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Results 1 through 20 out of 103

in category surgery

 

1: Surgical site infection and its associated factors in Ethiopia: A systematic review and meta-analysis

Wondimeneh Shibabaw Shiferaw, Yared Asmare Aynalem et al.

149 downloads (posted 30 Dec 2019)

BackgroundDespite being a preventable complication of surgical procedures, surgical site infections (SSIs) continue to threaten public health with significant impacts on the patients and the health-care human and financial resources. With millions affected globally, there issignificant variation in the primary studies on the prevalence of SSIs in Ethiopia. Therefore, this study aimed to estimate the pooled prevalence of SSI and its associated factors among postoperative patients in Ethiopia. MethodsPubMed, Scopus, Psyinfo, African Journals Online, and Google Scholar were searched for studies that looked at SSI in postoperative patients. A funnel plot and Eggers regression test were used to determine publication bias. The I2 statistic was used to check heterogeneity between the studies. DerSimonian and Laird random-effects model was applied to estimate the pooled effect size, odds ratios (ORs), and 95% confidence interval (CIs) across studies. The subgroup analysis was conducted by region, sample size, and year of publication. Sensitivity analysis was deployed to determine the effect of a single study on the overall estimation. Analysis was done using STATA Version 14 software. ResultA total of 24 studies with 13,136 study participants were included in this study. The estimated pooled prevalence of SSI in Ethiopia was 12.3% (95% CI: 10.19, 14.42). Duration of surgery > 1 hour (AOR = 1.78; 95% CI: 1.08 -2.94), diabetes mellitus (AOR = 3.25; 95% CI: 1.51-6.99), American Society of Anaesthesiologists score >1 (AOR = 2.51; 95% CI: 1.07-5.91), previous surgery (AOR = 2.5; 95% CI: 1.77-3.53), clean-contaminated wound (AOR = 2.15; 95% CI: 1.52-3.04), and preoperative hospital stay > 7 day (AOR = 5.76; 95% CI: 1.15-28.86), were significantly associated with SSI. ConclusionThe prevalence of SSI among postoperative patients in Ethiopia remains high with a pooled prevalence of 12.3% in 24 extracted studies. Therefore, situation based interventions and region context-specific preventive strategies should be developed to reduce the prevalence of SSI among postoperative patients.

https://rxivist.org/papers/106494
https://doi.org/10.1101/2019.12.25.19015792

2: Internal Neurolysis for the Treatment of Trigeminal Neuralgia: Systematic Review

Victor Sabourin, Pascal Lavergne et al.

132 downloads (posted 26 May 2021)

Introduction Trigeminal neuralgia remains a challenging disease with significant debilitating symptoms and variable efficacy in terms of treatment options, namely microvascular decompression (MVD), stereotactic radiosurgery (SRS), and percutaneous rhizotomy. Internal neurolysis (IN) is an alternative treatment that may be provide patient benefit but has limited understanding. We performed a systematic review of IN treatment of trigeminal neuralgia. Methods Studies from 2000 to 2021 that assessed IN in trigeminal neuralg...

https://rxivist.org/papers/143352
https://doi.org/10.1101/2021.05.25.21257791

3: Environmental impact and life cycle financial cost of hybrid (reusable/ single-use) instruments versus single-use equivalents in laparoscopic cholecystectomy

Chantelle Rizan, Mahmood F Bhutta

126 downloads (posted 12 Mar 2021)

BackgroundHybrid surgical instruments contain both single-use and reusable components, potentially bringing together advantages from both approaches. MethodsWe used Life Cycle Assessment to evaluate environmental impact of hybrid laparoscopic clip appliers, scissors and ports used for a laparoscopic cholecystectomy, comparing these with single-use equivalents. We modelled this using SimaPro to determine 18 midpoint environmental impacts including the carbon footprint, and three aggregated endpoint impacts. We also cond...

https://rxivist.org/papers/133020
https://doi.org/10.1101/2021.03.10.21253268

4: Racial and Ethnic Inequities in Mortality During Hospitalization for Traumatic Brain Injury: A Call to Action

Emma A Richie, Joseph G Nugent et al.

