Author: Wei Li

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Preprints

Identification of transcription factors involved in the specification of photoreceptor subtypes

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Cold protection allows local cryotherapy in a clinical-relevant model of traumatic optic neuropathy

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Bioconda: A sustainable and comprehensive software distribution for the life sciences

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  • Site-wide: 1,930
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  • Site-wide: 9,438
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  • Site-wide: 13,864

Rapid selection of a human monoclonal antibody that potently neutralizes SARS-CoV-2 in two animal models

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  • Site-wide: 4,605
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  • Site-wide: 34,252

Detecting Tumor Specific Antigen-Reactive T cells from Tumor Infiltrating Lymphocytes via Interaction Dependent Fucosyl-biotinylation

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  • Site-wide: 5,572
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Multi-omics analysis of chromatin accessibility and interactions with transcriptome by HiCAR

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  • Site-wide: 6,027

A Cell Type-Specific Class of Chromatin Loops Anchored at Large DNA Methylation Nadirs

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SARS-CoV-2 detection with CRISPR diagnostics

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  • Site-wide: 9,091
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Click-ExM enables expansion microscopy for all biomolecules

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  • Site-wide: 9,234
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  • Site-wide: 25,155

Reducing False Positives in CRISPR/Cas9 Screens from Copy Number Variations

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A new method for rapid genome classification, clustering, visualization, and novel taxa discovery from metagenome

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  • Site-wide: 10,034
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  • Site-wide: 39,093

Identification of novel rare sequence variation underlying heritable pulmonary arterial hypertension

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  • Site-wide: 13,590
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  • Site-wide: 80,586
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  • Site-wide: 106,861

Metagenomic Next-generation Sequencing of Cerebrospinal Fluid for the Diagnosis of Central Nervous System Infections: A Multicentre Prospective Study

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  • Site-wide: 15,156
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  • Site-wide: 63,087

Linking genotypes with multiple phenotypes in single-cell CRISPR screens

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  • Site-wide: 15,331
  • In bioinformatics: 1,731
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  • Site-wide: 106,180
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  • Site-wide: 70,579

Diversification of molecularly defined myenteric neuron classes revealed by single cell RNA-sequencing

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  • Site-wide: 18,299
  • In neuroscience: 2,150
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  • Site-wide: 98,582

Clipper: p-value-free FDR control on high-throughput data from two conditions

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  • Site-wide: 19,674
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Genetic Basis of Alternative Polyadenylation is an Emerging Molecular Phenotype for Human Traits and Diseases

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  • Site-wide: 21,415
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Exploring functional variation affecting ceRNA regulation in humans

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  • Site-wide: 22,289
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SMRT sequencing yields the chromosome-scale reference genome of tea tree, Camellia sinensis var. sinensis

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  • Site-wide: 23,188
  • In genomics: 2,149
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  • Site-wide: 103,544

Integrative analysis and refined design of CRISPR knockout screens

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  • Site-wide: 23,226
  • In bioinformatics: 2,610
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  • Site-wide: 88,149
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  • Site-wide: 127,322

Single cell RNA-seq reveals cellular diversity and developmental characteristics of human infant retina

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  • Site-wide: 23,732
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  • Site-wide: 106,739

Potential microenvironment of SARS-CoV-2 infection in airway epithelial cells revealed by Human Protein Atlas database analysis

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  • Site-wide: 26,674
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  • Site-wide: 75,244
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  • Site-wide: 114,776

Biophysical properties of AKAP95 protein condensates regulate splicing and tumorigenesis

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  • Site-wide: 28,124
  • In biochemistry: 639
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  • Site-wide: 68,008
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  • Site-wide: 28,616

Radial contractility of Actomyosin-II rings facilitates cargo trafficking and maintains axonal structural stability following cargo-induced transient axonal expansion

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  • Site-wide: 28,212
  • In neuroscience: 3,547
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  • Site-wide: 76,486
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  • Site-wide: 78,691

Poly(A)-ClickSeq: click-chemistry for next-generation 3′-end sequencing without RNA enrichment or fragmentation

• Downloaded 943 times
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  • Site-wide: 31,033
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CRISPR/Cas9 screens Reveal Dasatinib Targets of Inhibiting T cell Activation and Proliferation

