Rxivist combines preprints from bioRxiv with data from Twitter to help you find the papers being discussed in your field. Currently indexing 57,773 bioRxiv papers from 265,845 authors.

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Preprints

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

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  • In genetics: 11 out of 3,318
• Year to date:
  • Site-wide: 1,967 out of 57,773
• Since beginning of last month:
  • Site-wide: 9,228 out of 57,773

Discovery Of The First Genome-Wide Significant Risk Loci For ADHD

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  • In genetics: 12 out of 3,318
• Year to date:
  • Site-wide: 517 out of 57,773
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  • Site-wide: 1,678 out of 57,773

LD Score Regression Distinguishes Confounding from Polygenicity in Genome-Wide Association Studies

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  • Site-wide: 198 out of 57,773
  • In genomics: 59 out of 4,057
• Year to date:
  • Site-wide: 30,681 out of 57,773
• Since beginning of last month:
  • Site-wide: 15,025 out of 57,773

Partitioning heritability by functional category using GWAS summary statistics

• Downloaded 6,622 times
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  • Site-wide: 215 out of 57,773
  • In genetics: 25 out of 3,318
• Year to date:
  • Site-wide: 2,178 out of 57,773
• Since beginning of last month:
  • Site-wide: 2,866 out of 57,773

Genomewide association study identifies 30 loci associated with bipolar disorder

• Downloaded 5,910 times
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  • Site-wide: 274 out of 57,773
  • In genetics: 30 out of 3,318
• Year to date:
  • Site-wide: 243 out of 57,773
• Since beginning of last month:
  • Site-wide: 429 out of 57,773

Common risk variants identified in autism spectrum disorder

• Downloaded 5,784 times
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  • Site-wide: 288 out of 57,773
  • In genetics: 34 out of 3,318
• Year to date:
  • Site-wide: 680 out of 57,773
• Since beginning of last month:
  • Site-wide: 3,468 out of 57,773

Genetic meta-analysis identifies 9 novel loci and functional pathways for Alzheimers disease risk

• Downloaded 4,539 times
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  • Site-wide: 438 out of 57,773
  • In genetics: 49 out of 3,318
• Year to date:
  • Site-wide: 1,587 out of 57,773
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  • Site-wide: 3,781 out of 57,773

GWAS meta-analysis (N=279,930) identifies new genes and functional links to intelligence

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  • Site-wide: 446 out of 57,773
  • In genetics: 51 out of 3,318
• Year to date:
  • Site-wide: 5,701 out of 57,773
• Since beginning of last month:
  • Site-wide: 9,092 out of 57,773

Regulatory variants explain much more heritability than coding variants across 11 common diseases

• Downloaded 4,228 times
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  • Site-wide: 515 out of 57,773
  • In genetics: 60 out of 3,318
• Year to date:
  • Site-wide: 24,326 out of 57,773
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  • Site-wide: 15,062 out of 57,773

Local genetic effects on gene expression across 44 human tissues

• Downloaded 4,121 times
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  • Site-wide: 542 out of 57,773
  • In genomics: 143 out of 4,057
• Year to date:
  • Site-wide: 31,432 out of 57,773
• Since beginning of last month:
  • Site-wide: 27,107 out of 57,773

Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions.

• Downloaded 3,495 times
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  • Site-wide: 753 out of 57,773
  • In genetics: 74 out of 3,318
• Year to date:
  • Site-wide: 373 out of 57,773
• Since beginning of last month:
  • Site-wide: 2,994 out of 57,773

Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores

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  • Site-wide: 907 out of 57,773
  • In bioinformatics: 181 out of 5,897
• Year to date:
  • Site-wide: 23,151 out of 57,773
• Since beginning of last month:
  • Site-wide: 18,879 out of 57,773

Haplotypes of common SNPs can explain missing heritability of complex diseases

• Downloaded 2,883 times
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  • Site-wide: 1,073 out of 57,773
  • In genetics: 102 out of 3,318
• Year to date:
  • Site-wide: 35,170 out of 57,773
• Since beginning of last month:
  • Site-wide: 24,743 out of 57,773

Genome wide meta-analysis identifies genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders.

• Downloaded 2,628 times
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  • Site-wide: 1,277 out of 57,773
  • In genomics: 299 out of 4,057
• Year to date:
  • Site-wide: 170 out of 57,773
• Since beginning of last month:
  • Site-wide: 1,186 out of 57,773

Common schizophrenia alleles are enriched in mutation-intolerant genes and maintained by background selection

• Downloaded 2,295 times
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  • Site-wide: 1,621 out of 57,773
  • In genomics: 367 out of 4,057
• Year to date:
  • Site-wide: 41,131 out of 57,773
• Since beginning of last month:
  • Site-wide: 52,700 out of 57,773

Polygenic transmission disequilibrium confirms that common and rare variation act additively to create risk for autism spectrum disorders

• Downloaded 2,165 times
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  • Site-wide: 1,782 out of 57,773
  • In genetics: 176 out of 3,318
• Year to date:
  • Site-wide: 24,529 out of 57,773
• Since beginning of last month:
  • Site-wide: 31,726 out of 57,773

Genome-Wide Association Study Reveals First Locus for Anorexia Nervosa and Metabolic Correlations

