Author: Lewis C. Becker

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Preprints

Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program

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Inherited Causes of Clonal Hematopoiesis of Indeterminate Potential in TOPMed Whole Genomes

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  • Site-wide: 4,319
  • In genomics: 478
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  • Site-wide: 7,556

Novel genetic determinants of telomere length from a trans-ethnic analysis of 109,122 whole genome sequences in TOPMed

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  • Site-wide: 12,025
  • In genetics: 585
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Loss-of-function genomic variants with impact on liver-related blood traits highlight potential therapeutic targets for cardiovascular disease

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  • In genomics: 2,831
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Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations

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  • Site-wide: 37,193
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Rare coding variants in 35 genes associate with circulating lipid levels: a multi-ancestry analysis of 170,000 exomes

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  • In genetics: 1,896
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Genome Sequencing Unveils a New Regulatory Landscape of Platelet Reactivity

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Whole genome sequencing association analysis of quantitative red blood cell phenotypes: the NHLBI TOPMed program

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  • In hematology: 33
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Common genetic variation indicates separate etiologies for periventricular and deep white matter hyperintensities

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  • In neuroscience: 9,111
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Evolution of Hominin Polyunsaturated Fatty Acid Metabolism: From Africa to the New World

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  • In evolutionary biology: 3,566
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Evaluation of the causal effect of fibrinogen on incident coronary heart disease via Mendelian randomization

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  • In genetics: 4,142
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Bidirectional Mendelian randomization supports bidirectional causality between telomere length and clonal hematopoiesis of intermediate potential

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  • Site-wide: 108,179
  • In genetic and genomic medicine: 470
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