Author: Ole Andreassen

Downloads per author, site-wide

Preprints

Genome-wide association analysis reveals extensive genetic overlap between mood instability and psychiatric disorders but divergent patterns of genetic effects

No download data for this paper yet.

Discovery Of The First Genome-Wide Significant Risk Loci For ADHD

• Downloaded 11,597 times
• Download rankings, all-time:
  • Site-wide: 754
  • In genetics: 18
• Year to date:
  • Site-wide: 3,422
• Since beginning of last month:
  • Site-wide: 4,600

Expanding Parkinson's disease genetics: novel risk loci, genomic context, causal insights and heritable risk.

• Downloaded 11,212 times
• Download rankings, all-time:
  • Site-wide: 787
  • In genetics: 20
• Year to date:
  • Site-wide: 3,400
• Since beginning of last month:
  • Site-wide: 4,801

Common risk variants identified in autism spectrum disorder

• Downloaded 8,452 times
• Download rankings, all-time:
  • Site-wide: 1,139
  • In genetics: 29
• Year to date:
  • Site-wide: 2,477
• Since beginning of last month:
  • Site-wide: 2,338

The genetic architecture of the human cerebral cortex

• Downloaded 8,101 times
• Download rankings, all-time:
  • Site-wide: 1,203
  • In genetics: 32
• Year to date:
  • Site-wide: 18,239
• Since beginning of last month:
  • Site-wide: 38,040

Genomewide association study identifies 30 loci associated with bipolar disorder

• Downloaded 7,408 times
• Download rankings, all-time:
  • Site-wide: 1,348
  • In genetics: 40
• Year to date:
  • Site-wide: 23,918
• Since beginning of last month:
  • Site-wide: 33,022

GWAS meta-analysis (N=279,930) identifies new genes and functional links to intelligence

• Downloaded 5,335 times
• Download rankings, all-time:
  • Site-wide: 2,091
  • In genetics: 69
• Year to date:
  • Site-wide: 20,060
• Since beginning of last month:
  • Site-wide: 23,865

Genetic meta-analysis identifies 9 novel loci and functional pathways for Alzheimers disease risk

• Downloaded 5,247 times
• Download rankings, all-time:
  • Site-wide: 2,138
  • In genetics: 71
• Year to date:
  • Site-wide: 49,502
• Since beginning of last month:
  • Site-wide: 51,120

Genome wide meta-analysis identifies genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders.

• Downloaded 4,869 times
• Download rankings, all-time:
  • Site-wide: 2,392
  • In genomics: 237
• Year to date:
  • Site-wide: 18,909
• Since beginning of last month:
  • Site-wide: 23,026

Greater male than female variability in regional brain structure across the lifespan

• Downloaded 3,692 times
• Download rankings, all-time:
  • Site-wide: 3,525
  • In neuroscience: 266
• Year to date:
  • Site-wide: 25,170
• Since beginning of last month:
  • Site-wide: 51,909

Psychiatric Genomics: An Update and an Agenda

• Downloaded 3,414 times
• Download rankings, all-time:
  • Site-wide: 3,919
  • In genetics: 146
• Year to date:
  • Site-wide: 62,314
• Since beginning of last month:
  • Site-wide: 50,710

Ninety-nine independent genetic loci influencing general cognitive function include genes associated with brain health and structure (N = 280,360)

• Downloaded 3,321 times
• Download rankings, all-time:
  • Site-wide: 4,083
  • In genetics: 155
• Year to date:
  • Site-wide: 45,878
• Since beginning of last month:
  • Site-wide: 50,903

Beyond SNP Heritability: Polygenicity and Discoverability of Phenotypes Estimated with a Univariate Gaussian Mixture Model

• Downloaded 3,198 times
• Download rankings, all-time:
  • Site-wide: 4,319
  • In genomics: 452
• Year to date:
  • Site-wide: 32,747
• Since beginning of last month:
  • Site-wide: 30,053

A global view of pleiotropy and genetic architecture in complex traits

• Downloaded 2,889 times
• Download rankings, all-time:
  • Site-wide: 4,969
  • In genetics: 207
• Year to date:
  • Site-wide: 12,928
• Since beginning of last month:
  • Site-wide: 17,843

Genetics of brain age suggest an overlap with common brain disorders

• Downloaded 2,843 times
• Download rankings, all-time:
  • Site-wide: 5,094
  • In neuroscience: 445
• Year to date:
  • Site-wide: 35,646
• Since beginning of last month:
  • Site-wide: 30,133

Genome-wide association study identifies 48 common genetic variants associated with handedness

• Downloaded 2,660 times
• Download rankings, all-time:
  • Site-wide: 5,598
  • In genetics: 241
• Year to date:
  • Site-wide: 25,658
• Since beginning of last month:
  • Site-wide: 28,062

Estimating inflation in GWAS summary statistics due to variance distortion from cryptic relatedness

• Downloaded 2,090 times
• Download rankings, all-time:
  • Site-wide: 7,984
  • In genomics: 840
• Year to date:
  • Site-wide: 11,808
• Since beginning of last month:
  • Site-wide: 12,367

