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Author: Gibran Hemani

Rankings

  • All-time downloads: 112,527 (rank: 1,715 )
  • Categories:
    • bioinformatics: 11,672 (rank: 989 )
    • epidemiology: 33,618 (rank: 777 )
    • evolutionary biology: 487 (rank: 19,955 (tie) )
    • genetic and genomic medicine: 4,088 (rank: 1,257 )
    • genetics: 37,988 (rank: 175 )
    • genomics: 15,114 (rank: 1,431 )
    • health policy: 1,206 (rank: 631 (tie) )
    • infectious diseases: 2,332 (rank: 21,971 (tie) )
    • neuroscience: 573 (rank: 61,030 (tie) )
    • psychiatry and clinical psychology: 273 (rank: 7,817 (tie) )
    • public and global health: 436 (rank: 12,398 (tie) )
    • systems biology: 750 (rank: 8,562 (tie) )

Downloads per author, site-wide

Preprints

Review and further developments in statistical corrections for Winner's Curse in genetic association studies

genetics more details view paper

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Collider bias undermines our understanding of COVID-19 disease risk and severity

epidemiology more details view paper
  • Downloaded 13,627 times
  • Download rankings, all-time:
    • Site-wide: 907
    • In epidemiology: 134
  • Year to date:
    • Site-wide: 7,204
  • Since beginning of last month:
    • Site-wide: 11,498

Unraveling the polygenic architecture of complex traits using blood eQTL meta-analysis

genomics more details view paper
  • Downloaded 13,011 times
  • Download rankings, all-time:
    • Site-wide: 974
    • In genomics: 54
  • Year to date:
    • Site-wide: 3,537
  • Since beginning of last month:
    • Site-wide: 1,564

LD Hub: a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation analysis

bioinformatics more details view paper
  • Downloaded 7,568 times
  • Download rankings, all-time:
    • Site-wide: 1,942
    • In bioinformatics: 99
  • Year to date:
    • Site-wide: 84,782
  • Since beginning of last month:
    • Site-wide: None

Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions.

genetics more details view paper
  • Downloaded 4,860 times
  • Download rankings, all-time:
    • Site-wide: 3,544
    • In genetics: 97
  • Year to date:
    • Site-wide: 63,851
  • Since beginning of last month:
    • Site-wide: 74,898

Automating Mendelian randomization through machine learning to construct a putative causal map of the human phenome

epidemiology more details view paper
  • Downloaded 4,525 times
  • Download rankings, all-time:
    • Site-wide: 3,900
    • In epidemiology: 419
  • Year to date:
    • Site-wide: 8,062
  • Since beginning of last month:
    • Site-wide: 4,824

Phenome-wide Mendelian randomization mapping the influence of the plasma proteome on complex diseases

genetics more details view paper
  • Downloaded 4,470 times
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    • Site-wide: 3,960
    • In genetics: 112
  • Year to date:
    • Site-wide: 24,304
  • Since beginning of last month:
    • Site-wide: 12,118

MR-Base: a platform for systematic causal inference across the phenome using billions of genetic associations

epidemiology more details view paper
  • Downloaded 4,376 times
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    • Site-wide: 4,095
    • In epidemiology: 420
  • Year to date:
    • Site-wide: 63,166
  • Since beginning of last month:
    • Site-wide: 20,649

Within-sibship GWAS improve estimates of direct genetic effects

genetics more details view paper
  • Downloaded 3,586 times
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    • Site-wide: 5,462
    • In genetics: 188
  • Year to date:
    • Site-wide: 3,285
  • Since beginning of last month:
    • Site-wide: 13,241

Why are education, socioeconomic position and intelligence genetically correlated?

genetics more details view paper
  • Downloaded 2,770 times
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    • Site-wide: 7,976
    • In genetics: 292
  • Year to date:
    • Site-wide: 56,173
  • Since beginning of last month:
    • Site-wide: 59,281

Within-family studies for Mendelian randomization: avoiding dynastic, assortative mating, and population stratification biases

genetics more details view paper
  • Downloaded 2,561 times
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    • Site-wide: 8,974
    • In genetics: 349
  • Year to date:
    • Site-wide: 50,288
  • Since beginning of last month:
    • Site-wide: 11,349

