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Author: Andres Metspalu

  • ORCiD: http://orcid.org/0000-0002-3718-796X
  • Most recently observed institution: Estonian Genome Center, Institute of Genomics, University of Tartu, Riia 23b, 51010, Tartu, Estonia

Rankings

  • All-time downloads: 69,283 (rank: 2,118 )
  • Categories:
    • bioinformatics: 759 (rank: 19,335 (tie) )
    • epidemiology: 352 (rank: 20,069 (tie) )
    • genetic and genomic medicine: 3,090 (rank: 906 )
    • genetics: 51,866 (rank: 74 )
    • genomics: 10,868 (rank: 1,810 )
    • hiv aids: 1,392 (rank: 70 (tie) )
    • sexual and reproductive health: 956 (rank: 163 (tie) )

Downloads per author, site-wide

Preprints

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

genetics more details view paper
  • Downloaded 9,423 times
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    • Site-wide: 948
    • In genetics: 26
  • Year to date:
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    • Site-wide: 59,670

Genomewide association study identifies 30 loci associated with bipolar disorder

genetics more details view paper
  • Downloaded 7,388 times
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    • Site-wide: 1,295
    • In genetics: 39
  • Year to date:
    • Site-wide: 21,797
  • Since beginning of last month:
    • Site-wide: 27,695

Fine-mapping of an expanded set of type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps

genomics more details view paper
  • Downloaded 3,267 times
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    • Site-wide: 4,018
    • In genomics: 434
  • Year to date:
    • Site-wide: 71,051
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    • Site-wide: 80,014

Genetic analysis of over one million people identifies 535 novel loci for blood pressure.

genetics more details view paper
  • Downloaded 3,110 times
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    • Site-wide: 4,307
    • In genetics: 175
  • Year to date:
    • Site-wide: 61,387
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Improved polygenic prediction by Bayesian multiple regression on summary statistics

genetics more details view paper
  • Downloaded 2,812 times
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    • Site-wide: 4,971
    • In genetics: 211
  • Year to date:
    • Site-wide: 60,365
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    • Site-wide: 38,426

Genome-wide association study identifies 48 common genetic variants associated with handedness

genetics more details view paper
  • Downloaded 2,630 times
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    • Site-wide: 5,460
    • In genetics: 240
  • Year to date:
    • Site-wide: 25,124
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    • Site-wide: 26,484

Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine

genetics more details view paper
  • Downloaded 2,524 times
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    • Site-wide: 5,841
    • In genetics: 256
  • Year to date:
    • Site-wide: 98,344
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    • Site-wide: 70,303

Ultra-rare disruptive and damaging mutations influence educational attainment in the general population

genetics more details view paper
  • Downloaded 2,316 times
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    • Site-wide: 6,622
    • In genetics: 299
  • Year to date:
    • Site-wide: 107,738
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    • Site-wide: 99,103

Widespread signatures of negative selection in the genetic architecture of human complex traits

genetics more details view paper
  • Downloaded 2,300 times
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    • Site-wide: 6,686
    • In genetics: 307
  • Year to date:
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    • Site-wide: 27,673

Cell specific eQTL analysis without sorting cells

genetics more details view paper
  • Downloaded 2,011 times
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    • Site-wide: 8,106
    • In genetics: 362
  • Year to date:
    • Site-wide: 121,062
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    • Site-wide: 117,872

Refining The Accuracy Of Validated Target Identification Through Coding Variant Fine-Mapping In Type 2 Diabetes

genetics more details view paper
  • Downloaded 1,870 times
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    • Site-wide: 9,051
    • In genetics: 407
  • Year to date:
    • Site-wide: 91,357
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A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects

genetics more details view paper
  • Downloaded 1,817 times
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    • Site-wide: 9,465
    • In genetics: 427
  • Year to date:
    • Site-wide: 57,503
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    • Site-wide: 67,900

Genetic Associations with Subjective Well-Being Also Implicate Depression and Neuroticism

genetics more details view paper
  • Downloaded 1,727 times
  • Download rankings, all-time:
    • Site-wide: 10,178
    • In genetics: 468
  • Year to date:
    • Site-wide: 89,812
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    • Site-wide: 96,874

Genome-wide association analyses in >119,000 individuals identifies thirteen morningness and two sleep duration loci

genetics more details view paper
  • Downloaded 1,651 times
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    • Site-wide: 10,885
    • In genetics: 502
  • Year to date:
    • Site-wide: 103,092
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    • Site-wide: 96,996

Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes

genomics more details view paper
  • Downloaded 1,469 times
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    • Site-wide: 12,927
    • In genomics: 1,359
  • Year to date:
    • Site-wide: 93,041
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    • Site-wide: 138,140

