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Author: Andres Metspalu

  • ORCiD: http://orcid.org/0000-0002-3718-796X
  • Most recently observed institution: Estonian Genome Center, Institute of Genomics, University of Tartu, Riia 23b, 51010, Tartu, Estonia

Rankings

  • All-time downloads: 65,614 (rank: 1,999 )
  • Categories:
    • bioinformatics: 713 (rank: 18,348 (tie) )
    • epidemiology: 336 (rank: 17,594 (tie) )
    • genetic and genomic medicine: 2,243 (rank: 510 )
    • genetics: 50,301 (rank: 72 )
    • genomics: 10,578 (rank: 1,664 )
    • hiv aids: 973 (rank: 59 (tie) )
    • sexual and reproductive health: 470 (rank: 210 (tie) )

Downloads per author, site-wide

Preprints

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

genetics more details view paper
  • Downloaded 9,364 times
  • Download rankings, all-time:
    • Site-wide: 813
    • In genetics: 25
  • Year to date:
    • Site-wide: 22,256
  • Since beginning of last month:
    • Site-wide: 23,360

Genomewide association study identifies 30 loci associated with bipolar disorder

genetics more details view paper
  • Downloaded 7,266 times
  • Download rankings, all-time:
    • Site-wide: 1,128
    • In genetics: 38
  • Year to date:
    • Site-wide: 15,434
  • Since beginning of last month:
    • Site-wide: 11,948

Fine-mapping of an expanded set of type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps

genomics more details view paper
  • Downloaded 3,223 times
  • Download rankings, all-time:
    • Site-wide: 3,496
    • In genomics: 397
  • Year to date:
    • Site-wide: 66,987
  • Since beginning of last month:
    • Site-wide: 47,002

Genetic analysis of over one million people identifies 535 novel loci for blood pressure.

genetics more details view paper
  • Downloaded 3,069 times
  • Download rankings, all-time:
    • Site-wide: 3,736
    • In genetics: 166
  • Year to date:
    • Site-wide: 37,943
  • Since beginning of last month:
    • Site-wide: 48,112

Improved polygenic prediction by Bayesian multiple regression on summary statistics

genetics more details view paper
  • Downloaded 2,748 times
  • Download rankings, all-time:
    • Site-wide: 4,348
    • In genetics: 201
  • Year to date:
    • Site-wide: 89,327
  • Since beginning of last month:
    • Site-wide: None

Genome-wide association study identifies 48 common genetic variants associated with handedness

genetics more details view paper
  • Downloaded 2,526 times
  • Download rankings, all-time:
    • Site-wide: 4,923
    • In genetics: 229
  • Year to date:
    • Site-wide: 16,455
  • Since beginning of last month:
    • Site-wide: 15,826

Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine

genetics more details view paper
  • Downloaded 2,501 times
  • Download rankings, all-time:
    • Site-wide: 5,018
    • In genetics: 231
  • Year to date:
    • Site-wide: 71,319
  • Since beginning of last month:
    • Site-wide: 74,333

Ultra-rare disruptive and damaging mutations influence educational attainment in the general population

genetics more details view paper
  • Downloaded 2,294 times
  • Download rankings, all-time:
    • Site-wide: 5,709
    • In genetics: 272
  • Year to date:
    • Site-wide: 92,984
  • Since beginning of last month:
    • Site-wide: 58,168

Widespread signatures of negative selection in the genetic architecture of human complex traits

genetics more details view paper
  • Downloaded 2,208 times
  • Download rankings, all-time:
    • Site-wide: 6,032
    • In genetics: 293
  • Year to date:
    • Site-wide: 66,699
  • Since beginning of last month:
    • Site-wide: 46,902

Cell specific eQTL analysis without sorting cells

genetics more details view paper
  • Downloaded 1,995 times
  • Download rankings, all-time:
    • Site-wide: 6,947
    • In genetics: 340
  • Year to date:
    • Site-wide: 96,177
  • Since beginning of last month:
    • Site-wide: 80,231

Refining The Accuracy Of Validated Target Identification Through Coding Variant Fine-Mapping In Type 2 Diabetes

genetics more details view paper
  • Downloaded 1,826 times
  • Download rankings, all-time:
    • Site-wide: 7,952
    • In genetics: 387
  • Year to date:
    • Site-wide: None
  • Since beginning of last month:
    • Site-wide: None

