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Author: Andres Metspalu

  • ORCiD: http://orcid.org/0000-0002-3718-796X
  • Most recently observed institution: Estonian Genome Center, Institute of Genomics, University of Tartu, Riia 23b, 51010, Tartu, Estonia

Rankings

  • All-time downloads: 70,630 (rank: 2,226 )
  • Categories:
    • bioinformatics: 775 (rank: 19,956 (tie) )
    • epidemiology: 356 (rank: 21,412 (tie) )
    • genetic and genomic medicine: 3,415 (rank: 924 )
    • genetics: 52,358 (rank: 75 )
    • genomics: 11,021 (rank: 1,872 )
    • hiv aids: 1,567 (rank: 70 (tie) )
    • sexual and reproductive health: 1,138 (rank: 163 (tie) )

Downloads per author, site-wide

Preprints

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

genetics more details view paper
  • Downloaded 9,444 times
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    • Site-wide: 1,011
    • In genetics: 26
  • Year to date:
    • Site-wide: 46,750
  • Since beginning of last month:
    • Site-wide: 73,195

Genomewide association study identifies 30 loci associated with bipolar disorder

genetics more details view paper
  • Downloaded 7,426 times
  • Download rankings, all-time:
    • Site-wide: 1,379
    • In genetics: 41
  • Year to date:
    • Site-wide: 24,321
  • Since beginning of last month:
    • Site-wide: 31,465

Fine-mapping of an expanded set of type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps

genomics more details view paper
  • Downloaded 3,277 times
  • Download rankings, all-time:
    • Site-wide: 4,265
    • In genomics: 440
  • Year to date:
    • Site-wide: 83,079
  • Since beginning of last month:
    • Site-wide: 58,254

Genetic analysis of over one million people identifies 535 novel loci for blood pressure.

genetics more details view paper
  • Downloaded 3,216 times
  • Download rankings, all-time:
    • Site-wide: 4,394
    • In genetics: 169
  • Year to date:
    • Site-wide: 34,228
  • Since beginning of last month:
    • Site-wide: 61,663

Improved polygenic prediction by Bayesian multiple regression on summary statistics

genetics more details view paper
  • Downloaded 2,833 times
  • Download rankings, all-time:
    • Site-wide: 5,248
    • In genetics: 218
  • Year to date:
    • Site-wide: 64,822
  • Since beginning of last month:
    • Site-wide: 83,213

Genome-wide association study identifies 48 common genetic variants associated with handedness

genetics more details view paper
  • Downloaded 2,672 times
  • Download rankings, all-time:
    • Site-wide: 5,708
    • In genetics: 244
  • Year to date:
    • Site-wide: 27,027
  • Since beginning of last month:
    • Site-wide: 34,570

Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine

genetics more details view paper
  • Downloaded 2,530 times
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    • Site-wide: 6,198
    • In genetics: 267
  • Year to date:
    • Site-wide: 112,624
  • Since beginning of last month:
    • Site-wide: 73,393

Ultra-rare disruptive and damaging mutations influence educational attainment in the general population

genetics more details view paper
  • Downloaded 2,331 times
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    • Site-wide: 6,988
    • In genetics: 309
  • Year to date:
    • Site-wide: 109,267
  • Since beginning of last month:
    • Site-wide: 34,946

Widespread signatures of negative selection in the genetic architecture of human complex traits

genetics more details view paper
  • Downloaded 2,328 times
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    • Site-wide: 6,998
    • In genetics: 311
  • Year to date:
    • Site-wide: 46,147
  • Since beginning of last month:
    • Site-wide: 33,094

Cell specific eQTL analysis without sorting cells

genetics more details view paper
  • Downloaded 2,015 times
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    • Site-wide: 8,627
    • In genetics: 374
  • Year to date:
    • Site-wide: 134,920
  • Since beginning of last month:
    • Site-wide: None

Refining The Accuracy Of Validated Target Identification Through Coding Variant Fine-Mapping In Type 2 Diabetes

genetics more details view paper
  • Downloaded 1,881 times
  • Download rankings, all-time:
    • Site-wide: 9,587
    • In genetics: 417
  • Year to date:
    • Site-wide: 100,017
  • Since beginning of last month:
    • Site-wide: 61,447

