Author: Timothy D. Spector

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Preprints

Refining The Accuracy Of Validated Target Identification Through Coding Variant Fine-Mapping In Type 2 Diabetes

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Genetic discovery and translational decision support from exome sequencing of 20,791 type 2 diabetes cases and 24,440 controls from five ancestries

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PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

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Transcriptome Sequencing Reveals Widespread Gene-Gene and Gene-Environment Interactions

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Age-dependent changes in mean and variance of gene expression across tissues in a twin cohort

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Large-Scale Genome-Wide Meta Analysis of Polycystic Ovary Syndrome Suggests Shared Genetic Architecture for Different Diagnosis Criteria.

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HLA alleles associated with risk of ankylosing spondylitis and rheumatoid arthritis influence the gut microbiome

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Unsupervised integration of multimodal dataset identifies novel signatures of health and disease

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Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways

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Quantifying the degree of sharing of genetic and non-genetic causes of gene expression variability across four tissues.

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Tissue-Specific Alteration of Metabolic Pathways Influences Glycemic Regulation

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Novel genetic loci affecting facial shape variation in humans

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Multi-ancestry GWAS of the electrocardiographic PR interval identifies 210 loci underlying cardiac conduction

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Discovering patterns of pleiotropy in genome-wide association studies

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Genome-wide association meta-analysis of PR interval identifies 47 novel loci associated with atrial and atrioventricular electrical activity

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Genome-wide scan identifies novel genetic loci regulating salivary metabolite levels

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Genomic insights into adaptations of TMA-utilizing methanogens to diverse habitats including the human gut

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