Author: Jian Wang

Downloads per author, site-wide

Preprints

Lactate Increases Stemness of CD8+ T Cells to Augment Anti-Tumor Immunity

No download data for this paper yet.

Temporal dynamics in viral shedding and transmissibility of COVID-19

• Downloaded 36,734 times
• Download rankings, all-time:
  • Site-wide: 213
  • In infectious diseases: 79
• Year to date:
  • Site-wide: 1,242
• Since beginning of last month:
  • Site-wide: 2,281

Large field of view-spatially resolved transcriptomics at nanoscale resolution

• Downloaded 10,016 times
• Download rankings, all-time:
  • Site-wide: 1,045
  • In cell biology: 10
• Year to date:
  • Site-wide: 278
• Since beginning of last month:
  • Site-wide: 373

An exploratory randomized, controlled study on the efficacy and safety of lopinavir/ritonavir or arbidol treating adult patients hospitalized with mild/moderate COVID-19 (ELACOI)

• Downloaded 8,476 times
• Download rankings, all-time:
  • Site-wide: 1,284
  • In infectious diseases: 383
• Year to date:
  • Site-wide: 5,164
• Since beginning of last month:
  • Site-wide: 6,970

Efficient long single molecule sequencing for cost effective and accurate sequencing, haplotyping, and de novo assembly

• Downloaded 6,067 times
• Download rankings, all-time:
  • Site-wide: 1,975
  • In genomics: 161
• Year to date:
  • Site-wide: 20,281
• Since beginning of last month:
  • Site-wide: 25,187

Single-cell atlas of a non-human primate reveals new pathogenic mechanisms of COVID-19

• Downloaded 5,300 times
• Download rankings, all-time:
  • Site-wide: 2,345
  • In cell biology: 33
• Year to date:
  • Site-wide: 3,823
• Since beginning of last month:
  • Site-wide: 6,965

SARS-CoV-2 detection using digital PCR for COVID-19 diagnosis, treatment monitoring and criteria for discharge

• Downloaded 5,130 times
• Download rankings, all-time:
  • Site-wide: 2,457
  • In infectious diseases: 605
• Year to date:
  • Site-wide: 3,870
• Since beginning of last month:
  • Site-wide: 7,793

CoolMPS™: Advanced massively parallel sequencing using antibodies specific to each natural nucleobase

• Downloaded 4,272 times
• Download rankings, all-time:
  • Site-wide: 3,184
  • In genomics: 316
• Year to date:
  • Site-wide: 7,034
• Since beginning of last month:
  • Site-wide: 9,459

Celebrex adjuvant therapy on COVID-19: An experimental study

• Downloaded 3,943 times
• Download rankings, all-time:
  • Site-wide: 3,568
  • In public and global health: 122
• Year to date:
  • Site-wide: 9,740
• Since beginning of last month:
  • Site-wide: 6,724

Multiple approaches for massively parallel sequencing of HCoV-19 (SARS-CoV-2) genomes directly from clinical samples

• Downloaded 2,973 times
• Download rankings, all-time:
  • Site-wide: 5,284
  • In genomics: 528
• Year to date:
  • Site-wide: 36,613
• Since beginning of last month:
  • Site-wide: 114,681

A Single-Cell Immune Atlas of Triple Negative Breast Cancer Reveals Novel Immune Cell Subsets

• Downloaded 2,500 times
• Download rankings, all-time:
  • Site-wide: 6,822
  • In immunology: 237
• Year to date:
  • Site-wide: 13,758
• Since beginning of last month:
  • Site-wide: 14,630

Single-cell screening of SARS-CoV-2 target cells in pets, livestock, poultry and wildlife

• Downloaded 2,370 times
• Download rankings, all-time:
  • Site-wide: 7,356
  • In cell biology: 154
• Year to date:
  • Site-wide: 15,550
• Since beginning of last month:
  • Site-wide: 14,716

Associations of clinical characteristics and antiviral drugs with viral RNA clearance in patients with COVID-19 in Guangzhou, China: a retrospective cohort study

• Downloaded 2,301 times
• Download rankings, all-time:
  • Site-wide: 7,698
  • In infectious diseases: 1,229
• Year to date:
  • Site-wide: 49,442
• Since beginning of last month:
  • Site-wide: 49,759

