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Author: Diether Lambrechts

Rankings

  • All-time downloads: 29,195 (rank: 9,962 )
  • Categories:
    • cancer biology: 11,391 (rank: 262 )
    • developmental biology: 348 (rank: 22,664 (tie) )
    • epidemiology: 439 (rank: 29,429 (tie) )
    • genetic and genomic medicine: 389 (rank: 15,274 (tie) )
    • genetics: 5,224 (rank: 4,793 (tie) )
    • genomics: 2,814 (rank: 11,937 )
    • immunology: 5,449 (rank: 3,232 (tie) )
    • infectious diseases: 1,138 (rank: 35,783 (tie) )
    • molecular biology: 227 (rank: 37,186 (tie) )
    • oncology: 858 (rank: 1,896 )
    • transplantation: 334 (rank: 574 (tie) )

Downloads per author, site-wide

Preprints

Discriminating Mild from Critical COVID-19 by Innate and Adaptive Immune Single-cell Profiling of Bronchoalveolar Lavages

immunology more details view paper
  • Downloaded 3,193 times
  • Download rankings, all-time:
    • Site-wide: 6,692
    • In immunology: 269
  • Year to date:
    • Site-wide: 37,956
  • Since beginning of last month:
    • Site-wide: 30,633

A Pan-Cancer Blueprint of the Heterogeneous Tumour Microenvironment Revealed by Single-Cell Profiling

cancer biology more details view paper
  • Downloaded 1,992 times
  • Download rankings, all-time:
    • Site-wide: 13,518
    • In cancer biology: 270
  • Year to date:
    • Site-wide: 39,755
  • Since beginning of last month:
    • Site-wide: 66,203

Fine-mapping of 150 breast cancer risk regions identifies 178 high confidence target genes

genetics more details view paper
  • Downloaded 1,909 times
  • Download rankings, all-time:
    • Site-wide: 14,423
    • In genetics: 566
  • Year to date:
    • Site-wide: 158,193
  • Since beginning of last month:
    • Site-wide: 180,645

Heterogeneity in PHGDH protein expression potentiates cancer cell dissemination and metastasis

cancer biology more details view paper
  • Downloaded 1,835 times
  • Download rankings, all-time:
    • Site-wide: 15,341
    • In cancer biology: 325
  • Year to date:
    • Site-wide: 11,506
  • Since beginning of last month:
    • Site-wide: 33,390

Genomic analyses for age at menarche identify 389 independent signals and indicate BMI-independent effects of puberty timing on cancer susceptibility

genomics more details view paper
  • Downloaded 1,412 times
  • Download rankings, all-time:
    • Site-wide: 23,227
    • In genomics: 2,011
  • Year to date:
    • Site-wide: 87,824
  • Since beginning of last month:
    • Site-wide: 174,821

Immunogenomic, single-cell and spatial dissection of CD8+T cell exhaustion reveals critical determinants of cancer immunotherapy

immunology more details view paper
  • Downloaded 1,379 times
  • Download rankings, all-time:
    • Site-wide: 24,113
    • In immunology: 914
  • Year to date:
    • Site-wide: 9,842
  • Since beginning of last month:
    • Site-wide: 19,889

Anticancer immunotherapies transition postcapillary venules into high-endothelial venules that generate TCF1+ T lymphocyte niches through a feed-forward loop

cancer biology more details view paper
  • Downloaded 1,262 times
  • Download rankings, all-time:
    • Site-wide: 27,765
    • In cancer biology: 719
  • Year to date:
    • Site-wide: 33,756
  • Since beginning of last month:
    • Site-wide: 16,697

A TCF4/BRD4-dependent regulatory network confers cross-resistance to targeted and immune checkpoint therapy in melanoma

cancer biology more details view paper
  • Downloaded 1,182 times
  • Download rankings, all-time:
    • Site-wide: 30,794
    • In cancer biology: 934
  • Year to date:
    • Site-wide: 2,300
  • Since beginning of last month:
    • Site-wide: 2,197

Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses

genetics more details view paper
  • Downloaded 1,168 times
  • Download rankings, all-time:
    • Site-wide: 31,381
    • In genetics: 1,255
  • Year to date:
    • Site-wide: 79,338
  • Since beginning of last month:
    • Site-wide: 127,851

