Author: Reedik Magi

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Preprints

Global biobank analyses provide lessons for computing polygenic risk scores across diverse cohorts

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Genome-wide association analysis of lifetime cannabis use (N=184,765) identifies new risk loci, genetic overlap with mental health, and a causal influence of schizophrenia on cannabis use

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Fine-mapping of an expanded set of type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps

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Genetic analysis of over one million people identifies 535 novel loci for blood pressure.

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Genomic evaluation of circulating proteins for drug target characterisation and precision medicine

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Ultra-rare disruptive and damaging mutations influence educational attainment in the general population

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Refining The Accuracy Of Validated Target Identification Through Coding Variant Fine-Mapping In Type 2 Diabetes

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PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

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Lifelong genetically lowered sclerostin and risk of cardiovascular disease.

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Genomic analyses for age at menarche identify 389 independent signals and indicate BMI-independent effects of puberty timing on cancer susceptibility

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The genetic architecture of sporadic and recurrent miscarriage

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The Trans-Ancestral Genomic Architecture of Glycaemic Traits

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Translating genotype data of 44,000 biobank participants into clinical pharmacogenetic recommendations: challenges and solutions

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Causal relationships between obesity and the leading causes of death in women and men

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Endometrial receptivity revisited: endometrial transcriptome adjusted for tissue cellular heterogeneity

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GWAS identifies novel risk locus for erectile dysfunction and implicates hypothalamic neurobiology and diabetes in etiology

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Personalized Risk Prediction for Type 2 Diabetes: the Potential of Genetic Risk Scores

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Comprehensive population-based genome sequencing provides insight into hematopoietic regulatory mechanisms

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Genome-wide association study identifies five risk loci for pernicious anemia and implicates the role of HLA-DR15 haplotype

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The individual and global impact of copy number variants on complex human traits

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Advantages of genotype imputation with ethnically matched reference panel for rare variant association analyses

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GWAS meta-analysis highlights the hypothalamic-pituitary-gonadal axis (HPG axis) in the genetic regulation of menstrual cycle length

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Genome-wide study identifies association between HLA-B*55:01 and penicillin allergy

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The complement system supports normal postnatal development and gonadal function in both sexes

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Analytical strategies to include the X-chromosome in variance heterogeneity analyses: evidence for trait-specific polygenic variance structure

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Polygenic prediction of breast cancer: comparison of genetic predictors and implications for screening

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Multi-ancestry analysis of gene-sleep interactions in 126,926 individuals identifies multiple novel blood lipid loci that contribute to our understanding of sleep-associated adverse blood lipid profile

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Random glucose GWAS in 493,036 individuals provides insights into diabetes pathophysiology, complications and treatment stratification

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Leveraging biobank-scale rare and common variant analyses to identify ASPHD1 as the main driver of reproductive traits in the 16p11.2 locus

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Improving GWAS discovery and genomic prediction accuracy in Biobank data

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Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure

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Genetics of fasting indices of glucose homeostasis using GWIS unravels tight relationships with inflammatory markers

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Genetic analysis of obstructive sleep apnoea discovers a strong association with cardiometabolic health

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Genome-wide Screen of Otosclerosis in Population Biobanks: 18 Loci and Shared Heritability with Skeletal Structure

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Advancing our understanding of genetic risk factors and potential personalized strategies in pelvic organ prolapse: largest GWAS to date reveals 19 novel associated loci

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GWAS meta-analysis and gene expression data link reproductive tract development, immune response and cellular proliferation/apoptosis with cervical cancer and clarify overlap with other cervical phenotypes

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