Author: Igor Rudan

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Preprints

Ancient human genomes suggest three ancestral populations for present-day Europeans

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Ninety-nine independent genetic loci influencing general cognitive function include genes associated with brain health and structure (N = 280,360)

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  • Site-wide: 3,677
  • In genetics: 151
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  • Site-wide: 40,507
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  • Site-wide: 87,050

Genetic analysis of over one million people identifies 535 novel loci for blood pressure.

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  • Site-wide: 3,975
  • In genetics: 168
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  • Site-wide: 54,308
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Genome-wide association study identifies 48 common genetic variants associated with handedness

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  • Site-wide: 5,158
  • In genetics: 235
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Genetic Associations with Subjective Well-Being Also Implicate Depression and Neuroticism

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  • Site-wide: 9,441
  • In genetics: 453
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  • Site-wide: 75,488
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PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

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  • Site-wide: 9,872
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  • Site-wide: 64,880
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  • Site-wide: 45,358

New genetic signals for lung function highlight pathways and pleiotropy, and chronic obstructive pulmonary disease associations across multiple ancestries

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  • Site-wide: 10,607
  • In genomics: 1,152
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  • Site-wide: 74,515
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  • Site-wide: 89,263

Genomic analyses for age at menarche identify 389 independent signals and indicate BMI-independent effects of puberty timing on cancer susceptibility

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  • Site-wide: 15,227
  • In genomics: 1,578
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  • Site-wide: 87,318
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  • Site-wide: 120,296

Genome-wide association and functional studies identify 46 novel loci for alcohol consumption and suggest common genetic mechanisms with neuropsychiatric disorders

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Proteome-by-phenome Mendelian Randomisation detects 38 proteins with causal roles in human diseases and traits

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  • In genomics: 1,695
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Tissue-Specific Alteration of Metabolic Pathways Influences Glycemic Regulation

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  • In genetics: 1,223
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  • Site-wide: 10,875

The Trans-Ancestral Genomic Architecture of Glycaemic Traits

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  • Site-wide: 29,119
  • In genetics: 1,409
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  • Site-wide: 14,029
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  • Site-wide: 10,559

Novel blood pressure locus and gene discovery using GWAS and expression datasets from blood and the kidney

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  • Site-wide: 31,472
  • In genomics: 2,814
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  • Site-wide: 108,316

Multi-ancestry GWAS of the electrocardiographic PR interval identifies 210 loci underlying cardiac conduction

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  • Site-wide: 41,204
  • In genetics: 1,953
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Genetic insights into the biological mechanisms governing human ovarian ageing

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  • Site-wide: 43,555
  • In sexual and reproductive health: 18
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  • Site-wide: 2,346
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  • Site-wide: 7,099

Discovering patterns of pleiotropy in genome-wide association studies

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  • Site-wide: 115,324
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  • Site-wide: 97,468

Genome-wide association meta-analysis of PR interval identifies 47 novel loci associated with atrial and atrioventricular electrical activity

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  • Site-wide: 45,109
  • In genetics: 2,121
• Year to date:
  • Site-wide: 93,053
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  • Site-wide: 79,064

Global variability of the human IgG glycome

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  • Site-wide: 47,600
  • In biochemistry: 1,226
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  • Site-wide: 90,550
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A strategy to incorporate prior knowledge into correlation network cutoff selection

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  • Site-wide: 64,406
  • In bioinformatics: 6,276
• Year to date:
  • Site-wide: 91,739
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  • Site-wide: 99,527

Systematic evaluation of normalization methods for glycomics data based on performance of network inference

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  • Site-wide: 98,847
  • In bioinformatics: 8,508
• Year to date:
  • Site-wide: 104,014
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  • Site-wide: 84,294

A multi-omics study of circulating phospholipid markers of blood pressure

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  • Site-wide: 127,138
  • In cardiovascular medicine: 344
• Year to date:
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  • Site-wide: 93,882