Clinical practices underlie COVID-19 patient respiratory microbiome composition and its interactions with the host

infectious diseases more details view paper
  • Downloaded 1,145 times
  • Download rankings, all-time:
    • Site-wide: 32,359
    • In infectious diseases: 2,968
  • Year to date:
    • Site-wide: 94,131
  • Since beginning of last month:
    • Site-wide: 113,866

Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts

cancer biology more details view paper
  • Downloaded 1,054 times
  • Download rankings, all-time:
    • Site-wide: 36,745
    • In cancer biology: 995
  • Year to date:
    • Site-wide: 116,760
  • Since beginning of last month:
    • Site-wide: 164,396

Combining genome-wide studies of breast, prostate, ovarian and endometrial cancers maps cross-cancer susceptibility loci and identifies new genetic associations

genetics more details view paper
  • Downloaded 942 times
  • Download rankings, all-time:
    • Site-wide: 43,752
    • In genetics: 1,747
  • Year to date:
    • Site-wide: 29,981
  • Since beginning of last month:
    • Site-wide: 39,038

Common variants in breast cancer risk loci predispose to distinct tumor subtypes

genetics more details view paper
  • Downloaded 928 times
  • Download rankings, all-time:
    • Site-wide: 44,729
    • In genetics: 1,757
  • Year to date:
    • Site-wide: 151,699
  • Since beginning of last month:
    • Site-wide: 140,866

In vivo CRISPR screen defines Slc25a37 as an organ-specific regulator of antioxidant metabolism in metastasis

cancer biology more details view paper
  • Downloaded 821 times
  • Download rankings, all-time:
    • Site-wide: 53,949
    • In cancer biology: 1,689
  • Year to date:
    • Site-wide: 3,641
  • Since beginning of last month:
    • Site-wide: 3,357

A multi-layered systems approach for renal cell carcinoma

cancer biology more details view paper
  • Downloaded 813 times
  • Download rankings, all-time:
    • Site-wide: 54,759
    • In cancer biology: 1,590
  • Year to date:
    • Site-wide: 63,661
  • Since beginning of last month:
    • Site-wide: 78,919

Emerging single cell endothelial heterogeneity supports sprouting tumour angiogenesis and growth

cancer biology more details view paper
  • Downloaded 783 times
  • Download rankings, all-time:
    • Site-wide: 57,793
    • In cancer biology: 1,775
  • Year to date:
    • Site-wide: 11,814
  • Since beginning of last month:
    • Site-wide: 15,887

A neural crest stem cell-like state drives nongenetic resistance to targeted therapy in melanoma

cancer biology more details view paper
  • Downloaded 779 times
  • Download rankings, all-time:
    • Site-wide: 58,275
    • In cancer biology: 1,737
  • Year to date:
    • Site-wide: 29,942
  • Since beginning of last month:
    • Site-wide: 71,071

DNA Methylation Repels Binding of HIF Transcription Factors to Maintain Tumour Immunotolerance

genomics more details view paper
  • Downloaded 770 times
  • Download rankings, all-time:
    • Site-wide: 59,331
    • In genomics: 4,176
  • Year to date:
    • Site-wide: 135,335
  • Since beginning of last month:
    • Site-wide: 101,399

The tumor suppressor protein PTEN undergoes amyloid-like aggregation in tumor cells.

cancer biology more details view paper
  • Downloaded 655 times
  • Download rankings, all-time:
    • Site-wide: 74,685
    • In cancer biology: 2,295
  • Year to date:
    • Site-wide: 7,703
  • Since beginning of last month:
    • Site-wide: 17,006

Shared heritability and functional enrichment across six solid cancers

genomics more details view paper
  • Downloaded 649 times
  • Download rankings, all-time:
    • Site-wide: 75,530
    • In genomics: 5,012
  • Year to date:
    • Site-wide: 161,516
  • Since beginning of last month:
    • Site-wide: 145,355

Inflammasome- and gasdermin D-independent IL-1β production mobilizes neutrophils to inhibit antitumor immunity

immunology more details view paper
  • Downloaded 525 times
  • Download rankings, all-time:
    • Site-wide: 98,608
    • In immunology: 3,208
  • Year to date:
    • Site-wide: 38,028
  • Since beginning of last month:
    • Site-wide: 161,406