A high-resolution HLA reference panel capturing global population diversity enables multi-ethnic fine-mapping in HIV host response

hiv aids more details view paper
  • Downloaded 1,392 times
  • Download rankings, all-time:
    • Site-wide: 14,041
    • In hiv aids: 7
  • Year to date:
    • Site-wide: 5,581
  • Since beginning of last month:
    • Site-wide: 4,666

Trans-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation

genetic and genomic medicine more details view paper
  • Downloaded 1,288 times
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    • Site-wide: 15,763
    • In genetic and genomic medicine: 61
  • Year to date:
    • Site-wide: 6,789
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    • Site-wide: 7,110

Genomic analyses for age at menarche identify 389 independent signals and indicate BMI-independent effects of puberty timing on cancer susceptibility

genomics more details view paper
  • Downloaded 1,256 times
  • Download rankings, all-time:
    • Site-wide: 16,374
    • In genomics: 1,634
  • Year to date:
    • Site-wide: 99,766
  • Since beginning of last month:
    • Site-wide: 99,691

The genetic architecture of sporadic and recurrent miscarriage

genetics more details view paper
  • Downloaded 1,176 times
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    • Site-wide: 18,030
    • In genetics: 857
  • Year to date:
    • Site-wide: 51,502
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    • Site-wide: 59,146

Haplotype sharing provides insights into fine-scale population history and disease in Finland

genetics more details view paper
  • Downloaded 1,142 times
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    • Site-wide: 18,878
    • In genetics: 900
  • Year to date:
    • Site-wide: 72,699
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    • Site-wide: 89,098

Mega-analysis of 31,396 individuals from 6 countries uncovers strong gene-environment interaction for human fertility

genomics more details view paper
  • Downloaded 1,048 times
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    • Site-wide: 21,383
    • In genomics: 2,078
  • Year to date:
    • Site-wide: 97,024
  • Since beginning of last month:
    • Site-wide: 80,590

The Trans-Ancestral Genomic Architecture of Glycaemic Traits

genetics more details view paper
  • Downloaded 1,031 times
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    • Site-wide: 21,923
    • In genetics: 1,026
  • Year to date:
    • Site-wide: 8,296
  • Since beginning of last month:
    • Site-wide: 4,538

An epigenome-wide association study of educational attainment (n = 10,767)

genetics more details view paper
  • Downloaded 1,002 times
  • Download rankings, all-time:
    • Site-wide: 22,850
    • In genetics: 1,071
  • Year to date:
    • Site-wide: 89,678
  • Since beginning of last month:
    • Site-wide: 129,732

Genetic insights into the biological mechanisms governing human ovarian ageing

sexual and reproductive health more details view paper
  • Downloaded 956 times
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    • Site-wide: 24,532
    • In sexual and reproductive health: 14
  • Year to date:
    • Site-wide: 2,369
  • Since beginning of last month:
    • Site-wide: 1,973

Genomic and phenomic insights from an atlas of genetic effects on DNA methylation

genetic and genomic medicine more details view paper
  • Downloaded 874 times
  • Download rankings, all-time:
    • Site-wide: 27,799
    • In genetic and genomic medicine: 100
  • Year to date:
    • Site-wide: 8,185
  • Since beginning of last month:
    • Site-wide: 7,634

Personalized Risk Prediction for Type 2 Diabetes: the Potential of Genetic Risk Scores

genetics more details view paper
  • Downloaded 874 times
  • Download rankings, all-time:
    • Site-wide: 27,791
    • In genetics: 1,307
  • Year to date:
    • Site-wide: 72,841
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    • Site-wide: 80,345

Identifying tissues implicated in Anorexia Nervosa using Transcriptomic Imputation

genetics more details view paper
  • Downloaded 850 times
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    • Site-wide: 28,939
    • In genetics: 1,364
  • Year to date:
    • Site-wide: 89,920
  • Since beginning of last month:
    • Site-wide: 115,517

An interaction map of circulating metabolites, immune gene networks and their genetic regulation

genomics more details view paper
  • Downloaded 786 times
  • Download rankings, all-time:
    • Site-wide: 32,252
    • In genomics: 2,825
  • Year to date:
    • Site-wide: 103,241
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    • Site-wide: 91,294

Comprehensive population-based genome sequencing provides insight into hematopoietic regulatory mechanisms

genetics more details view paper
  • Downloaded 768 times
  • Download rankings, all-time:
    • Site-wide: 33,282
    • In genetics: 1,562
  • Year to date:
    • Site-wide: 134,783
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    • Site-wide: 128,321

Shared Genetic Risk between Eating Disorder- and Substance-Use-Related Phenotypes: Evidence from Genome-Wide Association Studies

genetics more details view paper
  • Downloaded 763 times
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    • Site-wide: 33,619
    • In genetics: 1,569
  • Year to date:
    • Site-wide: 19,801
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    • Site-wide: 88,906

