Rxivist combines preprints from bioRxiv with data from Twitter to help you find the papers being discussed in your field. Currently indexing 63,093 bioRxiv papers from 279,869 authors.

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Preprints

Genome-wide association study of gastrointestinal disorders reinforces the link between the digestive tract and the nervous system

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Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

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Recovery of trait heritability from whole genome sequence data

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Expanding Parkinson's disease genetics: novel risk loci, genomic context, causal insights and heritable risk.

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New mutations, old statistical challenges

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Genetic Consequences of Social Stratification in Great Britain

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MTAG: Multi-Trait Analysis of GWAS

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Unraveling the polygenic architecture of complex traits using blood eQTL meta-analysis

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Meta-analysis of genome-wide association studies for height and body mass index in ~700,000 individuals of European ancestry

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Commentary on "Limitations of GCTA as a solution to the missing heritability problem"

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Comparison of methods that use whole genome data to estimate the heritability and genetic architecture of complex traits.

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Improved polygenic prediction by Bayesian multiple regression on summary statistics

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  • In genetics: 206 out of 3,582
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Widespread signatures of negative selection in the genetic architecture of human complex traits

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GWAS on family history of Alzheimer's disease

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A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects

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Causal associations between risk factors and common diseases inferred from GWAS summary data

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A resource-efficient tool for mixed model association analysis of large-scale data

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Mixed Model with Correction for Case-Control Ascertainment Increases Association Power

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  • In genetics: 377 out of 3,582
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Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes

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Meta-analysis of genome-wide association studies for body fat distribution in 694,649 individuals of European ancestry

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Imprint of Assortative Mating on the Human Genome

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Equivalence of LD-Score Regression and Individual-Level-Data Methods

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Genotype-by-environment interactions inferred from genetic effects on phenotypic variability in the UK Biobank

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Improved prediction of chronological age from DNA methylation limits it as a biomarker of ageing

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  • In bioinformatics: 1,331 out of 6,276
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OSCA: a tool for omic-data-based complex trait analysis

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  • Site-wide: 24,901 out of 63,093

Narrow-sense heritability estimation of complex traits using identity-by-descent information.

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  • In genetics: 636 out of 3,582
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Genome-wide association study provides new insights into the genetic architecture and pathogenesis of heart failure

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Identification of 55,000 Replicated DNA Methylation QTL

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Parkinson disease age of onset GWAS: defining heritability, genetic loci and a-synuclein mechanisms

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Epigenetic prediction of complex traits and death

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Expectation of the intercept from bivariate LD score regression in the presence of population stratification

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GWAS of epigenetic ageing rates in blood reveals a critical role for TERT

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Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood

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Novel susceptibility loci and genetic regulation mechanisms for type 2 diabetes

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Bayesian reassessment of the epigenetic architecture of complex traits

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Constraints on eQTL fine mapping in the presence of multi-site local regulation of gene expression

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Epigenetic influences on aging: a longitudinal genome-wide methylation study in old Swedish twins

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Conditional GWAS analysis identifies putative disorder-specific SNPs for psychiatric disorders

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Across-cohort QC analyses of genome-wide association study summary statistics from complex traits

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Widespread associations between grey matter structure and the human phenome

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Bayesian analysis of GWAS summary data reveals differential signatures of natural selection across human complex traits and functional genomic categories

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No evidence for social genetic effects or genetic similarity among friends beyond that due to population stratification: a reappraisal of Domingue et al (2018)

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The effect of X-linked dosage compensation on complex trait variation

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Genetic analyses of medication-use and implications for precision medicine

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Genetic and epigenetic architectures of neurological protein biomarkers in the Lothian Birth Cohort 1936

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An epigenome-wide association study of sex-specific chronological ageing

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Epigenetic signatures of starting and stopping smoking

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