122 downloads (posted 09 Apr 2021)

The health disparities which drive inequities in health outcomes have long plagued our already worn healthcare system and are often dismissed as being a result of social determinants of health. Herein, we explore the nature of these inequities by comparing outcomes for racial and ethnic minority patients suffering from traumatic brain injury (TBI). We retrospectively reviewed all patients enrolled in the Trauma One Database at the Oregon Health & Science University Hospital from 2006 to October 2017 with an abbreviated ...

https://rxivist.org/papers/137207
https://doi.org/10.1101/2021.04.06.21254905

5: The St. Gallen 2019 Guidelines understages the Axilla in Lobular Breast Cancer a Population-Based Study

Ulrik Narbe, Par-Ola Bendahl et al.

118 downloads (posted 12 Jun 2021)

Background The St. Gallen 2019 guidelines recommend omission of completion axillary lymph node dissection (cALND) in breast cancer patients with 1-2 sentinel lymph node (SLN) metastases regardless of histopathology. Concurrently, adjuvant chemotherapy is endorsed for luminal A-like disease with [≥]4 axillary lymph node (ALN) metastases. We aimed to estimate the proportion of patients with invasive lobular cancer (ILC) and invasive ductal cancer of no special type (NST) and 1-2 SLN metastases for whom cALND would indi...

https://rxivist.org/papers/145826
https://doi.org/10.1101/2021.06.08.21258532

6: Timing of cholecystectomy after percutaneous cholecystectomy for acute cholecystitis- A systematic review and meta-analysis

BHAVIN VASAVADA, Hardik Patel

116 downloads (posted 12 Jun 2021)

Introduction: There is a controversy about the optimum timing of cholecystectomy after percutaneous cholecystostomy. This systematic review and meta-analysis aimed to evaluate outcomes of early versus late cholecystectomy after percutaneous cholecystectomy. Methods: The study was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement and MOOSE guidelines. Heterogeneity was measured using Q tests and I2 statistics. The random-effects model was used. We evaluated c...

https://rxivist.org/papers/145827
https://doi.org/10.1101/2021.06.06.21258426

7: Impact of the COVID-19 pandemic on surgical procedures in Brazil: a descriptive study

Barbara Okabaiasse Luizeti, Victor Augusto Santos Perli et al.

106 downloads (posted 20 Mar 2021)

Background: The COVID-19 pandemic has deeply affected medical practice, and changes in healthcare activities were needed to minimize the overload and avoid healthcare systems collapse. The aim of this study was to evaluate the impact of the pandemic on surgical procedures in Brazil. Materials and Methods: We conducted a descriptive study of the number of hospitalizations for surgical procedures in Brazil from 2016 to 2020. Data were collected from the Brazilian Department of Informatics of the Unified Health System (DAT...

https://rxivist.org/papers/134234
https://doi.org/10.1101/2021.03.17.21253801

8: Effects of Acute Normovolemic Hemodilution on Post-Cardiopulmonary Bypass Coagulation Tests and Allogeneic Blood Transfusion in Thoracic Aortic Repair Surgery: An Observational Cohort Study

Domagoj Mladinov, Kyle W Eudailey et al.

105 downloads (posted 03 Jun 2021)

Background and Aim: Perioperative blood transfusion is associated with increased morbidity and mortality. Acute normovolemic hemodilution (ANH) is a blood conservation strategy associated with variable success, and rarely studied in more complex cardiac procedures. The study aim was to evaluate whether acute ANH improves coagulopathy and reduces blood transfusions in thoracic aortic surgeries. Methods: Single-center observational cohort study comparing ANH and standard institutional practice in patients who underwent th...

https://rxivist.org/papers/144643
https://doi.org/10.1101/2021.06.01.21258155

9: Laser speckle contrast imaging for visualizing blood flow during cerebral aneurysm surgery: A comparison with indocyanine green angiography

David R Miller, Ramsey Ashour et al.

