Rxivist logo

Author: Peter M. Visscher

Rankings

  • All-time downloads: 158,835 (rank: 889 )
  • Categories:
    • bioinformatics: 2,634 (rank: 6,872 (tie) )
    • genetic and genomic medicine: 6,713 (rank: 324 )
    • genetics: 113,380 (rank: 16 )
    • genomics: 28,014 (rank: 455 )
    • neurology: 1,529 (rank: 1,321 )
    • neuroscience: 1,708 (rank: 18,703 (tie) )

Downloads per author, site-wide

Preprints

Recovery of trait heritability from whole genome sequence data

genetics more details view paper
  • Downloaded 14,586 times
  • Download rankings, all-time:
    • Site-wide: 792
    • In genetics: 14
  • Year to date:
    • Site-wide: 2,571
  • Since beginning of last month:
    • Site-wide: 5,513

Unraveling the polygenic architecture of complex traits using blood eQTL meta-analysis

genomics more details view paper
  • Downloaded 12,580 times
  • Download rankings, all-time:
    • Site-wide: 956
    • In genomics: 54
  • Year to date:
    • Site-wide: 4,229
  • Since beginning of last month:
    • Site-wide: 5,858

Expanding Parkinson's disease genetics: novel risk loci, genomic context, causal insights and heritable risk.

genetics more details view paper
  • Downloaded 12,020 times
  • Download rankings, all-time:
    • Site-wide: 1,016
    • In genetics: 20
  • Year to date:
    • Site-wide: 7,308
  • Since beginning of last month:
    • Site-wide: 4,709

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

genetics more details view paper
  • Downloaded 9,695 times
  • Download rankings, all-time:
    • Site-wide: 1,320
    • In genetics: 26
  • Year to date:
    • Site-wide: 36,946
  • Since beginning of last month:
    • Site-wide: 25,451

Genetic Consequences of Social Stratification in Great Britain

genetics more details view paper
  • Downloaded 8,685 times
  • Download rankings, all-time:
    • Site-wide: 1,525
    • In genetics: 32
  • Year to date:
    • Site-wide: 9,598
  • Since beginning of last month:
    • Site-wide: 11,218

New mutations, old statistical challenges

genetics more details view paper
  • Downloaded 7,293 times
  • Download rankings, all-time:
    • Site-wide: 1,889
    • In genetics: 44
  • Year to date:
    • Site-wide: 117,671
  • Since beginning of last month:
    • Site-wide: 146,556

MTAG: Multi-Trait Analysis of GWAS

genomics more details view paper
  • Downloaded 7,233 times
  • Download rankings, all-time:
    • Site-wide: 1,915
    • In genomics: 132
  • Year to date:
    • Site-wide: 18,894
  • Since beginning of last month:
    • Site-wide: 33,308

Meta-analysis of genome-wide association studies for height and body mass index in ~700,000 individuals of European ancestry

genetics more details view paper
  • Downloaded 7,071 times
  • Download rankings, all-time:
    • Site-wide: 1,983
    • In genetics: 46
  • Year to date:
    • Site-wide: 25,819
  • Since beginning of last month:
    • Site-wide: 38,958

A Saturated Map of Common Genetic Variants Associated with Human Height from 5.4 Million Individuals of Diverse Ancestries

genetics more details view paper
  • Downloaded 4,927 times
  • Download rankings, all-time:
    • Site-wide: 3,222
    • In genetics: 128
  • Year to date:
    • Site-wide: 197
  • Since beginning of last month:
    • Site-wide: 867

A resource-efficient tool for mixed model association analysis of large-scale data

genetics more details view paper
  • Downloaded 3,518 times
  • Download rankings, all-time:
    • Site-wide: 5,166
    • In genetics: 186
  • Year to date:
    • Site-wide: 12,223
  • Since beginning of last month:
    • Site-wide: 9,043

Commentary on "Limitations of GCTA as a solution to the missing heritability problem"

genetics more details view paper
  • Downloaded 3,173 times
  • Download rankings, all-time:
    • Site-wide: 5,998
    • In genetics: 208
  • Year to date:
    • Site-wide: 61,363
  • Since beginning of last month:
    • Site-wide: 25,412

