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Author: George Davey Smith

Rankings

  • All-time downloads: 209,820 (rank: 229 )
  • Categories:
    • bioinformatics: 2,312 (rank: 5,601 (tie) )
    • cardiovascular medicine: 1,079 (rank: 288 (tie) )
    • epidemiology: 129,342 (rank: 97 )
    • evolutionary biology: 414 (rank: 14,361 (tie) )
    • genetic and genomic medicine: 2,900 (rank: 201 )
    • genetics: 66,282 (rank: 47 )
    • genomics: 3,321 (rank: 6,817 (tie) )
    • health economics: 271 (rank: 359 (tie) )
    • neurology: 299 (rank: 2,450 (tie) )
    • neuroscience: 500 (rank: 39,337 (tie) )
    • ophthalmology: 247 (rank: 360 (tie) )
    • pharmacology and toxicology: 1,045 (rank: 921 (tie) )
    • psychiatry and clinical psychology: 398 (rank: 1,733 (tie) )
    • respiratory medicine: 233 (rank: 1,727 )
    • systems biology: 1,177 (rank: 3,289 (tie) )

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Preprints

Puberty and sex-specific trajectories of systolic blood pressure: a prospective cohort study

epidemiology more details view paper

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An Informatics Consult approach for generating clinical evidence for treatment decisions

health informatics more details view paper

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Selection into shift work is influenced by educational attainment and body mass index: A Mendelian randomization study

epidemiology more details view paper
  • Downloaded 61,419 times
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    • Site-wide: 78
    • In epidemiology: 17
  • Year to date:
    • Site-wide: 75,499
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Collider bias undermines our understanding of COVID-19 disease risk and severity

epidemiology more details view paper
  • Downloaded 11,501 times
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    • Site-wide: 569
    • In epidemiology: 84
  • Year to date:
    • Site-wide: 1,574
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A reference panel of 64,976 haplotypes for genotype imputation

genetics more details view paper
  • Downloaded 4,562 times
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    • Site-wide: 1,971
    • In genetics: 80
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MR-Base: a platform for systematic causal inference across the phenome using billions of genetic associations

epidemiology more details view paper
  • Downloaded 3,919 times
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    • Site-wide: 2,453
    • In epidemiology: 247
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Phenome-wide Mendelian randomization mapping the influence of the plasma proteome on complex diseases

genetics more details view paper
  • Downloaded 3,634 times
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    • Site-wide: 2,730
    • In genetics: 111
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PHESANT: a tool for performing automated phenome scans in UK Biobank

epidemiology more details view paper
  • Downloaded 3,333 times
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    • Site-wide: 3,114
    • In epidemiology: 294
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Automating Mendelian randomization through machine learning to construct a putative causal map of the human phenome

epidemiology more details view paper
  • Downloaded 3,261 times
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    • Site-wide: 3,222
    • In epidemiology: 307
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Collider Scope: When selection bias can substantially influence observed associations

epidemiology more details view paper
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    • In epidemiology: 387
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Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine

genetics more details view paper
  • Downloaded 2,489 times
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    • Site-wide: 4,735
    • In genetics: 230
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    • Site-wide: 81,474
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Genome-wide association study identifies 48 common genetic variants associated with handedness

genetics more details view paper
  • Downloaded 2,476 times
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    • Site-wide: 4,778
    • In genetics: 233
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Mendelian randomization: a premature burial?

genetics more details view paper
  • Downloaded 2,405 times
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    • Site-wide: 5,010
    • In genetics: 241
  • Year to date:
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Why are education, socioeconomic position and intelligence genetically correlated?

genetics more details view paper
  • Downloaded 2,385 times
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    • Site-wide: 5,060
    • In genetics: 245
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Polygenic transmission disequilibrium confirms that common and rare variation act additively to create risk for autism spectrum disorders

genetics more details view paper
  • Downloaded 2,360 times
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    • Site-wide: 5,144
    • In genetics: 249
  • Year to date:
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Effect modification of FADS2 polymorphisms on the association between breastfeeding and intelligence: results from a collaborative meta-analysis

epidemiology more details view paper
  • Downloaded 2,318 times
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    • Site-wide: 5,300
    • In epidemiology: 438
  • Year to date:
    • Site-wide: 90,725
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Within-family studies for Mendelian randomization: avoiding dynastic, assortative mating, and population stratification biases