Dynamics of Brain Structure and its Genetic Architecture over the Lifespan

• Downloaded 1,876 times
• Download rankings, all-time:
  • Site-wide: 9,388
  • In genetics: 414
• Year to date:
  • Site-wide: 18,019
• Since beginning of last month:
  • Site-wide: 29,107

Largest genome-wide association study for PTSD identifies genetic risk loci in European and African ancestries and implicates novel biological pathways

• Downloaded 1,832 times
• Download rankings, all-time:
  • Site-wide: 9,716
  • In genetics: 434
• Year to date:
  • Site-wide: 20,549
• Since beginning of last month:
  • Site-wide: 26,665

A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects

• Downloaded 1,823 times
• Download rankings, all-time:
  • Site-wide: 9,781
  • In genetics: 441
• Year to date:
  • Site-wide: 64,228
• Since beginning of last month:
  • Site-wide: 105,036

Genetic Architecture of Subcortical Brain Structures in Over 40,000 Individuals Worldwide

• Downloaded 1,749 times
• Download rankings, all-time:
  • Site-wide: 10,409
  • In genetics: 470
• Year to date:
  • Site-wide: 86,125
• Since beginning of last month:
  • Site-wide: 73,178

Brain Aging in Major Depressive Disorder: Results from the ENIGMA Major Depressive Disorder working group

• Downloaded 1,524 times
• Download rankings, all-time:
  • Site-wide: 12,686
  • In neuroscience: 1,386
• Year to date:
  • Site-wide: 70,361
• Since beginning of last month:
  • Site-wide: 105,560

Genetic Determinants of Cortical Structure (Thickness, Surface Area and Volumes) among Disease Free Adults in the CHARGE Consortium

• Downloaded 1,506 times
• Download rankings, all-time:
  • Site-wide: 12,897
  • In genetics: 593
• Year to date:
  • Site-wide: 38,037
• Since beginning of last month:
  • Site-wide: 67,795

The correlation between central and peripheral oxytocin concentrations: a systematic review and meta-analysis

• Downloaded 1,501 times
• Download rankings, all-time:
  • Site-wide: 12,965
  • In physiology: 27
• Year to date:
  • Site-wide: 27,965
• Since beginning of last month:
  • Site-wide: 31,317

Oxytocin gene networks in the human brain: A gene expression and large-scale fMRI meta-analysis study

• Downloaded 1,491 times
• Download rankings, all-time:
  • Site-wide: 13,124
  • In neuroscience: 1,439
• Year to date:
  • Site-wide: 58,113
• Since beginning of last month:
  • Site-wide: 39,831

Mapping Cortical Brain Asymmetry in 17,141 Healthy Individuals Worldwide via the ENIGMA Consortium

• Downloaded 1,487 times
• Download rankings, all-time:
  • Site-wide: 13,179
  • In neuroscience: 1,448
• Year to date:
  • Site-wide: 103,486
• Since beginning of last month:
  • Site-wide: 94,728

Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes

• Downloaded 1,476 times
• Download rankings, all-time:
  • Site-wide: 13,318
  • In genomics: 1,379
• Year to date:
  • Site-wide: 96,509
• Since beginning of last month:
  • Site-wide: 106,026

Cerebellar grey matter volume is associated with cognitive function and psychopathology in adolescence

• Downloaded 1,439 times
• Download rankings, all-time:
  • Site-wide: 13,895
  • In neuroscience: 1,563
• Year to date:
  • Site-wide: 50,111
• Since beginning of last month:
  • Site-wide: 59,501

Bivariate causal mixture model quantifies polygenic overlap between complex traits beyond genetic correlation

• Downloaded 1,279 times
• Download rankings, all-time:
  • Site-wide: 16,581
  • In genetics: 781
• Year to date:
  • Site-wide: 90,725
• Since beginning of last month:
  • Site-wide: 97,505

Sex-Dependent Shared and Non-Shared Genetic Architecture Across Mood and Psychotic Disorders

• Downloaded 1,274 times
• Download rankings, all-time:
  • Site-wide: 16,672
  • In genetics: 787
• Year to date:
  • Site-wide: 5,430
• Since beginning of last month:
  • Site-wide: 9,215

Linkage Disequilibrium and Heterozygosity Modulate the Genetic Architecture of Human Complex Phenotypes

• Downloaded 1,203 times
• Download rankings, all-time:
  • Site-wide: 18,127
  • In genomics: 1,783
• Year to date:
  • Site-wide: 30,214
• Since beginning of last month:
  • Site-wide: 42,386

Partitioning the genetic architecture of amyotrophic lateral sclerosis

• Downloaded 1,149 times
• Download rankings, all-time:
  • Site-wide: 19,415
  • In genetics: 913
• Year to date:
  • Site-wide: 58,781
• Since beginning of last month:
  • Site-wide: 79,436

Estimating Effect Sizes and Expected Replication Probabilities from GWAS Summary Statistics

• Downloaded 1,129 times
• Download rankings, all-time:
  • Site-wide: 19,928
  • In genetics: 932
• Year to date:
  • Site-wide: 70,217
• Since beginning of last month:
  • Site-wide: 119,533

Cortical Thickness Trajectories across the Lifespan: Data from 17,075 healthy individuals aged 3-90 years