A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects

genetics more details view paper
  • Downloaded 1,772 times
  • Download rankings, all-time:
    • Site-wide: 8,325
    • In genetics: 407
  • Year to date:
    • Site-wide: 35,947
  • Since beginning of last month:
    • Site-wide: 35,315

Genetic Associations with Subjective Well-Being Also Implicate Depression and Neuroticism

genetics more details view paper
  • Downloaded 1,704 times
  • Download rankings, all-time:
    • Site-wide: 8,858
    • In genetics: 440
  • Year to date:
    • Site-wide: 54,830
  • Since beginning of last month:
    • Site-wide: 52,487

Genome-wide association analyses in >119,000 individuals identifies thirteen morningness and two sleep duration loci

genetics more details view paper
  • Downloaded 1,634 times
  • Download rankings, all-time:
    • Site-wide: 9,452
    • In genetics: 467
  • Year to date:
    • Site-wide: 61,907
  • Since beginning of last month:
    • Site-wide: 39,295

Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes

genomics more details view paper
  • Downloaded 1,447 times
  • Download rankings, all-time:
    • Site-wide: 11,270
    • In genomics: 1,255
  • Year to date:
    • Site-wide: 58,962
  • Since beginning of last month:
    • Site-wide: 52,540

Genomic analyses for age at menarche identify 389 independent signals and indicate BMI-independent effects of puberty timing on cancer susceptibility

genomics more details view paper
  • Downloaded 1,240 times
  • Download rankings, all-time:
    • Site-wide: 14,210
    • In genomics: 1,513
  • Year to date:
    • Site-wide: 54,719
  • Since beginning of last month:
    • Site-wide: 41,189

The genetic architecture of sporadic and recurrent miscarriage

genetics more details view paper
  • Downloaded 1,112 times
  • Download rankings, all-time:
    • Site-wide: 16,787
    • In genetics: 853
  • Year to date:
    • Site-wide: 47,950
  • Since beginning of last month:
    • Site-wide: 26,572

Haplotype sharing provides insights into fine-scale population history and disease in Finland

genetics more details view paper
  • Downloaded 1,102 times
  • Download rankings, all-time:
    • Site-wide: 17,020
    • In genetics: 867
  • Year to date:
    • Site-wide: 61,450
  • Since beginning of last month:
    • Site-wide: 49,693

Mega-analysis of 31,396 individuals from 6 countries uncovers strong gene-environment interaction for human fertility

genomics more details view paper
  • Downloaded 1,023 times
  • Download rankings, all-time:
    • Site-wide: 19,010
    • In genomics: 1,951
  • Year to date:
    • Site-wide: 76,071
  • Since beginning of last month:
    • Site-wide: 104,249

Trans-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation

genetic and genomic medicine more details view paper
  • Downloaded 980 times
  • Download rankings, all-time:
    • Site-wide: 20,217
    • In genetic and genomic medicine: 61
  • Year to date:
    • Site-wide: 6,473
  • Since beginning of last month:
    • Site-wide: 6,351

An epigenome-wide association study of educational attainment (n = 10,767)

genetics more details view paper
  • Downloaded 979 times
  • Download rankings, all-time:
    • Site-wide: 20,249
    • In genetics: 1,004
  • Year to date:
    • Site-wide: 54,797
  • Since beginning of last month:
    • Site-wide: 64,608

A high-resolution HLA reference panel capturing global population diversity enables multi-ethnic fine-mapping in HIV host response

hiv aids more details view paper
  • Downloaded 973 times
  • Download rankings, all-time:
    • Site-wide: 20,417
    • In hiv aids: 8
  • Year to date:
    • Site-wide: 10,802
  • Since beginning of last month:
    • Site-wide: 7,718

Personalized Risk Prediction for Type 2 Diabetes: the Potential of Genetic Risk Scores

genetics more details view paper
  • Downloaded 836 times
  • Download rankings, all-time:
    • Site-wide: 25,338
    • In genetics: 1,255
  • Year to date:
    • Site-wide: 54,826
  • Since beginning of last month:
    • Site-wide: 35,318

