Author: Ole Andreassen

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Preprints

Brain age prediction using fMRI network coupling in youths and associations with psychiatric symptoms

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Adipose tissue distribution from body MRI is associated with cross-sectional and longitudinal brain age in adults

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Evidence for a moderating effect of drinking severity but not HIV status on brain age in heavy episodic drinkers

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Maternal and offspring genetic risk score (GRS) analyses of fetal alcohol exposure and ADHD risk in offspring

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Discovery Of The First Genome-Wide Significant Risk Loci For ADHD

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Expanding Parkinson's disease genetics: novel risk loci, genomic context, causal insights and heritable risk.

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The genetic architecture of the human cerebral cortex

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Common risk variants identified in autism spectrum disorder

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Genomewide association study identifies 30 loci associated with bipolar disorder

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Genetic meta-analysis identifies 9 novel loci and functional pathways for Alzheimers disease risk

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GWAS meta-analysis (N=279,930) identifies new genes and functional links to intelligence

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Genome wide meta-analysis identifies genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders.

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  • Site-wide: 2,136
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Greater male than female variability in regional brain structure across the lifespan

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Psychiatric Genomics: An Update and an Agenda

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Ninety-nine independent genetic loci influencing general cognitive function include genes associated with brain health and structure (N = 280,360)

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Beyond SNP Heritability: Polygenicity and Discoverability of Phenotypes Estimated with a Univariate Gaussian Mixture Model

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  • Site-wide: 3,899
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Genetics of brain age suggest an overlap with common brain disorders

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A global view of pleiotropy and genetic architecture in complex traits

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Genome-wide association study identifies 48 common genetic variants associated with handedness

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Estimating inflation in GWAS summary statistics due to variance distortion from cryptic relatedness

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A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects

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Dynamics of Brain Structure and its Genetic Architecture over the Lifespan

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Largest genome-wide association study for PTSD identifies genetic risk loci in European and African ancestries and implicates novel biological pathways

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  • Site-wide: 9,350
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Genetic Architecture of Subcortical Brain Structures in Over 40,000 Individuals Worldwide

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  • Site-wide: 9,405
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Brain Aging in Major Depressive Disorder: Results from the ENIGMA Major Depressive Disorder working group

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Mapping Cortical Brain Asymmetry in 17,141 Healthy Individuals Worldwide via the ENIGMA Consortium

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  • Site-wide: 89,341

Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes

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  • Site-wide: 11,904
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  • Site-wide: 73,536

Genetic Determinants of Cortical Structure (Thickness, Surface Area and Volumes) among Disease Free Adults in the CHARGE Consortium

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Oxytocin gene networks in the human brain: A gene expression and large-scale fMRI meta-analysis study

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  • Site-wide: 12,165
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Cerebellar grey matter volume is associated with cognitive function and psychopathology in adolescence

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  • Site-wide: 12,613
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The correlation between central and peripheral oxytocin concentrations: a systematic review and meta-analysis

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  • Site-wide: 12,812
  • In physiology: 29
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Bivariate causal mixture model quantifies polygenic overlap between complex traits beyond genetic correlation

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  • Site-wide: 14,951
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Linkage Disequilibrium and Heterozygosity Modulate the Genetic Architecture of Human Complex Phenotypes

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Partitioning the genetic architecture of amyotrophic lateral sclerosis

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Estimating Effect Sizes and Expected Replication Probabilities from GWAS Summary Statistics

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Sex-Dependent Shared and Non-Shared Genetic Architecture Across Mood and Psychotic Disorders

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  • Site-wide: 3,608

Cortical Thickness Trajectories across the Lifespan: Data from 17,075 healthy individuals aged 3-90 years

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  • Site-wide: 22,789

Personalized genetic assessment of age associated Alzheimers disease risk

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  • Site-wide: 21,637
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A genetic risk score to guide age-specific, personalized prostate cancer screening

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  • Site-wide: 22,590
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A genome-wide genetic pleiotropy approach identified shared loci between multiple system atrophy and inflammatory bowel disease

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Genome-wide association study of suicide attempt in psychiatric disorders identifies association with major depression polygenic risk scores

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Phenotypically independent mental health symptom profiles are genetically related

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  • Site-wide: 29,141
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Planar cell polarity pathway and development of the human visual cortex

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Lipid associated polygenic enrichment in Alzheimer's disease

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  • Site-wide: 30,445
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Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways

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The genetic structure of Norway

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White matter microstructure across the adult lifespan: A mixed longitudinal and cross-sectional study using advanced diffusion models and brain-age prediction

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The genetic architecture of human brainstem structures and their involvement in common brain disorders

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Subcortical Volume Trajectories across the Lifespan: Data from 18,605 healthy individuals aged 3-90 years

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Shared Genetic Risk between Eating Disorder- and Substance-Use-Related Phenotypes: Evidence from Genome-Wide Association Studies

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Genetic liability for schizophrenia and childhood psychopathology in the general population

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Genome-wide Association Study of Clinical Features in the Schizophrenia Psychiatric Genomics Consortium: Confirmation of Polygenic Effect on Negative Symptoms

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Large-Scale cognitive GWAS Meta-analysis Reveals Tissue-Specific Neural Expression and Potential Nootopic Drug Targets

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Making the MOSTest of imaging genetics

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Probing brain developmental patterns of myelination and associations with psychopathology in youth using gray/white matter contrast

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Recently evolved human-specific methylated regions are enriched in schizophrenia signals

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Cortico-genetic mapping links individual brain maturity in youths to cognitive and psychiatric traits

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Polygenic hazard scores in preclinical Alzheimer's disease

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How important are parents in the development of child anxiety and depression? A genomic analysis of parent-offspring trios in the Norwegian Mother Father and Child Cohort Study (MoBa)

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Immune-related genetic enrichment in frontotemporal dementia

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Predicting cognitive and mental health traits and their polygenic architecture using large-scale brain connectomics

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Sex-dependent polygenic effects on the clinical progressions of Alzheimer's disease

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Maturation of cortical microstructure and cognitive development in childhood and adolescence: a T1w/T2w ratio MRI study

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Pupillary dilation responses as a midlife indicator of risk for Alzheimer's Disease: Association with Alzheimer's disease polygenic risk

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Genome-wide association analysis of the human thalamus identifies novel genomic loci and reveals genetic overlap with distinct cortical regions and ten brain disorders

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Population-based neuroimaging reveals traces of childbirth in the maternal brain

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The dark side of the mean: brain structural heterogeneity in schizophrenia and its polygenic risk.

