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Author: Gib Hemani

  • ORCiD: http://orcid.org/0000-0003-0920-1055
  • Most recently observed institution: MRC Integrative Epidemiology Unit (IEU), Population Health Sciences, University of Bristol, Bristol, United Kingdom.

Rankings

  • All-time downloads: 89,492 (rank: 1,613 )
  • Categories:
    • bioinformatics: 10,897 (rank: 776 )
    • epidemiology: 28,565 (rank: 584 )
    • evolutionary biology: 441 (rank: 16,029 (tie) )
    • genetic and genomic medicine: 970 (rank: 3,574 (tie) )
    • genetics: 31,170 (rank: 203 )
    • genomics: 13,293 (rank: 1,407 )
    • health policy: 950 (rank: 513 (tie) )
    • infectious diseases: 1,618 (rank: 19,652 (tie) )
    • neuroscience: 523 (rank: 46,812 (tie) )
    • psychiatry and clinical psychology: 71 (rank: 6,973 (tie) )
    • public and global health: 324 (rank: 8,771 (tie) )
    • systems biology: 670 (rank: 7,016 (tie) )

Downloads per author, site-wide

Preprints

Collider bias undermines our understanding of COVID-19 disease risk and severity

epidemiology more details view paper
  • Downloaded 12,488 times
  • Download rankings, all-time:
    • Site-wide: 708
    • In epidemiology: 101
  • Year to date:
    • Site-wide: 2,765
  • Since beginning of last month:
    • Site-wide: 3,165

Unraveling the polygenic architecture of complex traits using blood eQTL meta-analysis

genomics more details view paper
  • Downloaded 11,087 times
  • Download rankings, all-time:
    • Site-wide: 829
    • In genomics: 60
  • Year to date:
    • Site-wide: 1,249
  • Since beginning of last month:
    • Site-wide: 1,942

LD Hub: a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation analysis

bioinformatics more details view paper
  • Downloaded 7,376 times
  • Download rankings, all-time:
    • Site-wide: 1,396
    • In bioinformatics: 84
  • Year to date:
    • Site-wide: 35,232
  • Since beginning of last month:
    • Site-wide: 31,508

Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions.

genetics more details view paper
  • Downloaded 4,611 times
  • Download rankings, all-time:
    • Site-wide: 2,635
    • In genetics: 86
  • Year to date:
    • Site-wide: 39,443
  • Since beginning of last month:
    • Site-wide: 81,529

MR-Base: a platform for systematic causal inference across the phenome using billions of genetic associations

epidemiology more details view paper
  • Downloaded 4,100 times
  • Download rankings, all-time:
    • Site-wide: 3,124
    • In epidemiology: 326
  • Year to date:
    • Site-wide: 31,384
  • Since beginning of last month:
    • Site-wide: 61,911

Phenome-wide Mendelian randomization mapping the influence of the plasma proteome on complex diseases

genetics more details view paper
  • Downloaded 4,030 times
  • Download rankings, all-time:
    • Site-wide: 3,207
    • In genetics: 109
  • Year to date:
    • Site-wide: 10,910
  • Since beginning of last month:
    • Site-wide: 23,447

Automating Mendelian randomization through machine learning to construct a putative causal map of the human phenome

epidemiology more details view paper
  • Downloaded 3,671 times
  • Download rankings, all-time:
    • Site-wide: 3,638
    • In epidemiology: 359
  • Year to date:
    • Site-wide: 10,680
  • Since beginning of last month:
    • Site-wide: 59,158

Why are education, socioeconomic position and intelligence genetically correlated?

genetics more details view paper
  • Downloaded 2,497 times
  • Download rankings, all-time:
    • Site-wide: 6,321
    • In genetics: 274
  • Year to date:
    • Site-wide: 53,942
  • Since beginning of last month:
    • Site-wide: 67,003

Within-family studies for Mendelian randomization: avoiding dynastic, assortative mating, and population stratification biases

genetics more details view paper
  • Downloaded 2,264 times
  • Download rankings, all-time:
    • Site-wide: 7,291
    • In genetics: 323
  • Year to date:
    • Site-wide: 27,657
  • Since beginning of last month:
    • Site-wide: 84,981

Common genetic variants and health outcomes appear geographically structured in the UK Biobank sample: Old concerns returning and their implications.

genetics more details view paper
  • Downloaded 1,901 times
  • Download rankings, all-time:
    • Site-wide: 9,426
    • In genetics: 409
  • Year to date:
    • Site-wide: 70,256
  • Since beginning of last month:
    • Site-wide: 73,017