102 downloads (posted 29 Apr 2021)

Laser speckle contrast imaging (LSCI) has emerged as a promising tool for intraoperative cerebral blood flow (CBF) monitoring because it produces real-time full-field blood flow maps non-invasively and label-free. In this study, we compare LSCI with indocyanine green angiography (ICGA) to assess CBF during aneurysm clipping surgery in humans. LSCI hardware was attached to the surgical microscope prior to the start of each surgery and did not interfere with the sterile draping of the microscope or normal operation of the...

https://rxivist.org/papers/140186
https://doi.org/10.1101/2021.04.29.21254954

10: Management Algorithm of External Fixation in Lower Leg Arterial Injury for Limb Salvages

Lei Jin, Song Zhang et al.

96 downloads (posted 03 Mar 2021)

PurposeThe purpose of this study was to review the roles of using external fixation to rescue the patients who sustained arterial injuries in the lower legs. MethodsDemographics, surgical treatment and outcomes in 88 patients with lower leg arterial injuries treated by external fixation at two trauma centers from 2009 to 2018 were reviewed. The primary outcome was the rate of successful lower leg salvage, while secondary outcomes were complications and functional recovery. Results80 patients (90 legs) maintained a suc...

https://rxivist.org/papers/132316
https://doi.org/10.1101/2021.03.01.21252666

11: Mortality after surgery with SARS-CoV-2 infection in England: A population-wide epidemiological study

T E Abbott, A J Fowler et al.

96 downloads (posted 20 Feb 2021)

ObjectivesTo confirm the incidence of perioperative SARS-CoV-2 infection and associated mortality after surgery. Design and settingAnalysis of routine electronic health record data from National Health Service (NHS) hospitals in England. MethodsWe extracted data from Hospital Episode Statistics in England describing adult patients undergoing surgery between 1st January 2020 and 31st October 2020. The exposure was SARS-CoV-2 infection defined by ICD-10 codes. The primary outcome measure was 90-day in-hospital mortality...

https://rxivist.org/papers/131192
https://doi.org/10.1101/2021.02.17.21251928

12: Surgical activity in England and Wales during the COVID-19 pandemic: a nationwide observational cohort study

T. D. Dobbs, J A G Gibson et al.

88 downloads (posted 01 Mar 2021)

ObjectivesTo report the volume of surgical activity and the number of cancelled surgical procedures during the COVID-19 pandemic. Design and settingAnalysis of electronic health record data from the National Health Service (NHS) in England and Wales. MethodsWe used hospital episode statistics for all adult patients undergoing surgery between 1st January 2020 and 31st December 2020. We identified surgical procedures using a previously published list of procedure codes. Procedures were stratified by urgency of surgery a...

https://rxivist.org/papers/132212
https://doi.org/10.1101/2021.02.27.21252593

13: Outcomes following out-of-hours cholecystectomy: A systematic review and meta-analysis

Sameer Bhat, Chris Varghese et al.

83 downloads (posted 05 Feb 2021)

Background: Cholecystectomy is one of the most commonly performed abdominal operations. Demands on acute operating theatre availability have led to out-of-hours (evenings, nights, or weekend) cholecystectomy being performed, although it is not known whether outcomes differ between out-of-hours and in-hours (daytime on weekdays) cholecystectomy. Objective: This systematic review and meta-analysis aimed to compare outcomes following out-of-hours versus in-hours urgent cholecystectomy. Methods: MEDLINE, EMBASE and Scopus d...

https://rxivist.org/papers/128262
https://doi.org/10.1101/2021.02.03.21251096

14: Postoperative morbidity after liver resection- A Systemic review, meta-analysis, and metaregression of factors affecting them.

