Rxivist combines preprints from bioRxiv with data from Twitter to help you find the papers being discussed in your field. Currently indexing 60,222 bioRxiv papers from 267,721 authors.

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Preprints

Efficient long single molecule sequencing for cost effective and accurate sequencing, haplotyping, and de novo assembly

• Downloaded 4,618 times
• Download rankings, all-time:
  • Site-wide: 446 out of 60,222
  • In genomics: 120 out of 4,168
• Year to date:
  • Site-wide: 232 out of 60,222
• Since beginning of last month:
  • Site-wide: 1,205 out of 60,222

Rapid Automated Large Structural Variation Detection in a Diploid Genome by NanoChannel Based Next-Generation Mapping

• Downloaded 1,601 times
• Download rankings, all-time:
  • Site-wide: 3,130 out of 60,222
  • In genomics: 607 out of 4,168
• Year to date:
  • Site-wide: 19,530 out of 60,222
• Since beginning of last month:
  • Site-wide: 20,101 out of 60,222

Reliable Multiplex Sequencing with Rare Index Mis-Assignment on DNB-Based NGS Platform

• Downloaded 1,341 times
• Download rankings, all-time:
  • Site-wide: 4,215 out of 60,222
  • In genomics: 770 out of 4,168
• Year to date:
  • Site-wide: 3,826 out of 60,222
• Since beginning of last month:
  • Site-wide: 14,058 out of 60,222

Single-cell Transcriptomic Landscape of Nucleated Cells in Umbilical Cord Blood

• Downloaded 1,297 times
• Download rankings, all-time:
  • Site-wide: 4,463 out of 60,222
  • In genomics: 806 out of 4,168
• Year to date:
  • Site-wide: 2,913 out of 60,222
• Since beginning of last month:
  • Site-wide: 5,042 out of 60,222

Circularization of genes and chromosome by CRISPR in human cells

• Downloaded 1,073 times
• Download rankings, all-time:
  • Site-wide: 6,099 out of 60,222
  • In genomics: 1,018 out of 4,168
• Year to date:
  • Site-wide: 20,418 out of 60,222
• Since beginning of last month:
  • Site-wide: 36,478 out of 60,222

A multi-omic cohort as a reference point for promoting a healthy human gut microbiome

• Downloaded 957 times
• Download rankings, all-time:
  • Site-wide: 7,297 out of 60,222
  • In microbiology: 301 out of 4,799
• Year to date:
  • Site-wide: 1,395 out of 60,222
• Since beginning of last month:
  • Site-wide: 2,782 out of 60,222

PIRD: Pan immune repertoire database

• Downloaded 846 times
• Download rankings, all-time:
  • Site-wide: 8,882 out of 60,222
  • In immunology: 137 out of 1,466
• Year to date:
  • Site-wide: 4,836 out of 60,222
• Since beginning of last month:
  • Site-wide: 2,706 out of 60,222

Gene-centric intra- and inter-clade recombination in a context of Escherichia coli subpopulations

• Downloaded 837 times
• Download rankings, all-time:
  • Site-wide: 9,037 out of 60,222
  • In microbiology: 390 out of 4,799
• Year to date:
  • Site-wide: 18,631 out of 60,222
• Since beginning of last month:
  • Site-wide: 22,548 out of 60,222

Recent origin of an XX/XY sex-determination system in the ancient plant lineage Ginkgo biloba

• Downloaded 810 times
• Download rankings, all-time:
  • Site-wide: 9,496 out of 60,222
  • In evolutionary biology: 638 out of 4,111
• Year to date:
  • Site-wide: 1,866 out of 60,222
• Since beginning of last month:
  • Site-wide: 7,242 out of 60,222

A new massively parallel nanoball sequencing platform for whole exome research

• Downloaded 799 times
• Download rankings, all-time:
  • Site-wide: 9,672 out of 60,222
  • In genomics: 1,443 out of 4,168
• Year to date:
  • Site-wide: 2,709 out of 60,222
• Since beginning of last month:
  • Site-wide: 4,508 out of 60,222

A catalog of microbial genes from the bovine rumen unveils a specialized and diverse biomass-degrading environment

• Downloaded 758 times
• Download rankings, all-time:
  • Site-wide: 10,462 out of 60,222
  • In microbiology: 471 out of 4,799
• Year to date:
  • Site-wide: 12,926 out of 60,222
• Since beginning of last month:
  • Site-wide: 13,493 out of 60,222