Identifying tissues implicated in Anorexia Nervosa using Transcriptomic Imputation

genetics more details view paper
  • Downloaded 825 times
  • Download rankings, all-time:
    • Site-wide: 25,843
    • In genetics: 1,286
  • Year to date:
    • Site-wide: 61,499
  • Since beginning of last month:
    • Site-wide: 60,090

An interaction map of circulating metabolites, immune gene networks and their genetic regulation

genomics more details view paper
  • Downloaded 759 times
  • Download rankings, all-time:
    • Site-wide: 29,016
    • In genomics: 2,671
  • Year to date:
    • Site-wide: 104,841
  • Since beginning of last month:
    • Site-wide: 75,372

Comprehensive population-based genome sequencing provides insight into hematopoietic regulatory mechanisms

genetics more details view paper
  • Downloaded 755 times
  • Download rankings, all-time:
    • Site-wide: 29,259
    • In genetics: 1,452
  • Year to date:
    • Site-wide: 119,268
  • Since beginning of last month:
    • Site-wide: 74,463

Novel blood pressure locus and gene discovery using GWAS and expression datasets from blood and the kidney

genomics more details view paper
  • Downloaded 746 times
  • Download rankings, all-time:
    • Site-wide: 29,726
    • In genomics: 2,720
  • Year to date:
    • Site-wide: 69,284
  • Since beginning of last month:
    • Site-wide: 66,339

Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries

genomics more details view paper
  • Downloaded 737 times
  • Download rankings, all-time:
    • Site-wide: 30,205
    • In genomics: 2,754
  • Year to date:
    • Site-wide: 90,028
  • Since beginning of last month:
    • Site-wide: 78,811

The Trans-Ancestral Genomic Architecture of Glycaemic Traits

genetics more details view paper
  • Downloaded 711 times
  • Download rankings, all-time:
    • Site-wide: 31,775
    • In genetics: 1,578
  • Year to date:
    • Site-wide: 14,335
  • Since beginning of last month:
    • Site-wide: 10,256

Constraints on eQTL fine mapping in the presence of multi-site local regulation of gene expression

genetics more details view paper
  • Downloaded 647 times
  • Download rankings, all-time:
    • Site-wide: 36,080
    • In genetics: 1,766
  • Year to date:
    • Site-wide: 108,400
  • Since beginning of last month:
    • Site-wide: 74,509

Shared Genetic Risk between Eating Disorder- and Substance-Use-Related Phenotypes: Evidence from Genome-Wide Association Studies

genetics more details view paper
  • Downloaded 633 times
  • Download rankings, all-time:
    • Site-wide: 37,107
    • In genetics: 1,813
  • Year to date:
    • Site-wide: 14,113
  • Since beginning of last month:
    • Site-wide: 5,254

Genomic and phenomic insights from an atlas of genetic effects on DNA methylation

genetic and genomic medicine more details view paper
  • Downloaded 602 times
  • Download rankings, all-time:
    • Site-wide: 39,536
    • In genetic and genomic medicine: 113
  • Year to date:
    • Site-wide: 7,852
  • Since beginning of last month:
    • Site-wide: 10,843

Advantages of genotype imputation with ethnically matched reference panel for rare variant association analyses

genomics more details view paper
  • Downloaded 576 times
  • Download rankings, all-time:
    • Site-wide: 41,782
    • In genomics: 3,451
  • Year to date:
    • Site-wide: 43,544
  • Since beginning of last month:
    • Site-wide: 30,068

Genome-wide study identifies association between HLA-B*55:01 and penicillin allergy

genetics more details view paper
  • Downloaded 551 times
  • Download rankings, all-time:
    • Site-wide: 44,227
    • In genetics: 2,133
  • Year to date:
    • Site-wide: 38,617
  • Since beginning of last month:
    • Site-wide: 46,519

The effect of X-linked dosage compensation on complex trait variation

genetics more details view paper
  • Downloaded 523 times
  • Download rankings, all-time:
    • Site-wide: 47,036
    • In genetics: 2,254
  • Year to date:
    • Site-wide: 118,843
  • Since beginning of last month:
    • Site-wide: 78,003

Polygenic prediction of breast cancer: comparison of genetic predictors and implications for screening

genetics more details view paper
  • Downloaded 507 times
  • Download rankings, all-time:
    • Site-wide: 48,723
    • In genetics: 2,327
  • Year to date:
    • Site-wide: 81,476
  • Since beginning of last month:
    • Site-wide: 65,110

