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Author: Tonu Esko

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    • bioinformatics: 547 (rank: 15,521 (tie) out of 28,805)
    • genetics: 29,704 (rank: 152 out of 32,435)
    • genomics: 12,006 (rank: 942 out of 36,880)

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Preprints

Unraveling the polygenic architecture of complex traits using blood eQTL meta-analysis

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Genomewide association study identifies 30 loci associated with bipolar disorder

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Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences

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Improved polygenic prediction by Bayesian multiple regression on summary statistics

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Cell specific eQTL analysis without sorting cells

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Genome-wide association study identifies 48 common genetic variants associated with handedness

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A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects

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Human loss-of-function variants suggest that partial LRRK2 inhibition is a safe therapeutic strategy for Parkinson’s disease

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Genetic Associations with Subjective Well-Being Also Implicate Depression and Neuroticism

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Educational attainment and personality are genetically intertwined

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PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

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Genome-wide association study provides new insights into the genetic architecture and pathogenesis of heart failure

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Trans-ethnic and ancestry-specific blood-cell genetics in 746,667 individuals from 5 global populations

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Genomic analyses for age at menarche identify 389 independent signals and indicate BMI-independent effects of puberty timing on cancer susceptibility

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Mega-analysis of 31,396 individuals from 6 countries uncovers strong gene-environment interaction for human fertility

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An epigenome-wide association study of educational attainment (n = 10,767)

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Allele-specific expression changes dynamically during T cell activation in HLA and other autoimmune loci

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Comprehensive population-based genome sequencing provides insight into hematopoietic regulatory mechanisms

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Identifying tissues implicated in Anorexia Nervosa using Transcriptomic Imputation

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Using genetics to disentangle the complex relationship between food choices and health status

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Functional and evolutionary impact of polymorphic inversions in the human genome

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Constraints on eQTL fine mapping in the presence of multi-site local regulation of gene expression

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Genome-wide Association Study of Clinical Features in the Schizophrenia Psychiatric Genomics Consortium: Confirmation of Polygenic Effect on Negative Symptoms

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The effect of X-linked dosage compensation on complex trait variation

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PAIRUP-MS: Pathway Analysis and Imputation to Relate Unknowns in Profiles from Mass Spectrometry-based metabolite data

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Analytical strategies to include the X-chromosome in variance heterogeneity analyses: evidence for trait-specific polygenic variance structure

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Genome-wide study identifies association between HLA-B*55:01 and penicillin allergy

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Integrating untargeted metabolomics, genetically informed causal inference, and pathway enrichment to define the obesity metabolome

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MADloy: Robust detection of mosaic loss of chromosome Y from genotype-array-intensity data

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