Small effect size leads to reproducibility failure in resting-state fMRI studies

• Downloaded 684 times
• Download rankings, all-time:
  • Site-wide: 12,122 out of 60,222
  • In neuroscience: 1,943 out of 10,621
• Year to date:
  • Site-wide: 20,638 out of 60,222
• Since beginning of last month:
  • Site-wide: 22,644 out of 60,222

Life history recorded in the vagino-cervical microbiome

• Downloaded 676 times
• Download rankings, all-time:
  • Site-wide: 12,316 out of 60,222
  • In microbiology: 580 out of 4,799
• Year to date:
  • Site-wide: 2,564 out of 60,222
• Since beginning of last month:
  • Site-wide: 2,641 out of 60,222

A Single-Cell Immune Atlas of Triple Negative Breast Cancer Reveals Novel Immune Cell Subsets

• Downloaded 635 times
• Download rankings, all-time:
  • Site-wide: 13,436 out of 60,222
  • In immunology: 224 out of 1,466
• Year to date:
  • Site-wide: 2,862 out of 60,222
• Since beginning of last month:
  • Site-wide: 1,503 out of 60,222

Fecal microbiota transplantation brings about bacterial strain displacement in patients with inflammatory bowel diseases

• Downloaded 574 times
• Download rankings, all-time:
  • Site-wide: 15,435 out of 60,222
  • In clinical trials: 23 out of 99
• Year to date:
  • Site-wide: 5,427 out of 60,222
• Since beginning of last month:
  • Site-wide: 3,855 out of 60,222

The landscape of somatic mutation in sporadic Chinese colorectal cancer

• Downloaded 572 times
• Download rankings, all-time:
  • Site-wide: 15,508 out of 60,222
  • In genomics: 1,973 out of 4,168
• Year to date:
  • Site-wide: 34,053 out of 60,222
• Since beginning of last month:
  • Site-wide: 35,525 out of 60,222

Integrated Analysis Revealed Hub Genes in Breast Cancer

• Downloaded 569 times
• Download rankings, all-time:
  • Site-wide: 15,585 out of 60,222
  • In bioinformatics: 2,452 out of 6,078
• Year to date:
  • Site-wide: 9,066 out of 60,222
• Since beginning of last month:
  • Site-wide: 9,840 out of 60,222

Age-dependent sexual dimorphism in the adult human gut microbiota

• Downloaded 546 times
• Download rankings, all-time:
  • Site-wide: 16,480 out of 60,222
  • In genomics: 2,067 out of 4,168
• Year to date:
  • Site-wide: 3,717 out of 60,222
• Since beginning of last month:
  • Site-wide: 23,439 out of 60,222

Draft genome sequence of the Solanum aethiopicum provides insights into disease resistance, drought tolerance and the evolution of the genome

• Downloaded 498 times
• Download rankings, all-time:
  • Site-wide: 18,465 out of 60,222
  • In genomics: 2,207 out of 4,168
• Year to date:
  • Site-wide: 4,302 out of 60,222
• Since beginning of last month:
  • Site-wide: 5,950 out of 60,222

Integration of gut microbiome, host biomarkers, and urine metabolome data reveals networks of interactions associated with distinct clinical phenotypes

• Downloaded 473 times
• Download rankings, all-time:
  • Site-wide: 19,682 out of 60,222
  • In microbiology: 1,047 out of 4,799
• Year to date:
  • Site-wide: 4,686 out of 60,222
• Since beginning of last month:
  • Site-wide: 14,518 out of 60,222

Gene Panel Sequencing in a Chinese High-risk Breast Cancer Cohort

• Downloaded 473 times
• Download rankings, all-time:
  • Site-wide: 19,656 out of 60,222
  • In cancer biology: 589 out of 1,975
• Year to date:
  • Site-wide: 4,680 out of 60,222
• Since beginning of last month:
  • Site-wide: 4,494 out of 60,222

Single-cell RNA-seq reveals distinct dynamic behavior of sex chromosomes during early human embryogenesis

• Downloaded 454 times
• Download rankings, all-time:
  • Site-wide: 20,652 out of 60,222
  • In developmental biology: 528 out of 1,790
• Year to date:
  • Site-wide: 10,073 out of 60,222
• Since beginning of last month:
  • Site-wide: 16,911 out of 60,222

The mitochondrial DNA content can not predict the embryo viability

• Downloaded 431 times
• Download rankings, all-time:
  • Site-wide: 21,912 out of 60,222
  • In ecology: 674 out of 2,558
• Year to date:
  • Site-wide: 6,904 out of 60,222
• Since beginning of last month:
  • Site-wide: 6,312 out of 60,222

