Author: Jesse D. Bloom
- ORCiD: http://orcid.org/0000-0003-1267-3408
- Most recently observed institution: Howard Hughes Medical Institute
Rankings
- All-time downloads: 114,800 (rank: 729 )
- Categories:
- bioinformatics: 1,552 (rank: 8,632 (tie) )
- biophysics: 435 (rank: 10,428 (tie) )
- evolutionary biology: 8,077 (rank: 256 )
- genomics: 1,716 (rank: 12,527 (tie) )
- immunology: 1,841 (rank: 3,699 )
- infectious diseases: 29,112 (rank: 1,373 (tie) )
- microbiology: 70,882 (rank: 166 )
- molecular biology: 1,185 (rank: 4,107 (tie) )
Downloads per author, site-wide
Preprints
Neutralizing antibodies correlate with protection from SARS-CoV-2 in humans during a fishery vessel outbreak with high attack rate
infectious diseases more details view paper- Downloaded 24,871 times
- Download rankings, all-time:
- Site-wide: 234
- In infectious diseases: 91
- Year to date:
- Site-wide: 1,005
- Since beginning of last month:
- Site-wide: 779
Comprehensive mapping of mutations to the SARS-CoV-2 receptor-binding domain that affect recognition by polyclonal human serum antibodies
microbiology more details view paper- Downloaded 22,942 times
- Download rankings, all-time:
- Site-wide: 257
- In microbiology: 28
- Year to date:
- Site-wide: 3
- Since beginning of last month:
- Site-wide: None
Deep mutational scanning of SARS-CoV-2 receptor binding domain reveals constraints on folding and ACE2 binding
microbiology more details view paper- Downloaded 10,103 times
- Download rankings, all-time:
- Site-wide: 688
- In microbiology: 73
- Year to date:
- Site-wide: 389
- Since beginning of last month:
- Site-wide: 819
A human coronavirus evolves antigenically to escape antibody immunity
microbiology more details view paper- Downloaded 9,497 times
- Download rankings, all-time:
- Site-wide: 744
- In microbiology: 76
- Year to date:
- Site-wide: 104
- Since beginning of last month:
- Site-wide: 19
Protocol and reagents for pseudotyping lentiviral particles with SARS-CoV-2 Spike protein for neutralization assays
microbiology more details view paper- Downloaded 7,193 times
- Download rankings, all-time:
- Site-wide: 1,073
- In microbiology: 99
- Year to date:
- Site-wide: 1,115
- Since beginning of last month:
- Site-wide: 2,127
Prospective mapping of viral mutations that escape antibodies used to treat COVID-19
microbiology more details view paper- Downloaded 4,089 times
- Download rankings, all-time:
- Site-wide: 2,306
- In microbiology: 163
- Year to date:
- Site-wide: 126
- Since beginning of last month:
- Site-wide: 64
Complete mapping of mutations to the SARS-CoV-2 spike receptor-binding domain that escape antibody recognition
microbiology more details view paper- Downloaded 3,282 times
- Download rankings, all-time:
- Site-wide: 3,197
- In microbiology: 208
- Year to date:
- Site-wide: 479
- Since beginning of last month:
- Site-wide: 1,490
Seroprevalence of SARS-CoV-2 among children visiting a hospital during the initial Seattle outbreak
infectious diseases more details view paper- Downloaded 2,733 times
- Download rankings, all-time:
- Site-wide: 4,114
- In infectious diseases: 652
- Year to date:
- Site-wide: 26,579
- Since beginning of last month:
- Site-wide: 17,502
Single-cell virus sequencing of influenza infections that trigger innate immunity
microbiology more details view paper- Downloaded 2,344 times
- Download rankings, all-time:
- Site-wide: 5,209
- In microbiology: 301
- Year to date:
- Site-wide: 67,901
- Since beginning of last month:
- Site-wide: 45,403
Dynamics of neutralizing antibody titers in the months after SARS-CoV-2 infection
infectious diseases more details view paper- Downloaded 1,508 times
- Download rankings, all-time:
- Site-wide: 10,001
- In infectious diseases: 1,092
- Year to date:
- Site-wide: 8,854
- Since beginning of last month:
- Site-wide: 4,236
An experimentally determined evolutionary model dramatically improves phylogenetic fit
evolutionary biology more details view paper- Downloaded 1,488 times
- Download rankings, all-time:
- Site-wide: 10,194
- In evolutionary biology: 351
- Year to date:
- Site-wide: 47,446
- Since beginning of last month:
- Site-wide: 76,589
Identification of positive selection in genes is greatly improved by using experimentally informed site-specific models
