Rxivist combines preprints from bioRxiv with data from Twitter to help you find the papers being discussed in your field. Currently indexing 74,055 bioRxiv papers from 322,218 authors.

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Preprints

CoolMPS™: Advanced massively parallel sequencing using antibodies specific to each natural nucleobase

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Efficient long single molecule sequencing for cost effective and accurate sequencing, haplotyping, and de novo assembly

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Rapid Automated Large Structural Variation Detection in a Diploid Genome by NanoChannel Based Next-Generation Mapping

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  • In genomics: 660 out of 4,902
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Single-cell Transcriptomic Landscape of Nucleated Cells in Umbilical Cord Blood

• Downloaded 1,489 times
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  • In genomics: 809 out of 4,902
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Reliable Multiplex Sequencing with Rare Index Mis-Assignment on DNB-Based NGS Platform

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• Year to date:
  • Site-wide: 18,762 out of 74,094
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A Single-Cell Immune Atlas of Triple Negative Breast Cancer Reveals Novel Immune Cell Subsets

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  • In immunology: 99 out of 1,947
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A multi-omic cohort as a reference point for promoting a healthy human gut microbiome

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  • In microbiology: 247 out of 6,053
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Circularization of genes and chromosome by CRISPR in human cells

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  • In genomics: 1,139 out of 4,902
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A new massively parallel nanoball sequencing platform for whole exome research

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  • In genomics: 1,284 out of 4,902
• Year to date:
  • Site-wide: 10,746 out of 74,094
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  • Site-wide: 10,746 out of 74,094

PIRD: Pan immune repertoire database

• Downloaded 986 times
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  • In immunology: 158 out of 1,947
• Year to date:
  • Site-wide: 21,182 out of 74,094
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  • Site-wide: 21,182 out of 74,094

Recent origin of an XX/XY sex-determination system in the ancient plant lineage Ginkgo biloba

• Downloaded 985 times
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  • Site-wide: 9,019 out of 74,094
  • In evolutionary biology: 539 out of 4,780
• Year to date:
  • Site-wide: 10,599 out of 74,094
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  • Site-wide: 10,599 out of 74,094

Gene-centric intra- and inter-clade recombination in a context of Escherichia coli subpopulations

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  • In microbiology: 440 out of 6,053
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  • Site-wide: 23,060 out of 74,094
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  • Site-wide: 23,060 out of 74,094

A catalog of microbial genes from the bovine rumen unveils a specialized and diverse biomass-degrading environment

• Downloaded 921 times
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  • Site-wide: 10,040 out of 74,094
  • In microbiology: 451 out of 6,053
• Year to date:
  • Site-wide: 12,035 out of 74,094
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  • Site-wide: 12,035 out of 74,094

Life history recorded in the vagino-cervical microbiome

• Downloaded 874 times
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  • Site-wide: 10,916 out of 74,094
  • In microbiology: 501 out of 6,053
• Year to date:
  • Site-wide: 10,142 out of 74,094
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  • Site-wide: 10,142 out of 74,094

Small effect size leads to reproducibility failure in resting-state fMRI studies

• Downloaded 778 times
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  • Site-wide: 13,000 out of 74,094
  • In neuroscience: 2,131 out of 13,328
• Year to date:
  • Site-wide: 28,819 out of 74,094
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  • Site-wide: 28,819 out of 74,094

Fecal microbiota transplantation brings about bacterial strain displacement in patients with inflammatory bowel diseases

• Downloaded 763 times
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  • Site-wide: 13,387 out of 74,094
  • In clinical trials: 24 out of 99
• Year to date:
  • Site-wide: 14,670 out of 74,094
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  • Site-wide: 14,670 out of 74,094

Single-cell RNA-seq reveals distinct dynamic behavior of sex chromosomes during early human embryogenesis

• Downloaded 710 times
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  • Site-wide: 14,906 out of 74,094
  • In developmental biology: 344 out of 2,225
• Year to date:
  • Site-wide: 7,740 out of 74,094
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  • Site-wide: 7,740 out of 74,094

Integrated Analysis Revealed Hub Genes in Breast Cancer

• Downloaded 682 times
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  • Site-wide: 15,782 out of 74,094
  • In bioinformatics: 2,459 out of 7,201
• Year to date:
  • Site-wide: 32,120 out of 74,094
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  • Site-wide: 32,120 out of 74,094

Gene Panel Sequencing in a Chinese High-risk Breast Cancer Cohort

• Downloaded 680 times
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  • Site-wide: 15,858 out of 74,094
  • In cancer biology: 477 out of 2,540
• Year to date:
  • Site-wide: 19,862 out of 74,094
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  • Site-wide: 19,862 out of 74,094

The landscape of somatic mutation in sporadic Chinese colorectal cancer

• Downloaded 648 times
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  • Site-wide: 17,008 out of 74,094
  • In genomics: 2,112 out of 4,902
• Year to date:
  • Site-wide: 31,217 out of 74,094
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  • Site-wide: 31,217 out of 74,094