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Brain age prediction reveals aberrant brain white matter in schizophrenia and bipolar disorder: A multi-sample diffusion tensor imaging study

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Genetic control of variability in subcortical and intracranial volumes

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Identifying Nootropic Drug Targets via Large-Scale Cognitive GWAS and Transcriptomics

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Association between schizophrenia polygenic score and psychotic symptoms in Alzheimer disease: meta-analysis of 11 cohort studies

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Genetic risk for coronary heart disease alters the influence of Alzheimer's genetic risk on mild cognitive impairment

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Dissecting the shared genetic architecture of suicide attempt, psychiatric disorders and known risk factors

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Thinner cortex is associated with psychosis onset in individuals at Clinical High Risk for Developing Psychosis: An ENIGMA Working Group mega-analysis

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Polygenic hazard score: an enrichment marker for Alzheimer's associated amyloid and tau deposition

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Effects of autozygosity and schizophrenia polygenic risk on cognitive and brain developmental trajectories

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Differences in directed functional brain connectivity related to age, sex and mental health

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Multivariate genome-wide association study identifies 780 unique genetic loci associated with cortical morphology.

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Replicating extensive brain structural heterogeneity in individuals with schizophrenia and bipolar disorder

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Assessing distinct patterns of cognitive aging using tissue-specific brain age prediction based on diffusion tensor imaging and brain morphometry

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Beyond SNP Heritability: Polygenicity and Discoverability of Phenotypes Estimated with a Univariate Gaussian Mixture Model

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Heritable cognitive and psychopathology factors in youth are predicted by brain fronto-temporal white matter pathway

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Analysis of differentially methylated regions in primates and non-primates provides support for the evolutionary hypothesis of schizophrenia

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All-optical electrophysiology in hiPSC-derived neurons with synthetic voltage sensors

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Annotation-Informed Causal Mixture Modeling (AI-MiXeR) reveals phenotype-specific differences in polygenicity and effect size distribution across functional annotation categories

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A genetic hazard score to personalize prostate cancer screening, applied to population data

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CXCR4 involvement in neurodegenerative diseases

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Genome-Wide Association Identifies the First Risk Loci for Psychosis in Alzheimer Disease

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The genetic architecture of human cortical folding

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Sex differences in the relationship between social difficulties and executive dysfunction in children and adolescents with autism spectrum disorder

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Improved prediction of schizophrenia by leveraging genetic overlap with brain morphology

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Quantifying the polygenic architecture of the human cerebral cortex: Extensive genetic overlap between cortical thickness and surface area

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Cross-sectional and longitudinal brain scans reveal accelerated brain aging in multiple sclerosis

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Differences in the presentation and progression of Parkinson's disease by sex

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Testing relationships between multimodal modes of brain structural variation and age, sex and polygenic scores for neuroticism in children and adolescents

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Multimodal imaging improves brain age prediction and reveals distinct abnormalities in patients with psychiatric and neurological disorders

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Population-based body-brain mapping links brain morphology and body composition

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Experience-dependent modulation of the visual evoked potential: testing effect sizes, retention over time, and associations with age in 415 healthy individuals

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Brain age estimation is a sensitive marker of processing speed in the early course of multiple sclerosis

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Sparse Deep Neural Networks on Imaging Genetics for Schizophrenia Case-Control Classification

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The effect of sample size on polygenic hazard models for prostate cancer

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White matter aberrations and age-related trajectories in patients with schizophrenia and bipolar disorder revealed by diffusion tensor imaging

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Impact of second-generation antipsychotics on white matter microstructure in adolescent-onset psychosis

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Age dependence of modern clinical risk groups for localized prostate cancer — a population-based study

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Functional connectivity directionality between large-scale resting-state networks in children and adolescence from the Healthy Brain Network sample

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A human iPSC-astroglia neurodevelopmental model reveals divergent transcriptomic patterns in schizophrenia

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Cannabis use is associated with increased levels of soluble gp130 in schizophrenia but not in bipolar disorder

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Genetic overlap between Alzheimer's disease and depression mapped onto the brain

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Identifying intergenerational risk factors for ADHD symptoms using polygenic scores in the Norwegian Mother, Father and Child Cohort

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Cardiometabolic risk factors associated with brain age and accelerate brain ageing

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Evidence for reduced long-term potentiation-like visual cortical plasticity in schizophrenia and bipolar disorder

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In vivo amygdala nuclei volumes in schizophrenia and bipolar disorders

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Additional SNPs improve the performance of a polygenic hazard score for prostate cancer

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Performance of African-ancestry-specific polygenic hazard score varies according to local ancestry in 8q24

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Gut Microbiota Markers for Antipsychotics Induced Metabolic Disturbance in Drug Naive Patients with First Episode Schizophrenia _ A 24 Weeks Follow-up Study

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Prenatal smoking, alcohol and caffeine exposure and ADHD risk in childhood: parental comparisons and polygenic risk score (PRS) analyses

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