A transcriptome-wide Mendelian randomization study to uncover tissue-dependent regulatory mechanisms across the human phenome

genetics more details view paper
  • Downloaded 1,641 times
  • Download rankings, all-time:
    • Site-wide: 11,730
    • In genetics: 533
  • Year to date:
    • Site-wide: 128,787
  • Since beginning of last month:
    • Site-wide: 84,097

Genome-wide association studies identify 137 loci for DNA methylation biomarkers of ageing

genetics more details view paper
  • Downloaded 1,443 times
  • Download rankings, all-time:
    • Site-wide: 14,155
    • In genetics: 650
  • Year to date:
    • Site-wide: 6,966
  • Since beginning of last month:
    • Site-wide: 99,398

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

genetics more details view paper
  • Downloaded 1,440 times
  • Download rankings, all-time:
    • Site-wide: 14,202
    • In genetics: 652
  • Year to date:
    • Site-wide: 103,642
  • Since beginning of last month:
    • Site-wide: 60,337

Within-sibship GWAS improve estimates of direct genetic effects

genetics more details view paper
  • Downloaded 1,414 times
  • Download rankings, all-time:
    • Site-wide: 14,589
    • In genetics: 673
  • Year to date:
    • Site-wide: 1,909
  • Since beginning of last month:
    • Site-wide: 10,469

Meffil: efficient normalisation and analysis of very large DNA methylation samples

bioinformatics more details view paper
  • Downloaded 1,348 times
  • Download rankings, all-time:
    • Site-wide: 15,686
    • In bioinformatics: 1,840
  • Year to date:
    • Site-wide: 71,412
  • Since beginning of last month:
    • Site-wide: None

Bayesian reassessment of the epigenetic architecture of complex traits

genomics more details view paper
  • Downloaded 1,339 times
  • Download rankings, all-time:
    • Site-wide: 15,851
    • In genomics: 1,579
  • Year to date:
    • Site-wide: 139,202
  • Since beginning of last month:
    • Site-wide: None

High COVID-19 transmission potential associated with re-opening universities can be mitigated with layered interventions

infectious diseases more details view paper
  • Downloaded 1,319 times
  • Download rankings, all-time:
    • Site-wide: 16,236
    • In infectious diseases: 1,724
  • Year to date:
    • Site-wide: 25,594
  • Since beginning of last month:
    • Site-wide: None

Systematic Mendelian randomization framework elucidates hundreds of genetic loci which may influence disease through changes in DNA methylation levels

genetics more details view paper
  • Downloaded 1,280 times
  • Download rankings, all-time:
    • Site-wide: 16,990
    • In genetics: 793
  • Year to date:
    • Site-wide: 144,426
  • Since beginning of last month:
    • Site-wide: 73,175

Causal epigenome-wide association study identifies CpG sites that influence cardiovascular disease risk

epidemiology more details view paper
  • Downloaded 1,226 times
  • Download rankings, all-time:
    • Site-wide: 18,079
    • In epidemiology: 1,154
  • Year to date:
    • Site-wide: 121,005
  • Since beginning of last month:
    • Site-wide: 75,392

Alcohol consumption and mate choice in UK Biobank: comparing observational and Mendelian randomization estimates

genetics more details view paper
  • Downloaded 1,213 times
  • Download rankings, all-time:
    • Site-wide: 18,363
    • In genetics: 853
  • Year to date:
    • Site-wide: 92,853
  • Since beginning of last month:
    • Site-wide: 80,797

Causal Inference for Heritable Phenotypic Risk Factors Using Heterogeneous Genetic Instruments

genetics more details view paper
  • Downloaded 1,135 times
  • Download rankings, all-time:
    • Site-wide: 20,289
    • In genetics: 937
  • Year to date:
    • Site-wide: 9,000
  • Since beginning of last month:
    • Site-wide: 66,836

PhenoSpD: an integrated toolkit for phenotypic correlation estimation and multiple testing correction using GWAS summary statistics

bioinformatics more details view paper
  • Downloaded 1,089 times
  • Download rankings, all-time:
    • Site-wide: 21,529
    • In bioinformatics: 2,485
  • Year to date:
    • Site-wide: 84,546
  • Since beginning of last month:
    • Site-wide: None

Education, intelligence and Alzheimer's disease: Evidence from a multivariable two-sample Mendelian randomization study

genetics more details view paper
  • Downloaded 1,069 times
  • Download rankings, all-time:
    • Site-wide: 22,115
    • In genetics: 1,014
  • Year to date:
    • Site-wide: 110,596
  • Since beginning of last month:
    • Site-wide: None