Integration of gut microbiome, host biomarkers, and urine metabolome data reveals networks of interactions associated with distinct clinical phenotypes

• Downloaded 626 times
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  • Site-wide: 17,879 out of 74,094
  • In microbiology: 930 out of 6,053
• Year to date:
  • Site-wide: 14,785 out of 74,094
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  • Site-wide: 14,785 out of 74,094

Age-dependent sexual dimorphism in the adult human gut microbiota

• Downloaded 608 times
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  • Site-wide: 18,666 out of 74,094
  • In genomics: 2,245 out of 4,902
• Year to date:
  • Site-wide: 57,332 out of 74,094
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  • Site-wide: 57,332 out of 74,094

Draft genome sequence of the Solanum aethiopicum provides insights into disease resistance, drought tolerance and the evolution of the genome

• Downloaded 588 times
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  • Site-wide: 19,548 out of 74,094
  • In genomics: 2,315 out of 4,902
• Year to date:
  • Site-wide: 43,565 out of 74,094
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  • Site-wide: 43,565 out of 74,094

Over 50000 metagenomically assembled draft genomes for the human oral microbiome reveal new taxa

• Downloaded 555 times
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  • Site-wide: 21,137 out of 74,094
  • In microbiology: 1,151 out of 6,053
• Year to date:
  • Site-wide: 12,753 out of 74,094
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  • Site-wide: 12,753 out of 74,094

Enhance genome editing efficiency and specificity by a quick CRISPR/Cas9 system

• Downloaded 539 times
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  • Site-wide: 21,966 out of 74,094
  • In genetics: 1,454 out of 4,058
• Year to date:
  • Site-wide: 14,056 out of 74,094
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  • Site-wide: 14,056 out of 74,094

The mitochondrial DNA content can not predict the embryo viability

• Downloaded 538 times
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  • Site-wide: 22,022 out of 74,094
  • In ecology: 641 out of 3,220
• Year to date:
  • Site-wide: 22,124 out of 74,094
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  • Site-wide: 22,124 out of 74,094

Identification of gut microbiome markers for schizophrenia delineates a potential role of Streptococcus

• Downloaded 515 times
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  • Site-wide: 23,321 out of 74,094
  • In microbiology: 1,286 out of 6,053
• Year to date:
  • Site-wide: 8,006 out of 74,094
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  • Site-wide: 8,006 out of 74,094

A chromosome-level genome of black rockfish, Sebastes schlegelii, provides insights into the evolution of live birth

• Downloaded 514 times
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  • In genomics: 2,590 out of 4,902
• Year to date:
  • Site-wide: 21,294 out of 74,094
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  • Site-wide: 21,294 out of 74,094

Base editing in Streptomyces with Cas9-deaminase fusions

• Downloaded 492 times
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  • In microbiology: 1,390 out of 6,053
• Year to date:
  • Site-wide: 3,620 out of 74,094
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  • Site-wide: 3,620 out of 74,094

Identification of Variable and Joining germline genes and alleles for Rhesus macaque from B-cell receptor repertoires

• Downloaded 469 times
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  • Site-wide: 26,145 out of 74,094
  • In immunology: 534 out of 1,947
• Year to date:
  • Site-wide: 40,691 out of 74,094
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  • Site-wide: 40,691 out of 74,094

Calorie restriction intervention induces enterotype-associated BMI loss in nonobese individuals

• Downloaded 408 times
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  • Site-wide: 30,726 out of 74,094
  • In microbiology: 1,860 out of 6,053
• Year to date:
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  • Site-wide: 30,452 out of 74,094

Dynamic chromosome rearrangements of the white-spotted bamboo shark shed light on cartilaginous fish diversification mechanisms

• Downloaded 372 times
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  • Site-wide: 33,872 out of 74,094
  • In genomics: 3,275 out of 4,902
• Year to date:
  • Site-wide: 11,511 out of 74,094
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  • Site-wide: 11,511 out of 74,094

TCR repertoire analysis reveals effector memory T cells differentiation into Th17 cells in rheumatoid arthritis

• Downloaded 363 times
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  • Site-wide: 34,774 out of 74,094
  • In immunology: 741 out of 1,947
• Year to date:
  • Site-wide: 21,644 out of 74,094
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  • Site-wide: 21,644 out of 74,094

PALM-Seq: simultaneous sequencing of cell-free long RNA and small RNA

• Downloaded 348 times
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  • Site-wide: 36,331 out of 74,094
  • In molecular biology: 1,093 out of 2,415
• Year to date:
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  • Site-wide: 15,977 out of 74,094

Nationwide population genetic screening improves outcomes of newborn screening for hearing loss in China