A chromosome-level genome of black rockfish, Sebastes schlegelii, provides insights into the evolution of live birth

• Downloaded 423 times
• Download rankings, all-time:
  • Site-wide: 22,350 out of 60,222
  • In genomics: 2,482 out of 4,168
• Year to date:
  • Site-wide: 5,652 out of 60,222
• Since beginning of last month:
  • Site-wide: 17,884 out of 60,222

Identification of Variable and Joining germline genes and alleles for Rhesus macaque from B-cell receptor repertoires

• Downloaded 396 times
• Download rankings, all-time:
  • Site-wide: 24,037 out of 60,222
  • In immunology: 429 out of 1,466
• Year to date:
  • Site-wide: 30,596 out of 60,222
• Since beginning of last month:
  • Site-wide: 29,936 out of 60,222

Enhance genome editing efficiency and specificity by a quick CRISPR/Cas9 system

• Downloaded 336 times
• Download rankings, all-time:
  • Site-wide: 28,388 out of 60,222
  • In genetics: 1,837 out of 3,432
• Year to date:
  • Site-wide: 8,251 out of 60,222
• Since beginning of last month:
  • Site-wide: 481 out of 60,222

Calorie restriction intervention induces enterotype-associated BMI loss in nonobese individuals

• Downloaded 267 times
• Download rankings, all-time:
  • Site-wide: 34,749 out of 60,222
  • In microbiology: 2,228 out of 4,799
• Year to date:
  • Site-wide: 11,907 out of 60,222
• Since beginning of last month:
  • Site-wide: 13,991 out of 60,222

Base editing in Streptomyces with Cas9-deaminase fusions

• Downloaded 262 times
• Download rankings, all-time:
  • Site-wide: 35,189 out of 60,222
  • In microbiology: 2,280 out of 4,799
• Year to date:
  • Site-wide: 12,232 out of 60,222
• Since beginning of last month:
  • Site-wide: 8,148 out of 60,222

TCR repertoire analysis reveals effector memory T cells differentiation into Th17 cells in rheumatoid arthritis

• Downloaded 254 times
• Download rankings, all-time:
  • Site-wide: 36,101 out of 60,222
  • In immunology: 710 out of 1,466
• Year to date:
  • Site-wide: 12,806 out of 60,222
• Since beginning of last month:
  • Site-wide: 19,894 out of 60,222

Nationwide population genetic screening improves outcomes of newborn screening for hearing loss in China

• Downloaded 237 times
• Download rankings, all-time:
  • Site-wide: 37,920 out of 60,222
  • In genetics: 2,351 out of 3,432
• Year to date:
  • Site-wide: 19,720 out of 60,222
• Since beginning of last month:
  • Site-wide: 30,500 out of 60,222

Dynamic chromosome rearrangements of the white-spotted bamboo shark shed light on cartilaginous fish diversification mechanisms

• Downloaded 227 times
• Download rankings, all-time:
  • Site-wide: 39,027 out of 60,222
  • In genomics: 3,406 out of 4,168
• Year to date:
  • Site-wide: 15,015 out of 60,222
• Since beginning of last month:
  • Site-wide: 32,645 out of 60,222

Sequencing of the MHC region defines HLA-DQA1 as the major independent risk for anti-citrullinated protein antibodies (ACPA)-positive rheumatoid arthritis in Han population

• Downloaded 210 times
• Download rankings, all-time:
  • Site-wide: 41,090 out of 60,222
  • In genetics: 2,501 out of 3,432
• Year to date:
  • Site-wide: 29,119 out of 60,222
• Since beginning of last month:
  • Site-wide: 42,779 out of 60,222

Detection of Ovarian Cancer Using Cells Sourced from a Local Microenvironment

• Downloaded 206 times
• Download rankings, all-time:
  • Site-wide: 41,516 out of 60,222
  • In cancer biology: 1,294 out of 1,975
• Year to date:
  • Site-wide: 17,018 out of 60,222
• Since beginning of last month:
  • Site-wide: 22,569 out of 60,222

Distinct gut metagenomics and metaproteomics signatures in prediabetics and treatment-naïve type 2 diabetics

• Downloaded 189 times
• Download rankings, all-time:
  • Site-wide: 43,557 out of 60,222
  • In microbiology: 2,997 out of 4,799
• Year to date:
  • Site-wide: 19,053 out of 60,222
• Since beginning of last month:
  • Site-wide: 14,805 out of 60,222