Rapid Automated Large Structural Variation Detection in a Diploid Genome by NanoChannel Based Next-Generation Mapping

• Downloaded 2,073 times
• Download rankings, all-time:
  • Site-wide: 8,921
  • In genomics: 896
• Year to date:
  • Site-wide: 65,783
• Since beginning of last month:
  • Site-wide: 56,928

A multi-omic cohort as a reference point for promoting a healthy human gut microbiome

• Downloaded 2,037 times
• Download rankings, all-time:
  • Site-wide: 9,167
  • In microbiology: 543
• Year to date:
  • Site-wide: 24,822
• Since beginning of last month:
  • Site-wide: 25,138

Critical Care for Patients with Severe Covid-2019 in Sichuan Province, China: Provincial Cohort Study

• Downloaded 1,960 times
• Download rankings, all-time:
  • Site-wide: 9,667
  • In intensive care and critical care medicine: 45
• Year to date:
  • Site-wide: 33,308
• Since beginning of last month:
  • Site-wide: 22,764

The HLA Ligand Atlas. A resource of natural HLA ligands presented on benign tissues.

• Downloaded 1,911 times
• Download rankings, all-time:
  • Site-wide: 10,062
  • In immunology: 347
• Year to date:
  • Site-wide: 14,797
• Since beginning of last month:
  • Site-wide: 15,627

Single-cell Transcriptomic Landscape of Nucleated Cells in Umbilical Cord Blood

• Downloaded 1,849 times
• Download rankings, all-time:
  • Site-wide: 10,580
  • In genomics: 1,058
• Year to date:
  • Site-wide: 74,309
• Since beginning of last month:
  • Site-wide: 128,617

Reliable Multiplex Sequencing with Rare Index Mis-Assignment on DNB-Based NGS Platform

• Downloaded 1,819 times
• Download rankings, all-time:
  • Site-wide: 10,842
  • In genomics: 1,093
• Year to date:
  • Site-wide: 62,275
• Since beginning of last month:
  • Site-wide: 77,828

Initial Study of Human Genetic Contribution to COVID-19 Severity and Susceptibility

• Downloaded 1,786 times
• Download rankings, all-time:
  • Site-wide: 11,128
  • In genetic and genomic medicine: 47
• Year to date:
  • Site-wide: 18,283
• Since beginning of last month:
  • Site-wide: 28,689

Recent origin of an XX/XY sex-determination system in the ancient plant lineage Ginkgo biloba

• Downloaded 1,717 times
• Download rankings, all-time:
  • Site-wide: 11,808
  • In evolutionary biology: 354
• Year to date:
  • Site-wide: 13,104
• Since beginning of last month:
  • Site-wide: 7,767

PIRD: Pan immune repertoire database

• Downloaded 1,707 times
• Download rankings, all-time:
  • Site-wide: 11,888
  • In immunology: 400
• Year to date:
  • Site-wide: 18,005
• Since beginning of last month:
  • Site-wide: 25,232

The Trans-omics Landscape of COVID-19

• Downloaded 1,431 times
• Download rankings, all-time:
  • Site-wide: 15,497
  • In infectious diseases: 1,768
• Year to date:
  • Site-wide: 23,620
• Since beginning of last month:
  • Site-wide: 63,404

A new massively parallel nanoball sequencing platform for whole exome research

• Downloaded 1,377 times
• Download rankings, all-time:
  • Site-wide: 16,456
  • In genomics: 1,601
• Year to date:
  • Site-wide: 97,376
• Since beginning of last month:
  • Site-wide: 122,471

Gene Panel Sequencing in a Chinese High-risk Breast Cancer Cohort

• Downloaded 1,368 times
• Download rankings, all-time:
  • Site-wide: 16,619
  • In cancer biology: 357
• Year to date:
  • Site-wide: 27,321
• Since beginning of last month:
  • Site-wide: 16,555

Circularization of genes and chromosome by CRISPR in human cells

• Downloaded 1,364 times
• Download rankings, all-time:
  • Site-wide: 16,690
  • In genomics: 1,620
• Year to date:
  • Site-wide: 83,645
• Since beginning of last month:
  • Site-wide: 111,041

Fecal microbiota transplantation brings about bacterial strain displacement in patients with inflammatory bowel diseases