A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects

genetics more details view paper
  • Downloaded 1,830 times
  • Download rankings, all-time:
    • Site-wide: 9,959
    • In genetics: 444
  • Year to date:
    • Site-wide: 67,320
  • Since beginning of last month:
    • Site-wide: 31,534

Genetic Associations with Subjective Well-Being Also Implicate Depression and Neuroticism

genetics more details view paper
  • Downloaded 1,743 times
  • Download rankings, all-time:
    • Site-wide: 10,713
    • In genetics: 475
  • Year to date:
    • Site-wide: 93,551
  • Since beginning of last month:
    • Site-wide: 73,384

Genome-wide association analyses in >119,000 individuals identifies thirteen morningness and two sleep duration loci

genetics more details view paper
  • Downloaded 1,659 times
  • Download rankings, all-time:
    • Site-wide: 11,527
    • In genetics: 519
  • Year to date:
    • Site-wide: 114,661
  • Since beginning of last month:
    • Site-wide: None

A high-resolution HLA reference panel capturing global population diversity enables multi-ethnic fine-mapping in HIV host response

hiv aids more details view paper
  • Downloaded 1,567 times
  • Download rankings, all-time:
    • Site-wide: 12,491
    • In hiv aids: 7
  • Year to date:
    • Site-wide: 5,234
  • Since beginning of last month:
    • Site-wide: 8,360

Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes

genomics more details view paper
  • Downloaded 1,477 times
  • Download rankings, all-time:
    • Site-wide: 13,643
    • In genomics: 1,395
  • Year to date:
    • Site-wide: 105,006
  • Since beginning of last month:
    • Site-wide: 72,556

Trans-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation

genetic and genomic medicine more details view paper
  • Downloaded 1,440 times
  • Download rankings, all-time:
    • Site-wide: 14,198
    • In genetic and genomic medicine: 60
  • Year to date:
    • Site-wide: 6,285
  • Since beginning of last month:
    • Site-wide: 13,265

Genomic analyses for age at menarche identify 389 independent signals and indicate BMI-independent effects of puberty timing on cancer susceptibility

genomics more details view paper
  • Downloaded 1,262 times
  • Download rankings, all-time:
    • Site-wide: 17,317
    • In genomics: 1,697
  • Year to date:
    • Site-wide: 114,806
  • Since beginning of last month:
    • Site-wide: 34,081

The genetic architecture of sporadic and recurrent miscarriage

genetics more details view paper
  • Downloaded 1,187 times
  • Download rankings, all-time:
    • Site-wide: 18,951
    • In genetics: 883
  • Year to date:
    • Site-wide: 62,883
  • Since beginning of last month:
    • Site-wide: 84,346

Haplotype sharing provides insights into fine-scale population history and disease in Finland

genetics more details view paper
  • Downloaded 1,152 times
  • Download rankings, all-time:
    • Site-wide: 19,834
    • In genetics: 918
  • Year to date:
    • Site-wide: 84,476
  • Since beginning of last month:
    • Site-wide: 73,162

Genetic insights into the biological mechanisms governing human ovarian ageing

sexual and reproductive health more details view paper
  • Downloaded 1,138 times
  • Download rankings, all-time:
    • Site-wide: 20,197
    • In sexual and reproductive health: 15
  • Year to date:
    • Site-wide: 2,596
  • Since beginning of last month:
    • Site-wide: 1,980

The Trans-Ancestral Genomic Architecture of Glycaemic Traits

genetics more details view paper
  • Downloaded 1,074 times
  • Download rankings, all-time:
    • Site-wide: 22,003
    • In genetics: 1,004
  • Year to date:
    • Site-wide: 10,170
  • Since beginning of last month:
    • Site-wide: 44,082

Mega-analysis of 31,396 individuals from 6 countries uncovers strong gene-environment interaction for human fertility

genomics more details view paper
  • Downloaded 1,053 times
  • Download rankings, all-time:
    • Site-wide: 22,633
    • In genomics: 2,148
  • Year to date:
    • Site-wide: 113,074
  • Since beginning of last month:
    • Site-wide: 72,707