Investigating the role of insulin in increased adiposity: Bi-directional Mendelian randomization study

epidemiology more details view paper
  • Downloaded 1,007 times
  • Download rankings, all-time:
    • Site-wide: 24,129
    • In epidemiology: 1,407
  • Year to date:
    • Site-wide: 75,748
  • Since beginning of last month:
    • Site-wide: 75,386

Genomic and phenomic insights from an atlas of genetic effects on DNA methylation

genetic and genomic medicine more details view paper
  • Downloaded 970 times
  • Download rankings, all-time:
    • Site-wide: 25,542
    • In genetic and genomic medicine: 102
  • Year to date:
    • Site-wide: 8,563
  • Since beginning of last month:
    • Site-wide: 27,395

COVID-19 transmission in a university setting: a rapid review of modelling studies

health policy more details view paper
  • Downloaded 950 times
  • Download rankings, all-time:
    • Site-wide: 26,308
    • In health policy: 74
  • Year to date:
    • Site-wide: 21,844
  • Since beginning of last month:
    • Site-wide: 38,013

Tendency towards being a "Morning person" increases risk of Parkinson's disease: evidence from Mendelian randomisation

epidemiology more details view paper
  • Downloaded 886 times
  • Download rankings, all-time:
    • Site-wide: 29,020
    • In epidemiology: 1,570
  • Year to date:
    • Site-wide: 53,900
  • Since beginning of last month:
    • Site-wide: 75,320

Identification of loci where DNA methylation potentially mediates genetic risk of type 1 diabetes

genomics more details view paper
  • Downloaded 867 times
  • Download rankings, all-time:
    • Site-wide: 29,904
    • In genomics: 2,649
  • Year to date:
    • Site-wide: 76,869
  • Since beginning of last month:
    • Site-wide: None

MR-TRYX: A Mendelian randomization framework that exploits horizontal pleiotropy to infer novel causal pathways

bioinformatics more details view paper
  • Downloaded 830 times
  • Download rankings, all-time:
    • Site-wide: 31,798
    • In bioinformatics: 3,553
  • Year to date:
    • Site-wide: 77,016
  • Since beginning of last month:
    • Site-wide: 23,812

The Causal Effect Of Educational Attainment On Alzheimer's Disease: A Two-Sample Mendelian Randomization Study

epidemiology more details view paper
  • Downloaded 805 times
  • Download rankings, all-time:
    • Site-wide: 33,165
    • In epidemiology: 1,715
  • Year to date:
    • Site-wide: 96,828
  • Since beginning of last month:
    • Site-wide: 75,393

The MRC IEU OpenGWAS data infrastructure

genetics more details view paper
  • Downloaded 792 times
  • Download rankings, all-time:
    • Site-wide: 33,915
    • In genetics: 1,550
  • Year to date:
    • Site-wide: 10,222
  • Since beginning of last month:
    • Site-wide: 38,371

The variant call format provides efficient and robust storage of GWAS summary statistics

genetics more details view paper
  • Downloaded 768 times
  • Download rankings, all-time:
    • Site-wide: 35,409
    • In genetics: 1,616
  • Year to date:
    • Site-wide: 24,437
  • Since beginning of last month:
    • Site-wide: 12,598

Using genetic instruments to estimate interactions in Mendelian Randomization studies

epidemiology more details view paper
  • Downloaded 691 times
  • Download rankings, all-time:
    • Site-wide: 40,899
    • In epidemiology: 2,017
  • Year to date:
    • Site-wide: 45,073
  • Since beginning of last month:
    • Site-wide: 33,741

Orienting The Causal Relationship Between Imprecisely Measured Traits Using Genetic Instruments

systems biology more details view paper
  • Downloaded 670 times
  • Download rankings, all-time:
    • Site-wide: 42,572
    • In systems biology: 931
  • Year to date:
    • Site-wide: 132,941
  • Since beginning of last month:
    • Site-wide: None

Appraising the causal relevance of DNA methylation for risk of lung cancer

epidemiology more details view paper
  • Downloaded 663 times
  • Download rankings, all-time:
    • Site-wide: 43,236
    • In epidemiology: 2,101
  • Year to date:
    • Site-wide: 115,127
  • Since beginning of last month:
    • Site-wide: 75,318