genetics more details view paper
  • Downloaded 2,070 times
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    • Site-wide: 6,223
    • In genetics: 315
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    • Site-wide: 13,911
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Investigating causal relationships between sleep traits and risk of breast cancer: a Mendelian randomization study

epidemiology more details view paper
  • Downloaded 1,913 times
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    • Site-wide: 6,991
    • In epidemiology: 533
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    • Site-wide: 105,744
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An atlas of polygenic risk score associations to highlight putative causal relationships across the human phenome

genetics more details view paper
  • Downloaded 1,829 times
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    • Site-wide: 7,450
    • In genetics: 370
  • Year to date:
    • Site-wide: 95,250
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Common genetic variants and health outcomes appear geographically structured in the UK Biobank sample: Old concerns returning and their implications.

genetics more details view paper
  • Downloaded 1,820 times
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    • Site-wide: 7,498
    • In genetics: 373
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Genomic analysis of diet composition finds novel loci and associations with health and lifestyle

genetics more details view paper
  • Downloaded 1,719 times
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    • Site-wide: 8,186
    • In genetics: 413
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Improving the accuracy of two-sample summary data Mendelian randomization: moving beyond the NOME assumption

epidemiology more details view paper
  • Downloaded 1,712 times
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    • Site-wide: 8,236
    • In epidemiology: 598
  • Year to date:
    • Site-wide: 29,721
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    • Site-wide: 46,807

Genetic Architecture of Subcortical Brain Structures in Over 40,000 Individuals Worldwide

genetics more details view paper
  • Downloaded 1,693 times
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    • Site-wide: 8,390
    • In genetics: 425
  • Year to date:
    • Site-wide: 88,417
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Genetic Associations with Subjective Well-Being Also Implicate Depression and Neuroticism

genetics more details view paper
  • Downloaded 1,684 times
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    • Site-wide: 8,477
    • In genetics: 432
  • Year to date:
    • Site-wide: 104,914
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    • Site-wide: 64,040

Genetic risk for autism spectrum disorders and neuropsychiatric variation in the general population

genetics more details view paper
  • Downloaded 1,657 times
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    • Site-wide: 8,690
    • In genetics: 444
  • Year to date:
    • Site-wide: 100,541
  • Since beginning of last month:
    • Site-wide: 98,853

A transcriptome-wide Mendelian randomization study to uncover tissue-dependent regulatory mechanisms across the human phenome

genetics more details view paper
  • Downloaded 1,612 times
  • Download rankings, all-time:
    • Site-wide: 9,070
    • In genetics: 463
  • Year to date:
    • Site-wide: 70,137
  • Since beginning of last month:
    • Site-wide: 118,682

Mendelian randomisation for mediation analysis: current methods and challenges for implementation

genetics more details view paper
  • Downloaded 1,518 times
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    • Site-wide: 9,920
    • In genetics: 503
  • Year to date:
    • Site-wide: 5,683
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    • Site-wide: 6,397

An examination of multivariable Mendelian randomization in the single sample and two-sample summary data settings.

epidemiology more details view paper
  • Downloaded 1,498 times
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    • Site-wide: 10,087
    • In epidemiology: 701
  • Year to date:
    • Site-wide: 33,187
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    • Site-wide: 44,833

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

genetics more details view paper
  • Downloaded 1,392 times
  • Download rankings, all-time:
    • Site-wide: 11,276
    • In genetics: 573
  • Year to date:
    • Site-wide: 76,525
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    • Site-wide: 62,001

The Causal Effects of Education on Health, Mortality, Cognition, Well-being, and Income in the UK Biobank

epidemiology more details view paper
  • Downloaded 1,376 times
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    • Site-wide: 11,474
    • In epidemiology: 758
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    • Site-wide: 70,271
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    • Site-wide: 86,059

Cigarette smoking increases coffee consumption: findings from a Mendelian randomisation analysis

genetics more details view paper
  • Downloaded 1,367 times
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    • Site-wide: 11,597
    • In genetics: 597
  • Year to date:
    • Site-wide: 22,646
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    • Site-wide: 24,427