An epigenome-wide association study of educational attainment (n = 10,767)

genetics more details view paper
  • Downloaded 1,012 times
  • Download rankings, all-time:
    • Site-wide: 23,943
    • In genetics: 1,100
  • Year to date:
    • Site-wide: 100,107
  • Since beginning of last month:
    • Site-wide: 62,177

Genomic and phenomic insights from an atlas of genetic effects on DNA methylation

genetic and genomic medicine more details view paper
  • Downloaded 970 times
  • Download rankings, all-time:
    • Site-wide: 25,542
    • In genetic and genomic medicine: 102
  • Year to date:
    • Site-wide: 8,558
  • Since beginning of last month:
    • Site-wide: 28,478

Personalized Risk Prediction for Type 2 Diabetes: the Potential of Genetic Risk Scores

genetics more details view paper
  • Downloaded 878 times
  • Download rankings, all-time:
    • Site-wide: 29,389
    • In genetics: 1,345
  • Year to date:
    • Site-wide: 90,291
  • Since beginning of last month:
    • Site-wide: None

Identifying tissues implicated in Anorexia Nervosa using Transcriptomic Imputation

genetics more details view paper
  • Downloaded 862 times
  • Download rankings, all-time:
    • Site-wide: 30,158
    • In genetics: 1,394
  • Year to date:
    • Site-wide: 97,828
  • Since beginning of last month:
    • Site-wide: None

An interaction map of circulating metabolites, immune gene networks and their genetic regulation

genomics more details view paper
  • Downloaded 794 times
  • Download rankings, all-time:
    • Site-wide: 33,824
    • In genomics: 2,890
  • Year to date:
    • Site-wide: 114,813
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    • Site-wide: None

Novel blood pressure locus and gene discovery using GWAS and expression datasets from blood and the kidney

genomics more details view paper
  • Downloaded 776 times
  • Download rankings, all-time:
    • Site-wide: 34,956
    • In genomics: 2,957
  • Year to date:
    • Site-wide: 110,580
  • Since beginning of last month:
    • Site-wide: 59,227

Shared Genetic Risk between Eating Disorder- and Substance-Use-Related Phenotypes: Evidence from Genome-Wide Association Studies

genetics more details view paper
  • Downloaded 775 times
  • Download rankings, all-time:
    • Site-wide: 34,988
    • In genetics: 1,594
  • Year to date:
    • Site-wide: 26,074
  • Since beginning of last month:
    • Site-wide: 58,367

Comprehensive population-based genome sequencing provides insight into hematopoietic regulatory mechanisms

genetics more details view paper
  • Downloaded 773 times
  • Download rankings, all-time:
    • Site-wide: 35,130
    • In genetics: 1,600
  • Year to date:
    • Site-wide: 144,380
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    • Site-wide: None

Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries

genomics more details view paper
  • Downloaded 745 times
  • Download rankings, all-time:
    • Site-wide: 36,961
    • In genomics: 3,084
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    • Site-wide: 147,457
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    • Site-wide: None

Constraints on eQTL fine mapping in the presence of multi-site local regulation of gene expression

genetics more details view paper
  • Downloaded 663 times
  • Download rankings, all-time:
    • Site-wide: 43,212
    • In genetics: 1,943
  • Year to date:
    • Site-wide: 142,509
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Advantages of genotype imputation with ethnically matched reference panel for rare variant association analyses

genomics more details view paper
  • Downloaded 641 times
  • Download rankings, all-time:
    • Site-wide: 45,161
    • In genomics: 3,577
  • Year to date:
    • Site-wide: 67,407
  • Since beginning of last month:
    • Site-wide: 65,088

Genome-wide study identifies association between HLA-B*55:01 and penicillin allergy

genetics more details view paper
  • Downloaded 594 times
  • Download rankings, all-time:
    • Site-wide: 49,596
    • In genetics: 2,209
  • Year to date:
    • Site-wide: 80,712
  • Since beginning of last month:
    • Site-wide: 96,293

