Author: P Eline Slagboom

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Preprints

A reference panel of 64,976 haplotypes for genotype imputation

• Downloaded 4,562 times
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  • Site-wide: 1,960
  • In genetics: 79
• Year to date:
  • Site-wide: 81,239
• Since beginning of last month:
  • Site-wide: 53,989

Ninety-nine independent genetic loci influencing general cognitive function include genes associated with brain health and structure (N = 280,360)

• Downloaded 3,210 times
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  • Site-wide: 3,288
  • In genetics: 146
• Year to date:
  • Site-wide: 20,223
• Since beginning of last month:
  • Site-wide: 40,423

Blood biomarker score identifies individuals at high risk for severe COVID-19 a decade prior to diagnosis: metabolic profiling of 105,000 adults in the UK Biobank

• Downloaded 2,288 times
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  • Site-wide: 5,361
  • In epidemiology: 431
• Year to date:
  • Site-wide: 3,686
• Since beginning of last month:
  • Site-wide: 6,765

A high-quality reference panel reveals the complexity and distribution of structural genome changes in a human population

• Downloaded 1,260 times
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  • Site-wide: 13,025
  • In genetics: 677
• Year to date:
  • Site-wide: 59,435
• Since beginning of last month:
  • Site-wide: 87,769

Controlling bias and inflation in epigenome- and transcriptome-wide association studies using the empirical null distribution

• Downloaded 1,114 times
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  • Site-wide: 15,653
  • In genomics: 1,688
• Year to date:
  • Site-wide: 53,268
• Since beginning of last month:
  • Site-wide: 47,552

Genome-wide identification of directed gene networks using large-scale population genomics data

• Downloaded 708 times
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  • Site-wide: 30,020
  • In genomics: 2,752
• Year to date:
  • Site-wide: 52,233
• Since beginning of last month:
  • Site-wide: 101,913

The genomic architecture of blood metabolites based on a decade of genome-wide analyses

• Downloaded 666 times
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  • Site-wide: 32,625
  • In genetics: 1,639
• Year to date:
  • Site-wide: 66,892
• Since beginning of last month:
  • Site-wide: 54,188

DYNAMIC CLONAL HEMATOPOIESIS AND FUNCTIONAL T-CELL IMMUNITY IN A SUPER-CENTENARIAN

• Downloaded 632 times
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  • Site-wide: 34,934
  • In immunology: 921
• Year to date:
  • Site-wide: 48,418
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  • Site-wide: 18,743

Predicting biological age based on the BBMRI-NL 1H-NMR metabolomics repository

• Downloaded 606 times
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  • Site-wide: 36,895
  • In epidemiology: 1,724
• Year to date:
  • Site-wide: 90,417
• Since beginning of last month:
  • Site-wide: 59,834

Shared Genetic Risk between Eating Disorder- and Substance-Use-Related Phenotypes: Evidence from Genome-Wide Association Studies

• Downloaded 560 times
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  • Site-wide: 40,742
  • In genetics: 2,002
• Year to date:
  • Site-wide: 29,305
• Since beginning of last month:
  • Site-wide: 75,007

Genomic and phenomic insights from an atlas of genetic effects on DNA methylation

• Downloaded 507 times
• Download rankings, all-time:
  • Site-wide: 45,873
  • In genetic and genomic medicine: 113
• Year to date:
  • Site-wide: 5,446
• Since beginning of last month:
  • Site-wide: 8,706

Genome-wide identification of genes regulating DNA methylation using genetic anchors for causal inference

• Downloaded 506 times
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  • Site-wide: 46,015
  • In genomics: 3,740
• Year to date:
  • Site-wide: 44,062
• Since beginning of last month:
  • Site-wide: 85,577

Longevity Relatives Count score identifies heritable longevity carriers and suggests case improvement in genetic studies

• Downloaded 426 times
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  • Site-wide: 55,733
  • In genetics: 2,694
• Year to date:
  • Site-wide: 50,051
• Since beginning of last month:
  • Site-wide: 71,289

Longevity defined as top 10% survivors is transmitted as a quantitative genetic trait: results from large three-generation datasets

• Downloaded 339 times
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  • Site-wide: 69,171
  • In genetics: 3,283
• Year to date:
  • Site-wide: 89,321
• Since beginning of last month:
  • Site-wide: 100,764

Correction for both common and rare cell types in blood is important to identify genes that correlate with age

• Downloaded 262 times
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  • Site-wide: 83,876
  • In bioinformatics: 7,614
• Year to date:
  • Site-wide: 72,786
• Since beginning of last month:
  • Site-wide: 55,552

Intergenerational transmission of longevity is not affected by other familial factors: Evidence from 16,905 Dutch families from Zeeland, 1812-1962

• Downloaded 211 times
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  • Site-wide: 94,541
  • In genetics: 4,369
• Year to date:
  • Site-wide: 51,534
• Since beginning of last month:
  • Site-wide: 116,824

Lifestyle-intervention-induced reduction of abdominal fat is reflected by a decreased circulating glycerol level and an increased HDL diameter

• Downloaded 155 times
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  • Site-wide: 105,914
  • In molecular biology: 3,191
• Year to date:
  • Site-wide: 85,847
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  • Site-wide: 65,552

Investigating the relationships between unfavorable sleep and metabolomic traits: evidence from multi-cohort multivariable regression and Mendelian randomization analyses

• Downloaded 104 times
• Download rankings, all-time:
  • Site-wide: 114,835
  • In epidemiology: 4,578
• Year to date:
  • Site-wide: None
• Since beginning of last month:
  • Site-wide: 103,540