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Author: Gilbran Hemani

Rankings

  • All-time downloads: 87,159 (rank: 1,590 )
  • Categories:
    • bioinformatics: 10,808 (rank: 731 (tie) )
    • epidemiology: 27,914 (rank: 572 )
    • evolutionary biology: 437 (rank: 15,589 (tie) )
    • genetic and genomic medicine: 874 (rank: 3,396 (tie) )
    • genetics: 30,257 (rank: 208 )
    • genomics: 12,924 (rank: 1,422 )
    • health policy: 907 (rank: 510 (tie) )
    • infectious diseases: 1,561 (rank: 18,275 (tie) )
    • neuroscience: 516 (rank: 44,720 (tie) )
    • public and global health: 302 (rank: 8,144 (tie) )
    • systems biology: 659 (rank: 6,849 (tie) )

Downloads per author, site-wide

Preprints

Collider bias undermines our understanding of COVID-19 disease risk and severity

epidemiology more details view paper
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    • Site-wide: 670
    • In epidemiology: 99
  • Year to date:
    • Site-wide: 2,683
  • Since beginning of last month:
    • Site-wide: 2,983

Unraveling the polygenic architecture of complex traits using blood eQTL meta-analysis

genomics more details view paper
  • Downloaded 10,737 times
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    • Site-wide: 810
    • In genomics: 59
  • Year to date:
    • Site-wide: 1,141
  • Since beginning of last month:
    • Site-wide: 932

LD Hub: a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation analysis

bioinformatics more details view paper
  • Downloaded 7,341 times
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    • Site-wide: 1,307
    • In bioinformatics: 80
  • Year to date:
    • Site-wide: 32,680
  • Since beginning of last month:
    • Site-wide: 45,287

Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions.

genetics more details view paper
  • Downloaded 4,581 times
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    • Site-wide: 2,472
    • In genetics: 87
  • Year to date:
    • Site-wide: 36,008
  • Since beginning of last month:
    • Site-wide: 40,130

MR-Base: a platform for systematic causal inference across the phenome using billions of genetic associations

epidemiology more details view paper
  • Downloaded 4,079 times
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    • Site-wide: 2,915
    • In epidemiology: 303
  • Year to date:
    • Site-wide: 26,147
  • Since beginning of last month:
    • Site-wide: 26,651

Phenome-wide Mendelian randomization mapping the influence of the plasma proteome on complex diseases

genetics more details view paper
  • Downloaded 3,961 times
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    • Site-wide: 3,057
    • In genetics: 112
  • Year to date:
    • Site-wide: 9,875
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    • Site-wide: 11,253

Automating Mendelian randomization through machine learning to construct a putative causal map of the human phenome

epidemiology more details view paper
  • Downloaded 3,570 times
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    • Site-wide: 3,554
    • In epidemiology: 345
  • Year to date:
    • Site-wide: 11,024
  • Since beginning of last month:
    • Site-wide: 13,571

Why are education, socioeconomic position and intelligence genetically correlated?

genetics more details view paper
  • Downloaded 2,474 times
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    • Site-wide: 6,016
    • In genetics: 269
  • Year to date:
    • Site-wide: 48,574
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    • Site-wide: 50,696

Within-family studies for Mendelian randomization: avoiding dynastic, assortative mating, and population stratification biases

genetics more details view paper
  • Downloaded 2,228 times
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    • Site-wide: 6,997
    • In genetics: 325
  • Year to date:
    • Site-wide: 24,864
  • Since beginning of last month:
    • Site-wide: 27,582

Common genetic variants and health outcomes appear geographically structured in the UK Biobank sample: Old concerns returning and their implications.

genetics more details view paper
  • Downloaded 1,883 times
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    • Site-wide: 8,956
    • In genetics: 402
  • Year to date:
    • Site-wide: 63,621
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    • Site-wide: 88,930

A transcriptome-wide Mendelian randomization study to uncover tissue-dependent regulatory mechanisms across the human phenome

genetics more details view paper
  • Downloaded 1,631 times
  • Download rankings, all-time:
    • Site-wide: 11,079
    • In genetics: 515
  • Year to date:
    • Site-wide: 125,254
  • Since beginning of last month:
    • Site-wide: 114,049

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

genetics more details view paper
  • Downloaded 1,434 times
  • Download rankings, all-time:
    • Site-wide: 13,442
    • In genetics: 630
  • Year to date:
    • Site-wide: 89,126
  • Since beginning of last month:
    • Site-wide: 115,393

Genome-wide association studies identify 137 loci for DNA methylation biomarkers of ageing

genetics more details view paper
  • Downloaded 1,342 times
  • Download rankings, all-time:
    • Site-wide: 14,816
    • In genetics: 705
  • Year to date:
    • Site-wide: 6,514
  • Since beginning of last month:
    • Site-wide: 8,683