Improved polygenic prediction by Bayesian multiple regression on summary statistics

genetics more details view paper
  • Downloaded 2,975 times
  • Download rankings, all-time:
    • Site-wide: 6,591
    • In genetics: 239
  • Year to date:
    • Site-wide: 61,293
  • Since beginning of last month:
    • Site-wide: 54,284

A comparison of ten polygenic score methods for psychiatric disorders applied across multiple cohorts

genetic and genomic medicine more details view paper
  • Downloaded 2,909 times
  • Download rankings, all-time:
    • Site-wide: 6,797
    • In genetic and genomic medicine: 35
  • Year to date:
    • Site-wide: 8,452
  • Since beginning of last month:
    • Site-wide: 6,508

Comparison of methods that use whole genome data to estimate the heritability and genetic architecture of complex traits.

genetics more details view paper
  • Downloaded 2,740 times
  • Download rankings, all-time:
    • Site-wide: 7,421
    • In genetics: 274
  • Year to date:
    • Site-wide: 142,817
  • Since beginning of last month:
    • Site-wide: 139,953

Widespread signatures of negative selection in the genetic architecture of human complex traits

genetics more details view paper
  • Downloaded 2,467 times
  • Download rankings, all-time:
    • Site-wide: 8,665
    • In genetics: 331
  • Year to date:
    • Site-wide: 108,123
  • Since beginning of last month:
    • Site-wide: 93,486

GWAS on family history of Alzheimer's disease

genetics more details view paper
  • Downloaded 2,093 times
  • Download rankings, all-time:
    • Site-wide: 11,095
    • In genetics: 406
  • Year to date:
    • Site-wide: 133,936
  • Since beginning of last month:
    • Site-wide: 104,542

A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects

genetics more details view paper
  • Downloaded 1,928 times
  • Download rankings, all-time:
    • Site-wide: 12,499
    • In genetics: 470
  • Year to date:
    • Site-wide: 153,544
  • Since beginning of last month:
    • Site-wide: 115,147

Causal associations between risk factors and common diseases inferred from GWAS summary data

genetics more details view paper
  • Downloaded 1,854 times
  • Download rankings, all-time:
    • Site-wide: 13,244
    • In genetics: 499
  • Year to date:
    • Site-wide: 164,787
  • Since beginning of last month:
    • Site-wide: 116,409

Expectation of the intercept from bivariate LD score regression in the presence of population stratification

genetics more details view paper
  • Downloaded 1,808 times
  • Download rankings, all-time:
    • Site-wide: 13,720
    • In genetics: 578
  • Year to date:
    • Site-wide: 29,574
  • Since beginning of last month:
    • Site-wide: 32,075

Equivalence of LD-Score Regression and Individual-Level-Data Methods

genetics more details view paper
  • Downloaded 1,779 times
  • Download rankings, all-time:
    • Site-wide: 14,075
    • In genetics: 570
  • Year to date:
    • Site-wide: 61,371
  • Since beginning of last month:
    • Site-wide: 45,136

Meta-analysis of genome-wide association studies for body fat distribution in 694,649 individuals of European ancestry

genetics more details view paper
  • Downloaded 1,776 times
  • Download rankings, all-time:
    • Site-wide: 14,124
    • In genetics: 551
  • Year to date:
    • Site-wide: 61,453
  • Since beginning of last month:
    • Site-wide: 91,943

Conditional GWAS analysis identifies putative disorder-specific SNPs for psychiatric disorders

genetics more details view paper
  • Downloaded 1,763 times
  • Download rankings, all-time:
    • Site-wide: 14,308
    • In genetics: 564
  • Year to date:
    • Site-wide: 101,866
  • Since beginning of last month:
    • Site-wide: 111,862

Genotype-by-environment interactions inferred from genetic effects on phenotypic variability in the UK Biobank

genetics more details view paper
  • Downloaded 1,659 times
  • Download rankings, all-time:
    • Site-wide: 15,619
    • In genetics: 624
  • Year to date:
    • Site-wide: 104,292
  • Since beginning of last month:
    • Site-wide: 114,865