Proteome-wide Mendelian randomization in global biobank meta-analysis reveals multi-ancestry drug targets for common diseases

genetic and genomic medicine more details view paper
  • Downloaded 2,543 times
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    • Site-wide: 9,063
    • In genetic and genomic medicine: 58
  • Year to date:
    • Site-wide: 828
  • Since beginning of last month:
    • Site-wide: 5,732

The MRC IEU OpenGWAS data infrastructure

genetics more details view paper
  • Downloaded 2,084 times
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    • Site-wide: 12,253
    • In genetics: 555
  • Year to date:
    • Site-wide: 3,944
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    • Site-wide: 10,656

Common genetic variants and health outcomes appear geographically structured in the UK Biobank sample: Old concerns returning and their implications.

genetics more details view paper
  • Downloaded 2,021 times
  • Download rankings, all-time:
    • Site-wide: 12,827
    • In genetics: 477
  • Year to date:
    • Site-wide: 155,823
  • Since beginning of last month:
    • Site-wide: 51,477

A transcriptome-wide Mendelian randomization study to uncover tissue-dependent regulatory mechanisms across the human phenome

genetics more details view paper
  • Downloaded 1,720 times
  • Download rankings, all-time:
    • Site-wide: 16,387
    • In genetics: 644
  • Year to date:
    • Site-wide: 159,903
  • Since beginning of last month:
    • Site-wide: 101,921

Genome-wide association studies identify 137 loci for DNA methylation biomarkers of ageing

genetics more details view paper
  • Downloaded 1,693 times
  • Download rankings, all-time:
    • Site-wide: 16,798
    • In genetics: 677
  • Year to date:
    • Site-wide: 70,514
  • Since beginning of last month:
    • Site-wide: 53,689

Causal Inference for Heritable Phenotypic Risk Factors Using Heterogeneous Genetic Instruments

genetics more details view paper
  • Downloaded 1,675 times
  • Download rankings, all-time:
    • Site-wide: 17,073
    • In genetics: 712
  • Year to date:
    • Site-wide: 21,399
  • Since beginning of last month:
    • Site-wide: 41,680

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

genetics more details view paper
  • Downloaded 1,520 times
  • Download rankings, all-time:
    • Site-wide: 19,900
    • In genetics: 795
  • Year to date:
    • Site-wide: 161,822
  • Since beginning of last month:
    • Site-wide: 132,481

High COVID-19 transmission potential associated with re-opening universities can be mitigated with layered interventions

infectious diseases more details view paper
  • Downloaded 1,505 times
  • Download rankings, all-time:
    • Site-wide: 20,227
    • In infectious diseases: 2,266
  • Year to date:
    • Site-wide: 112,152
  • Since beginning of last month:
    • Site-wide: None

Meffil: efficient normalisation and analysis of very large DNA methylation samples

bioinformatics more details view paper
  • Downloaded 1,488 times
  • Download rankings, all-time:
    • Site-wide: 20,625
    • In bioinformatics: 2,170
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    • Site-wide: 105,921
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    • Site-wide: None

Genomic and phenomic insights from an atlas of genetic effects on DNA methylation

genetic and genomic medicine more details view paper
  • Downloaded 1,459 times
  • Download rankings, all-time:
    • Site-wide: 21,275
    • In genetic and genomic medicine: 121
  • Year to date:
    • Site-wide: 55,185
  • Since beginning of last month:
    • Site-wide: 156,693

Bayesian reassessment of the epigenetic architecture of complex traits

genomics more details view paper
  • Downloaded 1,409 times
  • Download rankings, all-time:
    • Site-wide: 22,491
    • In genomics: 1,929
  • Year to date:
    • Site-wide: 169,560
  • Since beginning of last month:
    • Site-wide: 74,732

Systematic Mendelian randomization framework elucidates hundreds of genetic loci which may influence disease through changes in DNA methylation levels

genetics more details view paper
  • Downloaded 1,329 times
  • Download rankings, all-time:
    • Site-wide: 24,683
    • In genetics: 960
  • Year to date:
    • Site-wide: 203,459
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    • Site-wide: None

