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Author: Lei Huang

Rankings

  • All-time downloads: 26,063 (rank: 8,033 (tie) )
  • Categories:
    • bioinformatics: 1,439 (rank: 11,877 (tie) )
    • biophysics: 2,692 (rank: 1,564 )
    • cancer biology: 594 (rank: 18,254 (tie) )
    • epidemiology: 3,167 (rank: 4,554 (tie) )
    • genetics: 1,862 (rank: 10,667 (tie) )
    • genomics: 751 (rank: 30,499 (tie) )
    • immunology: 2,390 (rank: 5,190 )
    • infectious diseases: 3,440 (rank: 12,955 (tie) )
    • molecular biology: 615 (rank: 12,333 (tie) )
    • neuroscience: 7,115 (rank: 2,634 )
    • oncology: 947 (rank: 869 (tie) )
    • plant biology: 1,051 (rank: 4,461 (tie) )

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Preprints

Intelligent Resolution: Integrating Cryo-EM with AI-driven Multi-resolution Simulations to Observe the SARS-CoV-2 Replication-Transcription Machinery in Action

biophysics more details view paper

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Brain-wide single neuron reconstruction reveals morphological diversity in molecularly defined striatal, thalamic, cortical and claustral neuron types

neuroscience more details view paper
  • Downloaded 6,582 times
  • Download rankings, all-time:
    • Site-wide: 1,749
    • In neuroscience: 83
  • Year to date:
    • Site-wide: 1,951
  • Since beginning of last month:
    • Site-wide: 2,809

Epidemiological and clinical features of COVID-19 patients with and without pneumonia in Beijing, China

epidemiology more details view paper
  • Downloaded 3,167 times
  • Download rankings, all-time:
    • Site-wide: 4,809
    • In epidemiology: 463
  • Year to date:
    • Site-wide: 25,303
  • Since beginning of last month:
    • Site-wide: 25,569

Heterologous vaccination strategy for containing COVID-19 pandemic

infectious diseases more details view paper
  • Downloaded 2,809 times
  • Download rankings, all-time:
    • Site-wide: 5,718
    • In infectious diseases: 1,032
  • Year to date:
    • Site-wide: 1,071
  • Since beginning of last month:
    • Site-wide: 1,964

AI-Driven Multiscale Simulations Illuminate Mechanisms of SARS-CoV-2 Spike Dynamics

biophysics more details view paper
  • Downloaded 2,308 times
  • Download rankings, all-time:
    • Site-wide: 7,641
    • In biophysics: 145
  • Year to date:
    • Site-wide: 2,510
  • Since beginning of last month:
    • Site-wide: 10,858

Selective targeting of an oncogenic KRAS mutant allele by CRISPR/Cas9 induces efficient tumor regression

genetics more details view paper
  • Downloaded 957 times
  • Download rankings, all-time:
    • Site-wide: 28,066
    • In genetics: 1,263
  • Year to date:
    • Site-wide: 41,025
  • Since beginning of last month:
    • Site-wide: 52,443

ACE2 and TMPRSS2 expression by clinical, HLA, immune, and microbial correlates across 34 human cancers and matched normal tissues: implications for SARS-COV-2 COVID-19

oncology more details view paper
  • Downloaded 947 times
  • Download rankings, all-time:
    • Site-wide: 28,508
    • In oncology: 40
  • Year to date:
    • Site-wide: 86,183
  • Since beginning of last month:
    • Site-wide: 129,964

Single-cell landscape of immunological responses in COVID-19 patients

immunology more details view paper
  • Downloaded 915 times
  • Download rankings, all-time:
    • Site-wide: 29,925
    • In immunology: 990
  • Year to date:
    • Site-wide: 42,502
  • Since beginning of last month:
    • Site-wide: 33,409

Unsupervised integration of multimodal dataset identifies novel signatures of health and disease

bioinformatics more details view paper
  • Downloaded 915 times
  • Download rankings, all-time:
    • Site-wide: 29,963
    • In bioinformatics: 3,332
  • Year to date:
    • Site-wide: 134,919
  • Since beginning of last month:
    • Site-wide: 120,388

Profound perturbation of the human metabolome by obesity

genetics more details view paper
  • Downloaded 905 times
  • Download rankings, all-time:
    • Site-wide: 30,390
    • In genetics: 1,364
  • Year to date:
    • Site-wide: 136,136
  • Since beginning of last month:
    • Site-wide: 132,407

Bacterial inhibition of CD8+ T-cells mediated cell death promotes neuroinvasion and within-host persistence

immunology more details view paper
  • Downloaded 761 times
  • Download rankings, all-time:
    • Site-wide: 38,879
    • In immunology: 1,242
  • Year to date:
    • Site-wide: 36,776
  • Since beginning of last month:
    • Site-wide: 39,990