• Downloaded 1,335 times
• Download rankings, all-time:
  • Site-wide: 17,231
  • In clinical trials: 39
• Year to date:
  • Site-wide: 26,932
• Since beginning of last month:
  • Site-wide: 86,931

Over 50000 metagenomically assembled draft genomes for the human oral microbiome reveal new taxa

• Downloaded 1,319 times
• Download rankings, all-time:
  • Site-wide: 17,534
  • In microbiology: 1,021
• Year to date:
  • Site-wide: 27,102
• Since beginning of last month:
  • Site-wide: 25,279

Characterization of Microbial Co-infections in the Respiratory Tract of hospitalized COVID-19 patients

• Downloaded 1,302 times
• Download rankings, all-time:
  • Site-wide: 17,867
  • In infectious diseases: 1,894
• Year to date:
  • Site-wide: 20,131
• Since beginning of last month:
  • Site-wide: 25,294

A catalog of microbial genes from the bovine rumen unveils a specialized and diverse biomass-degrading environment

• Downloaded 1,261 times
• Download rankings, all-time:
  • Site-wide: 18,735
  • In microbiology: 1,092
• Year to date:
  • Site-wide: 104,032
• Since beginning of last month:
  • Site-wide: 152,633

Life history recorded in the vagino-cervical microbiome

• Downloaded 1,256 times
• Download rankings, all-time:
  • Site-wide: 18,854
  • In microbiology: 1,101
• Year to date:
  • Site-wide: 61,031
• Since beginning of last month:
  • Site-wide: 72,681

Gene-centric intra- and inter-clade recombination in a context of Escherichia coli subpopulations

• Downloaded 1,219 times
• Download rankings, all-time:
  • Site-wide: 19,708
  • In microbiology: 1,151
• Year to date:
  • Site-wide: 72,587
• Since beginning of last month:
  • Site-wide: 61,102

Massively parallel quantification of CRISPR editing in cells by TRAP-seq enables better design of Cas9, ABE, CBE gRNAs of high efficiency and accuracy

• Downloaded 1,212 times
• Download rankings, all-time:
  • Site-wide: 19,881
  • In systems biology: 372
• Year to date:
  • Site-wide: 35,824
• Since beginning of last month:
  • Site-wide: 41,225

Single-cell RNA-seq reveals distinct dynamic behavior of sex chromosomes during early human embryogenesis

• Downloaded 1,157 times
• Download rankings, all-time:
  • Site-wide: 21,292
  • In developmental biology: 354
• Year to date:
  • Site-wide: 35,328
• Since beginning of last month:
  • Site-wide: 32,786

Small effect size leads to reproducibility failure in resting-state fMRI studies

• Downloaded 1,071 times
• Download rankings, all-time:
  • Site-wide: 23,865
  • In neuroscience: 2,924
• Year to date:
  • Site-wide: 67,304
• Since beginning of last month:
  • Site-wide: 61,427

Intra-host Variation and Evolutionary Dynamics of SARS-CoV-2 Population in COVID-19 Patients

• Downloaded 1,049 times
• Download rankings, all-time:
  • Site-wide: 24,640
  • In genomics: 2,281
• Year to date:
  • Site-wide: 54,486
• Since beginning of last month:
  • Site-wide: 79,271

Enhance genome editing efficiency and specificity by a quick CRISPR/Cas9 system

• Downloaded 1,029 times
• Download rankings, all-time:
  • Site-wide: 25,360
  • In genetics: 1,130
• Year to date:
  • Site-wide: 35,859
• Since beginning of last month:
  • Site-wide: 27,269

Identification of gut microbiome markers for schizophrenia delineates a potential role of Streptococcus

• Downloaded 996 times
• Download rankings, all-time:
  • Site-wide: 26,603
  • In microbiology: 1,558
• Year to date:
  • Site-wide: 43,283
• Since beginning of last month:
  • Site-wide: 49,921

Integration of gut microbiome, host biomarkers, and urine metabolome data reveals networks of interactions associated with distinct clinical phenotypes

• Downloaded 986 times
• Download rankings, all-time:
  • Site-wide: 27,053
  • In microbiology: 1,578
• Year to date:
  • Site-wide: 62,336
• Since beginning of last month:
  • Site-wide: 61,623