• Downloaded 1,099 times
• Download rankings, all-time:
  • Site-wide: 20,741
  • In neuroscience: 2,577
• Year to date:
  • Site-wide: 26,987
• Since beginning of last month:
  • Site-wide: 36,545

Personalized genetic assessment of age associated Alzheimers disease risk

• Downloaded 988 times
• Download rankings, all-time:
  • Site-wide: 24,242
  • In genetics: 1,126
• Year to date:
  • Site-wide: 107,854
• Since beginning of last month:
  • Site-wide: 113,276

A genetic risk score to guide age-specific, personalized prostate cancer screening

• Downloaded 963 times
• Download rankings, all-time:
  • Site-wide: 25,193
  • In genetics: 1,166
• Year to date:
  • Site-wide: 130,727
• Since beginning of last month:
  • Site-wide: 115,847

A genome-wide genetic pleiotropy approach identified shared loci between multiple system atrophy and inflammatory bowel disease

• Downloaded 954 times
• Download rankings, all-time:
  • Site-wide: 25,522
  • In genetics: 1,187
• Year to date:
  • Site-wide: 77,979
• Since beginning of last month:
  • Site-wide: 69,650

Genetic liability for schizophrenia and childhood psychopathology in the general population

• Downloaded 911 times
• Download rankings, all-time:
  • Site-wide: 27,192
  • In psychiatry and clinical psychology: 96
• Year to date:
  • Site-wide: 6,856
• Since beginning of last month:
  • Site-wide: 14,606

Phenotypically independent mental health symptom profiles are genetically related

• Downloaded 879 times
• Download rankings, all-time:
  • Site-wide: 28,630
  • In psychiatry and clinical psychology: 100
• Year to date:
  • Site-wide: 18,555
• Since beginning of last month:
  • Site-wide: 52,255

Genome-wide association study of suicide attempt in psychiatric disorders identifies association with major depression polygenic risk scores

• Downloaded 866 times
• Download rankings, all-time:
  • Site-wide: 29,262
  • In genetics: 1,358
• Year to date:
  • Site-wide: 92,966
• Since beginning of last month:
  • Site-wide: 79,853

Planar cell polarity pathway and development of the human visual cortex

• Downloaded 807 times
• Download rankings, all-time:
  • Site-wide: 32,267
  • In neuroscience: 4,285
• Year to date:
  • Site-wide: 69,257
• Since beginning of last month:
  • Site-wide: 95,507

The genetic structure of Norway

• Downloaded 798 times
• Download rankings, all-time:
  • Site-wide: 32,734
  • In genetics: 1,525
• Year to date:
  • Site-wide: 42,916
• Since beginning of last month:
  • Site-wide: 100,895

White matter microstructure across the adult lifespan: A mixed longitudinal and cross-sectional study using advanced diffusion models and brain-age prediction

• Downloaded 794 times
• Download rankings, all-time:
  • Site-wide: 33,006
  • In neuroscience: 4,404
• Year to date:
  • Site-wide: 40,909
• Since beginning of last month:
  • Site-wide: 52,257

Lipid associated polygenic enrichment in Alzheimer's disease

• Downloaded 791 times
• Download rankings, all-time:
  • Site-wide: 33,166
  • In genetics: 1,536
• Year to date:
  • Site-wide: 72,665
• Since beginning of last month:
  • Site-wide: 95,596

Shared Genetic Risk between Eating Disorder- and Substance-Use-Related Phenotypes: Evidence from Genome-Wide Association Studies

• Downloaded 771 times
• Download rankings, all-time:
  • Site-wide: 34,361
  • In genetics: 1,584
• Year to date:
  • Site-wide: 23,517
• Since beginning of last month:
  • Site-wide: 74,236

Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways

• Downloaded 770 times
• Download rankings, all-time:
  • Site-wide: 34,402
  • In genetics: 1,585
• Year to date:
  • Site-wide: 128,306
• Since beginning of last month:
  • Site-wide: 122,777

Subcortical Volume Trajectories across the Lifespan: Data from 18,605 healthy individuals aged 3-90 years

• Downloaded 764 times
• Download rankings, all-time:
  • Site-wide: 34,782
  • In neuroscience: 4,695
• Year to date:
  • Site-wide: 47,382
• Since beginning of last month:
  • Site-wide: 88,798

The genetic architecture of human brainstem structures and their involvement in common brain disorders

• Downloaded 763 times
• Download rankings, all-time:
  • Site-wide: 34,858
  • In neuroscience: 4,702
• Year to date:
  • Site-wide: 84,728
• Since beginning of last month:
  • Site-wide: 92,697

Genome-wide Association Study of Clinical Features in the Schizophrenia Psychiatric Genomics Consortium: Confirmation of Polygenic Effect on Negative Symptoms

• Downloaded 725 times
• Download rankings, all-time:
  • Site-wide: 37,394
  • In genetics: 1,716
• Year to date:
  • Site-wide: 105,455
• Since beginning of last month:
  • Site-wide: 116,926

Making the MOSTest of imaging genetics

• Downloaded 722 times
• Download rankings, all-time:
  • Site-wide: 37,656
  • In neuroscience: 5,135
• Year to date:
  • Site-wide: 79,359
• Since beginning of last month:
  • Site-wide: 90,762