Delayed induction of type I and III interferons mediates nasal epithelial cell permissiveness to SARS-CoV-2

immunology more details view paper
  • Downloaded 714 times
  • Download rankings, all-time:
    • Site-wide: 42,458
    • In immunology: 1,344
  • Year to date:
    • Site-wide: 7,028
  • Since beginning of last month:
    • Site-wide: 3,775

Treatment with human umbilical cord-derived mesenchymal stem cells for COVID-19 patients with lung damage: a randomised, double-blind, placebo controlled phase 2 trial

infectious diseases more details view paper
  • Downloaded 631 times
  • Download rankings, all-time:
    • Site-wide: 49,949
    • In infectious diseases: 3,197
  • Year to date:
    • Site-wide: 28,474
  • Since beginning of last month:
    • Site-wide: 21,546

Enhancer-promoter association determines Sox2 transcription regulation in mouse pluripotent cells

molecular biology more details view paper
  • Downloaded 615 times
  • Download rankings, all-time:
    • Site-wide: 51,606
    • In molecular biology: 1,465
  • Year to date:
    • Site-wide: 75,100
  • Since beginning of last month:
    • Site-wide: 101,628

Start from Scratch: Precisely Identify Massive Active Enhancers by Sequencing

genomics more details view paper
  • Downloaded 609 times
  • Download rankings, all-time:
    • Site-wide: 52,277
    • In genomics: 3,959
  • Year to date:
    • Site-wide: 97,591
  • Since beginning of last month:
    • Site-wide: 50,386

Protein arginine methyltransferase 5 promotes metastasis via enhancing EGFR transcription and modulating AKT1 activation by methylation

cancer biology more details view paper
  • Downloaded 594 times
  • Download rankings, all-time:
    • Site-wide: 53,883
    • In cancer biology: 1,534
  • Year to date:
    • Site-wide: 25,863
  • Since beginning of last month:
    • Site-wide: 34,908

Neuroimmune-glial cells interactions elevate the kynurenine metabolic pathway to sustain neuropathic pain

neuroscience more details view paper
  • Downloaded 533 times
  • Download rankings, all-time:
    • Site-wide: 61,539
    • In neuroscience: 8,899
  • Year to date:
    • Site-wide: 10,907
  • Since beginning of last month:
    • Site-wide: 21,466

Structural Organization of a Type III-A CRISPR Effector Subcomplex Determined by X-ray Crystallography and Cryo-EM

biophysics more details view paper
  • Downloaded 384 times
  • Download rankings, all-time:
    • Site-wide: 86,732
    • In biophysics: 3,215
  • Year to date:
    • Site-wide: 147,552
  • Since beginning of last month:
    • Site-wide: 124,585

Arabidopsis Myosin XIK Interacts with the Exocyst Complex to Facilitate Vesicle Tethering during Exocytosis

plant biology more details view paper
  • Downloaded 375 times
  • Download rankings, all-time:
    • Site-wide: 88,522
    • In plant biology: 2,334
  • Year to date:
    • Site-wide: 62,193
  • Since beginning of last month:
    • Site-wide: 97,473

Endosidin20 targets cellulose synthase catalytic domain to inhibit cellulose biosynthesis

plant biology more details view paper
  • Downloaded 355 times
  • Download rankings, all-time:
    • Site-wide: 92,986
    • In plant biology: 2,464
  • Year to date:
    • Site-wide: 138,875
  • Since beginning of last month:
    • Site-wide: 131,005

Addition of Genetics to Quantitative MRI Facilitates Earlier Prediction of Dementia: A Non-invasive Alternative to Amyloid Measures

bioinformatics more details view paper
  • Downloaded 354 times
  • Download rankings, all-time:
    • Site-wide: 93,177
    • In bioinformatics: 8,200
  • Year to date:
    • Site-wide: 123,055
  • Since beginning of last month:
    • Site-wide: 143,044

Endosidin20 is a broad-spectrum cellulose synthesis inhibitor with an herbicidal function

plant biology more details view paper
  • Downloaded 321 times
  • Download rankings, all-time:
    • Site-wide: 100,834
    • In plant biology: 2,689
  • Year to date:
    • Site-wide: 100,774
  • Since beginning of last month:
    • Site-wide: 88,594

DeepMotifSyn: a deep learning approach to synthesize heterodimeric DNA motifs

bioinformatics more details view paper
  • Downloaded 170 times
  • Download rankings, all-time:
    • Site-wide: 138,931
    • In bioinformatics: 10,807
  • Year to date:
    • Site-wide: 51,494
  • Since beginning of last month:
    • Site-wide: 41,605

Induce Pluripotency via Specific distal enhancer-promoter associations

genomics more details view paper
  • Downloaded 142 times
  • Download rankings, all-time:
    • Site-wide: 145,244
    • In genomics: 7,479
  • Year to date:
    • Site-wide: 61,993
  • Since beginning of last month:
    • Site-wide: 116,048

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