PALM-Seq: simultaneous sequencing of cell-free long RNA and small RNA

• Downloaded 180 times
• Download rankings, all-time:
  • Site-wide: 44,683 out of 60,222
  • In molecular biology: 1,304 out of 1,850
• Year to date:
  • Site-wide: 20,275 out of 60,222
• Since beginning of last month:
  • Site-wide: 11,019 out of 60,222

New genetic variants associated with major adverse cardiovascular events in patients with acute coronary syndromes and treated with clopidogrel and aspirin

• Downloaded 177 times
• Download rankings, all-time:
  • Site-wide: 45,089 out of 60,222
  • In genetics: 2,734 out of 3,432
• Year to date:
  • Site-wide: 43,806 out of 60,222
• Since beginning of last month:
  • Site-wide: 35,904 out of 60,222

The landscape and diagnostic potential of T and B cell repertoire in Immunoglobulin A Nephropathy

• Downloaded 171 times
• Download rankings, all-time:
  • Site-wide: 45,815 out of 60,222
  • In immunology: 990 out of 1,466
• Year to date:
  • Site-wide: 52,132 out of 60,222
• Since beginning of last month:
  • Site-wide: 24,047 out of 60,222

The Urinary Microbiota in Relation to the Reproductive Tract Microbiota

• Downloaded 125 times
• Download rankings, all-time:
  • Site-wide: 51,881 out of 60,222
  • In microbiology: 3,834 out of 4,799
• Year to date:
  • Site-wide: 30,220 out of 60,222
• Since beginning of last month:
  • Site-wide: 24,521 out of 60,222

WinnerTakeAlmostAll: A parsimony approach integrating multi-targets improves marker gene profiling

• Downloaded 125 times
• Download rankings, all-time:
  • Site-wide: 51,873 out of 60,222
  • In bioinformatics: 5,589 out of 6,078
• Year to date:
  • Site-wide: 30,023 out of 60,222
• Since beginning of last month:
  • Site-wide: 47,325 out of 60,222

Tau Accumulation via Reduced BAG3-mediated Autophagy Is Required for GGGGCC Repeat Expansion-Induced Neurodegeneration

• Downloaded 114 times
• Download rankings, all-time:
  • Site-wide: 53,247 out of 60,222
  • In neuroscience: 9,357 out of 10,621
• Year to date:
  • Site-wide: 32,603 out of 60,222
• Since beginning of last month:
  • Site-wide: 3,022 out of 60,222

Engineering of Chimeric Antigen Receptor T Cells with integrin αEβ7 Results in Augmented Therapeutic Efficacy against E-cadherin positive tumor

• Downloaded 113 times
• Download rankings, all-time:
  • Site-wide: 53,352 out of 60,222
  • In immunology: 1,245 out of 1,466
• Year to date:
  • Site-wide: 32,989 out of 60,222
• Since beginning of last month:
  • Site-wide: 3,065 out of 60,222

M-GWAS for the gut microbiome in Chinese adults illuminates on complex diseases

• Downloaded 107 times
• Download rankings, all-time:
  • Site-wide: 54,147 out of 60,222
  • In genetics: 3,153 out of 3,432
• Year to date:
  • Site-wide: 34,500 out of 60,222
• Since beginning of last month:
  • Site-wide: 3,371 out of 60,222

Integrative framework of cross-module deep biomarker for the prognosis of clear cell renal cell carcinoma: A retrospective TCGA project

• Downloaded 67 times
• Download rankings, all-time:
  • Site-wide: 57,717 out of 60,222
  • In bioinformatics: 5,914 out of 6,078
• Year to date:
  • Site-wide: 47,737 out of 60,222
• Since beginning of last month:
  • Site-wide: 6,695 out of 60,222

SOAPTyping: an open-source and cross-platform tool for Sanger sequence-based typing for HLA class I and II alleles

• Downloaded 65 times
• Download rankings, all-time:
  • Site-wide: 57,820 out of 60,222
  • In bioinformatics: 5,921 out of 6,078
• Year to date:
  • Site-wide: 48,710 out of 60,222
• Since beginning of last month:
  • Site-wide: 28,083 out of 60,222

The inverse relationship between fibronectin and neuroligins in the embryonic rat colon

• Downloaded 40 times
• Download rankings, all-time:
  • Site-wide: 58,784 out of 60,222
  • In cell biology: 2,790 out of 2,865
• Year to date:
  • Site-wide: 57,394 out of 60,222
• Since beginning of last month:
  • Site-wide: 12,570 out of 60,222