Large-Scale cognitive GWAS Meta-analysis Reveals Tissue-Specific Neural Expression and Potential Nootopic Drug Targets

• Downloaded 714 times
• Download rankings, all-time:
  • Site-wide: 38,251
  • In genomics: 3,180
• Year to date:
  • Site-wide: 140,743
• Since beginning of last month:
  • Site-wide: 136,136

Probing brain developmental patterns of myelination and associations with psychopathology in youth using gray/white matter contrast

• Downloaded 677 times
• Download rankings, all-time:
  • Site-wide: 41,007
  • In neuroscience: 5,695
• Year to date:
  • Site-wide: 92,200
• Since beginning of last month:
  • Site-wide: 95,012

Recently evolved human-specific methylated regions are enriched in schizophrenia signals

• Downloaded 666 times
• Download rankings, all-time:
  • Site-wide: 41,920
  • In genomics: 3,407
• Year to date:
  • Site-wide: 121,626
• Since beginning of last month:
  • Site-wide: 132,941

Cortico-genetic mapping links individual brain maturity in youths to cognitive and psychiatric traits

• Downloaded 655 times
• Download rankings, all-time:
  • Site-wide: 42,772
  • In neuroscience: 6,002
• Year to date:
  • Site-wide: 128,589
• Since beginning of last month:
  • Site-wide: 132,693

Predicting cognitive and mental health traits and their polygenic architecture using large-scale brain connectomics

• Downloaded 649 times
• Download rankings, all-time:
  • Site-wide: 43,322
  • In neuroscience: 6,079
• Year to date:
  • Site-wide: 45,384
• Since beginning of last month:
  • Site-wide: 51,704

How important are parents in the development of child anxiety and depression? A genomic analysis of parent-offspring trios in the Norwegian Mother Father and Child Cohort Study (MoBa)

• Downloaded 646 times
• Download rankings, all-time:
  • Site-wide: 43,621
  • In genetic and genomic medicine: 169
• Year to date:
  • Site-wide: 72,190
• Since beginning of last month:
  • Site-wide: 83,852

Polygenic hazard scores in preclinical Alzheimer's disease

• Downloaded 633 times
• Download rankings, all-time:
  • Site-wide: 44,687
  • In genetics: 2,027
• Year to date:
  • Site-wide: 135,382
• Since beginning of last month:
  • Site-wide: 122,813

Immune-related genetic enrichment in frontotemporal dementia

• Downloaded 623 times
• Download rankings, all-time:
  • Site-wide: 45,571
  • In genetics: 2,071
• Year to date:
  • Site-wide: 114,616
• Since beginning of last month:
  • Site-wide: 86,463

Dissecting the shared genetic architecture of suicide attempt, psychiatric disorders and known risk factors

• Downloaded 621 times
• Download rankings, all-time:
  • Site-wide: 45,781
  • In genetic and genomic medicine: 179
• Year to date:
  • Site-wide: 14,519
• Since beginning of last month:
  • Site-wide: 23,637

Thinner cortex is associated with psychosis onset in individuals at Clinical High Risk for Developing Psychosis: An ENIGMA Working Group mega-analysis

• Downloaded 617 times
• Download rankings, all-time:
  • Site-wide: 46,212
  • In psychiatry and clinical psychology: 159
• Year to date:
  • Site-wide: 5,543
• Since beginning of last month:
  • Site-wide: 25,509

Maturation of cortical microstructure and cognitive development in childhood and adolescence: a T1w/T2w ratio MRI study

• Downloaded 616 times
• Download rankings, all-time:
  • Site-wide: 46,292
  • In neuroscience: 6,562
• Year to date:
  • Site-wide: 68,145
• Since beginning of last month:
  • Site-wide: 45,151

Genome-wide association analysis of the human thalamus identifies novel genomic loci and reveals genetic overlap with distinct cortical regions and ten brain disorders

• Downloaded 614 times
• Download rankings, all-time:
  • Site-wide: 46,501
  • In genetic and genomic medicine: 181
• Year to date:
  • Site-wide: 45,851
• Since beginning of last month:
  • Site-wide: 46,916

Pupillary dilation responses as a midlife indicator of risk for Alzheimer's Disease: Association with Alzheimer's disease polygenic risk

• Downloaded 601 times
• Download rankings, all-time:
  • Site-wide: 47,638
  • In genetics: 2,140
• Year to date:
  • Site-wide: 86,416
• Since beginning of last month:
  • Site-wide: 80,193

Sex-dependent polygenic effects on the clinical progressions of Alzheimer's disease

• Downloaded 596 times
• Download rankings, all-time:
  • Site-wide: 48,136
  • In genetics: 2,167
• Year to date:
  • Site-wide: 100,342
• Since beginning of last month:
  • Site-wide: 98,629

Identifying Nootropic Drug Targets via Large-Scale Cognitive GWAS and Transcriptomics

• Downloaded 589 times
• Download rankings, all-time:
  • Site-wide: 48,892
  • In genomics: 3,797
• Year to date:
  • Site-wide: 51,117
• Since beginning of last month:
  • Site-wide: 63,828