Multi-ancestry analysis of gene-sleep interactions in 126,926 individuals identifies multiple novel blood lipid loci that contribute to our understanding of sleep-associated adverse blood lipid profile

genomics more details view paper
  • Downloaded 501 times
  • Download rankings, all-time:
    • Site-wide: 49,473
    • In genomics: 3,916
  • Year to date:
    • Site-wide: 107,853
  • Since beginning of last month:
    • Site-wide: 95,163

Genetic insights into the biological mechanisms governing human ovarian ageing

sexual and reproductive health more details view paper
  • Downloaded 470 times
  • Download rankings, all-time:
    • Site-wide: 53,148
    • In sexual and reproductive health: 20
  • Year to date:
    • Site-wide: 1,336
  • Since beginning of last month:
    • Site-wide: 1,401

PAIRUP-MS: Pathway Analysis and Imputation to Relate Unknowns in Profiles from Mass Spectrometry-based metabolite data

bioinformatics more details view paper
  • Downloaded 387 times
  • Download rankings, all-time:
    • Site-wide: 64,938
    • In bioinformatics: 6,325
  • Year to date:
    • Site-wide: 96,690
  • Since beginning of last month:
    • Site-wide: 77,068

Differentially expressed genes reflect disease-induced rather than disease-causing changes in the transcriptome

genetic and genomic medicine more details view paper
  • Downloaded 382 times
  • Download rankings, all-time:
    • Site-wide: 65,720
    • In genetic and genomic medicine: 195
  • Year to date:
    • Site-wide: 28,270
  • Since beginning of last month:
    • Site-wide: 32,944

Search for early pancreatic cancer blood biomarkers in five European prospective population biobanks using metabolomics

epidemiology more details view paper
  • Downloaded 336 times
  • Download rankings, all-time:
    • Site-wide: 73,483
    • In epidemiology: 3,033
  • Year to date:
    • Site-wide: 116,602
  • Since beginning of last month:
    • Site-wide: 95,410

Integrating untargeted metabolomics, genetically informed causal inference, and pathway enrichment to define the obesity metabolome

bioinformatics more details view paper
  • Downloaded 326 times
  • Download rankings, all-time:
    • Site-wide: 75,307
    • In bioinformatics: 7,010
  • Year to date:
    • Site-wide: 93,904
  • Since beginning of last month:
    • Site-wide: 105,456

The landscape of autosomal-recessive pathogenic variants in European populations reveals phenotype-specific effects

genetics more details view paper
  • Downloaded 213 times
  • Download rankings, all-time:
    • Site-wide: 98,897
    • In genetics: 4,468
  • Year to date:
    • Site-wide: 56,314
  • Since beginning of last month:
    • Site-wide: 56,161

Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure

genomics more details view paper
  • Downloaded 199 times
  • Download rankings, all-time:
    • Site-wide: 101,916
    • In genomics: 6,014
  • Year to date:
    • Site-wide: 99,026
  • Since beginning of last month:
    • Site-wide: 100,787

Genotype-first approach to the detection of hereditary breast and ovarian cancer risk, and effects of risk disclosure to biobank participants

genetic and genomic medicine more details view paper
  • Downloaded 156 times
  • Download rankings, all-time:
    • Site-wide: 110,724
    • In genetic and genomic medicine: 470
  • Year to date:
    • Site-wide: 74,832
  • Since beginning of last month:
    • Site-wide: 85,313

Mendelian randomization identifies the potential causal impact of dietary patterns on circulating blood metabolites

genomics more details view paper
  • Downloaded 127 times
  • Download rankings, all-time:
    • Site-wide: 116,184
    • In genomics: 6,436
  • Year to date:
    • Site-wide: 31,487
  • Since beginning of last month:
    • Site-wide: None

Genome-wide Screen of Otosclerosis in Population Biobanks: 18 Loci and Shared Heritability with Skeletal Structure

genetic and genomic medicine more details view paper
  • Downloaded 123 times
  • Download rankings, all-time:
    • Site-wide: 116,876
    • In genetic and genomic medicine: 519
  • Year to date:
    • Site-wide: 56,026
  • Since beginning of last month:
    • Site-wide: 68,250

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