Cross-cancer genome-wide association study of endometrial cancer and epithelial ovarian cancer identifies genetic risk regions associated with risk of both cancers

oncology more details view paper
  • Downloaded 521 times
  • Download rankings, all-time:
    • Site-wide: 99,344
    • In oncology: 233
  • Year to date:
    • Site-wide: 190,267
  • Since beginning of last month:
    • Site-wide: 104,424

Polygenic Risk Modelling for Prediction of Epithelial Ovarian Cancer Risk

epidemiology more details view paper
  • Downloaded 446 times
  • Download rankings, all-time:
    • Site-wide: 117,399
    • In epidemiology: 4,959
  • Year to date:
    • Site-wide: 127,229
  • Since beginning of last month:
    • Site-wide: 113,934

Targeting C5aR1 signaling reduced neutrophil extracellular traps and ameliorates COVID-19 pathology

immunology more details view paper
  • Downloaded 427 times
  • Download rankings, all-time:
    • Site-wide: 122,524
    • In immunology: 4,046
  • Year to date:
    • Site-wide: 19,997
  • Since beginning of last month:
    • Site-wide: 32,236

A palmitate-rich metastatic niche enables metastasis growth via p65 acetylation

cancer biology more details view paper
  • Downloaded 423 times
  • Download rankings, all-time:
    • Site-wide: 123,327
    • In cancer biology: 4,053
  • Year to date:
    • Site-wide: 6,389
  • Since beginning of last month:
    • Site-wide: 3,709

Pan-cancer detection and typing by mining patterns in large genome-wide cell-free DNA sequencing datasets

genetic and genomic medicine more details view paper
  • Downloaded 403 times
  • Download rankings, all-time:
    • Site-wide: 129,194
    • In genetic and genomic medicine: 906
  • Year to date:
    • Site-wide: 33,363
  • Since beginning of last month:
    • Site-wide: 41,922

Transcriptional and spatial profiling of the kidney allograft unravels a central role for FcRγIII+ innate immune cells in rejection

transplantation more details view paper
  • Downloaded 364 times
  • Download rankings, all-time:
    • Site-wide: 140,706
    • In transplantation: 61
  • Year to date:
    • Site-wide: 8,624
  • Since beginning of last month:
    • Site-wide: 14,299

Decoding the activated stem cell phenotype of the vividly maturing neonatal pituitary

developmental biology more details view paper
  • Downloaded 355 times
  • Download rankings, all-time:
    • Site-wide: 143,343
    • In developmental biology: 3,830
  • Year to date:
    • Site-wide: 73,572
  • Since beginning of last month:
    • Site-wide: 87,620

Multi-tissue transcriptome-wide association study identifies genetic mechanisms underlying endometrial cancer susceptibility

oncology more details view paper
  • Downloaded 343 times
  • Download rankings, all-time:
    • Site-wide: 146,885
    • In oncology: 477
  • Year to date:
    • Site-wide: 125,713
  • Since beginning of last month:
    • Site-wide: 132,713

Rare copy number variants (CNVs) and breast cancer risk

genetics more details view paper
  • Downloaded 315 times
  • Download rankings, all-time:
    • Site-wide: 155,334
    • In genetics: 5,801
  • Year to date:
    • Site-wide: 74,755
  • Since beginning of last month:
    • Site-wide: 98,232

The RNA demethylase FTO controls m6A marking on SARS-CoV-2 and classifies COVID-19 severity in patients

molecular biology more details view paper
  • Downloaded 233 times
  • Download rankings, all-time:
    • Site-wide: 179,183
    • In molecular biology: 5,406
  • Year to date:
    • Site-wide: 109,624
  • Since beginning of last month:
    • Site-wide: 46,696

Identification and characterization of four bacteriome- and mycobiome-derived subtypes in tumour and adjacent mucosa tissue of colorectal cancer patients

cancer biology more details view paper
  • Downloaded 123 times
  • Download rankings, all-time:
    • Site-wide: 203,290
    • In cancer biology: 6,377
  • Year to date:
    • Site-wide: 22,695
  • Since beginning of last month:
    • Site-wide: 42,263

Intermediate molecular phenotypes to identify genetic markers of anthracycline-induced cardiotoxicity risk

genetics more details view paper
  • Downloaded 46 times
  • Download rankings, all-time:
    • Site-wide: 216,193
    • In genetics: None
  • Year to date:
    • Site-wide: 3,075
  • Since beginning of last month:
    • Site-wide: None

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