Novel blood pressure locus and gene discovery using GWAS and expression datasets from blood and the kidney

genomics more details view paper
  • Downloaded 760 times
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    • Site-wide: 33,780
    • In genomics: 2,923
  • Year to date:
    • Site-wide: 111,751
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    • Site-wide: 108,497

Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries

genomics more details view paper
  • Downloaded 742 times
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    • Site-wide: 34,957
    • In genomics: 2,992
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    • Site-wide: 136,876
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    • Site-wide: 141,537

Constraints on eQTL fine mapping in the presence of multi-site local regulation of gene expression

genetics more details view paper
  • Downloaded 659 times
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    • Site-wide: 40,997
    • In genetics: 1,895
  • Year to date:
    • Site-wide: 132,353
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    • Site-wide: 99,128

Advantages of genotype imputation with ethnically matched reference panel for rare variant association analyses

genomics more details view paper
  • Downloaded 620 times
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    • Site-wide: 44,254
    • In genomics: 3,558
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    • Site-wide: 62,701
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    • Site-wide: 69,240

Genome-wide study identifies association between HLA-B*55:01 and penicillin allergy

genetics more details view paper
  • Downloaded 585 times
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    • Site-wide: 47,591
    • In genetics: 2,166
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    • Site-wide: 67,722
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    • Site-wide: 93,826

The effect of X-linked dosage compensation on complex trait variation

genetics more details view paper
  • Downloaded 544 times
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    • Site-wide: 52,003
    • In genetics: 2,350
  • Year to date:
    • Site-wide: 120,768
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    • Site-wide: 99,511

Polygenic prediction of breast cancer: comparison of genetic predictors and implications for screening

genetics more details view paper
  • Downloaded 522 times
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    • Site-wide: 54,560
    • In genetics: 2,465
  • Year to date:
    • Site-wide: 115,240
  • Since beginning of last month:
    • Site-wide: 117,610

Multi-ancestry analysis of gene-sleep interactions in 126,926 individuals identifies multiple novel blood lipid loci that contribute to our understanding of sleep-associated adverse blood lipid profile

genomics more details view paper
  • Downloaded 513 times
  • Download rankings, all-time:
    • Site-wide: 55,688
    • In genomics: 4,201
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    • Site-wide: 132,300
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Differentially expressed genes reflect disease-induced rather than disease-causing changes in the transcriptome

genetic and genomic medicine more details view paper
  • Downloaded 494 times
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    • Site-wide: 58,138
    • In genetic and genomic medicine: 222
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PAIRUP-MS: Pathway Analysis and Imputation to Relate Unknowns in Profiles from Mass Spectrometry-based metabolite data

bioinformatics more details view paper
  • Downloaded 400 times
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    • Site-wide: 72,444
    • In bioinformatics: 6,824
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The landscape of autosomal-recessive pathogenic variants in European populations reveals phenotype-specific effects

genetics more details view paper
  • Downloaded 371 times
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    • Site-wide: 77,690
    • In genetics: 3,471
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    • Site-wide: 24,668
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Integrating untargeted metabolomics, genetically informed causal inference, and pathway enrichment to define the obesity metabolome

bioinformatics more details view paper
  • Downloaded 359 times
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    • Site-wide: 79,853
    • In bioinformatics: 7,297
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Search for early pancreatic cancer blood biomarkers in five European prospective population biobanks using metabolomics

epidemiology more details view paper
  • Downloaded 352 times
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    • Site-wide: 81,267
    • In epidemiology: 3,404
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Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure

genomics more details view paper
  • Downloaded 237 times
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    • Site-wide: 106,464
    • In genomics: 6,217
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Genotype-first approach to the detection of hereditary breast and ovarian cancer risk, and effects of risk disclosure to biobank participants

genetic and genomic medicine more details view paper
  • Downloaded 234 times
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    • Site-wide: 107,203
    • In genetic and genomic medicine: 501
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    • Site-wide: 50,314
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    • Site-wide: 21,283

Genome-wide Screen of Otosclerosis in Population Biobanks: 18 Loci and Shared Heritability with Skeletal Structure

genetic and genomic medicine more details view paper
  • Downloaded 200 times
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    • Site-wide: 115,218
    • In genetic and genomic medicine: 575
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    • Site-wide: 47,496
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    • Site-wide: 43,173

Mendelian randomization identifies the potential causal impact of dietary patterns on circulating blood metabolites

genomics more details view paper
  • Downloaded 170 times
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    • Site-wide: 122,294
    • In genomics: 6,711
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    • Site-wide: 55,745
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