Base editing in Streptomyces with Cas9-deaminase fusions

• Downloaded 950 times
• Download rankings, all-time:
  • Site-wide: 28,514
  • In microbiology: 1,675
• Year to date:
  • Site-wide: 45,533
• Since beginning of last month:
  • Site-wide: 31,446

Integrated Analysis Revealed Hub Genes in Breast Cancer

• Downloaded 868 times
• Download rankings, all-time:
  • Site-wide: 32,410
  • In bioinformatics: 3,579
• Year to date:
  • Site-wide: 144,474
• Since beginning of last month:
  • Site-wide: 109,532

The mitochondrial DNA content can not predict the embryo viability

• Downloaded 830 times
• Download rankings, all-time:
  • Site-wide: 34,477
  • In ecology: 721
• Year to date:
  • Site-wide: 69,598
• Since beginning of last month:
  • Site-wide: 71,450

Age-dependent sexual dimorphism in the adult human gut microbiota

• Downloaded 828 times
• Download rankings, all-time:
  • Site-wide: 34,595
  • In genomics: 2,920
• Year to date:
  • Site-wide: 88,947
• Since beginning of last month:
  • Site-wide: 92,893

The landscape of somatic mutation in sporadic Chinese colorectal cancer

• Downloaded 821 times
• Download rankings, all-time:
  • Site-wide: 35,023
  • In genomics: 2,943
• Year to date:
  • Site-wide: 124,319
• Since beginning of last month:
  • Site-wide: 139,945

Time-series plasma cell-free DNA analysis reveals disease severity of COVID-19 patients

• Downloaded 798 times
• Download rankings, all-time:
  • Site-wide: 36,497
  • In epidemiology: 1,901
• Year to date:
  • Site-wide: 39,767
• Since beginning of last month:
  • Site-wide: 33,182

A chromosome-level genome of black rockfish, Sebastes schlegelii, provides insights into the evolution of live birth

• Downloaded 794 times
• Download rankings, all-time:
  • Site-wide: 36,813
  • In genomics: 3,050
• Year to date:
  • Site-wide: 104,029
• Since beginning of last month:
  • Site-wide: 92,496

PALM-Seq: simultaneous sequencing of cell-free long RNA and small RNA

• Downloaded 792 times
• Download rankings, all-time:
  • Site-wide: 36,935
  • In molecular biology: 1,032
• Year to date:
  • Site-wide: 50,147
• Since beginning of last month:
  • Site-wide: 43,332

Impact of anxiety associated with COVID 19 on tinnitus

• Downloaded 787 times
• Download rankings, all-time:
  • Site-wide: 37,275
  • In otolaryngology: 23
• Year to date:
  • Site-wide: 34,944
• Since beginning of last month:
  • Site-wide: 46,664

Engineering of Chimeric Antigen Receptor T Cells with integrin αEβ7 Results in Augmented Therapeutic Efficacy against E-cadherin positive tumor

• Downloaded 774 times
• Download rankings, all-time:
  • Site-wide: 38,100
  • In immunology: 1,217
• Year to date:
  • Site-wide: 35,343
• Since beginning of last month:
  • Site-wide: 49,177

Draft genome sequence of the Solanum aethiopicum provides insights into disease resistance, drought tolerance and the evolution of the genome

• Downloaded 764 times
• Download rankings, all-time:
  • Site-wide: 38,872
  • In genomics: 3,168
• Year to date:
  • Site-wide: 116,706
• Since beginning of last month:
  • Site-wide: 110,581

Calorie restriction intervention induces enterotype-associated BMI loss in nonobese individuals

• Downloaded 734 times
• Download rankings, all-time:
  • Site-wide: 41,035
  • In microbiology: 2,454
• Year to date:
  • Site-wide: 79,582
• Since beginning of last month:
  • Site-wide: 85,034

M-GWAS for the gut microbiome in Chinese adults illuminates on complex diseases

• Downloaded 721 times
• Download rankings, all-time:
  • Site-wide: 42,018
  • In genetics: 1,852
• Year to date:
  • Site-wide: 53,042
• Since beginning of last month:
  • Site-wide: 25,130

Identification of Variable and Joining germline genes and alleles for Rhesus macaque from B-cell receptor repertoires

• Downloaded 699 times
• Download rankings, all-time:
  • Site-wide: 43,862
  • In immunology: 1,386
• Year to date:
  • Site-wide: 95,123
• Since beginning of last month:
  • Site-wide: 152,930