• Downloaded 1,766 times
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  • Site-wide: 2,539 out of 57,773
  • In genomics: 520 out of 4,057
• Year to date:
  • Site-wide: 32,516 out of 57,773
• Since beginning of last month:
  • Site-wide: 24,718 out of 57,773

A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects

• Downloaded 1,592 times
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  • Site-wide: 3,033 out of 57,773
  • In genetics: 275 out of 3,318
• Year to date:
  • Site-wide: 40,807 out of 57,773
• Since beginning of last month:
  • Site-wide: 30,991 out of 57,773

Genome-wide association study results for educational attainment aid in identifying genetic heterogeneity of schizophrenia

• Downloaded 1,573 times
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  • Site-wide: 3,089 out of 57,773
  • In genetics: 278 out of 3,318
• Year to date:
  • Site-wide: 20,717 out of 57,773
• Since beginning of last month:
  • Site-wide: 22,464 out of 57,773

Genetic risk for autism spectrum disorders and neuropsychiatric variation in the general population

• Downloaded 1,512 times
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  • Site-wide: 3,285 out of 57,773
  • In genetics: 295 out of 3,318
• Year to date:
  • Site-wide: 44,388 out of 57,773
• Since beginning of last month:
  • Site-wide: 43,250 out of 57,773

Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes

• Downloaded 1,260 times
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  • Site-wide: 4,444 out of 57,773
  • In genomics: 797 out of 4,057
• Year to date:
  • Site-wide: 16,468 out of 57,773
• Since beginning of last month:
  • Site-wide: 33,632 out of 57,773

Comparative genetic architectures of schizophrenia in East Asian and European populations

• Downloaded 1,216 times
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  • Site-wide: 4,705 out of 57,773
  • In genetics: 393 out of 3,318
• Year to date:
  • Site-wide: 3,133 out of 57,773
• Since beginning of last month:
  • Site-wide: 3,680 out of 57,773

Largest genome-wide association study for PTSD identifies genetic risk loci in European and African ancestries and implicates novel biological pathways

• Downloaded 938 times
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  • Site-wide: 7,222 out of 57,773
  • In genetics: 569 out of 3,318
• Year to date:
  • Site-wide: 2,135 out of 57,773
• Since beginning of last month:
  • Site-wide: 3,031 out of 57,773

Subtle stratification confounds estimates of heritability from rare variants

• Downloaded 929 times
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  • Site-wide: 7,319 out of 57,773
  • In genetics: 581 out of 3,318
• Year to date:
  • Site-wide: 35,287 out of 57,773
• Since beginning of last month:
  • Site-wide: 33,713 out of 57,773

Genome-wide association study of suicide attempt in psychiatric disorders identifies association with major depression polygenic risk scores

• Downloaded 639 times
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  • Site-wide: 12,724 out of 57,773
  • In genetics: 910 out of 3,318
• Year to date:
  • Site-wide: 8,703 out of 57,773
• Since beginning of last month:
  • Site-wide: 24,834 out of 57,773

Genome-wide Association Study of Clinical Features in the Schizophrenia Psychiatric Genomics Consortium: Confirmation of Polygenic Effect on Negative Symptoms

• Downloaded 520 times
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  • Site-wide: 16,754 out of 57,773
  • In genetics: 1,161 out of 3,318
• Year to date:
  • Site-wide: 28,584 out of 57,773
• Since beginning of last month:
  • Site-wide: 33,706 out of 57,773

A method to exploit the structure of genetic ancestry space to enhance case-control studies

• Downloaded 398 times
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  • Site-wide: 22,773 out of 57,773
  • In genomics: 2,500 out of 4,057
• Year to date:
  • Site-wide: 50,574 out of 57,773
• Since beginning of last month:
  • Site-wide: 49,712 out of 57,773

Genomewide Analyses of Psychological Resilience in US Army Soldiers

• Downloaded 354 times
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  • Site-wide: 25,720 out of 57,773
  • In genetics: 1,689 out of 3,318
• Year to date:
  • Site-wide: 6,390 out of 57,773
• Since beginning of last month:
  • Site-wide: 16,369 out of 57,773

Genetic variation in the Major Histocompatibility Complex and association with depression

• Downloaded 270 times
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  • Site-wide: 32,790 out of 57,773
  • In genetics: 2,090 out of 3,318
• Year to date:
  • Site-wide: 24,030 out of 57,773
• Since beginning of last month:
  • Site-wide: 20,576 out of 57,773

RICOPILI: Rapid Imputation for COnsortias PIpeLIne

• Downloaded 255 times
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  • Site-wide: 34,289 out of 57,773
  • In genetics: 2,162 out of 3,318
• Year to date:
  • Site-wide: 10,832 out of 57,773
• Since beginning of last month:
  • Site-wide: 14,425 out of 57,773

Genetic comorbidity between major depression and cardio-metabolic disease, stratified by age at onset of major depression.

• Downloaded 188 times
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  • Site-wide: 41,664 out of 57,773
  • In genetics: 2,553 out of 3,318
• Year to date:
  • Site-wide: 16,491 out of 57,773
• Since beginning of last month:
  • Site-wide: 21,618 out of 57,773