Author: Konstantin Strauch

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Preprints

Genome-wide association studies identify 137 loci for DNA methylation biomarkers of ageing

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DeepWAS: Multivariate genotype-phenotype associations by directly integrating regulatory information using deep learning

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Fine-mapping of an expanded set of type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps

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Cell specific eQTL analysis without sorting cells

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Refining The Accuracy Of Validated Target Identification Through Coding Variant Fine-Mapping In Type 2 Diabetes

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Connecting genetic risk to disease endpoints through the human blood plasma proteome

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Genetic discovery and translational decision support from exome sequencing of 20,791 type 2 diabetes cases and 24,440 controls from five ancestries

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PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

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Genomic analyses for age at menarche identify 389 independent signals and indicate BMI-independent effects of puberty timing on cancer susceptibility

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Characterization of missing values in untargeted MS-based metabolomics data and evaluation of missing data handling strategies

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Genome-wide methylation data mirror ancestry information

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Tissue-Specific Alteration of Metabolic Pathways Influences Glycemic Regulation

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Multi-ancestry GWAS of the electrocardiographic PR interval identifies 210 loci underlying cardiac conduction

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Discovering patterns of pleiotropy in genome-wide association studies

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Genome-wide association meta-analysis of PR interval identifies 47 novel loci associated with atrial and atrioventricular electrical activity

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Multi-ancestry analysis of gene-sleep interactions in 126,926 individuals identifies multiple novel blood lipid loci that contribute to our understanding of sleep-associated adverse blood lipid profile

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Meta-analysis of exome array data identifies six novel genetic loci for lung function

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Cis-epistasis at the LPA locus and risk of coronary artery disease

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Network reconstruction for trans acting genetic loci using multi-omics data and prior information

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Genome wide association analysis in dilated cardiomyopathy reveals two new key players in systolic heart failure on chromosome 3p25.1 and 22q11.23

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Evaluation of the causal effect of fibrinogen on incident coronary heart disease via Mendelian randomization

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A genome-wide analysis of DNA methylation identifies a novel association signal for Lp(a) concentrations in the LPA promoter

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Biomarker-based outcome prediction in prostate adenocarcinoma depends on the TMPRSS2-ERG status

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Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure

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