Is disrupted sleep a risk factor for Alzheimers disease? Evidence from a two-sample Mendelian randomization analysis

epidemiology more details view paper
  • Downloaded 588 times
  • Download rankings, all-time:
    • Site-wide: 50,296
    • In epidemiology: 2,345
  • Year to date:
    • Site-wide: 132,797
  • Since beginning of last month:
    • Site-wide: 66,452

The Parkinsons Disease Mendelian Randomization Research Portal

neuroscience more details view paper
  • Downloaded 523 times
  • Download rankings, all-time:
    • Site-wide: 58,002
    • In neuroscience: 8,490
  • Year to date:
    • Site-wide: 134,118
  • Since beginning of last month:
    • Site-wide: 84,992

Systematic evaluation of the causal relationship between DNA methylation and C-reactive protein

genetics more details view paper
  • Downloaded 515 times
  • Download rankings, all-time:
    • Site-wide: 59,107
    • In genetics: 2,616
  • Year to date:
    • Site-wide: 79,016
  • Since beginning of last month:
    • Site-wide: 79,846

What explains the effect of education on cardiovascular disease? Applying Mendelian randomization to identify the consequences of education inequality

epidemiology more details view paper
  • Downloaded 513 times
  • Download rankings, all-time:
    • Site-wide: 59,367
    • In epidemiology: 2,657
  • Year to date:
    • Site-wide: 144,970
  • Since beginning of last month:
    • Site-wide: None

Prenatal alcohol exposure and facial morphology in a UK cohort

epidemiology more details view paper
  • Downloaded 495 times
  • Download rankings, all-time:
    • Site-wide: 61,772
    • In epidemiology: 2,741
  • Year to date:
    • Site-wide: 78,117
  • Since beginning of last month:
    • Site-wide: 24,398

Investigating the shared genetics of non-syndromic cleft lip/palate and facial morphology

genetics more details view paper
  • Downloaded 468 times
  • Download rankings, all-time:
    • Site-wide: 65,668
    • In genetics: 2,887
  • Year to date:
    • Site-wide: 146,260
  • Since beginning of last month:
    • Site-wide: 73,112

Schizophrenia risk and reproductive success: A Mendelian randomization study.

evolutionary biology more details view paper
  • Downloaded 441 times
  • Download rankings, all-time:
    • Site-wide: 69,935
    • In evolutionary biology: 3,654
  • Year to date:
    • Site-wide: 134,603
  • Since beginning of last month:
    • Site-wide: None

The use of negative control outcomes in Mendelian Randomisation to detect potential population stratification or selection bias.

genetics more details view paper
  • Downloaded 433 times
  • Download rankings, all-time:
    • Site-wide: 71,323
    • In genetics: 3,147
  • Year to date:
    • Site-wide: 67,697
  • Since beginning of last month:
    • Site-wide: 21,092

Does Neuroticism Cause Depression? A Mendelian Randomization Study

genetics more details view paper
  • Downloaded 428 times
  • Download rankings, all-time:
    • Site-wide: 72,131
    • In genetics: 3,171
  • Year to date:
    • Site-wide: 150,461
  • Since beginning of last month:
    • Site-wide: None

Assortative mating and within-spouse pair comparisons

genetics more details view paper
  • Downloaded 427 times
  • Download rankings, all-time:
    • Site-wide: 72,300
    • In genetics: 3,178
  • Year to date:
    • Site-wide: 63,248
  • Since beginning of last month:
    • Site-wide: 95,826

The role of glycaemic and lipid risk factors in mediating the effect of BMI on coronary heart disease: A two-step, two-sample Mendelian randomization study

epidemiology more details view paper
  • Downloaded 422 times
  • Download rankings, all-time:
    • Site-wide: 73,117
    • In epidemiology: 3,158
  • Year to date:
    • Site-wide: 133,220
  • Since beginning of last month:
    • Site-wide: None

The effect of plasma lipids and lipid lowering interventions on bone mineral density: a Mendelian randomization study

epidemiology more details view paper
  • Downloaded 377 times
  • Download rankings, all-time:
    • Site-wide: 81,271
    • In epidemiology: 3,443
  • Year to date:
    • Site-wide: 136,126
  • Since beginning of last month:
    • Site-wide: None

Partitioning Phenotypic Variance Due To Parent-Of-Origin Effects Using Genomic Relatedness Matrices

genetics more details view paper
  • Downloaded 375 times
  • Download rankings, all-time:
    • Site-wide: 81,639
    • In genetics: 3,561
  • Year to date:
    • Site-wide: 144,409
  • Since beginning of last month:
    • Site-wide: None