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  • In genetics: 2,261 out of 4,058
• Year to date:
  • Site-wide: 25,994 out of 74,094
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  • Site-wide: 25,994 out of 74,094

Engineering of Chimeric Antigen Receptor T Cells with integrin αEβ7 Results in Augmented Therapeutic Efficacy against E-cadherin positive tumor

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  • Site-wide: 42,274 out of 74,094
  • In immunology: 944 out of 1,947
• Year to date:
  • Site-wide: 12,937 out of 74,094
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  • Site-wide: 12,937 out of 74,094

Distinct gut metagenomics and metaproteomics signatures in prediabetics and treatment-naïve type 2 diabetics

• Downloaded 264 times
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  • Site-wide: 45,980 out of 74,094
  • In microbiology: 3,156 out of 6,053
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  • Site-wide: 35,247 out of 74,094
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Sequencing of the MHC region defines HLA-DQA1 as the major independent risk for anti-citrullinated protein antibodies (ACPA)-positive rheumatoid arthritis in Han population

• Downloaded 255 times
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  • Site-wide: 47,306 out of 74,094
  • In genetics: 2,813 out of 4,058
• Year to date:
  • Site-wide: 40,466 out of 74,094
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  • Site-wide: 40,466 out of 74,094

Detection of Ovarian Cancer Using Cells Sourced from a Local Microenvironment

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  • Site-wide: 47,200 out of 74,094
  • In cancer biology: 1,516 out of 2,540
• Year to date:
  • Site-wide: 62,929 out of 74,094
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  • Site-wide: 62,929 out of 74,094

M-GWAS for the gut microbiome in Chinese adults illuminates on complex diseases

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  • In genetics: 2,956 out of 4,058
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  • Site-wide: 18,243 out of 74,094
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  • Site-wide: 18,243 out of 74,094

Spreading predictability in complex networks

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  • Site-wide: 51,302 out of 74,094
  • In bioinformatics: 5,674 out of 7,201
• Year to date:
  • Site-wide: 1,669 out of 74,094
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  • Site-wide: 1,669 out of 74,094

New genetic variants associated with major adverse cardiovascular events in patients with acute coronary syndromes and treated with clopidogrel and aspirin

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  • In genetics: 3,054 out of 4,058
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The landscape and diagnostic potential of T and B cell repertoire in Immunoglobulin A Nephropathy

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  • In immunology: 1,216 out of 1,947
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  • Site-wide: 42,096 out of 74,094

The Urinary Microbiota in Relation to the Reproductive Tract Microbiota

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  • In microbiology: 3,813 out of 6,053
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Tau Accumulation via Reduced BAG3-mediated Autophagy Is Required for GGGGCC Repeat Expansion-Induced Neurodegeneration

• Downloaded 178 times
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  • Site-wide: 58,697 out of 74,094
  • In neuroscience: 10,500 out of 13,328
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  • Site-wide: 43,043 out of 74,094
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  • Site-wide: 43,043 out of 74,094

SOAPTyping: an open-source and cross-platform tool for Sanger sequence-based typing for HLA class I and II alleles

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  • Site-wide: 60,569 out of 74,094
  • In bioinformatics: 6,349 out of 7,201
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WinnerTakeAlmostAll: A parsimony approach integrating multi-targets improves marker gene profiling

• Downloaded 162 times
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  • In bioinformatics: 6,390 out of 7,201
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  • Site-wide: 60,927 out of 74,094

Integrative framework of cross-module deep biomarker for the prognosis of clear cell renal cell carcinoma: A retrospective TCGA project

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  • In bioinformatics: 6,574 out of 7,201
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  • Site-wide: 34,834 out of 74,094

TET1-mediated Oligodendrocyte Homeostasis Regulates Myelination and Synaptic Functions

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  • In neuroscience: 11,469 out of 13,328
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  • Site-wide: 28,303 out of 74,094

Expression, Purification, and Functional Reconstitution of 19F-labeled Cytochrome b5 in Peptide Nanodiscs for NMR Studies

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  • Site-wide: 68,829 out of 74,094
  • In biochemistry: 2,054 out of 2,264
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Cdc42 is required for lymphatic branching, maturation and valve formation during embryonic development

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  • Site-wide: 70,671 out of 74,094
  • In developmental biology: 2,141 out of 2,225
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  • Site-wide: 7,226 out of 74,094

Fibroblast growth factor-2 prevents synaptic pathology in minimal hepatic encephalopathy via NRG1/ErbB4 signaling

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  • In neuroscience: 12,887 out of 13,328
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  • Site-wide: 49,969 out of 74,094

The inverse relationship between fibronectin and neuroligins in the embryonic rat colon

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  • In cell biology: 3,535 out of 3,655
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Various miRNAs are involved in efficient HCV replication

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Src/FAK complex phosphorylates cardiac myosin binding protein c (cMyBP-C) in vitro and in vivo

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  • In molecular biology: 2,334 out of 2,415
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