Alcohol consumption and mate choice in UK Biobank: comparing observational and Mendelian randomization estimates

genetics more details view paper
  • Downloaded 1,310 times
  • Download rankings, all-time:
    • Site-wide: 25,257
    • In genetics: 990
  • Year to date:
    • Site-wide: 149,658
  • Since beginning of last month:
    • Site-wide: 50,962

Causal epigenome-wide association study identifies CpG sites that influence cardiovascular disease risk

epidemiology more details view paper
  • Downloaded 1,293 times
  • Download rankings, all-time:
    • Site-wide: 25,797
    • In epidemiology: 1,517
  • Year to date:
    • Site-wide: 180,451
  • Since beginning of last month:
    • Site-wide: 75,897

COVID-19 transmission in a university setting: a rapid review of modelling studies

health policy more details view paper
  • Downloaded 1,238 times
  • Download rankings, all-time:
    • Site-wide: 27,622
    • In health policy: 85
  • Year to date:
    • Site-wide: 76,008
  • Since beginning of last month:
    • Site-wide: 156,852

PhenoSpD: an integrated toolkit for phenotypic correlation estimation and multiple testing correction using GWAS summary statistics

bioinformatics more details view paper
  • Downloaded 1,229 times
  • Download rankings, all-time:
    • Site-wide: 27,954
    • In bioinformatics: 2,983
  • Year to date:
    • Site-wide: 107,948
  • Since beginning of last month:
    • Site-wide: 13,571

Investigating the role of insulin in increased adiposity: Bi-directional Mendelian randomization study

epidemiology more details view paper
  • Downloaded 1,149 times
  • Download rankings, all-time:
    • Site-wide: 31,046
    • In epidemiology: 1,747
  • Year to date:
    • Site-wide: 127,039
  • Since beginning of last month:
    • Site-wide: 33,725

Education, intelligence and Alzheimer's disease: Evidence from a multivariable two-sample Mendelian randomization study

genetics more details view paper
  • Downloaded 1,134 times
  • Download rankings, all-time:
    • Site-wide: 31,715
    • In genetics: 1,254
  • Year to date:
    • Site-wide: 182,937
  • Since beginning of last month:
    • Site-wide: 100,388

Identification of loci where DNA methylation potentially mediates genetic risk of type 1 diabetes

genomics more details view paper
  • Downloaded 1,084 times
  • Download rankings, all-time:
    • Site-wide: 33,978
    • In genomics: 2,790
  • Year to date:
    • Site-wide: 78,118
  • Since beginning of last month:
    • Site-wide: 28,186

University students and staff able to maintain low daily contact numbers during various COVID-19 guideline periods

epidemiology more details view paper
  • Downloaded 1,065 times
  • Download rankings, all-time:
    • Site-wide: 34,898
    • In epidemiology: 2,143
  • Year to date:
    • Site-wide: 9,517
  • Since beginning of last month:
    • Site-wide: 107,977

Tendency towards being a "Morning person" increases risk of Parkinson's disease: evidence from Mendelian randomisation

epidemiology more details view paper
  • Downloaded 1,029 times
  • Download rankings, all-time:
    • Site-wide: 36,807
    • In epidemiology: 1,941
  • Year to date:
    • Site-wide: 118,857
  • Since beginning of last month:
    • Site-wide: 59,549

Using genetic instruments to estimate interactions in Mendelian Randomization studies

epidemiology more details view paper
  • Downloaded 1,008 times
  • Download rankings, all-time:
    • Site-wide: 37,998
    • In epidemiology: 2,007
  • Year to date:
    • Site-wide: 63,883
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    • Site-wide: None

The variant call format provides efficient and robust storage of GWAS summary statistics

genetics more details view paper
  • Downloaded 999 times
  • Download rankings, all-time:
    • Site-wide: 38,514
    • In genetics: 1,542
  • Year to date:
    • Site-wide: 71,417
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    • Site-wide: None

