Author: Yang Liu

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Preprints

IgY antibodies against Ebola virus possess post-exposure protection and excellent thermostability

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Personalized in-silico drug response prediction based on the genetic landscape of muscle-invasive bladder cancer

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A portable and cost-effective microfluidic system for massively parallel single-cell transcriptome profiling

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Single-cell atlas of a non-human primate reveals new pathogenic mechanisms of COVID-19

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High-Spatial-Resolution Multi-Omics Atlas Sequencing of Mouse Embryos via Deterministic Barcoding in Tissue

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Direct preparation of Cas9 ribonucleoprotein from E. coli for PCR-free seamless DNA assembly

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WRN Helicase is a Synthetic Lethal Target in Microsatellite Unstable Cancers

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Deconvolution of single-cell multi-omics layers reveals regulatory heterogeneity

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Enhancing Intracellular Concentration and Target Engagement of PROTACs with Reversible Covalent Chemistry

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Augmented Reality Powers a Cognitive Prosthesis for the Blind

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Asgard archaea are diverse, ubiquitous, and transcriptionally active microbes

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Learning Structural Motif Representations For Efficient Protein Structure Search

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Deep Genomic Signature for early metastasis prediction in prostate cancer

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Deciphering signaling specificity with interpretable deep neural networks

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RISC: robust integration of single-cell RNA-seq datasets with different extents of cell cluster overlap

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Cyclic-di-GMP is required for corneal infection by Pseudomonas aeruginosa and modulates host immunity

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Evolutionary context-integrated deep sequence modeling for protein engineering

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Generalizing Genetic Risk Scores from Europeans to Hispanics/Latinos

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Single-nucleus RNA-seq identifies Huntington disease astrocyte states

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METABOLIC: A scalable high-throughput metabolic and biogeochemical functional trait profiler based on microbial genomes

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Discovery of the Quiescent Body that Functions as a Biological Timer for Growth Resumption of Non-growing Bacterial Cells

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Recurrently deregulated lncRNAs associated with HCC tumorigenesis and metastasis revealed by genomic, epigenomic and transcriptomic profiling in paired primary tumor and PVTT samples

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Super-resolution imaging reveals the evolution of higher-order chromatin folding in early carcinogenesis

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WindSTORM: Robust online image processing for high-throughput nanoscopy

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Divergence in the face of gene flow in two Charadrius plovers along the Chinese coast

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A chromosome-level genome of black rockfish, Sebastes schlegelii, provides insights into the evolution of live birth

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Spatiotemporal Gene Coexpression and Regulation in Mouse Cardiomyocytes of Early Cardiac Morphogenesis

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The histone chaperone FACT modulates nucleosome structure by tethering its components

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Highly diverse Asgard archaea participate in organic matter degradation in coastal sediments

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Enhanced super-resolution microscopy by extreme value based emitter recovery

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Comparative analyses of 3654 chloroplast genomes unraveled new insights into the evolutionary mechanism of green plants

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Cytotoxicity evaluation of chloroquine and hydroxychloroquine in multiple cell lines and tissues by dynamic imaging system and PBPK model

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Neo-sex chromosomes, genetic diversity and demographic history in the Critically Endangered Raso lark

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Screening of FDA-approved Drugs and Identification of Novel Lassa Virus Entry Inhibitors

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Genome and community-level interaction insights on wide carbon utilizing and element cycling function of Hydrothermarchaeota from hydrothermal sediment

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Molecular basis of P[6] and P[8] major human rotavirus VP8* domain interactions with histo-blood group antigens

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The first set of universal nuclear protein-coding loci markers for avian phylogenetic and population genetic studies

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Demographic histories and genome-wide patterns of divergence in incipient species of shorebirds

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Rice NIN-LIKE PROTEIN 4 is a master regulator of nitrogen use efficiency

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Ectomycorrhizal fungi induce systemic resistance against insects on a non-mycorrhizal plant in a CERK1-dependent manner

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The closed-loop pathways of signaling molecules

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Out of the Qinghai-Tibetan Plateau and get flourishing - the evolution of Neodon voles (Rodentia: Cricetidae) revealed by systematic sampling and low coverage whole genome sequencing

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Co-evolution of Eukaryotic-like Vps4 and ESCRT-III Subunits in the Asgard Archaea

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Regionally divergent drivers of historical diversification in the late Quaternary in a widely distributed generalist species, the common pheasant Phasianus colchicus

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Genome assembly of the common pheasant Phasianus colchicus, a model for speciation and ecological genomics

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Cdc42 is required for lymphatic branching, maturation and valve formation during embryonic development

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High-throughput living-cell protein crosslinking analysis uncovers the physiological relevance of forming the "inserted" state of the ATP synthase ϵ-subunit

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A Na2CO3-responsive chitinase gene from Chinese wildrye improve pathogen resistance and saline-alkali stress tolerance in transgenic tobacco and maize

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Draft genome of the aquatic moss Fontinalis antipyretica (Fontinalaceae, Bryophyta)

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Meta-16S rRNA gene phylogenetic reconstruction reveals astonishing diversity of the cosmopolitan myxobacteria

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The complete plastid genomes of two Fabaceae orphan crops from Africa

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Genetic diversity and evolution of Hantaan virus in China and its neighbors

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Infection risk and extensive parental care govern the molecular evolution of Toll-like receptors in birds.

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Src/FAK complex phosphorylates cardiac myosin binding protein c (cMyBP-C) in vitro and in vivo

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Population genomic analyses of schistosome parasites highlight critical challenges facing end-game elimination efforts

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Silent dissemination of plasmid-borne tigecycline resistance gene tet(X6) in livestock-associated Acinetobacter towneri

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