Bayesian reassessment of the epigenetic architecture of complex traits

genomics more details view paper
  • Downloaded 1,334 times
  • Download rankings, all-time:
    • Site-wide: 14,965
    • In genomics: 1,524
  • Year to date:
    • Site-wide: 128,784
  • Since beginning of last month:
    • Site-wide: 138,560

Meffil: efficient normalisation and analysis of very large DNA methylation samples

bioinformatics more details view paper
  • Downloaded 1,321 times
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    • Site-wide: 15,163
    • In bioinformatics: 1,804
  • Year to date:
    • Site-wide: 72,513
  • Since beginning of last month:
    • Site-wide: 90,005

High COVID-19 transmission potential associated with re-opening universities can be mitigated with layered interventions

infectious diseases more details view paper
  • Downloaded 1,282 times
  • Download rankings, all-time:
    • Site-wide: 15,887
    • In infectious diseases: 1,629
  • Year to date:
    • Site-wide: 22,907
  • Since beginning of last month:
    • Site-wide: 29,006

Systematic Mendelian randomization framework elucidates hundreds of genetic loci which may influence disease through changes in DNA methylation levels

genetics more details view paper
  • Downloaded 1,271 times
  • Download rankings, all-time:
    • Site-wide: 16,085
    • In genetics: 765
  • Year to date:
    • Site-wide: 140,270
  • Since beginning of last month:
    • Site-wide: 132,662

Causal epigenome-wide association study identifies CpG sites that influence cardiovascular disease risk

epidemiology more details view paper
  • Downloaded 1,223 times
  • Download rankings, all-time:
    • Site-wide: 17,043
    • In epidemiology: 1,087
  • Year to date:
    • Site-wide: 102,709
  • Since beginning of last month:
    • Site-wide: 121,068

Alcohol consumption and mate choice in UK Biobank: comparing observational and Mendelian randomization estimates

genetics more details view paper
  • Downloaded 1,200 times
  • Download rankings, all-time:
    • Site-wide: 17,507
    • In genetics: 830
  • Year to date:
    • Site-wide: 85,466
  • Since beginning of last month:
    • Site-wide: 83,333

Within-sibship GWAS improve estimates of direct genetic effects

genetics more details view paper
  • Downloaded 1,174 times
  • Download rankings, all-time:
    • Site-wide: 18,079
    • In genetics: 860
  • Year to date:
    • Site-wide: 1,753
  • Since beginning of last month:
    • Site-wide: 2,221

PhenoSpD: an integrated toolkit for phenotypic correlation estimation and multiple testing correction using GWAS summary statistics

bioinformatics more details view paper
  • Downloaded 1,081 times
  • Download rankings, all-time:
    • Site-wide: 20,467
    • In bioinformatics: 2,383
  • Year to date:
    • Site-wide: 70,876
  • Since beginning of last month:
    • Site-wide: 80,989

Education, intelligence and Alzheimer's disease: Evidence from a multivariable two-sample Mendelian randomization study

genetics more details view paper
  • Downloaded 1,060 times
  • Download rankings, all-time:
    • Site-wide: 21,054
    • In genetics: 987
  • Year to date:
    • Site-wide: 99,795
  • Since beginning of last month:
    • Site-wide: 108,529

Causal Inference for Heritable Phenotypic Risk Factors Using Heterogeneous Genetic Instruments

genetics more details view paper
  • Downloaded 1,016 times
  • Download rankings, all-time:
    • Site-wide: 22,430
    • In genetics: 1,048
  • Year to date:
    • Site-wide: 9,527
  • Since beginning of last month:
    • Site-wide: 5,658

Investigating the role of insulin in increased adiposity: Bi-directional Mendelian randomization study

epidemiology more details view paper
  • Downloaded 990 times
  • Download rankings, all-time:
    • Site-wide: 23,234
    • In epidemiology: 1,346
  • Year to date:
    • Site-wide: 69,581
  • Since beginning of last month:
    • Site-wide: 51,750

COVID-19 transmission in a university setting: a rapid review of modelling studies

health policy more details view paper
  • Downloaded 907 times
  • Download rankings, all-time:
    • Site-wide: 26,405
    • In health policy: 73
  • Year to date:
    • Site-wide: 19,748
  • Since beginning of last month:
    • Site-wide: 25,162

Tendency towards being a "Morning person" increases risk of Parkinson's disease: evidence from Mendelian randomisation

epidemiology more details view paper
  • Downloaded 874 times
  • Download rankings, all-time:
    • Site-wide: 27,796
    • In epidemiology: 1,502
  • Year to date:
    • Site-wide: 43,854
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    • Site-wide: 15,200

