Rxivist combines preprints from bioRxiv with data from Twitter to help you find the papers being discussed in your field. Currently indexing 70,653 bioRxiv papers from 308,421 authors.

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Preprints

Genomewide association study identifies 30 loci associated with bipolar disorder

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  • In genetics: 32 out of 3,913
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Unraveling the polygenic architecture of complex traits using blood eQTL meta-analysis

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  • In genomics: 80 out of 4,714
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  • Site-wide: 800 out of 70,616
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  • Site-wide: 914 out of 70,616

Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences

• Downloaded 3,137 times
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  • In genetics: 100 out of 3,913
• Year to date:
  • Site-wide: 12,377 out of 70,616
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  • Site-wide: 15,894 out of 70,616

Improved polygenic prediction by Bayesian multiple regression on summary statistics

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  • In genetics: 173 out of 3,913
• Year to date:
  • Site-wide: 5,823 out of 70,616
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  • Site-wide: 3,214 out of 70,616

Cell specific eQTL analysis without sorting cells

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  • In genetics: 257 out of 3,913
• Year to date:
  • Site-wide: 16,790 out of 70,616
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  • Site-wide: 7,845 out of 70,616

Genome-wide association study identifies 48 common genetic variants associated with handedness

• Downloaded 1,763 times
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  • In genetics: 274 out of 3,913
• Year to date:
  • Site-wide: 2,553 out of 70,616
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  • Site-wide: 2,225 out of 70,616

A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects

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  • In genetics: 309 out of 3,913
• Year to date:
  • Site-wide: 31,993 out of 70,616
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  • Site-wide: 39,297 out of 70,616

Genetic Associations with Subjective Well-Being Also Implicate Depression and Neuroticism

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  • In genetics: 339 out of 3,913
• Year to date:
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Human loss-of-function variants suggest that partial LRRK2 inhibition is a safe therapeutic strategy for Parkinson’s disease

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  • In genomics: 780 out of 4,714
• Year to date:
  • Site-wide: 7,317 out of 70,616
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  • Site-wide: 4,694 out of 70,616

Educational attainment and personality are genetically intertwined

• Downloaded 1,420 times
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  • In genetics: 386 out of 3,913
• Year to date:
  • Site-wide: 18,218 out of 70,616
• Since beginning of last month:
  • Site-wide: 14,383 out of 70,616

PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

• Downloaded 1,248 times
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  • In genetics: 454 out of 3,913
• Year to date:
  • Site-wide: 13,025 out of 70,616
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  • Site-wide: 15,481 out of 70,616

Genome-wide association study provides new insights into the genetic architecture and pathogenesis of heart failure

• Downloaded 1,190 times
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  • In genetics: 486 out of 3,913
• Year to date:
  • Site-wide: 2,192 out of 70,616
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  • Site-wide: 1,877 out of 70,616

Mega-analysis of 31,396 individuals from 6 countries uncovers strong gene-environment interaction for human fertility

• Downloaded 903 times
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  • In genomics: 1,447 out of 4,714
• Year to date:
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  • Site-wide: 32,663 out of 70,616

An epigenome-wide association study of educational attainment (n = 10,767)

• Downloaded 865 times
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  • In genetics: 758 out of 3,913
• Year to date:
  • Site-wide: 57,112 out of 70,616
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  • Site-wide: 54,575 out of 70,616

Comprehensive population-based genome sequencing provides insight into hematopoietic regulatory mechanisms

• Downloaded 675 times
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  • Site-wide: 15,058 out of 70,616
  • In genetics: 1,031 out of 3,913
• Year to date:
  • Site-wide: 63,056 out of 70,616
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  • Site-wide: 34,812 out of 70,616

Identifying tissues implicated in Anorexia Nervosa using Transcriptomic Imputation

• Downloaded 627 times
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  • Site-wide: 16,750 out of 70,616
  • In genetics: 1,135 out of 3,913
• Year to date:
  • Site-wide: 51,316 out of 70,616
• Since beginning of last month:
  • Site-wide: 11,112 out of 70,616

Allele-specific expression changes dynamically during T cell activation in HLA and other autoimmune loci

• Downloaded 620 times
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  • Site-wide: 17,011 out of 70,616
  • In genomics: 2,106 out of 4,714
• Year to date:
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• Since beginning of last month:
  • Site-wide: 8,788 out of 70,616

Functional and evolutionary impact of polymorphic inversions in the human genome

• Downloaded 591 times
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  • Site-wide: 18,216 out of 70,616
  • In genomics: 2,201 out of 4,714
• Year to date:
  • Site-wide: 47,126 out of 70,616
• Since beginning of last month:
  • Site-wide: 21,859 out of 70,616

Constraints on eQTL fine mapping in the presence of multi-site local regulation of gene expression

• Downloaded 577 times
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  • Site-wide: 18,834 out of 70,616
  • In genetics: 1,250 out of 3,913
• Year to date:
  • Site-wide: 58,476 out of 70,616
• Since beginning of last month:
  • Site-wide: 65,652 out of 70,616

Genome-wide Association Study of Clinical Features in the Schizophrenia Psychiatric Genomics Consortium: Confirmation of Polygenic Effect on Negative Symptoms

• Downloaded 564 times
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  • Site-wide: 19,416 out of 70,616
  • In genetics: 1,284 out of 3,913
• Year to date:
  • Site-wide: 59,603 out of 70,616
• Since beginning of last month:
  • Site-wide: 41,978 out of 70,616

PAIRUP-MS: Pathway Analysis and Imputation to Relate Unknowns in Profiles from Mass Spectrometry-based metabolite data

• Downloaded 320 times
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  • Site-wide: 36,809 out of 70,616
  • In bioinformatics: 4,526 out of 6,912
• Year to date:
  • Site-wide: 52,857 out of 70,616
• Since beginning of last month:
  • Site-wide: 66,761 out of 70,616

Analytical strategies to include the X-chromosome in variance heterogeneity analyses: evidence for trait-specific polygenic variance structure

• Downloaded 307 times
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  • Site-wide: 38,097 out of 70,616
  • In genetics: 2,343 out of 3,913
• Year to date:
  • Site-wide: 27,877 out of 70,616
• Since beginning of last month:
  • Site-wide: 31,525 out of 70,616

Shared Genetic Risk between Eating Disorder- and Substance-Use-Related Phenotypes: Evidence from Genome-Wide Association Studies

• Downloaded 297 times
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  • Site-wide: 39,224 out of 70,616
  • In genetics: 2,386 out of 3,913
• Year to date:
  • Site-wide: 14,643 out of 70,616
• Since beginning of last month:
  • Site-wide: 26,854 out of 70,616

Integrating untargeted metabolomics, genetically informed causal inference, and pathway enrichment to define the obesity metabolome

• Downloaded 182 times
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  • Site-wide: 54,437 out of 70,616
  • In bioinformatics: 5,876 out of 6,912
• Year to date:
  • Site-wide: 21,608 out of 70,616
• Since beginning of last month:
  • Site-wide: 41,128 out of 70,616

Polymorphic inversions underlie the shared genetic susceptibility to prevalent common diseases

• Downloaded 153 times
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  • Site-wide: 58,740 out of 70,616
  • In genetics: 3,403 out of 3,913
• Year to date:
  • Site-wide: 32,078 out of 70,616
• Since beginning of last month:
  • Site-wide: 2,574 out of 70,616