Do early life non-cognitive skills matter? A systematic review and meta-analysis of early life effects on academic achievement, psychosocial, language and cognitive, and health outcomes

epidemiology more details view paper
  • Downloaded 1,324 times
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    • Site-wide: 12,148
    • In epidemiology: 794
  • Year to date:
    • Site-wide: 98,773
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    • Site-wide: 69,444

The genetic architecture of osteoarthritis: insights from UK Biobank

genetics more details view paper
  • Downloaded 1,306 times
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    • Site-wide: 12,405
    • In genetics: 638
  • Year to date:
    • Site-wide: 116,956
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    • Site-wide: 59,201

Selection bias in instrumental variable analyses

epidemiology more details view paper
  • Downloaded 1,291 times
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    • Site-wide: 12,612
    • In epidemiology: 822
  • Year to date:
    • Site-wide: 24,371
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    • Site-wide: 25,699

Meffil: efficient normalisation and analysis of very large DNA methylation samples

bioinformatics more details view paper
  • Downloaded 1,266 times
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    • Site-wide: 13,004
    • In bioinformatics: 1,634
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    • Site-wide: 64,265

Systematic Mendelian randomization framework elucidates hundreds of genetic loci which may influence disease through changes in DNA methylation levels

genetics more details view paper
  • Downloaded 1,257 times
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    • Site-wide: 13,139
    • In genetics: 682
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    • Site-wide: 109,127

Causal epigenome-wide association study identifies CpG sites that influence cardiovascular disease risk

epidemiology more details view paper
  • Downloaded 1,193 times
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    • Site-wide: 14,220
    • In epidemiology: 879
  • Year to date:
    • Site-wide: 59,452
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    • Site-wide: 118,434

Alcohol consumption and mate choice in UK Biobank: comparing observational and Mendelian randomization estimates

genetics more details view paper
  • Downloaded 1,155 times
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    • Site-wide: 14,907
    • In genetics: 773
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    • Site-wide: 80,064
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    • Site-wide: 48,216

Multi-omics study revealing tissue-dependent putative mechanisms of SARS-CoV-2 drug targets on viral infections and complex diseases

genetic and genomic medicine more details view paper
  • Downloaded 1,116 times
  • Download rankings, all-time:
    • Site-wide: 15,693
    • In genetic and genomic medicine: 43
  • Year to date:
    • Site-wide: 46,361
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    • Site-wide: 18,462

Narrow-sense heritability estimation of complex traits using identity-by-descent information.

genetics more details view paper
  • Downloaded 1,112 times
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    • Site-wide: 15,795
    • In genetics: 818
  • Year to date:
    • Site-wide: 60,937
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    • Site-wide: 69,990

Bayesian network analysis incorporating genetic anchors complements conventional Mendelian randomization approaches for exploratory analysis of causal relationships in complex data

genetics more details view paper
  • Downloaded 1,089 times
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    • Site-wide: 16,321
    • In genetics: 844
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    • Site-wide: 92,768

Body mass index and mortality in UK Biobank: revised estimates using Mendelian randomization

epidemiology more details view paper
  • Downloaded 1,075 times
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    • Site-wide: 16,651
    • In epidemiology: 981
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    • Site-wide: 97,309
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    • Site-wide: 88,861

Sex-associated autosomal DNA methylation differences are wide-spread and stable throughout childhood

epidemiology more details view paper
  • Downloaded 1,050 times
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    • Site-wide: 17,230
    • In epidemiology: 1,014
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    • Site-wide: 23,812
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Mendelian randomization: a novel approach for the prediction of adverse drug events and drug repurposing opportunities

pharmacology and toxicology more details view paper
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    • Site-wide: 17,345
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    • Site-wide: 102,945
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    • Site-wide: 99,200

Education, intelligence and Alzheimer's disease: Evidence from a multivariable two-sample Mendelian randomization study

genetics more details view paper
  • Downloaded 1,026 times
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    • Site-wide: 17,817
    • In genetics: 914
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    • Site-wide: 77,724
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    • Site-wide: 87,858

Detecting and correcting for bias in Mendelian randomization analyses using gene-by-environment interactions

epidemiology more details view paper
  • Downloaded 1,010 times
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    • Site-wide: 18,288
    • In epidemiology: 1,049
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    • Site-wide: 58,601
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    • Site-wide: 60,829