Population-based neuroimaging reveals traces of childbirth in the maternal brain

• Downloaded 554 times
• Download rankings, all-time:
  • Site-wide: 52,759
  • In neuroscience: 7,624
• Year to date:
  • Site-wide: 123,892
• Since beginning of last month:
  • Site-wide: 134,678

Brain age prediction reveals aberrant brain white matter in schizophrenia and bipolar disorder: A multi-sample diffusion tensor imaging study

• Downloaded 553 times
• Download rankings, all-time:
  • Site-wide: 52,917
  • In neuroscience: 7,647
• Year to date:
  • Site-wide: 86,075
• Since beginning of last month:
  • Site-wide: 111,843

The dark side of the mean: brain structural heterogeneity in schizophrenia and its polygenic risk.

• Downloaded 535 times
• Download rankings, all-time:
  • Site-wide: 55,002
  • In neuroscience: 7,978
• Year to date:
  • Site-wide: 130,283
• Since beginning of last month:
  • Site-wide: 144,358

Genetic risk for coronary heart disease alters the influence of Alzheimer's genetic risk on mild cognitive impairment

• Downloaded 535 times
• Download rankings, all-time:
  • Site-wide: 55,049
  • In genomics: 4,159
• Year to date:
  • Site-wide: 100,225
• Since beginning of last month:
  • Site-wide: 62,942

Genetic control of variability in subcortical and intracranial volumes

• Downloaded 533 times
• Download rankings, all-time:
  • Site-wide: 55,243
  • In neuroscience: 8,019
• Year to date:
  • Site-wide: 117,865
• Since beginning of last month:
  • Site-wide: 132,166

Association between schizophrenia polygenic score and psychotic symptoms in Alzheimer disease: meta-analysis of 11 cohort studies

• Downloaded 517 times
• Download rankings, all-time:
  • Site-wide: 57,325
  • In genomics: 4,267
• Year to date:
  • Site-wide: 122,351
• Since beginning of last month:
  • Site-wide: 123,559

Multivariate genome-wide association study identifies 780 unique genetic loci associated with cortical morphology.

• Downloaded 504 times
• Download rankings, all-time:
  • Site-wide: 58,970
  • In genetics: 2,638
• Year to date:
  • Site-wide: 25,581
• Since beginning of last month:
  • Site-wide: 42,966

Differences in directed functional brain connectivity related to age, sex and mental health

• Downloaded 498 times
• Download rankings, all-time:
  • Site-wide: 59,756
  • In neuroscience: 8,769
• Year to date:
  • Site-wide: 82,007
• Since beginning of last month:
  • Site-wide: 57,101

Polygenic hazard score: an enrichment marker for Alzheimer's associated amyloid and tau deposition

• Downloaded 491 times
• Download rankings, all-time:
  • Site-wide: 60,737
  • In genetics: 2,721
• Year to date:
  • Site-wide: 89,663
• Since beginning of last month:
  • Site-wide: 135,778

All-optical electrophysiology in hiPSC-derived neurons with synthetic voltage sensors

• Downloaded 484 times
• Download rankings, all-time:
  • Site-wide: 61,663
  • In neuroscience: 9,043
• Year to date:
  • Site-wide: 7,913
• Since beginning of last month:
  • Site-wide: 32,622

Replicating extensive brain structural heterogeneity in individuals with schizophrenia and bipolar disorder

• Downloaded 473 times
• Download rankings, all-time:
  • Site-wide: 63,218
  • In psychiatry and clinical psychology: 218
• Year to date:
  • Site-wide: 37,431
• Since beginning of last month:
  • Site-wide: 52,451

Genome-Wide Association Identifies the First Risk Loci for Psychosis in Alzheimer Disease

• Downloaded 466 times
• Download rankings, all-time:
  • Site-wide: 64,176
  • In psychiatry and clinical psychology: 224
• Year to date:
  • Site-wide: 20,367
• Since beginning of last month:
  • Site-wide: 24,097

Effects of autozygosity and schizophrenia polygenic risk on cognitive and brain developmental trajectories

• Downloaded 464 times
• Download rankings, all-time:
  • Site-wide: 64,534
  • In neuroscience: 9,530
• Year to date:
  • Site-wide: 141,900
• Since beginning of last month:
  • Site-wide: 142,863

The genetic architecture of human cortical folding

• Downloaded 455 times
• Download rankings, all-time:
  • Site-wide: 66,030
  • In genomics: 4,674
• Year to date:
  • Site-wide: 8,682
• Since beginning of last month:
  • Site-wide: 14,316

Vaccination history for diphtheria and tetanus is associated with less severe COVID-19

• Downloaded 449 times
• Download rankings, all-time:
  • Site-wide: 66,972
  • In epidemiology: 2,902
• Year to date:
  • Site-wide: 8,866
• Since beginning of last month:
  • Site-wide: 1,008

Assessing distinct patterns of cognitive aging using tissue-specific brain age prediction based on diffusion tensor imaging and brain morphometry

• Downloaded 440 times
• Download rankings, all-time:
  • Site-wide: 68,244
  • In neuroscience: 10,136
• Year to date:
  • Site-wide: 105,479
• Since beginning of last month:
  • Site-wide: 118,099