Genomic and phenomic insights from an atlas of genetic effects on DNA methylation

genetic and genomic medicine more details view paper
  • Downloaded 874 times
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    • Site-wide: 27,799
    • In genetic and genomic medicine: 100
  • Year to date:
    • Site-wide: 8,185
  • Since beginning of last month:
    • Site-wide: 7,634

Identification of loci where DNA methylation potentially mediates genetic risk of type 1 diabetes

genomics more details view paper
  • Downloaded 853 times
  • Download rankings, all-time:
    • Site-wide: 28,763
    • In genomics: 2,603
  • Year to date:
    • Site-wide: 67,463
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    • Site-wide: 80,155

MR-TRYX: A Mendelian randomization framework that exploits horizontal pleiotropy to infer novel causal pathways

bioinformatics more details view paper
  • Downloaded 814 times
  • Download rankings, all-time:
    • Site-wide: 30,727
    • In bioinformatics: 3,454
  • Year to date:
    • Site-wide: 69,754
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    • Site-wide: 45,652

The Causal Effect Of Educational Attainment On Alzheimer's Disease: A Two-Sample Mendelian Randomization Study

epidemiology more details view paper
  • Downloaded 793 times
  • Download rankings, all-time:
    • Site-wide: 31,875
    • In epidemiology: 1,648
  • Year to date:
    • Site-wide: 89,204
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    • Site-wide: 121,064

The variant call format provides efficient and robust storage of GWAS summary statistics

genetics more details view paper
  • Downloaded 723 times
  • Download rankings, all-time:
    • Site-wide: 36,190
    • In genetics: 1,692
  • Year to date:
    • Site-wide: 23,010
  • Since beginning of last month:
    • Site-wide: 23,549

The MRC IEU OpenGWAS data infrastructure

genetics more details view paper
  • Downloaded 711 times
  • Download rankings, all-time:
    • Site-wide: 37,064
    • In genetics: 1,727
  • Year to date:
    • Site-wide: 9,612
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    • Site-wide: 8,341

Orienting The Causal Relationship Between Imprecisely Measured Traits Using Genetic Instruments

systems biology more details view paper
  • Downloaded 659 times
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    • Site-wide: 40,993
    • In systems biology: 911
  • Year to date:
    • Site-wide: 131,582
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    • Site-wide: 128,717

Using genetic instruments to estimate interactions in Mendelian Randomization studies

epidemiology more details view paper
  • Downloaded 657 times
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    • Site-wide: 41,125
    • In epidemiology: 1,987
  • Year to date:
    • Site-wide: 43,797
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    • Site-wide: 31,592

Appraising the causal relevance of DNA methylation for risk of lung cancer

epidemiology more details view paper
  • Downloaded 656 times
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    • Site-wide: 41,216
    • In epidemiology: 1,989
  • Year to date:
    • Site-wide: 101,755
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    • Site-wide: 98,108

Is disrupted sleep a risk factor for Alzheimers disease? Evidence from a two-sample Mendelian randomization analysis

epidemiology more details view paper
  • Downloaded 585 times
  • Download rankings, all-time:
    • Site-wide: 47,546
    • In epidemiology: 2,218
  • Year to date:
    • Site-wide: 117,176
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    • Site-wide: 128,773

The Parkinsons Disease Mendelian Randomization Research Portal

neuroscience more details view paper
  • Downloaded 516 times
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    • Site-wide: 55,305
    • In neuroscience: 8,074
  • Year to date:
    • Site-wide: 127,027
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    • Site-wide: 136,861

What explains the effect of education on cardiovascular disease? Applying Mendelian randomization to identify the consequences of education inequality

epidemiology more details view paper
  • Downloaded 510 times
  • Download rankings, all-time:
    • Site-wide: 56,098
    • In epidemiology: 2,488
  • Year to date:
    • Site-wide: 133,871
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    • Site-wide: 129,783

Systematic evaluation of the causal relationship between DNA methylation and C-reactive protein

genetics more details view paper
  • Downloaded 503 times
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    • Site-wide: 56,930
    • In genetics: 2,576
  • Year to date:
    • Site-wide: 68,400
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    • Site-wide: 80,691

Prenatal alcohol exposure and facial morphology in a UK cohort

epidemiology more details view paper
  • Downloaded 471 times
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    • Site-wide: 61,195
    • In epidemiology: 2,691
  • Year to date:
    • Site-wide: 78,895
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    • Site-wide: 55,366

Investigating the shared genetics of non-syndromic cleft lip/palate and facial morphology

genetics more details view paper
  • Downloaded 465 times
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    • Site-wide: 62,104
    • In genetics: 2,801
  • Year to date:
    • Site-wide: 135,546
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    • Site-wide: 129,948

Schizophrenia risk and reproductive success: A Mendelian randomization study.

