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Author: Hermann Brenner

Rankings

  • All-time downloads: 19,200 (rank: 11,007 )
  • Categories:
    • bioinformatics: 327 (rank: 34,226 (tie) )
    • cancer biology: 216 (rank: 33,330 (tie) )
    • epidemiology: 4,470 (rank: 3,269 )
    • gastroenterology: 1,157 (rank: 223 (tie) )
    • genetic and genomic medicine: 931 (rank: 3,917 (tie) )
    • genetics: 8,818 (rank: 2,080 )
    • genomics: 3,281 (rank: 7,927 (tie) )

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Preprints

Long-term low-dose acetylsalicylic use shows protective potential for the development of both vascular dementia and Alzheimer's disease in patients with coronary heart disease but not in other individuals from the general population: results from two large cohort studies

epidemiology more details view paper

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Making colonoscopy-based screening more efficient: a "gateopener" approach

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Pan-cancer image-based detection of clinically actionable genetic alterations

genetics more details view paper
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    • In genetics: 299
  • Year to date:
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Fine-mapping of 150 breast cancer risk regions identifies 178 high confidence target genes

genetics more details view paper
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    • Site-wide: 10,802
    • In genetics: 475
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Vitamin D insufficiency and deficiency and mortality from respiratory diseases in a cohort of older adults: potential for limiting the death toll during and beyond the COVID-19 pandemic

epidemiology more details view paper
  • Downloaded 1,687 times
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Epigenome-wide association meta-analysis of DNA methylation with coffee and tea consumption

genomics more details view paper
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    • In genomics: 1,483
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Genomic analyses for age at menarche identify 389 independent signals and indicate BMI-independent effects of puberty timing on cancer susceptibility

genomics more details view paper
  • Downloaded 1,291 times
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    • Site-wide: 17,141
    • In genomics: 1,677
  • Year to date:
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A genetic risk score to guide age-specific, personalized prostate cancer screening

genetics more details view paper
  • Downloaded 964 times
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    • Site-wide: 26,321
    • In genetics: 1,206
  • Year to date:
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Winners curse correction and variable thresholding improve performance of polygenic risk modeling based on summary-level data from genome-wide association studies

genetics more details view paper
  • Downloaded 954 times
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Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses

genetics more details view paper
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    • Site-wide: 28,550
    • In genetics: 1,305
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BRAF mutation testing of MSI CRCs in Lynch syndrome diagnostics: performance and efficiency according to patient`s age

gastroenterology more details view paper
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    • Site-wide: 40,544
    • In gastroenterology: 39
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Common variants in breast cancer risk loci predispose to distinct tumor subtypes

genetics more details view paper
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    • Site-wide: 47,566
    • In genetics: 2,121
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Evaluation of different stool extraction methods for metabolomics measurements in human fecal samples

epidemiology more details view paper
  • Downloaded 589 times
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    • Site-wide: 51,304
    • In epidemiology: 2,407
  • Year to date:
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Shared heritability and functional enrichment across six solid cancers

genomics more details view paper
  • Downloaded 557 times
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    • Site-wide: 55,113
    • In genomics: 4,139
  • Year to date:
    • Site-wide: 127,289
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Polygenic hazard score predicts aggressive and fatal prostate cancer in multi-ethnic populations

genetic and genomic medicine more details view paper
  • Downloaded 484 times
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    • Site-wide: 64,693
    • In genetic and genomic medicine: 269
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    • Site-wide: 63,518
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Colonoscopy and reduction of colorectal cancer risk by molecular tumor subtypes: a population-based case-control study

gastroenterology more details view paper
  • Downloaded 449 times
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    • Site-wide: 70,129
    • In gastroenterology: 68
  • Year to date:
    • Site-wide: 52,091
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    • Site-wide: 66,758

Physical activity and risks of breast and colorectal cancer: A Mendelian randomization analysis

genetics more details view paper
  • Downloaded 390 times
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    • Site-wide: 80,635
    • In genetics: 3,500
  • Year to date:
    • Site-wide: 143,896
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    • Site-wide: 71,082

A genetic hazard score to personalize prostate cancer screening, applied to population data

genetics more details view paper
  • Downloaded 386 times
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    • Site-wide: 81,363
    • In genetics: 3,530
  • Year to date:
    • Site-wide: 149,535
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    • Site-wide: None

Adiposity, metabolites, and colorectal cancer risk: Mendelian randomization study

epidemiology more details view paper
  • Downloaded 382 times
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    • Site-wide: 82,125
    • In epidemiology: 3,507
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    • Site-wide: 100,420
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    • Site-wide: 135,815

Benchmarking artificial intelligence methods for end-to-end computational pathology

bioinformatics more details view paper
  • Downloaded 327 times
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    • Site-wide: 93,631
    • In bioinformatics: 8,194
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    • Site-wide: 17,346
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    • Site-wide: 710