Beyond SNP Heritability: Polygenicity and Discoverability of Phenotypes Estimated with a Univariate Gaussian Mixture Model

• Downloaded 432 times
• Download rankings, all-time:
  • Site-wide: 69,662
  • In genetics: 3,121
• Year to date:
  • Site-wide: 146,211
• Since beginning of last month:
  • Site-wide: 139,248

Heritable cognitive and psychopathology factors in youth are predicted by brain fronto-temporal white matter pathway

• Downloaded 421 times
• Download rankings, all-time:
  • Site-wide: 71,388
  • In neuroscience: 10,669
• Year to date:
  • Site-wide: 136,887
• Since beginning of last month:
  • Site-wide: 143,500

Improved prediction of schizophrenia by leveraging genetic overlap with brain morphology

• Downloaded 415 times
• Download rankings, all-time:
  • Site-wide: 72,530
  • In psychiatry and clinical psychology: 249
• Year to date:
  • Site-wide: 37,333
• Since beginning of last month:
  • Site-wide: 29,239

Analysis of differentially methylated regions in primates and non-primates provides support for the evolutionary hypothesis of schizophrenia

• Downloaded 400 times
• Download rankings, all-time:
  • Site-wide: 75,033
  • In genomics: 5,072
• Year to date:
  • Site-wide: 139,703
• Since beginning of last month:
  • Site-wide: 136,313

Annotation-Informed Causal Mixture Modeling (AI-MiXeR) reveals phenotype-specific differences in polygenicity and effect size distribution across functional annotation categories

• Downloaded 399 times
• Download rankings, all-time:
  • Site-wide: 75,185
  • In genetics: 3,317
• Year to date:
  • Site-wide: 113,766
• Since beginning of last month:
  • Site-wide: 107,779

A genetic hazard score to personalize prostate cancer screening, applied to population data

• Downloaded 385 times
• Download rankings, all-time:
  • Site-wide: 77,799
  • In genetics: 3,420
• Year to date:
  • Site-wide: 138,525
• Since beginning of last month:
  • Site-wide: 124,351

CXCR4 involvement in neurodegenerative diseases

• Downloaded 377 times
• Download rankings, all-time:
  • Site-wide: 79,227
  • In genetics: 3,498
• Year to date:
  • Site-wide: 137,889
• Since beginning of last month:
  • Site-wide: 127,029

Quantifying the polygenic architecture of the human cerebral cortex: Extensive genetic overlap between cortical thickness and surface area

• Downloaded 365 times
• Download rankings, all-time:
  • Site-wide: 81,528
  • In neuroscience: 12,267
• Year to date:
  • Site-wide: 127,689
• Since beginning of last month:
  • Site-wide: 145,062

Characterization of the genetic architecture of BMI in infancy and early childhood reveals age-specific effects and implicates pathways involved in Mendelian obesity

• Downloaded 364 times
• Download rankings, all-time:
  • Site-wide: 81,611
  • In genetic and genomic medicine: 343
• Year to date:
  • Site-wide: 11,861
• Since beginning of last month:
  • Site-wide: 13,319

Sex differences in the relationship between social difficulties and executive dysfunction in children and adolescents with autism spectrum disorder

• Downloaded 359 times
• Download rankings, all-time:
  • Site-wide: 82,675
  • In neuroscience: 12,468
• Year to date:
  • Site-wide: 140,376
• Since beginning of last month:
  • Site-wide: 142,826

Cross-sectional and longitudinal brain scans reveal accelerated brain aging in multiple sclerosis

• Downloaded 356 times
• Download rankings, all-time:
  • Site-wide: 83,200
  • In neuroscience: 12,545
• Year to date:
  • Site-wide: 140,631
• Since beginning of last month:
  • Site-wide: 122,608

Multimodal imaging improves brain age prediction and reveals distinct abnormalities in patients with psychiatric and neurological disorders

• Downloaded 348 times
• Download rankings, all-time:
  • Site-wide: 84,795
  • In radiology and imaging: 139
• Year to date:
  • Site-wide: 58,463
• Since beginning of last month:
  • Site-wide: 29,189

Differences in the presentation and progression of Parkinson's disease by sex

• Downloaded 333 times
• Download rankings, all-time:
  • Site-wide: 87,987
  • In neurology: 242
• Year to date:
  • Site-wide: 75,453
• Since beginning of last month:
  • Site-wide: 77,002

Testing relationships between multimodal modes of brain structural variation and age, sex and polygenic scores for neuroticism in children and adolescents

• Downloaded 300 times
• Download rankings, all-time:
  • Site-wide: 95,283
  • In neuroscience: 14,479
• Year to date:
  • Site-wide: 142,975
• Since beginning of last month:
  • Site-wide: 129,566

Functional connectivity directionality between large-scale resting-state networks in children and adolescence from the Healthy Brain Network sample

• Downloaded 297 times
• Download rankings, all-time:
  • Site-wide: 96,022
  • In radiology and imaging: 164
• Year to date:
  • Site-wide: 30,116
• Since beginning of last month:
  • Site-wide: 37,659