evolutionary biology more details view paper
  • Downloaded 437 times
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    • Site-wide: 66,360
    • In evolutionary biology: 3,550
  • Year to date:
    • Site-wide: 120,686
  • Since beginning of last month:
    • Site-wide: 114,833

Does Neuroticism Cause Depression? A Mendelian Randomization Study

genetics more details view paper
  • Downloaded 424 times
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    • Site-wide: 68,420
    • In genetics: 3,091
  • Year to date:
    • Site-wide: 141,969
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    • Site-wide: 138,199

The role of glycaemic and lipid risk factors in mediating the effect of BMI on coronary heart disease: A two-step, two-sample Mendelian randomization study

epidemiology more details view paper
  • Downloaded 422 times
  • Download rankings, all-time:
    • Site-wide: 68,697
    • In epidemiology: 2,960
  • Year to date:
    • Site-wide: 112,441
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    • Site-wide: 76,307

Assortative mating and within-spouse pair comparisons

genetics more details view paper
  • Downloaded 414 times
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    • Site-wide: 70,121
    • In genetics: 3,149
  • Year to date:
    • Site-wide: 53,279
  • Since beginning of last month:
    • Site-wide: 32,714

The use of negative control outcomes in Mendelian Randomisation to detect potential population stratification or selection bias.

genetics more details view paper
  • Downloaded 411 times
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    • Site-wide: 70,626
    • In genetics: 3,169
  • Year to date:
    • Site-wide: 63,795
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    • Site-wide: 85,532

The effect of plasma lipids and lipid lowering interventions on bone mineral density: a Mendelian randomization study

epidemiology more details view paper
  • Downloaded 374 times
  • Download rankings, all-time:
    • Site-wide: 77,015
    • In epidemiology: 3,254
  • Year to date:
    • Site-wide: 120,468
  • Since beginning of last month:
    • Site-wide: 118,085

Partitioning Phenotypic Variance Due To Parent-Of-Origin Effects Using Genomic Relatedness Matrices

genetics more details view paper
  • Downloaded 372 times
  • Download rankings, all-time:
    • Site-wide: 77,420
    • In genetics: 3,464
  • Year to date:
    • Site-wide: 132,438
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    • Site-wide: 99,224

DNA methylation mediates genetic liability to non-syndromic cleft lip/palate

genetics more details view paper
  • Downloaded 351 times
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    • Site-wide: 81,338
    • In genetics: 3,630
  • Year to date:
    • Site-wide: 126,694
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    • Site-wide: 129,877

Investigating DNA methylation as a potential mediator between pigmentation genes, pigmentary traits and skin cancer

genetics more details view paper
  • Downloaded 311 times
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    • Site-wide: 89,727
    • In genetics: 3,959
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    • Site-wide: 53,343
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    • Site-wide: 62,211

Contacts and behaviours of university students during the COVID-19 pandemic at the start of the 2020/21 academic year

public and global health more details view paper
  • Downloaded 302 times
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    • Site-wide: 91,519
    • In public and global health: 1,095
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    • Site-wide: 20,694
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    • Site-wide: 41,150

University students and staff able to maintain low daily contact numbers during various COVID-19 guideline periods

epidemiology more details view paper
  • Downloaded 299 times
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    • Site-wide: 92,198
    • In epidemiology: 3,834
  • Year to date:
    • Site-wide: 12,448
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    • Site-wide: 26,891

Modelling pooling strategies for SARS-CoV-2 testing in a university setting

infectious diseases more details view paper
  • Downloaded 279 times
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    • Site-wide: 96,873
    • In infectious diseases: 4,014
  • Year to date:
    • Site-wide: 13,818
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    • Site-wide: 43,952

EpiGraphDB: a database and data mining platform for health data science

bioinformatics more details view paper
  • Downloaded 251 times
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    • Site-wide: 103,299
    • In bioinformatics: 8,778
  • Year to date:
    • Site-wide: 105,284
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    • Site-wide: 86,113

The association of DNA methylation with body mass index: distinguishing between predictors and biomarkers

genetics more details view paper
  • Downloaded 197 times
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    • Site-wide: 116,019
    • In genetics: 4,940
  • Year to date:
    • Site-wide: 137,869
  • Since beginning of last month:
    • Site-wide: 112,031

Limits of lockdown: characterising essential contacts during strict physical distancing

epidemiology more details view paper
  • Downloaded 141 times
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    • Site-wide: 128,511
    • In epidemiology: 5,281
  • Year to date:
    • Site-wide: 32,892
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    • Site-wide: 56,000

Exploring the variance in complex traits captured by DNA methylation assays

genetics more details view paper
  • Downloaded 120 times
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    • Site-wide: 132,749
    • In genetics: 5,452
  • Year to date:
    • Site-wide: 114,120
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