Dynamic chromosome rearrangements of the white-spotted bamboo shark shed light on cartilaginous fish diversification mechanisms

• Downloaded 693 times
• Download rankings, all-time:
  • Site-wide: 44,314
  • In genomics: 3,501
• Year to date:
  • Site-wide: 99,617
• Since beginning of last month:
  • Site-wide: 85,014

St. Jude Cloud a Pediatric Cancer Genomic Data Sharing Ecosystem

• Downloaded 648 times
• Download rankings, all-time:
  • Site-wide: 48,398
  • In cancer biology: 1,363
• Year to date:
  • Site-wide: 56,493
• Since beginning of last month:
  • Site-wide: 74,621

TCR repertoire analysis reveals effector memory T cells differentiation into Th17 cells in rheumatoid arthritis

• Downloaded 640 times
• Download rankings, all-time:
  • Site-wide: 49,227
  • In immunology: 1,516
• Year to date:
  • Site-wide: 80,712
• Since beginning of last month:
  • Site-wide: 118,225

Nationwide population genetic screening improves outcomes of newborn screening for hearing loss in China

• Downloaded 618 times
• Download rankings, all-time:
  • Site-wide: 51,562
  • In genetics: 2,236
• Year to date:
  • Site-wide: 108,148
• Since beginning of last month:
  • Site-wide: 128,310

Ten-eleven translocation 1 Mediated-DNA Hydroxymethylation is Required for Myelination and Remyelination in the Mouse Brain

• Downloaded 592 times
• Download rankings, all-time:
  • Site-wide: 54,436
  • In neuroscience: 7,704
• Year to date:
  • Site-wide: 31,595
• Since beginning of last month:
  • Site-wide: 43,843

The female urinary microbiota in relation to the reproductive tract microbiota

• Downloaded 590 times
• Download rankings, all-time:
  • Site-wide: 54,686
  • In microbiology: 3,407
• Year to date:
  • Site-wide: 53,036
• Since beginning of last month:
  • Site-wide: 43,398

The Clinical Genome Resource (ClinGen) Familial Hypercholesterolemia Variant Curation Expert Panel consensus guidelines for LDLR variant classification

• Downloaded 582 times
• Download rankings, all-time:
  • Site-wide: 55,684
  • In genetic and genomic medicine: 246
• Year to date:
  • Site-wide: 9,726
• Since beginning of last month:
  • Site-wide: 8,583

Spreading predictability in complex networks

• Downloaded 577 times
• Download rankings, all-time:
  • Site-wide: 56,287
  • In bioinformatics: 5,613
• Year to date:
  • Site-wide: 98,412
• Since beginning of last month:
  • Site-wide: 95,267

Smartphone overuse and visual impairment in children and young adults: a systematic review and meta-analysis

• Downloaded 480 times
• Download rankings, all-time:
  • Site-wide: 69,739
  • In ophthalmology: 45
• Year to date:
  • Site-wide: 54,671
• Since beginning of last month:
  • Site-wide: 35,920

Prefusion spike protein stabilization through computational mutagenesis

• Downloaded 479 times
• Download rankings, all-time:
  • Site-wide: 69,828
  • In biophysics: 2,479
• Year to date:
  • Site-wide: 95,772
• Since beginning of last month:
  • Site-wide: 96,858

Insulin/IGF signaling and TOR promote vitellogenesis via inducing juvenile hormone biosynthesis

• Downloaded 466 times
• Download rankings, all-time:
  • Site-wide: 71,959
  • In developmental biology: 1,811
• Year to date:
  • Site-wide: 99,328
• Since beginning of last month:
  • Site-wide: 125,384

Mendelian randomization analyses support causal relationships between blood metabolites and the gut microbiome

• Downloaded 443 times
• Download rankings, all-time:
  • Site-wide: 75,791
  • In genetics: 3,258
• Year to date:
  • Site-wide: 43,493
• Since beginning of last month:
  • Site-wide: 41,403

SingleChannelNet: A Model for Automatic Sleep Stage Classification with Raw Single-Channel EEG

• Downloaded 435 times
• Download rankings, all-time:
  • Site-wide: 77,231
  • In bioengineering: 1,443
• Year to date:
  • Site-wide: 27,454
• Since beginning of last month:
  • Site-wide: 31,595