Population-based body-brain mapping links brain morphology and body composition

• Downloaded 292 times
• Download rankings, all-time:
  • Site-wide: 97,262
  • In neuroscience: 14,754
• Year to date:
  • Site-wide: 109,288
• Since beginning of last month:
  • Site-wide: 130,507

Experience-dependent modulation of the visual evoked potential: testing effect sizes, retention over time, and associations with age in 415 healthy individuals

• Downloaded 280 times
• Download rankings, all-time:
  • Site-wide: 99,908
  • In neuroscience: 15,201
• Year to date:
  • Site-wide: 139,191
• Since beginning of last month:
  • Site-wide: 129,945

Brain age estimation is a sensitive marker of processing speed in the early course of multiple sclerosis

• Downloaded 271 times
• Download rankings, all-time:
  • Site-wide: 101,860
  • In neuroscience: 15,535
• Year to date:
  • Site-wide: 144,889
• Since beginning of last month:
  • Site-wide: 134,701

Sparse Deep Neural Networks on Imaging Genetics for Schizophrenia Case-Control Classification

• Downloaded 264 times
• Download rankings, all-time:
  • Site-wide: 103,571
  • In psychiatry and clinical psychology: 428
• Year to date:
  • Site-wide: 79,378
• Since beginning of last month:
  • Site-wide: 100,837

A human iPSC-astroglia neurodevelopmental model reveals divergent transcriptomic patterns in schizophrenia

• Downloaded 258 times
• Download rankings, all-time:
  • Site-wide: 104,942
  • In neuroscience: 16,062
• Year to date:
  • Site-wide: 38,213
• Since beginning of last month:
  • Site-wide: 109,902

Impact of second-generation antipsychotics on white matter microstructure in adolescent-onset psychosis

• Downloaded 253 times
• Download rankings, all-time:
  • Site-wide: 106,185
  • In neuroscience: 16,224
• Year to date:
  • Site-wide: 122,046
• Since beginning of last month:
  • Site-wide: 99,230

The effect of sample size on polygenic hazard models for prostate cancer

• Downloaded 251 times
• Download rankings, all-time:
  • Site-wide: 106,625
  • In genetics: 4,572
• Year to date:
  • Site-wide: 143,837
• Since beginning of last month:
  • Site-wide: 135,006

Cardiometabolic risk factors associated with brain age and accelerate brain ageing

• Downloaded 249 times
• Download rankings, all-time:
  • Site-wide: 107,201
  • In neurology: 350
• Year to date:
  • Site-wide: 20,149
• Since beginning of last month:
  • Site-wide: 28,360

Adipose tissue distribution from body MRI is associated with cross-sectional and longitudinal brain age in adults

• Downloaded 249 times
• Download rankings, all-time:
  • Site-wide: 107,200
  • In neurology: 351
• Year to date:
  • Site-wide: 20,147
• Since beginning of last month:
  • Site-wide: 20,670

Identifying intergenerational risk factors for ADHD symptoms using polygenic scores in the Norwegian Mother, Father and Child Cohort

• Downloaded 248 times
• Download rankings, all-time:
  • Site-wide: 107,523
  • In psychiatry and clinical psychology: 456
• Year to date:
  • Site-wide: 20,312
• Since beginning of last month:
  • Site-wide: 28,339

White matter aberrations and age-related trajectories in patients with schizophrenia and bipolar disorder revealed by diffusion tensor imaging

• Downloaded 243 times
• Download rankings, all-time:
  • Site-wide: 108,706
  • In neuroscience: 16,602
• Year to date:
  • Site-wide: 137,934
• Since beginning of last month:
  • Site-wide: 131,632

Age dependence of modern clinical risk groups for localized prostate cancer — a population-based study

• Downloaded 239 times
• Download rankings, all-time:
  • Site-wide: 109,504
  • In epidemiology: 4,575
• Year to date:
  • Site-wide: 111,926
• Since beginning of last month:
  • Site-wide: 103,976

Characterization of Age and Polarity at Onset in Bipolar Disorder

• Downloaded 224 times
• Download rankings, all-time:
  • Site-wide: 113,356
  • In psychiatry and clinical psychology: 491
• Year to date:
  • Site-wide: 23,195
• Since beginning of last month:
  • Site-wide: 19,819

Genetic overlap between multivariate measures of human functional brain connectivity and psychiatric disorders

• Downloaded 219 times
• Download rankings, all-time:
  • Site-wide: 114,564
  • In genetic and genomic medicine: 580
• Year to date:
  • Site-wide: 23,900
• Since beginning of last month:
  • Site-wide: 2,818

Genetic overlap between Alzheimer's disease and depression mapped onto the brain

• Downloaded 214 times
• Download rankings, all-time:
  • Site-wide: 115,714
  • In genetic and genomic medicine: 589
• Year to date:
  • Site-wide: 24,602
• Since beginning of last month:
  • Site-wide: 72,299

Federated Multi-Site Normative Modeling using Hierarchical Bayesian Regression

• Downloaded 203 times
• Download rankings, all-time:
  • Site-wide: 118,600
  • In bioinformatics: 9,681
• Year to date:
  • Site-wide: 26,335
• Since beginning of last month:
  • Site-wide: 4,881