The effect of X-linked dosage compensation on complex trait variation

genetics more details view paper
  • Downloaded 550 times
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    • Site-wide: 54,659
    • In genetics: 2,417
  • Year to date:
    • Site-wide: 131,462
  • Since beginning of last month:
    • Site-wide: 81,384

Polygenic prediction of breast cancer: comparison of genetic predictors and implications for screening

genetics more details view paper
  • Downloaded 534 times
  • Download rankings, all-time:
    • Site-wide: 56,590
    • In genetics: 2,503
  • Year to date:
    • Site-wide: 118,831
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    • Site-wide: None

Differentially expressed genes reflect disease-induced rather than disease-causing changes in the transcriptome

genetic and genomic medicine more details view paper
  • Downloaded 531 times
  • Download rankings, all-time:
    • Site-wide: 57,043
    • In genetic and genomic medicine: 232
  • Year to date:
    • Site-wide: 31,516
  • Since beginning of last month:
    • Site-wide: 27,422

Multi-ancestry analysis of gene-sleep interactions in 126,926 individuals identifies multiple novel blood lipid loci that contribute to our understanding of sleep-associated adverse blood lipid profile

genomics more details view paper
  • Downloaded 518 times
  • Download rankings, all-time:
    • Site-wide: 58,728
    • In genomics: 4,325
  • Year to date:
    • Site-wide: 141,409
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PAIRUP-MS: Pathway Analysis and Imputation to Relate Unknowns in Profiles from Mass Spectrometry-based metabolite data

bioinformatics more details view paper
  • Downloaded 402 times
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    • Site-wide: 76,627
    • In bioinformatics: 7,149
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    • Site-wide: 141,775
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The landscape of autosomal-recessive pathogenic variants in European populations reveals phenotype-specific effects

genetics more details view paper
  • Downloaded 396 times
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    • Site-wide: 77,651
    • In genetics: 3,386
  • Year to date:
    • Site-wide: 29,245
  • Since beginning of last month:
    • Site-wide: 106,890

Integrating untargeted metabolomics, genetically informed causal inference, and pathway enrichment to define the obesity metabolome

bioinformatics more details view paper
  • Downloaded 373 times
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    • Site-wide: 81,948
    • In bioinformatics: 7,477
  • Year to date:
    • Site-wide: 96,839
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    • Site-wide: 88,726

Search for early pancreatic cancer blood biomarkers in five European prospective population biobanks using metabolomics

epidemiology more details view paper
  • Downloaded 356 times
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    • Site-wide: 85,398
    • In epidemiology: 3,600
  • Year to date:
    • Site-wide: 140,933
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    • Site-wide: 64,065

Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure

genomics more details view paper
  • Downloaded 289 times
  • Download rankings, all-time:
    • Site-wide: 100,202
    • In genomics: 6,065
  • Year to date:
    • Site-wide: 63,162
  • Since beginning of last month:
    • Site-wide: 23,775

Genotype-first approach to the detection of hereditary breast and ovarian cancer risk, and effects of risk disclosure to biobank participants

genetic and genomic medicine more details view paper
  • Downloaded 261 times
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    • Site-wide: 106,717
    • In genetic and genomic medicine: 513
  • Year to date:
    • Site-wide: 53,460
  • Since beginning of last month:
    • Site-wide: 48,125

Genome-wide Screen of Otosclerosis in Population Biobanks: 18 Loci and Shared Heritability with Skeletal Structure

genetic and genomic medicine more details view paper
  • Downloaded 213 times
  • Download rankings, all-time:
    • Site-wide: 118,883
    • In genetic and genomic medicine: 617
  • Year to date:
    • Site-wide: 56,984
  • Since beginning of last month:
    • Site-wide: 49,562

Mendelian randomization identifies the potential causal impact of dietary patterns on circulating blood metabolites

genomics more details view paper
  • Downloaded 189 times
  • Download rankings, all-time:
    • Site-wide: 124,599
    • In genomics: 6,836
  • Year to date:
    • Site-wide: 62,284
  • Since beginning of last month:
    • Site-wide: 40,106

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