• Downloaded 938 times
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  • Site-wide: 31,307
  • In cancer biology: 812
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  • Site-wide: 66,933

SMRT sequencing generates the chromosome-scale reference genome of tropical fruit mango, Mangifera indica

• Downloaded 926 times
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  • Site-wide: 31,895
  • In genomics: 2,712
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  • Site-wide: 46,023
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  • Site-wide: 60,762

GCNA preserves genome integrity and fertility across species

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  • Site-wide: 37,352
  • In developmental biology: 760
• Year to date:
  • Site-wide: 130,291
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  • Site-wide: 149,647

Dual functions of Intraflagellar Transport Protein IFT20 in spermiogenesis: formation of sperm flagella and removal of cytoplasm by autophagy

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  • Site-wide: 37,765
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  • Site-wide: 134,346
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  • Site-wide: 116,401

The histone modification reader ZCWPW1 links histone methylation to PRDM9-induced double strand break repair

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  • Site-wide: 43,336
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  • Site-wide: 78,100
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  • Site-wide: 39,042

Single cell RNA sequencing reveals cellular diversity of trisomy 21 retina

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  • Site-wide: 43,628
  • In cell biology: 1,768
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  • Site-wide: 99,344
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  • Site-wide: 91,843

m6A Regulates Liver Metabolic Disorders and Hepatogenous Diabetes

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  • Site-wide: 45,331
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  • Site-wide: 66,992
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  • Site-wide: 50,634

Progressive lengthening of 3′ untranslated regions of mRNAs by alternative cleavage and polyadenylation in cellular senescence of mouse embryonic fibroblasts

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  • Site-wide: 47,748
  • In genomics: 3,670
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  • Site-wide: 114,644
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  • Site-wide: 112,315

Single cell atlas of trisomy 21 cerebral cortex

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  • Site-wide: 49,992
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  • Site-wide: 55,516
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  • Site-wide: 61,570

Immunity-and-Matrix-Regulatory Cells Derived from Human Embryonic Stem Cells Safely and Effectively Treat Mouse Lung Injury and Fibrosis

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  • Site-wide: 50,155
  • In cell biology: 2,118
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  • Site-wide: 131,932

Extensive alternative splicing transitions during postnatal skeletal muscle development are required for Ca2+ handling

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  • Site-wide: 53,147
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  • Site-wide: 111,395
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  • Site-wide: 78,447

Coordinate Enhancer Reprogramming by GATA3 and AP1 Promotes Phenotypic Plasticity to Achieve Breast Cancer Endocrine Resistance

• Downloaded 597 times
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  • Site-wide: 58,984
  • In cancer biology: 1,700
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  • Site-wide: 31,479

Diagnostic Whole Exome Sequencing in Patients with Short Stature

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  • Site-wide: 60,093
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  • Site-wide: 113,339
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Differences in GluN2B-containing NMDA receptors result in opposite long-term plasticity and dopaminergic modulation at ipsilateral vs. contralateral cortico-striatal synapses

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  • Site-wide: 60,904
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  • Site-wide: 106,821

Pre-implantation genetic diagnosis for a family with Usher syndrome through targeted sequencing and haplotype analysis

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  • Site-wide: 61,989
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HiAlc Klebsiella pneumonia, one of potential chief culprits of non-alcoholic fatty liver disease: through generation of endogenous ethanol

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  • Site-wide: 68,489
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  • Site-wide: 112,961

Cyclin B3 is specifically required for metaphase to anaphase transition in mouse oocyte meiosis I

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  • Site-wide: 70,131
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  • Site-wide: 106,254

Global lengthening of 3′ untranslated regions of mRNAs by alternative cleavage and polyadenylation in cellular senescence

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  • Site-wide: 70,190
  • In genomics: 4,844
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  • Site-wide: 95,915

Long Non-Coding RNA LncKdm2b Regulates Cortical Neuronal Differentiation by Cis-Activating Kdm2b

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  • Site-wide: 73,025
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Long-Term Potentiation Induces Extrasynaptic Exocytosis of Glun2A-containing NMDA Receptors that is Mainly Controlled by SNAP23

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Circulating BMP9 protects the pulmonary endothelium during inflammation-induced lung injury in mice

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  • Site-wide: 77,115
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Essential role of Bone morphogenetic protein 15 in porcine ovarian and follicular development and ovulation