Detection of Ovarian Cancer Using Samples Sourced from the Vaginal Microenvironment

• Downloaded 424 times
• Download rankings, all-time:
  • Site-wide: 79,293
  • In cancer biology: 2,324
• Year to date:
  • Site-wide: 102,841
• Since beginning of last month:
  • Site-wide: 118,399

Distinct gut metagenomics and metaproteomics signatures in prediabetics and treatment-naïve type 2 diabetics

• Downloaded 406 times
• Download rankings, all-time:
  • Site-wide: 82,750
  • In microbiology: 5,563
• Year to date:
  • Site-wide: 149,273
• Since beginning of last month:
  • Site-wide: 119,901

Sequencing of the MHC region defines HLA-DQA1 as the major independent risk for anti-citrullinated protein antibodies (ACPA)-positive rheumatoid arthritis in Han population

• Downloaded 402 times
• Download rankings, all-time:
  • Site-wide: 83,562
  • In genetics: 3,576
• Year to date:
  • Site-wide: 120,270
• Since beginning of last month:
  • Site-wide: 101,437

Cdc42 is required for lymphatic branching, maturation and valve formation during embryonic development

• Downloaded 392 times
• Download rankings, all-time:
  • Site-wide: 85,500
  • In developmental biology: 2,228
• Year to date:
  • Site-wide: 82,330
• Since beginning of last month:
  • Site-wide: 58,588

The Amyloid Structure of Mouse RIPK3 (Receptor Interacting Protein Kinase 3) in Cell Necroptosis

• Downloaded 388 times
• Download rankings, all-time:
  • Site-wide: 86,416
  • In biochemistry: 2,449
• Year to date:
  • Site-wide: 71,588
• Since beginning of last month:
  • Site-wide: 80,396

Reference genomes of 545 silkworms enable high-throughput exploring genotype-phenotype relationships

• Downloaded 385 times
• Download rankings, all-time:
  • Site-wide: 86,922
  • In genomics: 5,582
• Year to date:
  • Site-wide: 18,016
• Since beginning of last month:
  • Site-wide: 1,065

New genetic variants associated with major adverse cardiovascular events in patients with acute coronary syndromes and treated with clopidogrel and aspirin

• Downloaded 372 times
• Download rankings, all-time:
  • Site-wide: 89,692
  • In genetics: 3,822
• Year to date:
  • Site-wide: 123,949
• Since beginning of last month:
  • Site-wide: 116,818

EpicPCR-Directed Cultivation of a Candidatus Saccharibacteria Symbiont Reveals a Type IV Pili-dependent Epibiotic Lifestyle

• Downloaded 356 times
• Download rankings, all-time:
  • Site-wide: 93,133
  • In microbiology: 6,424
• Year to date:
  • Site-wide: 20,208
• Since beginning of last month:
  • Site-wide: 19,290

Tau Accumulation via Reduced BAG3-mediated Autophagy Is Required for GGGGCC Repeat Expansion-Induced Neurodegeneration

• Downloaded 347 times
• Download rankings, all-time:
  • Site-wide: 95,321
  • In neuroscience: 14,137
• Year to date:
  • Site-wide: 97,742
• Since beginning of last month:
  • Site-wide: 78,109

The landscape and diagnostic potential of T and B cell repertoire in Immunoglobulin A Nephropathy

• Downloaded 344 times
• Download rankings, all-time:
  • Site-wide: 96,005
  • In immunology: 2,874
• Year to date:
  • Site-wide: 139,906
• Since beginning of last month:
  • Site-wide: 148,634

Genomic epidemiology of SARS-CoV-2 in the United Arab Emirates reveals novel virus mutation, patterns of co-infection and tissue specific host innate immune response

• Downloaded 332 times
• Download rankings, all-time:
  • Site-wide: 98,656
  • In epidemiology: 4,198
• Year to date:
  • Site-wide: 22,388
• Since beginning of last month:
  • Site-wide: 52,233

SOAPTyping: an open-source and cross-platform tool for Sanger sequence-based typing for HLA class I and II alleles

• Downloaded 324 times
• Download rankings, all-time:
  • Site-wide: 100,606
  • In bioinformatics: 8,632
• Year to date:
  • Site-wide: 137,892
• Since beginning of last month:
  • Site-wide: 154,199

