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Author: Jonathan K. Pritchard

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  • All-time downloads: 84,662 (rank: 204 out of 338,050)
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    • cell biology: 275 (rank: 16,199 (tie) out of 24,213)
    • evolutionary biology: 9,540 (rank: 80 out of 17,741)
    • genetics: 37,741 (rank: 96 out of 32,586)
    • genomics: 32,345 (rank: 198 out of 37,096)
    • molecular biology: 3,858 (rank: 289 (tie) out of 16,885)
    • scientific communication and education: 903 (rank: 662 (tie) out of 2,879)

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Preprints

Detection of human adaptation during the past 2,000 years

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LeafCutter: Annotation-free quantification of RNA splicing

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Variational Inference of Population Structure in Large SNP Datasets

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Reduced signal for polygenic adaptation of height in UK Biobank

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Variable prediction accuracy of polygenic scores within an ancestry group

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Genetics of 38 blood and urine biomarkers in the UK Biobank

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Trans effects on gene expression can drive omnigenic inheritance

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Evolutionary persistence of DNA methylation for millions of years after ancient loss of a de novo methyltransferase

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Landscape of stimulation-responsive chromatin across diverse human immune cells

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WASP: allele-specific software for robust discovery of molecular quantitative trait loci

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Coregulation of tandem duplicate genes slows evolution of subfunctionalization in mammals.

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Thousands of novel translated open reading frames in humans inferred by ribosome footprint profiling

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Batch effects and the effective design of single-cell gene expression studies

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Inferring Relevant Cell Types For Complex Traits Using Single-Cell Gene Expression

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High-resolution mapping of cancer cell networks using co-functional interactions

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Rapid evolution of the human mutation spectrum

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Impact of regulatory variation across human iPSCs and differentiated cells

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Effects of variable mutation rates and epistasis on the distribution of allele frequencies in humans

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Methylation QTLs are associated with coordinated changes in transcription factor binding, histone modifications, and gene expression levels.

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Narcolepsy risk loci are enriched in immune cells and suggest autoimmune modulation of the T cell receptor repertoire

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msCentipede: Modeling heterogeneity across genomic sites improves accuracy in the inference of transcription factor binding

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Genetic Variation, Not Cell Type of Origin, Underlies Regulatory Differences in iPSCs

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Determining the genetic basis of anthracycline-cardiotoxicity by molecular response QTL mapping in induced cardiomyocytes

genomics more details view paper
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SciReader*: A Cloud-based Recommender System for Biomedical Literature

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Frequent Non-Allelic Gene Conversion On The Human Lineage And Its Effect On The Divergence Of Gene Duplicates

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Reprogramming LCLs to iPSCs Results in Recovery of Donor-Specific Gene Expression Signature

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Epigenetic Modifications are Associated with Inter-species Gene Expression Variation in Primates

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Measurement of selective constraint on human gene expression

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Whole genome sequencing identifies a novel factor required for secretory granule maturation in Tetrahymena thermophila

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An evolutionary switch in the specificity of an endosomal CORVET tether underlies formation of regulated secretory vesicles in the ciliate Tetrahymena thermophila

cell biology more details view paper
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