Maternal BMI at the start of pregnancy and offspring epigenome-wide DNA methylation: Findings from the Pregnancy and Childhood Epigenetics (PACE) consortium.

epidemiology more details view paper
  • Downloaded 999 times
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    • Site-wide: 18,589
    • In epidemiology: 1,061
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    • Site-wide: 60,466
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    • Site-wide: 29,876

The effect of education on adult mortality, health, and income: triangulating across genetic and policy reforms

epidemiology more details view paper
  • Downloaded 998 times
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    • Site-wide: 18,622
    • In epidemiology: 1,063
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    • Site-wide: 85,844
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    • Site-wide: 53,561

An epigenome-wide association study of educational attainment (n = 10,767)

genetics more details view paper
  • Downloaded 965 times
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    • Site-wide: 19,527
    • In genetics: 990
  • Year to date:
    • Site-wide: 42,760
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    • Site-wide: 117,701

Robust inference in summary data Mendelian randomisation via the zero modal pleiotropy assumption

epidemiology more details view paper
  • Downloaded 961 times
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    • Site-wide: 19,645
    • In epidemiology: 1,106
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    • Site-wide: 87,482
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    • Site-wide: 95,973

Causal inference in cancer epidemiology: what is the role of Mendelian randomization?

epidemiology more details view paper
  • Downloaded 957 times
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    • Site-wide: 19,741
    • In epidemiology: 1,110
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    • Site-wide: 99,103
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    • Site-wide: 118,384

Investigating the role of insulin in increased adiposity: Bi-directional Mendelian randomization study

epidemiology more details view paper
  • Downloaded 935 times
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    • Site-wide: 20,445
    • In epidemiology: 1,130
  • Year to date:
    • Site-wide: 38,616
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    • Site-wide: 83,129

Can education be personalised using pupils’ genetic data?

genetics more details view paper
  • Downloaded 921 times
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    • Site-wide: 20,875
    • In genetics: 1,049
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    • Site-wide: 83,106
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    • Site-wide: 63,923

Apolipoprotein B underlies the causal relationship of circulating blood lipids with coronary heart disease

cardiovascular medicine more details view paper
  • Downloaded 875 times
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    • Site-wide: 22,529
    • In cardiovascular medicine: 31
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Imprinted loci may be more widespread in humans than previously appreciated and enable limited assignment of parental allelic transmissions in unrelated individuals

genomics more details view paper
  • Downloaded 854 times
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    • Site-wide: 23,306
    • In genomics: 2,294
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Improving the visualisation, interpretation and analysis of two-sample summary data Mendelian randomization via the radial plot and radial regression

epidemiology more details view paper
  • Downloaded 834 times
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    • Site-wide: 24,111
    • In epidemiology: 1,268
  • Year to date:
    • Site-wide: 109,870
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    • Site-wide: 116,909

The causes and consequences of Alzheimer's disease: A Mendelian randomization analysis

genetic and genomic medicine more details view paper
  • Downloaded 790 times
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    • Site-wide: 25,998
    • In genetic and genomic medicine: 66
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    • Site-wide: 7,359
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    • Site-wide: 24,065

Genetic Epidemiology And Mendelian Randomization For Informing Disease Therapeutics: Conceptual And Methodological Challenges

genetics more details view paper
  • Downloaded 782 times
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    • Site-wide: 26,353
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    • Site-wide: 107,550
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    • Site-wide: 115,722

Genetic Association Study of Childhood Aggression across raters, instruments and age

genomics more details view paper
  • Downloaded 772 times
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    • Site-wide: 26,859
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    • Site-wide: 23,663
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MR-TRYX: A Mendelian randomization framework that exploits horizontal pleiotropy to infer novel causal pathways

bioinformatics more details view paper
  • Downloaded 757 times
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    • Site-wide: 27,567
    • In bioinformatics: 3,257
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    • Site-wide: 60,955
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    • Site-wide: 62,428

Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways

genetics more details view paper
  • Downloaded 757 times
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    • Site-wide: 27,598
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The Causal Effect Of Educational Attainment On Alzheimer's Disease: A Two-Sample Mendelian Randomization Study

epidemiology more details view paper
  • Downloaded 751 times
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    • Site-wide: 27,920
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    • Site-wide: 77,964
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Integrating Mendelian randomization and multiple-trait colocalization to uncover cell-specific inflammatory drivers of autoimmune and atopic disease

genetics more details view paper
  • Downloaded 728 times
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    • Site-wide: 29,135
    • In genetics: 1,465
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    • Site-wide: 59,487
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    • Site-wide: 99,310

Examining the genetic influences of educational attainment and the validity of value-added measures of progress

genetics more details view paper
  • Downloaded 727 times
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    • Site-wide: 29,176
    • In genetics: 1,468
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    • Site-wide: 99,589
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Disentangling genetically confounded polygenic associations between Attention-Deficit/Hyperactivity Disorder, literacy and language

genetics more details view paper
  • Downloaded 716 times
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    • Site-wide: 29,782
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    • Site-wide: 112,862

Using genetics to examine a general liability to childhood psychopathology

genetics more details view paper
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    • Site-wide: 30,196
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Educational attainment impacts drinking behaviors and risk for alcohol dependence: results from a two-sample Mendelian randomization study with ~780 000 participants

epidemiology more details view paper
  • Downloaded 704 times
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    • Site-wide: 30,495
    • In epidemiology: 1,509
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    • Site-wide: 36,069

Trans-ethnic genome-wide association study provides insight into effector genes and molecular mechanisms for kidney function and highlights a causal effect on kidney-specific disease aetiologies

genetics more details view paper
  • Downloaded 703 times
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    • Site-wide: 30,528
    • In genetics: 1,545
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    • Site-wide: 88,324

Can the impact of childhood adiposity on disease risk be reversed? A Mendelian randomization study

epidemiology more details view paper
  • Downloaded 702 times
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    • Site-wide: 30,586
    • In epidemiology: 1,514
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    • Site-wide: 71,497
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Causal Inference for Heritable Phenotypic Risk Factors Using Heterogeneous Genetic Instruments

genetics more details view paper
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    • In genetics: 1,579
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Investigating causality between liability to ADHD and substance use, and liability to substance use and ADHD risk, using Mendelian randomization

genetics more details view paper
  • Downloaded 671 times
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    • Site-wide: 32,550
    • In genetics: 1,632
  • Year to date:
    • Site-wide: 55,454
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    • Site-wide: 74,616

Prioritizing putative influential genes in early life cardiovascular disease susceptibility by applying tissue-specific Mendelian randomization

genetics more details view paper
  • Downloaded 667 times
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    • Site-wide: 32,809
    • In genetics: 1,644
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    • Site-wide: 84,154
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The molecular genetics of participation in the Avon Longitudinal Study of Parents and Children

genetics more details view paper
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Distinct Blood DNA Methylation Profiles In Subtypes Of Orofacial Cleft

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Evidence that low socioeconomic position accentuates genetic susceptibility to obesity

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Orienting The Causal Relationship Between Imprecisely Measured Traits Using Genetic Instruments

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Metabolomic consequences of genetic inhibition of PCSK9 compared with statin treatment

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Education and coronary heart disease: a Mendelian randomization study

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Investigating the longitudinal consistency and genetic architecture of non-cognitive skills, and their relation to educational attainment

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Appraising the causal relevance of DNA methylation for risk of lung cancer

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Assessing the causal role of body mass index on cardiovascular health in young adults: Mendelian randomization and recall-by-genotype analyses

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Genetic architecture of early childhood growth phenotypes gives insights into their link with later obesity

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Disentangling causal relationships between inflammatory markers and depression: a bidirectional Mendelian randomization analysis

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Detecting heterogeneity of intervention effects using analysis and meta-analysis of differences in variance between arms of a trial

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Y chromosome and mitochondrial DNA haplogroups across behavioural traits in children from the general population

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Early metabolic features of genetic liability to type 2 diabetes: cohort study with repeated metabolomics across early life

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Genetic predictors of participation in optional components of UK Biobank

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Slope-Hunter: A robust method for index-event bias correction in genome-wide association studies of subsequent traits

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Association of pre-pregnancy body mass index with future offspring metabolic profile: findings from three independent European birth cohorts

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Is disrupted sleep a risk factor for Alzheimers disease? Evidence from a two-sample Mendelian randomization analysis

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Immune-mediated genetic pathways resulting in pulmonary function impairment increase lung cancer susceptibility

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Mendelian randomisation analysis of the effect of educational attainment and cognitive ability on smoking behaviour

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Low-frequency variation in TP53 has large effects on head circumference and intracranial volume

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Metabolic signatures of birth weight in 18288 adolescents and adults

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Conditioning on a collider may induce spurious associations: Do the results of Gale et al. (2017) support a protective effect of neuroticism in population sub-groups?