Expression, Purification, and Functional Reconstitution of 19F-labeled Cytochrome b5 in Peptide Nanodiscs for NMR Studies

• Downloaded 313 times
• Download rankings, all-time:
  • Site-wide: 103,366
  • In biochemistry: 3,019
• Year to date:
  • Site-wide: 88,375
• Since beginning of last month:
  • Site-wide: 130,650

A yeast BiFC-seq method for genome-wide interactome mapping

• Downloaded 296 times
• Download rankings, all-time:
  • Site-wide: 107,364
  • In genomics: 6,318
• Year to date:
  • Site-wide: 78,426
• Since beginning of last month:
  • Site-wide: 95,430

WinnerTakeAlmostAll: A parsimony approach integrating multi-targets improves marker gene profiling

• Downloaded 290 times
• Download rankings, all-time:
  • Site-wide: 109,020
  • In bioinformatics: 9,130
• Year to date:
  • Site-wide: 134,478
• Since beginning of last month:
  • Site-wide: 154,177

TGF-beta promotes microtube formation in glioblastoma through Thrombospondin 1

• Downloaded 270 times
• Download rankings, all-time:
  • Site-wide: 114,137
  • In cancer biology: 3,474
• Year to date:
  • Site-wide: 29,738
• Since beginning of last month:
  • Site-wide: 31,293

A Chinese host genetic study discovered type I interferons and causality of cholesterol levels and WBC counts on COVID-19 severity

• Downloaded 261 times
• Download rankings, all-time:
  • Site-wide: 116,516
  • In genetic and genomic medicine: 632
• Year to date:
  • Site-wide: 31,040
• Since beginning of last month:
  • Site-wide: 48,931

Yuel: Compound-Protein Interaction Prediction with High Generalizability

• Downloaded 258 times
• Download rankings, all-time:
  • Site-wide: 117,222
  • In bioinformatics: 9,620
• Year to date:
  • Site-wide: 31,496
• Since beginning of last month:
  • Site-wide: 14,054

Metagenome-genome-wide association studies reveal human genetic impact on the oral microbiome

• Downloaded 256 times
• Download rankings, all-time:
  • Site-wide: 117,681
  • In genetics: 4,855
• Year to date:
  • Site-wide: 31,945
• Since beginning of last month:
  • Site-wide: 23,804

Maternal perception of child weight and concern about child overweight mediates the relationship between child weight and non-responsive feeding practices

• Downloaded 255 times
• Download rankings, all-time:
  • Site-wide: 117,850
  • In pediatrics: 192
• Year to date:
  • Site-wide: 51,013
• Since beginning of last month:
  • Site-wide: 50,544

Integrative framework of cross-module deep biomarker for the prognosis of clear cell renal cell carcinoma: A retrospective TCGA project

• Downloaded 250 times
• Download rankings, all-time:
  • Site-wide: 119,137
  • In bioinformatics: 9,736
• Year to date:
  • Site-wide: 144,227
• Since beginning of last month:
  • Site-wide: 147,439

Personalized vagino-cervical microbiome dynamics after oral probiotics

• Downloaded 242 times
• Download rankings, all-time:
  • Site-wide: 121,343
  • In microbiology: 8,794
• Year to date:
  • Site-wide: 86,425
• Since beginning of last month:
  • Site-wide: 78,962

Chinese medicine (Q-14) in the Treatment of Patients with Coronavirus Disease 2019 (COVID-19): A Single-center, Open label, Randomised Controlled Trial

• Downloaded 240 times
• Download rankings, all-time:
  • Site-wide: 121,963
  • In infectious diseases: 5,159
• Year to date:
  • Site-wide: 34,657
• Since beginning of last month:
  • Site-wide: 64,139

Various miRNAs are involved in efficient HCV replication

• Downloaded 216 times
• Download rankings, all-time:
  • Site-wide: 128,048
  • In microbiology: 9,411
• Year to date:
  • Site-wide: 126,242
• Since beginning of last month:
  • Site-wide: 95,671

Src/FAK complex phosphorylates cardiac myosin binding protein c (cMyBP-C) in vitro and in vivo