MR-TRYX: A Mendelian randomization framework that exploits horizontal pleiotropy to infer novel causal pathways

bioinformatics more details view paper
  • Downloaded 971 times
  • Download rankings, all-time:
    • Site-wide: 40,229
    • In bioinformatics: 4,053
  • Year to date:
    • Site-wide: 141,992
  • Since beginning of last month:
    • Site-wide: 174,193

The Causal Effect Of Educational Attainment On Alzheimer's Disease: A Two-Sample Mendelian Randomization Study

epidemiology more details view paper
  • Downloaded 960 times
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    • Site-wide: 40,988
    • In epidemiology: 2,109
  • Year to date:
    • Site-wide: 112,587
  • Since beginning of last month:
    • Site-wide: 49,518

Orienting The Causal Relationship Between Imprecisely Measured Traits Using Genetic Instruments

systems biology more details view paper
  • Downloaded 768 times
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    • Site-wide: 57,293
    • In systems biology: 1,118
  • Year to date:
    • Site-wide: 143,848
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    • Site-wide: 73,987

Appraising the causal relevance of DNA methylation for risk of lung cancer

epidemiology more details view paper
  • Downloaded 762 times
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    • Site-wide: 57,990
    • In epidemiology: 2,759
  • Year to date:
    • Site-wide: 122,829
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    • Site-wide: 39,590

Prenatal alcohol exposure and facial morphology in a UK cohort

epidemiology more details view paper
  • Downloaded 733 times
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    • Site-wide: 61,418
    • In epidemiology: 2,951
  • Year to date:
    • Site-wide: 81,903
  • Since beginning of last month:
    • Site-wide: 80,080

Is disrupted sleep a risk factor for Alzheimers disease? Evidence from a two-sample Mendelian randomization analysis

epidemiology more details view paper
  • Downloaded 647 times
  • Download rankings, all-time:
    • Site-wide: 73,093
    • In epidemiology: 3,265
  • Year to date:
    • Site-wide: 203,463
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    • Site-wide: 100,036

Systematic evaluation of the causal relationship between DNA methylation and C-reactive protein

genetics more details view paper
  • Downloaded 646 times
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    • Site-wide: 73,321
    • In genetics: 2,845
  • Year to date:
    • Site-wide: 139,096
  • Since beginning of last month:
    • Site-wide: 48,823

What explains the effect of education on cardiovascular disease? Applying Mendelian randomization to identify the consequences of education inequality

epidemiology more details view paper
  • Downloaded 605 times
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    • Site-wide: 79,626
    • In epidemiology: 3,550
  • Year to date:
    • Site-wide: 160,053
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    • Site-wide: 101,541

Assortative mating and within-spouse pair comparisons

genetics more details view paper
  • Downloaded 592 times
  • Download rankings, all-time:
    • Site-wide: 81,854
    • In genetics: 3,160
  • Year to date:
    • Site-wide: 125,777
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    • Site-wide: 110,113

The Parkinsons Disease Mendelian Randomization Research Portal

neuroscience more details view paper
  • Downloaded 591 times
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    • Site-wide: 81,976
    • In neuroscience: 11,355
  • Year to date:
    • Site-wide: 169,276
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    • Site-wide: 130,108

Navigating sample overlap, winner's curse and weak instrument bias in Mendelian randomization studies using the UK Biobank

epidemiology more details view paper
  • Downloaded 575 times
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    • Site-wide: 85,017
    • In epidemiology: 4,350
  • Year to date:
    • Site-wide: 15,361
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    • Site-wide: 14,103

The use of negative control outcomes in Mendelian Randomisation to detect potential population stratification or selection bias.

genetics more details view paper
  • Downloaded 559 times
  • Download rankings, all-time:
    • Site-wide: 87,991
    • In genetics: 3,345
  • Year to date:
    • Site-wide: 135,204
  • Since beginning of last month:
    • Site-wide: 140,750

Investigating the shared genetics of non-syndromic cleft lip/palate and facial morphology

genetics more details view paper
  • Downloaded 524 times
  • Download rankings, all-time:
    • Site-wide: 95,041
    • In genetics: 3,565
  • Year to date:
    • Site-wide: 195,424
  • Since beginning of last month:
    • Site-wide: 123,459