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Cigarette smoking and personality: Investigating causality using Mendelian randomization

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Investigating causality in associations between education and smoking: A two-sample Mendelian randomization study

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Genomic and phenomic insights from an atlas of genetic effects on DNA methylation

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The Parkinsons Disease Mendelian Randomization Research Portal

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What explains the effect of education on cardiovascular disease? Applying Mendelian randomization to identify the consequences of education inequality

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The median and the mode as robust meta-analysis methods in the presence of small study effects

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Evaluating the effects of alcohol and tobacco use on cardiovascular disease using multivariable Mendelian randomization

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Mendelian Randomization analysis reveals a causal influence of circulating sclerostin levels on bone mineral density and fractures

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Investigating the shared genetics of non-syndromic cleft lip/palate and facial morphology

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A cross-disorder MR-pheWAS of 5 major psychiatric disorders in UK Biobank

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The causal effect of adiposity on hospital costs: Mendelian Randomization analysis of over 300,000 individuals from the UK Biobank

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Systematic evaluation of the causal relationship between DNA methylation and C-reactive protein

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Epigenetic regulation of PAR4-related platelet activation: mechanistic links between environmental exposure and cardiovascular disease

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Genetic liability to schizophrenia is associated with exposure to traumatic events in childhood

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Evaluating causal associations between previously reported risk factors and epithelial ovarian cancer: a Mendelian randomization analysis

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PCSK9 genetic variants, life-long lowering of LDL-cholesterol and cognition: a large-scale Mendelian randomization study

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Association Between Genetically Elevated Levels Of Inflammatory Biomarkers And Risk Of Schizophrenia: A Two-Sample Mendelian Randomisation Study

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The effect of body mass index on smoking behaviour and nicotine metabolism: a Mendelian randomization study

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Schizophrenia risk and reproductive success: A Mendelian randomization study.

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Investigating the combined association of BMI and alcohol consumption on liver disease and biomarkers: a Mendelian randomization study of over 90 000 adults from the Copenhagen General Population Study

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Genetic liability for schizophrenia and childhood psychopathology in the general population

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Is genetic liability to ADHD and ASD causally linked to educational attainment?

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Circulating selenium and prostate cancer risk: a Mendelian randomization analysis

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CETP inhibition and ADCY9 genotype: evidence of a qualitative pharmacogenetic interaction in cardiovascular disease?

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MR-pheWAS with stratification and interaction: Searching for the causal effects of smoking heaviness identified an effect on facial aging

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The association between adiposity and inpatient hospital costs in the UK Biobank cohort

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Examining the effect of smoking on suicidal ideation and attempts: A Mendelian randomisation study

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The MRC IEU OpenGWAS data infrastructure

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Testing the causal effects between subjective wellbeing and physical health using Mendelian randomisation

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Trans-ethnic Mendelian randomization study reveals causal relationships between cardio-metabolic factors and chronic kidney disease

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Identifying novel subtypes of irritability using a developmental genetic approach

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Partitioning Phenotypic Variance Due To Parent-Of-Origin Effects Using Genomic Relatedness Matrices

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Lipoprotein Signatures of Cholesteryl Ester Transfer Protein and HMG-CoA Reductase Inhibition

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The effect of plasma lipids and lipid lowering interventions on bone mineral density: a Mendelian randomization study

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The use of negative control outcomes in Mendelian Randomisation to detect potential population stratification or selection bias.

