wide: 7,895 out of 70,927
  • In bioinformatics: 1,394 out of 6,940
• Year to date:
  • Site-wide: 787 out of 70,927
• Since beginning of last month:
  • Site-wide: 495 out of 70,927

Beyond comparisons of means: understanding changes in gene expression at the single-cell level

• Downloaded 1,014 times
• Download rankings, all-time:
  • Site-wide: 8,110 out of 70,927
  • In genomics: 1,274 out of 4,728
• Year to date:
  • Site-wide: 63,657 out of 70,927
• Since beginning of last month:
  • Site-wide: 51,975 out of 70,927

Assessing The Reliability Of Spike-In Normalization For Analyses Of Single-Cell RNA Sequencing Data

• Downloaded 928 times
• Download rankings, all-time:
  • Site-wide: 9,402 out of 70,927
  • In bioinformatics: 1,615 out of 6,940
• Year to date:
  • Site-wide: 12,289 out of 70,927
• Since beginning of last month:
  • Site-wide: 30,539 out of 70,927

CellBender remove-background: a deep generative model for unsupervised removal of background noise from scRNA-seq datasets

• Downloaded 879 times
• Download rankings, all-time:
  • Site-wide: 10,221 out of 70,927
  • In bioinformatics: 1,740 out of 6,940
• Year to date:
  • Site-wide: 999 out of 70,927
• Since beginning of last month:
  • Site-wide: 1,504 out of 70,927

Overcoming confounding plate effects in differential expression analyses of single-cell RNA-seq data

• Downloaded 722 times
• Download rankings, all-time:
  • Site-wide: 13,773 out of 70,927
  • In bioinformatics: 2,217 out of 6,940
• Year to date:
  • Site-wide: 64,414 out of 70,927
• Since beginning of last month:
  • Site-wide: 62,261 out of 70,927

A high-content RNAi screen reveals multiple roles for long noncoding RNAs in cell division

• Downloaded 659 times
• Download rankings, all-time:
  • Site-wide: 15,679 out of 70,927
  • In cell biology: 642 out of 3,477
• Year to date:
  • Site-wide: 12,371 out of 70,927
• Since beginning of last month:
  • Site-wide: 12,693 out of 70,927

Robust expression variability testing reveals heterogeneous T cell responses

• Downloaded 639 times
• Download rankings, all-time:
  • Site-wide: 16,405 out of 70,927
  • In bioinformatics: 2,523 out of 6,940
• Year to date:
  • Site-wide: 48,656 out of 70,927
• Since beginning of last month:
  • Site-wide: 64,530 out of 70,927

Structure and evolutionary history of a large family of NLR proteins in the zebrafish

• Downloaded 611 times
• Download rankings, all-time:
  • Site-wide: 17,492 out of 70,927
  • In evolutionary biology: 1,215 out of 4,638
• Year to date:
  • Site-wide: 49,253 out of 70,927
• Since beginning of last month:
  • Site-wide: 48,856 out of 70,927

Whole-body single-cell sequencing of the Platynereis larva reveals a subdivision into apical versus non-apical tissues

• Downloaded 610 times
• Download rankings, all-time:
  • Site-wide: 17,519 out of 70,927
  • In evolutionary biology: 1,220 out of 4,638
• Year to date:
  • Site-wide: 68,594 out of 70,927
• Since beginning of last month:
  • Site-wide: 41,756 out of 70,927

Altered composition of the γδ T cell pool in lymph nodes during ageing enhances tumour growth

• Downloaded 588 times
• Download rankings, all-time:
  • Site-wide: 18,449 out of 70,927
  • In immunology: 344 out of 1,828
• Year to date:
  • Site-wide: 6,198 out of 70,927
• Since beginning of last month:
  • Site-wide: 23,509 out of 70,927

Structure and evolutionary history of a large family of NLR proteins in the zebrafish

• Downloaded 567 times
• Download rankings, all-time:
  • Site-wide: 19,383 out of 70,927
  • In genomics: 2,300 out of 4,728
• Year to date:
  • Site-wide: 59,607 out of 70,927
• Since beginning of last month:
  • Site-wide: 47,207 out of 70,927

Flipping between Polycomb repressed and active transcriptional states introduces noise in gene expression

• Downloaded 557 times
• Download rankings, all-time:
  • Site-wide: 19,839 out of 70,927
  • In genomics: 2,333 out of 4,728
• Year to date:
  • Site-wide: 59,906 out of 70,927
• Since beginning of last month:
  • Site-wide: 45,091 out of 70,927

Investigating higher order interactions in single cell data with scHOT

• Downloaded 543 times
• Download rankings, all-time:
  • Site-wide: 20,536 out of 70,927
  • In bioinformatics: 2,999 out of 6,940
• Year to date:
  • Site-wide: 2,452 out of 70,927
• Since beginning of last month:
  • Site-wide: 1,049 out of 70,927

Rora regulates activated T helper cells during inflammation

• Downloaded 519 times
• Download rankings, all-time:
  • Site-wide: 21,734 out of 70,927
  • In immunology: 417 out of 1,828
• Year to date:
  • Site-wide: 9,112 out of 70,927
• Since beginning of last month:
  • Site-wide: 21,674 out of 70,927