Genome-wide association study provides new insights into the genetic architecture and pathogenesis of heart failure

genetics more details view paper
  • Downloaded 1,603 times
  • Download rankings, all-time:
    • Site-wide: 16,473
    • In genetics: 648
  • Year to date:
    • Site-wide: 114,559
  • Since beginning of last month:
    • Site-wide: 185,024

Parkinson disease age of onset GWAS: defining heritability, genetic loci and a-synuclein mechanisms

genetics more details view paper
  • Downloaded 1,580 times
  • Download rankings, all-time:
    • Site-wide: 16,862
    • In genetics: 683
  • Year to date:
    • Site-wide: 101,774
  • Since beginning of last month:
    • Site-wide: 71,928

Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes

genomics more details view paper
  • Downloaded 1,560 times
  • Download rankings, all-time:
    • Site-wide: 17,196
    • In genomics: 1,529
  • Year to date:
    • Site-wide: 108,212
  • Since beginning of last month:
    • Site-wide: 112,183

Bayesian analysis of GWAS summary data reveals differential signatures of natural selection across human complex traits and functional genomic categories

genetics more details view paper
  • Downloaded 1,553 times
  • Download rankings, all-time:
    • Site-wide: 17,317
    • In genetics: 697
  • Year to date:
    • Site-wide: 88,923
  • Since beginning of last month:
    • Site-wide: 78,731

Improved prediction of chronological age from DNA methylation limits it as a biomarker of ageing

bioinformatics more details view paper
  • Downloaded 1,502 times
  • Download rankings, all-time:
    • Site-wide: 18,210
    • In bioinformatics: 1,897
  • Year to date:
    • Site-wide: 78,216
  • Since beginning of last month:
    • Site-wide: 113,231

Theoretical and empirical quantification of the accuracy of polygenic scores in ancestry divergent populations

genetics more details view paper
  • Downloaded 1,501 times
  • Download rankings, all-time:
    • Site-wide: 18,214
    • In genetics: 719
  • Year to date:
    • Site-wide: 178,389
  • Since beginning of last month:
    • Site-wide: 186,074

Mixed Model with Correction for Case-Control Ascertainment Increases Association Power

genetics more details view paper
  • Downloaded 1,466 times
  • Download rankings, all-time:
    • Site-wide: 18,890
    • In genetics: 751
  • Year to date:
    • Site-wide: 180,345
  • Since beginning of last month:
    • Site-wide: 146,263

Probabilistic inference of the genetic architecture of functional enrichment of complex traits

genetic and genomic medicine more details view paper
  • Downloaded 1,463 times
  • Download rankings, all-time:
    • Site-wide: 18,955
    • In genetic and genomic medicine: 97
  • Year to date:
    • Site-wide: 41,892
  • Since beginning of last month:
    • Site-wide: 28,280

Genomic and phenomic insights from an atlas of genetic effects on DNA methylation

genetic and genomic medicine more details view paper
  • Downloaded 1,424 times
  • Download rankings, all-time:
    • Site-wide: 19,766
    • In genetic and genomic medicine: 98
  • Year to date:
    • Site-wide: 31,747
  • Since beginning of last month:
    • Site-wide: 58,624

Bayesian reassessment of the epigenetic architecture of complex traits

genomics more details view paper
  • Downloaded 1,382 times
  • Download rankings, all-time:
    • Site-wide: 20,711
    • In genomics: 1,779
  • Year to date:
    • Site-wide: 152,528
  • Since beginning of last month:
    • Site-wide: 139,848

Imprint of Assortative Mating on the Human Genome

genetics more details view paper
  • Downloaded 1,373 times
  • Download rankings, all-time:
    • Site-wide: 20,929
    • In genetics: 836
  • Year to date:
    • Site-wide: 148,877
  • Since beginning of last month:
    • Site-wide: 133,114