Does Neuroticism Cause Depression? A Mendelian Randomization Study

genetics more details view paper
  • Downloaded 524 times
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    • Site-wide: 95,099
    • In genetics: 3,607
  • Year to date:
    • Site-wide: 166,610
  • Since beginning of last month:
    • Site-wide: 101,309

Schizophrenia risk and reproductive success: A Mendelian randomization study.

evolutionary biology more details view paper
  • Downloaded 508 times
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    • Site-wide: 98,561
    • In evolutionary biology: 4,473
  • Year to date:
    • Site-wide: 183,312
  • Since beginning of last month:
    • Site-wide: 129,434

Impacts of vaccination and asymptomatic testing on SARS-CoV-2 transmission dynamics in a university setting

infectious diseases more details view paper
  • Downloaded 466 times
  • Download rankings, all-time:
    • Site-wide: 108,210
    • In infectious diseases: 5,583
  • Year to date:
    • Site-wide: 54,328
  • Since beginning of last month:
    • Site-wide: 88,767

The role of glycaemic and lipid risk factors in mediating the effect of BMI on coronary heart disease: A two-step, two-sample Mendelian randomization study

epidemiology more details view paper
  • Downloaded 466 times
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    • Site-wide: 108,340
    • In epidemiology: 4,476
  • Year to date:
    • Site-wide: 207,958
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    • Site-wide: None

The effect of plasma lipids and lipid lowering interventions on bone mineral density: a Mendelian randomization study

epidemiology more details view paper
  • Downloaded 458 times
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    • Site-wide: 110,216
    • In epidemiology: 4,558
  • Year to date:
    • Site-wide: 193,208
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Contacts and behaviours of university students during the COVID-19 pandemic at the start of the 2020/21 academic year

public and global health more details view paper
  • Downloaded 456 times
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    • Site-wide: 110,708
    • In public and global health: 1,626
  • Year to date:
    • Site-wide: 123,645
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    • Site-wide: 166,040

Partitioning Phenotypic Variance Due To Parent-Of-Origin Effects Using Genomic Relatedness Matrices

genetics more details view paper
  • Downloaded 454 times
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    • Site-wide: 111,184
    • In genetics: 4,170
  • Year to date:
    • Site-wide: 198,704
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    • Site-wide: 79,509

DNA methylation mediates genetic liability to non-syndromic cleft lip/palate

genetics more details view paper
  • Downloaded 451 times
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    • Site-wide: 111,895
    • In genetics: 4,230
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    • Site-wide: 166,567
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    • Site-wide: 79,448

Investigating DNA methylation as a potential mediator between pigmentation genes, pigmentary traits and skin cancer

genetics more details view paper
  • Downloaded 433 times
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    • Site-wide: 116,336
    • In genetics: 4,265
  • Year to date:
    • Site-wide: 160,946
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    • Site-wide: None

Modelling pooling strategies for SARS-CoV-2 testing in a university setting

infectious diseases more details view paper
  • Downloaded 428 times
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    • Site-wide: 117,746
    • In infectious diseases: 5,796
  • Year to date:
    • Site-wide: 157,307
  • Since beginning of last month:
    • Site-wide: 167,359

The Norwegian Mother, Father, and Child cohort study (MoBa) genotyping data resource: MoBaPsychGen pipeline v.1

genetics more details view paper
  • Downloaded 409 times
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    • Site-wide: 122,752
    • In genetics: 6,457
  • Year to date:
    • Site-wide: 15,253
  • Since beginning of last month:
    • Site-wide: 4,456

Limits of lockdown: characterising essential contacts during strict physical distancing

epidemiology more details view paper
  • Downloaded 367 times
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    • Site-wide: 134,640
    • In epidemiology: 5,448
  • Year to date:
    • Site-wide: 69,300
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    • Site-wide: 169,570

Design and quality control of large-scale two-sample Mendelian randomisation studies

epidemiology more details view paper
  • Downloaded 347 times
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    • Site-wide: 140,631
    • In epidemiology: 5,964
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    • Site-wide: 55,534
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    • Site-wide: 58,115