From multiplex serology to serolomics: A novel approach to the antibody response against the SARS-CoV-2 proteome

epidemiology more details view paper
  • Downloaded 319 times
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    • Site-wide: 95,382
    • In epidemiology: 4,021
  • Year to date:
    • Site-wide: 53,246
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    • Site-wide: None

Trans-ethnic genome-wide meta-analysis of 35,732 cases and 34,424 controls identifies novel genomic cross-ancestry loci contributing to lung cancer susceptibility

epidemiology more details view paper
  • Downloaded 314 times
  • Download rankings, all-time:
    • Site-wide: 96,723
    • In epidemiology: 4,069
  • Year to date:
    • Site-wide: 37,247
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    • Site-wide: 84,311

Genetic architectures of proximal and distal colorectal cancer are partly distinct

genetic and genomic medicine more details view paper
  • Downloaded 283 times
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    • Site-wide: 103,835
    • In genetic and genomic medicine: 505
  • Year to date:
    • Site-wide: 82,079
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    • Site-wide: 67,012

The effect of sample size on polygenic hazard models for prostate cancer

genetics more details view paper
  • Downloaded 262 times
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    • Site-wide: 109,044
    • In genetics: 4,607
  • Year to date:
    • Site-wide: 142,945
  • Since beginning of last month:
    • Site-wide: 57,232

The association between low-density lipoprotein cholesterol predicted by HMGCR genetic variants and breast cancer risk may be mediated by body mass index

epidemiology more details view paper
  • Downloaded 238 times
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    • Site-wide: 115,032
    • In epidemiology: 4,824
  • Year to date:
    • Site-wide: 129,228
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    • Site-wide: 56,914

Effects of Screening for Colorectal Cancer: Development, Documentation and Validation of a Multistate Markov Model

epidemiology more details view paper
  • Downloaded 233 times
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    • Site-wide: 116,088
    • In epidemiology: 4,885
  • Year to date:
    • Site-wide: 95,466
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    • Site-wide: 99,392

A combined proteomics and Mendelian randomization approach to investigate the effects of aspirin-targeted proteins on colorectal cancer

cancer biology more details view paper
  • Downloaded 216 times
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    • Site-wide: 120,606
    • In cancer biology: 3,659
  • Year to date:
    • Site-wide: 88,934
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The association between weight at birth and breast cancer risk revisited using Mendelian randomisation

epidemiology more details view paper
  • Downloaded 215 times
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    • Site-wide: 120,744
    • In epidemiology: 5,076
  • Year to date:
    • Site-wide: 140,255
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Strong reduction of distal colorectal cancer incidence and mortality but no reduction of proximal colon cancer after screening colonoscopy: prospective cohort study

epidemiology more details view paper
  • Downloaded 194 times
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    • Site-wide: 125,919
    • In epidemiology: 5,295
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    • Site-wide: 87,098
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    • Site-wide: 39,416

Rare copy number variants (CNVs) and breast cancer risk

genetics more details view paper
  • Downloaded 165 times
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    • Site-wide: 132,768
    • In genetics: 5,386
  • Year to date:
    • Site-wide: 41,693
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    • Site-wide: 16,200

Additional SNPs improve the performance of a polygenic hazard score for prostate cancer

genetic and genomic medicine more details view paper
  • Downloaded 158 times
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    • Site-wide: 134,503
    • In genetic and genomic medicine: 743
  • Year to date:
    • Site-wide: 106,820
  • Since beginning of last month:
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Strongly Divergent Impact of Adherence Patterns on Efficacy of Colorectal Cancer Screening: The Need to Refine Adherence Statistics

epidemiology more details view paper
  • Downloaded 118 times
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    • Site-wide: 142,968
    • In epidemiology: 5,903
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    • Site-wide: 123,725
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Association of the inflammation-related proteome with dementia development at older age: results from a large, prospective, population-based cohort study

epidemiology more details view paper
  • Downloaded 92 times
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    • Site-wide: 147,634
    • In epidemiology: 6,094
  • Year to date:
    • Site-wide: 75,029
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    • Site-wide: 91,614

The mediating role of epigenetic clocks underlying educational inequalities in mortality: a multi-cohort study

epidemiology more details view paper
  • Downloaded 89 times
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    • Site-wide: 148,047
    • In epidemiology: 6,117
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Prostate cancer risk stratification improved across multiple ancestries with new polygenic hazard score

genetic and genomic medicine more details view paper
  • Downloaded 6 times
  • Download rankings, all-time:
    • Site-wide: 154,868
    • In genetic and genomic medicine: 946
  • Year to date:
    • Site-wide: 154,761
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