Improved analyses of GWAS summary statistics by reducing data heterogeneity and errors

genetics more details view paper
  • Downloaded 1,362 times
  • Download rankings, all-time:
    • Site-wide: 21,171
    • In genetics: 896
  • Year to date:
    • Site-wide: 46,894
  • Since beginning of last month:
    • Site-wide: 57,860

Narrow-sense heritability estimation of complex traits using identity-by-descent information.

genetics more details view paper
  • Downloaded 1,233 times
  • Download rankings, all-time:
    • Site-wide: 24,771
    • In genetics: 974
  • Year to date:
    • Site-wide: 148,750
  • Since beginning of last month:
    • Site-wide: 160,202

OSCA: a tool for omic-data-based complex trait analysis

bioinformatics more details view paper
  • Downloaded 1,192 times
  • Download rankings, all-time:
    • Site-wide: 26,091
    • In bioinformatics: 2,723
  • Year to date:
    • Site-wide: 118,631
  • Since beginning of last month:
    • Site-wide: 93,209

Identification of 55,000 Replicated DNA Methylation QTL

genomics more details view paper
  • Downloaded 1,116 times
  • Download rankings, all-time:
    • Site-wide: 28,830
    • In genomics: 2,357
  • Year to date:
    • Site-wide: 153,708
  • Since beginning of last month:
    • Site-wide: 129,828

Polygenic risk for Alzheimer's disease predicts sleep slow-waves and daytime sleepiness in youth

neurology more details view paper
  • Downloaded 1,097 times
  • Download rankings, all-time:
    • Site-wide: 29,566
    • In neurology: 82
  • Year to date:
    • Site-wide: 61,018
  • Since beginning of last month:
    • Site-wide: 70,959

Epigenetic prediction of complex traits and death

genomics more details view paper
  • Downloaded 1,090 times
  • Download rankings, all-time:
    • Site-wide: 29,883
    • In genomics: 2,437
  • Year to date:
    • Site-wide: 133,497
  • Since beginning of last month:
    • Site-wide: 85,308

Novel susceptibility loci and genetic regulation mechanisms for type 2 diabetes

genetics more details view paper
  • Downloaded 985 times
  • Download rankings, all-time:
    • Site-wide: 34,743
    • In genetics: 1,381
  • Year to date:
    • Site-wide: 99,129
  • Since beginning of last month:
    • Site-wide: 104,565

Epigenetic scores for the circulating proteome as tools for disease prediction

genomics more details view paper
  • Downloaded 984 times
  • Download rankings, all-time:
    • Site-wide: 34,783
    • In genomics: 2,874
  • Year to date:
    • Site-wide: 34,630
  • Since beginning of last month:
    • Site-wide: 58,821

Widespread associations between grey matter structure and the human phenome

neuroscience more details view paper
  • Downloaded 891 times
  • Download rankings, all-time:
    • Site-wide: 40,258
    • In neuroscience: 4,974
  • Year to date:
    • Site-wide: 149,202
  • Since beginning of last month:
    • Site-wide: 131,097

Genome-wide association study of gastrointestinal disorders reinforces the link between the digestive tract and the nervous system

genomics more details view paper
  • Downloaded 889 times
  • Download rankings, all-time:
    • Site-wide: 40,408
    • In genomics: 3,091
  • Year to date:
    • Site-wide: 112,852
  • Since beginning of last month:
    • Site-wide: 84,912

GWAS of epigenetic ageing rates in blood reveals a critical role for TERT

genetics more details view paper
  • Downloaded 888 times
  • Download rankings, all-time:
    • Site-wide: 40,473
    • In genetics: 1,572
  • Year to date:
    • Site-wide: 185,345
  • Since beginning of last month:
    • Site-wide: 187,644

Estimation of non-additive genetic variance in human complex traits from a large sample of unrelated individuals

genetics more details view paper
  • Downloaded 876 times
  • Download rankings, all-time:
    • Site-wide: 41,269
    • In genetics: 1,643
  • Year to date:
    • Site-wide: 121,117
  • Since beginning of last month:
    • Site-wide: 166,062

Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood

genetics more details view paper
  • Downloaded 858 times
  • Download rankings, all-time:
    • Site-wide: 42,613
    • In genetics: 1,661
  • Year to date:
    • Site-wide: 173,873
  • Since beginning of last month:
    • Site-wide: 159,929

Genome-wide analyses of behavioural traits biased by misreports and longitudinal changes

genetic and genomic medicine more details view paper
  • Downloaded 835 times
  • Download rankings, all-time:
    • Site-wide: 44,420
    • In genetic and genomic medicine: 222
  • Year to date:
    • Site-wide: 147,771
  • Since beginning of last month:
    • Site-wide: 126,046

Genome-wide association study identifies 143 loci associated with 25 hydroxyvitamin D concentration.

genetics more details view paper
  • Downloaded 831 times
  • Download rankings, all-time:
    • Site-wide: 44,719
    • In genetics: 1,752
  • Year to date:
    • Site-wide: 152,175
  • Since beginning of last month:
    • Site-wide: 135,972

Quantifying genetic heterogeneity between continental populations for human height and body mass index

genetics more details view paper
  • Downloaded 803 times
  • Download rankings, all-time:
    • Site-wide: 46,939
    • In genetics: 1,816
  • Year to date:
    • Site-wide: 183,467
  • Since beginning of last month:
    • Site-wide: 166,074

Epigenetic influences on aging: a longitudinal genome-wide methylation study in old Swedish twins

genetics more details view paper
  • Downloaded 724 times
  • Download rankings, all-time:
    • Site-wide: 54,511
    • In genetics: 2,095
  • Year to date:
    • Site-wide: 180,432
  • Since beginning of last month:
    • Site-wide: 183,064

Constraints on eQTL fine mapping in the presence of multi-site local regulation of gene expression

genetics more details view paper
  • Downloaded 703 times
  • Download rankings, all-time:
    • Site-wide: 56,818
    • In genetics: 2,163
  • Year to date:
    • Site-wide: 187,869
  • Since beginning of last month:
    • Site-wide: 170,143

Improving GWAS discovery and genomic prediction accuracy in Biobank data

genomics more details view paper
  • Downloaded 702 times
  • Download rankings, all-time:
    • Site-wide: 56,846
    • In genomics: 4,457
  • Year to date:
    • Site-wide: 21,822
  • Since beginning of last month:
    • Site-wide: 23,104

Assortative Mating Biases Marker-based Heritability Estimators

genetics more details view paper
  • Downloaded 701 times
  • Download rankings, all-time:
    • Site-wide: 57,054
    • In genetics: 2,404
  • Year to date:
    • Site-wide: 37,741
  • Since beginning of last month:
    • Site-wide: 34,000

No evidence for social genetic effects or genetic similarity among friends beyond that due to population stratification: a reappraisal of Domingue et al (2018)

genetics more details view paper
  • Downloaded 649 times
  • Download rankings, all-time:
    • Site-wide: 63,381
    • In genetics: 2,430
  • Year to date:
    • Site-wide: 176,095
  • Since beginning of last month:
    • Site-wide: 178,326

Across-cohort QC analyses of genome-wide association study summary statistics from complex traits

genetics more details view paper
  • Downloaded 648 times
  • Download rankings, all-time:
    • Site-wide: 63,560
    • In genetics: 2,444
  • Year to date:
    • Site-wide: 159,559
  • Since beginning of last month:
    • Site-wide: 170,176

Genetic analyses of medication-use and implications for precision medicine

genetics more details view paper
  • Downloaded 640 times
  • Download rankings, all-time:
    • Site-wide: 64,573
    • In genetics: 2,468
  • Year to date:
    • Site-wide: 181,510
  • Since beginning of last month:
    • Site-wide: 141,157

The Australian Parkinson's Genetics Study (APGS) - pilot (N = 1,532)

neurology more details view paper
  • Downloaded 609 times
  • Download rankings, all-time:
    • Site-wide: 68,785
    • In neurology: 291
  • Year to date:
    • Site-wide: 16,030
  • Since beginning of last month:
    • Site-wide: 11,522