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Rapid Detection of Burkholderia pseudomallei with a Lateral Flow Recombinase Polymerase Amplification Assay

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SMRT sequencing of the Oryza rufipogon genome reveals the genomic basis of rice adaptation

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SLFL Genes Participate in the Ubiquitination and Degradation of S-RNase in Self-Compatible Chinese Peach

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Deciphering tea tree chloroplast and mitochondrial genomes of Camellia sinensis var. assamica

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  • Site-wide: 86,457
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Structural variability and functional association in the epiphytic bacteria assemblies of freshwater macrophytes (Myriophyllum spicatum)

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Effect of arbuscular mycorrhizal fungi (AMF) and plant growth promoting rhizobacteria (PGPR) on microbial community structure of phenanthrene and pyrene contaminated soils using Illumina HiSeq sequencing.

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  • Site-wide: 88,552
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  • Site-wide: 98,350

Modeling CRISPR-Cas13d on-target and off-target effects using machine learning approaches

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  • Site-wide: 17,319

True S-cones are concentrated in the ventral mouse retina for color detection in the upper visual field

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  • Site-wide: 90,433
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Cooperation-based sperm clusters mediate sperm oviduct entry and fertilization

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Numerical Investigation of Drug Transport from Blood Vessels to Tumor Tissue Using a Tumor-Vasculature-on-a-Chip

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Temporal regulation of prenatal embryonic development by paternal imprinted loci

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Noninvasive prenatal test of methylmalonic academia cblC type through targeted sequencing of cell-free DNA in maternal plasma

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  • Site-wide: 95,359
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A large-sample crisis? Exaggerated false positives by popular differential expression methods

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Hsa_circ_0001947 suppresses acute myeloid leukemia progression by sponging hsa-miR-329-5p and regulating CREBRF expression

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Cellular heterogeneity-adjusted clonal methylation (CHALM) provides better prediction of gene expression

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BLOS1 mediates kinesin switch during endosomal recycling of LDL receptor

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Clinical diagnosis of single-gene disorders and chromosomal abnormalities based on BGISEQ-500 platform

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Lactate Increases Stemness of CD8+ T Cells to Augment Anti-Tumor Immunity

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ATM and ATR Influence Meiotic Crossover Formation Through Antagonistic and Overlapping Functions in C. elegans

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Identification of TTN as a novel candidate gene for atrioventricular block in a Chinese pedigree by whole-exome sequencing

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Targeting against HIV/HCV Co-infection using Machine Learning-based multitarget-quantitative structure-activity relationships (mt-QSAR) Methods

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A Reference Feature based method for Quantification and Identification of LC-MS based untargeted metabolomics

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Spectrin-based Membrane Mechanics Is Asymmetric and Remodels during Neural Development

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Influence of isolation by environment and landscape heterogeneity on genetic structure of wild rice Zizania latifolia along a latitudinal gradient

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The draft genome sequence of herbaceous diploid bamboo Raddia distichophylla

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DORGE: Discovery of Oncogenes and Tumor SuppressoR Genes Using Genetic and Epigenetic Features

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Intra-protein binding peptide fragments have specific and intrinsic sequence patterns

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Enabling in vivo Analysis Via Nanoparticle-mediated Intracellular Assay Probe Delivery: Using RAS as the Prototype

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Combinatorial phosphorylation modulates the structure and function of the G protein gamma subunit in yeast

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The key miRNAs for metastasis and survival of colon adenocarcinoma

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Whole-genome-based Helicobacter pylori geographic surveillance: a visualized and expandable webtool

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Impact of ultrasonography on identifying noninvasive prenatal screening false-negative aneuploidy

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Novel Vβ specific germline contacts shape an elite controller T cell response

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Decoding herbal materials of representative TCM preparations with the multi-barcoding approach

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Comparative analyses and phylogenetic relationships of 15 Trapa (Trapaceae) species based on Complete Chloroplast Genomes

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Integrated Regulation of PKA by Fast and Slow Neurotransmission in the Nucleus Accumbens Controls Plasticity and Stress Responses

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LRP-1 Commands Two Parallel Signalling Mechanisms to Support Constitutive Tumour Cell Motility in the Absence of Blood Supply

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