• Downloaded 214 times
• Download rankings, all-time:
  • Site-wide: 128,781
  • In molecular biology: 3,827
• Year to date:
  • Site-wide: 104,789
• Since beginning of last month:
  • Site-wide: 95,402

NeuralDock: Rapid and conformation-agnostic docking of small molecules

• Downloaded 203 times
• Download rankings, all-time:
  • Site-wide: 131,354
  • In biophysics: 5,021
• Year to date:
  • Site-wide: 42,459
• Since beginning of last month:
  • Site-wide: 18,161

Evaluation method of ecosystem service value under complex ecological environment: A case study of Gansu Province, China

• Downloaded 184 times
• Download rankings, all-time:
  • Site-wide: 136,187
  • In ecology: 4,617
• Year to date:
  • Site-wide: 78,265
• Since beginning of last month:
  • Site-wide: 54,166

JAK/STAT pathway promotes Drosophila neuroblast proliferation via the direct CycE regulation

• Downloaded 172 times
• Download rankings, all-time:
  • Site-wide: 139,130
  • In developmental biology: 3,733
• Year to date:
  • Site-wide: 95,402
• Since beginning of last month:
  • Site-wide: 115,326

Fibroblast growth factor-2 prevents synaptic pathology in minimal hepatic encephalopathy via NRG1/ErbB4 signaling

• Downloaded 172 times
• Download rankings, all-time:
  • Site-wide: 139,049
  • In neuroscience: 20,810
• Year to date:
  • Site-wide: 141,972
• Since beginning of last month:
  • Site-wide: 143,874

Comprehensive genome sequencing analysis as a promising option in the prenatal diagnosis of fetal structural anomalies: a prospective study.

• Downloaded 169 times
• Download rankings, all-time:
  • Site-wide: 139,726
  • In genomics: 7,315
• Year to date:
  • Site-wide: 127,777
• Since beginning of last month:
  • Site-wide: 59,261

The inverse relationship between fibronectin and neuroligins in the embryonic rat colon

• Downloaded 156 times
• Download rankings, all-time:
  • Site-wide: 142,497
  • In cell biology: 6,543
• Year to date:
  • Site-wide: 149,557
• Since beginning of last month:
  • Site-wide: 124,911

Plasma cell-free DNA promise disease monitoring and tissue injury assessment of COVID-19

• Downloaded 144 times
• Download rankings, all-time:
  • Site-wide: 145,192
  • In genetic and genomic medicine: 854
• Year to date:
  • Site-wide: 61,975
• Since beginning of last month:
  • Site-wide: 45,157

Microfluidic Streptomyces Cultivation for Whole Lifecycle Characterization and Phenotypic Assays Enabled by Nanogap-stabilized Air-Water Interface

• Downloaded 144 times
• Download rankings, all-time:
  • Site-wide: 145,221
  • In developmental biology: 3,866
• Year to date:
  • Site-wide: 62,010
• Since beginning of last month:
  • Site-wide: 45,201

Transcriptional and Post-transcriptional Regulation of Ethylene Biosynthesis by Salicyclic Acid in Kiwifruit

• Downloaded 102 times
• Download rankings, all-time:
  • Site-wide: 152,859
  • In plant biology: 4,292
• Year to date:
  • Site-wide: 85,037
• Since beginning of last month:
  • Site-wide: 83,170

GM1 mediates the formation and maintenance of cytotoxic Aβ oligomers

• Downloaded 101 times
• Download rankings, all-time:
  • Site-wide: 153,078
  • In biophysics: 5,872
• Year to date:
  • Site-wide: 85,962
• Since beginning of last month:
  • Site-wide: 48,955

Evolutionary trajectories and transmission dynamics of multidrug-resistant Mycobacterium tuberculosis in Tibet, China

• Downloaded 75 times
• Download rankings, all-time:
  • Site-wide: 156,314
  • In infectious diseases: 6,210
• Year to date:
  • Site-wide: 107,198
• Since beginning of last month:
  • Site-wide: 116,375

Temperature Evolution Following Joint Loading Promotes Chondrogenesis by Synergistic Cues via Calcium Signaling

• Downloaded 57 times
• Download rankings, all-time:
  • Site-wide: 157,817
  • In bioengineering: 3,316
• Year to date:
  • Site-wide: 125,923
• Since beginning of last month:
  • Site-wide: 65,622