The effect of X-linked dosage compensation on complex trait variation

genetics more details view paper
  • Downloaded 608 times
  • Download rankings, all-time:
    • Site-wide: 68,914
    • In genetics: 2,685
  • Year to date:
    • Site-wide: 117,688
  • Since beginning of last month:
    • Site-wide: 114,737

Integrative omics approach to identify the molecular architecture of inflammatory protein levels in healthy older adults

genomics more details view paper
  • Downloaded 561 times
  • Download rankings, all-time:
    • Site-wide: 76,265
    • In genomics: 4,855
  • Year to date:
    • Site-wide: 146,806
  • Since beginning of last month:
    • Site-wide: 178,749

Genetic and epigenetic architectures of neurological protein biomarkers in the Lothian Birth Cohort 1936

neuroscience more details view paper
  • Downloaded 486 times
  • Download rankings, all-time:
    • Site-wide: 90,376
    • In neuroscience: 12,411
  • Year to date:
    • Site-wide: 134,701
  • Since beginning of last month:
    • Site-wide: 163,623

A parsimonious model for mass-univariate vertex-wise analysis

neuroscience more details view paper
  • Downloaded 484 times
  • Download rankings, all-time:
    • Site-wide: 90,796
    • In neuroscience: 16,004
  • Year to date:
    • Site-wide: 36,029
  • Since beginning of last month:
    • Site-wide: 36,008

Creating and validating a DNA methylation-based proxy for Interleukin-6

genetic and genomic medicine more details view paper
  • Downloaded 472 times
  • Download rankings, all-time:
    • Site-wide: 93,216
    • In genetic and genomic medicine: 511
  • Year to date:
    • Site-wide: 74,619
  • Since beginning of last month:
    • Site-wide: 119,411

Rare Genetic Variants Underlie Outlying levels of DNA Methylation and Gene-Expression

genetics more details view paper
  • Downloaded 471 times
  • Download rankings, all-time:
    • Site-wide: 93,546
    • In genetics: 3,556
  • Year to date:
    • Site-wide: 142,178
  • Since beginning of last month:
    • Site-wide: 182,306

An epigenome-wide association study of sex-specific chronological ageing

genomics more details view paper
  • Downloaded 369 times
  • Download rankings, all-time:
    • Site-wide: 118,450
    • In genomics: 6,408
  • Year to date:
    • Site-wide: 179,918
  • Since beginning of last month:
    • Site-wide: 184,093

Epigenetic signatures of starting and stopping smoking

genomics more details view paper
  • Downloaded 330 times
  • Download rankings, all-time:
    • Site-wide: 129,320
    • In genomics: 6,771
  • Year to date:
    • Site-wide: 173,119
  • Since beginning of last month:
    • Site-wide: 146,519

Local CpG density affects the trajectory of age-associated epigenetic changes

genetics more details view paper
  • Downloaded 274 times
  • Download rankings, all-time:
    • Site-wide: 145,901
    • In genetics: 5,514
  • Year to date:
    • Site-wide: 88,278
  • Since beginning of last month:
    • Site-wide: 80,730

Using prior information from humans to prioritize genes and gene-associated variants for complex traits in livestock

genetics more details view paper
  • Downloaded 269 times
  • Download rankings, all-time:
    • Site-wide: 147,328
    • In genetics: 5,370
  • Year to date:
    • Site-wide: 183,277
  • Since beginning of last month:
    • Site-wide: 152,442

Variation in VKORC1 is associated with vascular dementia

genetics more details view paper
  • Downloaded 190 times
  • Download rankings, all-time:
    • Site-wide: 169,106
    • In genetics: 5,981
  • Year to date:
    • Site-wide: 187,246
  • Since beginning of last month:
    • Site-wide: 157,363

Larger cerebral cortex is genetically correlated with greater frontal area and dorsal thickness

neuroscience more details view paper
  • Downloaded 76 times
  • Download rankings, all-time:
    • Site-wide: 188,185
    • In neuroscience: None
  • Year to date:
    • Site-wide: 60,956
  • Since beginning of last month:
    • Site-wide: 12,494

PanLingua

News