University students and staff able to maintain low daily contact numbers during various COVID-19 guideline periods

epidemiology more details view paper
  • Downloaded 359 times
  • Download rankings, all-time:
    • Site-wide: 84,721
    • In epidemiology: 3,582
  • Year to date:
    • Site-wide: 13,733
  • Since beginning of last month:
    • Site-wide: 19,293

DNA methylation mediates genetic liability to non-syndromic cleft lip/palate

genetics more details view paper
  • Downloaded 358 times
  • Download rankings, all-time:
    • Site-wide: 84,976
    • In genetics: 3,714
  • Year to date:
    • Site-wide: 134,605
  • Since beginning of last month:
    • Site-wide: 73,110

Investigating DNA methylation as a potential mediator between pigmentation genes, pigmentary traits and skin cancer

genetics more details view paper
  • Downloaded 329 times
  • Download rankings, all-time:
    • Site-wide: 91,124
    • In genetics: 3,950
  • Year to date:
    • Site-wide: 60,516
  • Since beginning of last month:
    • Site-wide: 34,315

Contacts and behaviours of university students during the COVID-19 pandemic at the start of the 2020/21 academic year

public and global health more details view paper
  • Downloaded 324 times
  • Download rankings, all-time:
    • Site-wide: 92,339
    • In public and global health: 1,165
  • Year to date:
    • Site-wide: 25,495
  • Since beginning of last month:
    • Site-wide: 107,928

Modelling pooling strategies for SARS-CoV-2 testing in a university setting

infectious diseases more details view paper
  • Downloaded 299 times
  • Download rankings, all-time:
    • Site-wide: 97,732
    • In infectious diseases: 4,258
  • Year to date:
    • Site-wide: 17,825
  • Since beginning of last month:
    • Site-wide: None

EpiGraphDB: a database and data mining platform for health data science

bioinformatics more details view paper
  • Downloaded 254 times
  • Download rankings, all-time:
    • Site-wide: 108,497
    • In bioinformatics: 9,160
  • Year to date:
    • Site-wide: 122,586
  • Since beginning of last month:
    • Site-wide: 100,610

The association of DNA methylation with body mass index: distinguishing between predictors and biomarkers

genetics more details view paper
  • Downloaded 201 times
  • Download rankings, all-time:
    • Site-wide: 121,623
    • In genetics: 5,051
  • Year to date:
    • Site-wide: 147,126
  • Since beginning of last month:
    • Site-wide: 93,627

Limits of lockdown: characterising essential contacts during strict physical distancing

epidemiology more details view paper
  • Downloaded 151 times
  • Download rankings, all-time:
    • Site-wide: 133,310
    • In epidemiology: 5,532
  • Year to date:
    • Site-wide: 41,987
  • Since beginning of last month:
    • Site-wide: 111,176

Exploring the variance in complex traits captured by DNA methylation assays

genetics more details view paper
  • Downloaded 138 times
  • Download rankings, all-time:
    • Site-wide: 136,330
    • In genetics: 5,496
  • Year to date:
    • Site-wide: 109,586
  • Since beginning of last month:
    • Site-wide: 50,175

Genetic analyses of common infections in the Avon Longitudinal Study of Parents and Children cohort

epidemiology more details view paper
  • Downloaded 73 times
  • Download rankings, all-time:
    • Site-wide: 147,789
    • In epidemiology: 6,083
  • Year to date:
    • Site-wide: 82,542
  • Since beginning of last month:
    • Site-wide: 42,954

DNA methylome-wide association study of genetic risk for depression implicates antigen processing and immune responses

psychiatry and clinical psychology more details view paper
  • Downloaded 71 times
  • Download rankings, all-time:
    • Site-wide: 148,028
    • In psychiatry and clinical psychology: 901
  • Year to date:
    • Site-wide: 83,990
  • Since beginning of last month:
    • Site-wide: 115,258

Navigating sample overlap, winner's curse and weak instrument bias in Mendelian randomization studies using the UK Biobank

epidemiology more details view paper
  • Downloaded 48 times
  • Download rankings, all-time:
    • Site-wide: 150,307
    • In epidemiology: 6,186
  • Year to date:
    • Site-wide: 108,628
  • Since beginning of last month:
    • Site-wide: 17,844

Design and quality control of large-scale two-sample Mendelian randomisation studies

epidemiology more details view paper
  • Downloaded 2 times
  • Download rankings, all-time:
    • Site-wide: 154,106
    • In epidemiology: 6,355
  • Year to date:
    • Site-wide: 154,252
  • Since beginning of last month:
    • Site-wide: 42,489

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