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A rare SMAD9 mutation identifies the BMP signalling pathway as a potential osteoanabolic target

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DNA methylation mediates genetic liability to non-syndromic cleft lip/palate

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Assortative mating and within-spouse pair comparisons

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Paternal body mass index and offspring DNA methylation: findings from the PACE consortium

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Adiposity, metabolites, and colorectal cancer risk: Mendelian randomization study

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The Multivariate Genome-wide Architecture of Interrelated Literacy, Language and Working Memory Skills Reveals Distinct Etiologies

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Sex differences in cardiometabolic traits at four life stages: cohort study with repeated metabolomics

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Epigenetic biomarkers of ageing are predictive of mortality risk in a longitudinal clinical cohort of individuals diagnosed with oropharyngeal cancer.

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Effects of apolipoprotein B on the lifespan and risks of major disease including type 2 diabetes: a Mendelian randomization analysis using outcomes in first-degree relatives

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Unhealthy Behaviours and Parkinsons Disease: A Mendelian Randomisation Study

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Do maternal intrauterine environmental influences that lower offspring birthweight causally increase offspring cardiometabolic risk factors in later life? A Mendelian randomization study of 45,849 genotyped parent offspring pairs in the HUNT study

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A robust mean and variance test with application to high-dimensional phenotypes

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Proxy gene-by-environment Mendelian randomization study confirms a causal effect of maternal smoking on offspring birthweight, but little evidence of long-term influences on offspring health

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Biomarker de-Mendelization: principles, potentials and limitations of a strategy to improve biomarker prediction by reducing the component of variance explained by genotype

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Estimating the causal effect of genetic liability to prevalent disease on hospital costs using Mendelian Randomization

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Does Smoking Cause Lower Educational Attainment and General Cognitive Ability? Triangulation of causal evidence using multiple study designs

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Evaluation of the causal effect of fibrinogen on incident coronary heart disease via Mendelian randomization

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Mendelian randomization does not support serum calcium in prostate cancer risk

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The relationship between open angle glaucoma, optic disc morphology and Alzheimer's Disease: a Mendelian randomization study

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Developmental changes within the genetic architecture of social communication behaviour: A multivariate study of genetic variance in unrelated individuals

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Educational inequalities in statin treatment for preventing cardiovascular disease: cross-sectional analysis of UK Biobank

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Interaction-based Mendelian randomization with measured and unmeasured gene-by-covariate interactions

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Association between breastfeeding and DNA methylation over the life course: findings from the Avon Longitudinal Study of Parents and Children (ALSPAC)

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Exploring the causal effects of genetic liability to ADHD and Autism on Alzheimer's disease

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Evaluating the direct effects of childhood adiposity on adult systemic metabolism: A multivariable Mendelian randomization analysis

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The effect of smoking on multiple sclerosis: a mendelian randomization study

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Examining the bidirectional association between emotion recognition and ASD symptoms using observational and genetic analyses

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Mendelian randomisation with coarsened exposures

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The role of school enjoyment in the association between externalising and depressive symptoms and academic attainment: findings from a UK prospective cohort study

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Evaluating the effects of cardiometabolic exposures on circulating proteins which may contribute to SARS-CoV-2 severity

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The role of the metabolic profile in mediating the relationship between body mass index and left ventricular mass in adolescents: analysis of a prospective cohort study

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Using human genetics to understand the causes and consequences of circulating cardiac troponin I in the general population

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A phenome-wide multi-directional Mendelian randomization analysis of atrial fibrillation

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Association of genetic liability to smoking initiation with e-cigarette use in young adults.

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Effects of adiposity on the human plasma proteome: Observational and Mendelian randomization estimates

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Examining the possible causal relationship between Lung Function, COPD and Alzheimers Disease. A Mendelian Randomization Study

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Body muscle gain and markers of cardiovascular disease susceptibility in young adulthood: prospective cohort study

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Using genetic variants to evaluate the causal effect of cholesterol lowering on head and neck cancer risk: a Mendelian randomization study

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Interpreting Mendelian randomization estimates of the effects of categorical exposures such as disease status and educational attainment

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Epidemiology and Genetics of Preserved Ratio Impaired SpiroMetry (PRISm): An Analysis of UK Biobank

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Causal effects of circulating cytokine concentrations on risk of Alzheimers disease: A bidirectional two-sample Mendelian randomization study

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Cross-sectional association of blood pressure variability and night-time dipping with cardiac structure in adolescents

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Sex-specific associations of adiposity with cardiometabolic traits: multi-life-stage cohort study with repeat metabolomics

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