Cannabis use is associated with increased levels of soluble gp130 in schizophrenia but not in bipolar disorder

• Downloaded 191 times
• Download rankings, all-time:
  • Site-wide: 121,361
  • In pharmacology and toxicology: 948
• Year to date:
  • Site-wide: 142,953
• Since beginning of last month:
  • Site-wide: 129,845

Evidence for reduced long-term potentiation-like visual cortical plasticity in schizophrenia and bipolar disorder

• Downloaded 168 times
• Download rankings, all-time:
  • Site-wide: 126,766
  • In neuroscience: 19,231
• Year to date:
  • Site-wide: 89,888
• Since beginning of last month:
  • Site-wide: 90,965

In vivo amygdala nuclei volumes in schizophrenia and bipolar disorders

• Downloaded 163 times
• Download rankings, all-time:
  • Site-wide: 127,915
  • In psychiatry and clinical psychology: 611
• Year to date:
  • Site-wide: 87,076
• Since beginning of last month:
  • Site-wide: 62,379

Brain age prediction using fMRI network coupling in youths and associations with psychiatric symptoms

• Downloaded 163 times
• Download rankings, all-time:
  • Site-wide: 127,916
  • In psychiatry and clinical psychology: 610
• Year to date:
  • Site-wide: 34,131
• Since beginning of last month:
  • Site-wide: 14,028

Additional SNPs improve the performance of a polygenic hazard score for prostate cancer

• Downloaded 146 times
• Download rankings, all-time:
  • Site-wide: 131,594
  • In genetic and genomic medicine: 704
• Year to date:
  • Site-wide: 103,111
• Since beginning of last month:
  • Site-wide: 72,539

Performance of African-ancestry-specific polygenic hazard score varies according to local ancestry in 8q24

• Downloaded 131 times
• Download rankings, all-time:
  • Site-wide: 134,922
  • In genetic and genomic medicine: 733
• Year to date:
  • Site-wide: 43,493
• Since beginning of last month:
  • Site-wide: 50,205

Generalization of Cortical MOSTest Genome-Wide Associations Within and Across Samples

• Downloaded 128 times
• Download rankings, all-time:
  • Site-wide: 135,572
  • In genomics: 7,141
• Year to date:
  • Site-wide: 44,504
• Since beginning of last month:
  • Site-wide: 19,816

Birth Order Differences in Education Are Environmental in Origin

• Downloaded 124 times
• Download rankings, all-time:
  • Site-wide: 136,337
  • In genetics: 5,534
• Year to date:
  • Site-wide: 45,773
• Since beginning of last month:
  • Site-wide: 6,488

Multivariate genome-wide association study on tissue-sensitive diffusion metrics identifies key molecular pathways for axonal growth, synaptogenesis, and astrocyte-mediated neuroinflammation

• Downloaded 124 times
• Download rankings, all-time:
  • Site-wide: 136,425
  • In genetics: 5,536
• Year to date:
  • Site-wide: 45,867
• Since beginning of last month:
  • Site-wide: 6,477

Prenatal smoking, alcohol and caffeine exposure and ADHD risk in childhood: parental comparisons and polygenic risk score (PRS) analyses

• Downloaded 101 times
• Download rankings, all-time:
  • Site-wide: 140,938
  • In epidemiology: 5,770
• Year to date:
  • Site-wide: 56,233
• Since beginning of last month:
  • Site-wide: 62,159

Gut Microbiota Markers for Antipsychotics Induced Metabolic Disturbance in Drug Naive Patients with First Episode Schizophrenia _ A 24 Weeks Follow-up Study

• Downloaded 96 times
• Download rankings, all-time:
  • Site-wide: 141,712
  • In psychiatry and clinical psychology: 807
• Year to date:
  • Site-wide: 58,736
• Since beginning of last month:
  • Site-wide: 62,015

Maternal and offspring genetic risk score (GRS) analyses of fetal alcohol exposure and ADHD risk in offspring

• Downloaded 79 times
• Download rankings, all-time:
  • Site-wide: 144,311
  • In epidemiology: 5,912
• Year to date:
  • Site-wide: 69,077
• Since beginning of last month:
  • Site-wide: 86,316

Evidence for a moderating effect of drinking severity but not HIV status on brain age in heavy episodic drinkers

• Downloaded 65 times
• Download rankings, all-time:
  • Site-wide: 145,914
  • In hiv aids: 155
• Year to date:
  • Site-wide: 81,108
• Since beginning of last month:
  • Site-wide: 52,911

The Genetic Architecture of Amygdala Nuclei

• Downloaded 41 times
• Download rankings, all-time:
  • Site-wide: 147,561
  • In genetic and genomic medicine: 856
• Year to date:
  • Site-wide: 109,436
• Since beginning of last month:
  • Site-wide: 26,043

Spatial frequency discrimination in patients with schizophrenia spectrum and bipolar disorders: Evidence of early visual processing deficits and associations with intellectual abilities

• Downloaded 39 times
• Download rankings, all-time:
  • Site-wide: 147,629
  • In psychiatry and clinical psychology: 906
• Year to date:
  • Site-wide: 111,442
• Since beginning of last month:
  • Site-wide: 27,372