EpiGraphDB: a database and data mining platform for health data science

bioinformatics more details view paper
  • Downloaded 323 times
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    • Site-wide: 147,850
    • In bioinformatics: 11,266
  • Year to date:
    • Site-wide: 184,456
  • Since beginning of last month:
    • Site-wide: 114,781

Evidence of positive and negative selection associated with DNA methylation

genetics more details view paper
  • Downloaded 317 times
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    • Site-wide: 149,776
    • In genetics: 5,625
  • Year to date:
    • Site-wide: 82,152
  • Since beginning of last month:
    • Site-wide: 169,616

DNA methylome-wide association study of genetic risk for depression implicates antigen processing and immune responses

psychiatry and clinical psychology more details view paper
  • Downloaded 302 times
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    • Site-wide: 154,194
    • In psychiatry and clinical psychology: 934
  • Year to date:
    • Site-wide: 92,776
  • Since beginning of last month:
    • Site-wide: 133,651

An efficient and robust tool for colocalisation: Pair-wise Conditional and Colocalisation (PWCoCo)

bioinformatics more details view paper
  • Downloaded 295 times
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    • Site-wide: 156,320
    • In bioinformatics: 14,288
  • Year to date:
    • Site-wide: 25,783
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    • Site-wide: 173,157

The association of DNA methylation with body mass index: distinguishing between predictors and biomarkers

genetics more details view paper
  • Downloaded 276 times
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    • Site-wide: 161,736
    • In genetics: 5,850
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    • Site-wide: 191,996
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    • Site-wide: 162,074

Exploring the variance in complex traits captured by DNA methylation assays

genetics more details view paper
  • Downloaded 273 times
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    • Site-wide: 162,607
    • In genetics: 6,065
  • Year to date:
    • Site-wide: 135,354
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    • Site-wide: 42,357

Evaluating and implementing block jackknife resampling Mendelian randomization to mitigate bias induced by overlapping samples

genetic and genomic medicine more details view paper
  • Downloaded 270 times
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    • Site-wide: 163,612
    • In genetic and genomic medicine: 1,192
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    • Site-wide: 43,814
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    • Site-wide: 44,274

Evaluating the potential benefits and pitfalls of combining protein and expression quantitative trait loci in evidencing drug targets

genetics more details view paper
  • Downloaded 261 times
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    • Site-wide: 166,216
    • In genetics: 6,247
  • Year to date:
    • Site-wide: 31,076
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    • Site-wide: 85,955

DNA co-methylation has a stable structure and is related to specific aspects of genome regulation

bioinformatics more details view paper
  • Downloaded 251 times
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    • Site-wide: 168,863
    • In bioinformatics: 12,764
  • Year to date:
    • Site-wide: 32,754
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    • Site-wide: 71,398

Trans-ancestry meta-analysis improves performance of genetic scores for multiple adiposity-related traits in East Asian populations

genetic and genomic medicine more details view paper
  • Downloaded 225 times
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    • Site-wide: 176,022
    • In genetic and genomic medicine: 1,344
  • Year to date:
    • Site-wide: 38,617
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    • Site-wide: 19,992

Genetic analyses of common infections in the Avon Longitudinal Study of Parents and Children cohort

epidemiology more details view paper
  • Downloaded 206 times
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    • Site-wide: 180,816
    • In epidemiology: 7,094
  • Year to date:
    • Site-wide: 177,376
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    • Site-wide: 188,254

Investigating the transparency of reporting in two-sample summary data Mendelian randomization studies

epidemiology more details view paper
  • Downloaded 202 times
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    • Site-wide: 181,629
    • In epidemiology: 7,171
  • Year to date:
    • Site-wide: 117,141
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    • Site-wide: 177,446

A comparison of the genes and genesets identified by EWAS and GWAS of fourteen complex traits

epidemiology more details view paper
  • Downloaded 175 times
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The impact of fatty acids biosynthesis on the risk of cardiovascular diseases in Europeans and East Asians: A Mendelian randomization study

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