evolutionary biology more details view paper- Downloaded 1,374 times
- Download rankings, all-time:
- Site-wide: 11,503
- In evolutionary biology: 422
- Year to date:
- Site-wide: 75,989
- Since beginning of last month:
- Site-wide: 99,535
Extreme heterogeneity of influenza virus infection in single cells
genomics more details view paper- Downloaded 1,340 times
- Download rankings, all-time:
- Site-wide: 11,938
- In genomics: 1,337
- Year to date:
- Site-wide: 81,051
- Since beginning of last month:
- Site-wide: 94,463
Expanding the Atlas of Functional Missense Variation for Human Genes
molecular biology more details view paper- Downloaded 1,185 times
- Download rankings, all-time:
- Site-wide: 14,358
- In molecular biology: 401
- Year to date:
- Site-wide: 103,505
- Since beginning of last month:
- Site-wide: 70,940
The inherent mutational tolerance and antigenic evolvability of influenza hemagglutinin
microbiology more details view paper- Downloaded 1,087 times
- Download rankings, all-time:
- Site-wide: 16,375
- In microbiology: 918
- Year to date:
- Site-wide: 96,278
- Since beginning of last month:
- Site-wide: 87,743
Reconciling disparate estimates of viral genetic diversity during human influenza infections
evolutionary biology more details view paper- Downloaded 1,065 times
- Download rankings, all-time:
- Site-wide: 16,877
- In evolutionary biology: 717
- Year to date:
- Site-wide: 66,817
- Since beginning of last month:
- Site-wide: 91,155
An experimentally informed evolutionary model improves phylogenetic fit to divergent lactamase homologs
evolutionary biology more details view paper- Downloaded 1,043 times
- Download rankings, all-time:
- Site-wide: 17,378
- In evolutionary biology: 744
- Year to date:
- Site-wide: 91,652
- Since beginning of last month:
- Site-wide: 120,838
Comprehensive profiling of translation initiation in influenza virus infected cells
microbiology more details view paper- Downloaded 913 times
- Download rankings, all-time:
- Site-wide: 21,147
- In microbiology: 1,198
- Year to date:
- Site-wide: 30,416
- Since beginning of last month:
- Site-wide: 46,736
Software for the analysis and visualization of deep mutational scanning data
bioinformatics more details view paper- Downloaded 887 times
- Download rankings, all-time:
- Site-wide: 22,095
- In bioinformatics: 2,694
- Year to date:
- Site-wide: 69,356
- Since beginning of last month:
- Site-wide: 102,633
Attenuated influenza virions expressing the SARS-CoV-2 receptor-binding domain induce neutralizing antibodies in mice
microbiology more details view paper- Downloaded 798 times
- Download rankings, all-time:
- Site-wide: 25,640
- In microbiology: 1,495
- Year to date:
- Site-wide: 8,263
- Since beginning of last month:
- Site-wide: 20,658
Experimental estimation of the effects of all amino-acid mutations to HIV Env
microbiology more details view paper- Downloaded 783 times
- Download rankings, all-time:
- Site-wide: 26,297
- In microbiology: 1,535
- Year to date:
- Site-wide: 116,346
- Since beginning of last month:
- Site-wide: 67,287
An antigenic atlas of HIV-1 escape from broadly neutralizing antibodies
immunology more details view paper- Downloaded 736 times
- Download rankings, all-time:
- Site-wide: 28,692
- In immunology: 765
- Year to date:
- Site-wide: 78,400
- Since beginning of last month:
- Site-wide: 101,018
Linking influenza virus evolution within and between human hosts
evolutionary biology more details view paper- Downloaded 735 times
- Download rankings, all-time:
- Site-wide: 28,774
- In evolutionary biology: 1,451
- Year to date:
- Site-wide: 67,955
- Since beginning of last month:
- Site-wide: 73,064
Deep mutational scanning of hemagglutinin helps predict evolutionary fates of human H3N2 influenza variants
evolutionary biology more details view paper- Downloaded 733 times
- Download rankings, all-time:
- Site-wide: 28,861
- In evolutionary biology: 1,457
- Year to date:
- Site-wide: 54,877
- Since beginning of last month:
- Site-wide: 42,377
Mapping person-to-person variation in viral mutations that escape polyclonal serum targeting influenza hemagglutinin
microbiology more details view paper- Downloaded 717 times
- Download rankings, all-time:
- Site-wide: 29,740
- In microbiology: 1,768
- Year to date:
- Site-wide: 26,034
- Since beginning of last month:
- Site-wide: 104,704
Site-specific amino-acid preferences are mostly conserved in two closely related protein homologs
evolutionary biology more details view paper- Downloaded 715 times
- Download rankings, all-time:
- Site-wide: 29,871
- In evolutionary biology: 1,526
- Year to date:
- Site-wide: 87,848
- Since beginning of last month:
- Site-wide: 95,752
Complete mapping of viral escape from neutralizing antibodies
microbiology more details view paper- Downloaded 700 times
- Download rankings, all-time:
- Site-wide: 30,714
- In microbiology: 1,820
- Year to date:
- Site-wide: 93,193
- Since beginning of last month:
- Site-wide: 88,488
Phage-DMS: a comprehensive method for fine mapping of antibody epitopes
immunology more details view paper- Downloaded 644 times
- Download rankings, all-time:
- Site-wide: 34,372
- In immunology: 909
- Year to date:
- Site-wide: 36,207
- Since beginning of last month:
- Site-wide: 64,844
Quantifying the effects of single mutations on viral escape from broad and narrow antibodies to an H1 influenza hemagglutinin
microbiology more details view paper- Downloaded 637 times
- Download rankings, all-time:
- Site-wide: 34,883
- In microbiology: 2,075
- Year to date:
- Site-wide: 110,346
- Since beginning of last month:
- Site-wide: 76,585
Comprehensive mapping of avian influenza polymerase adaptation to the human host
microbiology more details view paper- Downloaded 635 times
- Download rankings, all-time:
- Site-wide: 34,960
- In microbiology: 2,085
- Year to date:
- Site-wide: 66,101
- Since beginning of last month:
- Site-wide: 113,686
Comprehensive mapping of HIV-1 escape from a broadly neutralizing antibody
microbiology more details view paper- Downloaded 628 times
- Download rankings, all-time:
- Site-wide: 35,531
- In microbiology: 2,132
- Year to date:
- Site-wide: 76,401
- Since beginning of last month:
- Site-wide: 78,250
Deep mutational scanning identifies sites in influenza nucleoprotein that affect viral inhibition by MxA
microbiology more details view paper- Downloaded 595 times
- Download rankings, all-time:
- Site-wide: 37,990
- In microbiology: 2,317
- Year to date:
- Site-wide: 110,972
- Since beginning of last month:
- Site-wide: 92,047
Deep mutational scanning comprehensively maps how Zika envelope protein mutations affect viral growth and antibody escape
microbiology more details view paper- Downloaded 533 times
- Download rankings, all-time:
- Site-wide: 43,640
- In microbiology: 2,710
- Year to date:
- Site-wide: 90,520
- Since beginning of last month:
- Site-wide: 51,148
Accurate measurement of the effects of all amino-acid mutations to influenza hemagglutinin
microbiology more details view paper- Downloaded 532 times
- Download rankings, all-time:
- Site-wide: 43,715
- In microbiology: 2,721
- Year to date:
- Site-wide: 108,861
- Since beginning of last month:
- Site-wide: 74,742
Mapping mutational effects along the evolutionary landscape of HIV envelope
microbiology more details view paper- Downloaded 523 times
- Download rankings, all-time:
- Site-wide: 44,627
- In microbiology: 2,799
- Year to date:
- Site-wide: 102,958
- Since beginning of last month:
- Site-wide: 101,532
Modeling site-specific amino-acid preferences deepens phylogenetic estimates of viral divergence
evolutionary biology more details view paper- Downloaded 494 times
- Download rankings, all-time:
- Site-wide: 47,690
- In evolutionary biology: 2,689
- Year to date:
- Site-wide: 87,398
- Since beginning of last month:
- Site-wide: 114,483
Complete functional mapping of infection- and vaccine-elicited antibodies against the fusion peptide of HIV
immunology more details view paper- Downloaded 461 times
- Download rankings, all-time:
- Site-wide: 51,558
- In immunology: 1,365
- Year to date:
- Site-wide: 106,499
- Since beginning of last month:
- Site-wide: 116,318
When two are better than one: Modeling the mechanisms of antibody mixtures
biophysics more details view paper- Downloaded 435 times
- Download rankings, all-time:
- Site-wide: 54,962
- In biophysics: 1,947
- Year to date:
- Site-wide: 59,295
- Since beginning of last month:
- Site-wide: 89,489
phydms: Software for phylogenetic analyses informed by deep mutational scanning
evolutionary biology more details view paper- Downloaded 430 times
- Download rankings, all-time:
- Site-wide: 55,627
- In evolutionary biology: 3,153
- Year to date:
- Site-wide: 106,644
- Since beginning of last month:
- Site-wide: 121,849
Identification of antibodies targeting the H3N2 hemagglutinin receptor binding site following vaccination of humans
microbiology more details view paper- Downloaded 426 times
- Download rankings, all-time:
- Site-wide: 56,065
- In microbiology: 3,712
- Year to date:
- Site-wide: 103,054
- Since beginning of last month:
- Site-wide: 118,030
Influenza H3 and H1 hemagglutinins have different genetic barriers for resistance to broadly neutralizing stem antibodies
microbiology more details view paper- Downloaded 411 times
- Download rankings, all-time:
- Site-wide: 58,251
- In microbiology: 3,882
- Year to date:
- Site-wide: 60,945
- Since beginning of last month:
- Site-wide: 47,378
Estimating the frequency of multiplets in single-cell RNA sequencing from cell-mixing experiments
genomics more details view paper- Downloaded 376 times
- Download rankings, all-time:
- Site-wide: 63,507
- In genomics: 4,576
- Year to date:
- Site-wide: None
- Since beginning of last month:
- Site-wide: 103,665
Cooperating H3N2 influenza virus variants are not detectable in primary clinical samples
microbiology more details view paper- Downloaded 361 times
- Download rankings, all-time:
- Site-wide: 65,969
- In microbiology: 4,489
- Year to date:
- Site-wide: 75,900
- Since beginning of last month:
- Site-wide: 90,826
alignparse: A Python package for parsing complex features from high-throughput long-read sequencing
bioinformatics more details view paper- Downloaded 361 times
- Download rankings, all-time:
- Site-wide: 65,860
- In bioinformatics: 6,445
- Year to date:
- Site-wide: 90,071
- Since beginning of last month:
- Site-wide: 120,487
dms-view: Interactive visualization tool for deep mutational scanning data
bioinformatics more details view paper- Downloaded 304 times
- Download rankings, all-time:
- Site-wide: 75,884
- In bioinformatics: 7,080
- Year to date:
- Site-wide: 79,425
- Since beginning of last month:
- Site-wide: 33,986
Sera from individuals with narrowly focused influenza virus antibodies rapidly select viral escape mutations in ovo
microbiology more details view paper- Downloaded 290 times
- Download rankings, all-time:
- Site-wide: 78,613
- In microbiology: 5,555
- Year to date:
- Site-wide: 87,451
- Since beginning of last month:
- Site-wide: 96,562
Massively parallel profiling of HIV-1 resistance to the fusion inhibitor enfuvirtide
microbiology more details view paper- Downloaded 222 times
- Download rankings, all-time:
- Site-wide: 92,653
- In microbiology: 6,791
- Year to date:
- Site-wide: 60,126
- Since beginning of last month:
- Site-wide: 91,045
High-resolution mapping of the neutralizing and binding specificities of polyclonal rabbit serum elicited by HIV Env trimer immunization
microbiology more details view paper- Downloaded 190 times
- Download rankings, all-time:
- Site-wide: 99,537
- In microbiology: 7,461
- Year to date:
- Site-wide: 46,376
- Since beginning of last month:
- Site-wide: 36,461
Identification of HIV-1 Envelope Mutations that Enhance Entry Using Macaque CD4 and CCR5
microbiology more details view paper- Downloaded 164 times
- Download rankings, all-time:
- Site-wide: 104,634
- In microbiology: 7,904
- Year to date:
- Site-wide: 71,115
- Since beginning of last month:
- Site-wide: 106,423
Antibody neutralization of an influenza virus that uses neuraminidase for receptor binding
microbiology more details view paper- Downloaded 149 times
- Download rankings, all-time:
- Site-wide: 107,515
- In microbiology: 8,174
- Year to date:
- Site-wide: 118,431
- Since beginning of last month:
- Site-wide: 74,827
APOBEC3C tandem domain proteins create super restriction factors against HIV-1
microbiology more details view paper- Downloaded 138 times
- Download rankings, all-time:
- Site-wide: 109,452
- In microbiology: 8,342
- Year to date:
- Site-wide: 99,866
- Since beginning of last month:
- Site-wide: 110,897
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