BHAVIN VASAVADA, HARDIK PATEL

83 downloads (posted 09 Apr 2021)

Aim of the study: This systemic review and meta-analysis aimed to analyze post-operative morbidity after liver resection, and also study various factors associated with mortality via metaregression analysis. Material and Methods: PubMed, Cochrane Library, Embase, google scholar, web of science with keywords like liver resection; mortality; hepatectomy. Weighted percentage post-operative morbidities were analyzed. Meta-analysis and meta-regression were done by the DerSimonian-Liard random effect model. Heterogeneity was ...

https://rxivist.org/papers/137208
https://doi.org/10.1101/2021.04.06.21254984

15: Tissue Stress from Laparoscopic Grasper Use and Bowel Injury in Humans: Establishing Intraoperative Force Boundaries

Amanda Farah Khan, Matthew Kenneth MacDonald et al.

82 downloads (posted 23 Feb 2021)

BackgroundInappropriate force in laparoscopic surgery can lead to inadvertent tissue injury. It is currently unknown however at what magnitude of compressive stress trauma occurs in gastrointestinal tissues. MethodsThis study included 10 small bowel and 10 colon samples. Each was compressed with pressures ranging from 100 kPa to 600 kPa by a novel device to induce compressive "grasps" to simulate those of a laparoscopic grasper. Experimentation was performed ex-vivo, in-vitro. Grasp conditions of 0 to 600 kPa for a dur...

https://rxivist.org/papers/131251
https://doi.org/10.1101/2021.02.19.21252109

16: Place of preperitoneal pelvic packing in severe pelvic traumatisms: About 20 cases performed in a French military level one trauma center

Hardy Julie, Coisy Marie et al.

79 downloads (posted 15 Feb 2021)

BackgroundThe overall mortality of hemodynamically unstable pelvic fractures is high. Hemorrhage triggers off the Moore lethal triad. Hemostatic management during the golden hour is essential. Combined with pelvic stabilisation, preperitoneal pelvic packing (PPP) is proposed to control venous and bony bleeding, while arterioembolisation can stop arterial bleeding. No international consensus has yet prioritized these procedures. The aim of this study was to analyse a serie of PPP in a military level one trauma center and...

https://rxivist.org/papers/130170
https://doi.org/10.1101/2021.02.09.21250850

17: Recent trends in postoperative mortality after liver resection- A systemic review and metanalysis of studies published in last 5 years and metaregression of various factors affecting 90 days mortality.

BHAVIN VASAVADA, hardik patel

79 downloads (posted 29 Mar 2021)

Aim: The aim of this systemic review and meta-analysis was to analyse 90 days mortality after liver resection, and also study various factors associated with mortality via univariate and multivariate metaregression. Methods: PubMed, Cochrane library, Embase, google scholar, web of science with keywords like liver resection, mortalit, hepatectomy. Weighted percentage 90 days mortalities were analysed. univariate metaregression was done by DerSimonian-Liard methods. Major hepatectomy, open surgery, cirrhotic livers, blood...

https://rxivist.org/papers/135540
https://doi.org/10.1101/2021.03.26.21254407

18: A propensity score matched study: Predictive signs of anastomotic leakage after gastric cancer surgery and the role of CT

Birendra Kumar Sah, Yang Zhang et al.

78 downloads (posted 29 Apr 2020)

Background: Anastomotic leakage is a critical postoperative complication after gastric cancer surgery. Previous studies have not specified radiological findings of anastomotic leakage. We investigated the potential burden caused by postoperative anastomotic leakage and explored the objective appearances of anastomotic leakage on computed tomography (CT) examination. Methods: Gastric cancer patients who underwent curative gastrectomy and had a CT examination after surgery were included in this study. Propensity score (PS...

https://rxivist.org/papers/109535
https://doi.org/10.1101/2020.04.25.20080093

19: Impact of gastric resection and enteric anastomotic configuration on delayed gastric emptying after pancreaticoduodenectomy: a network meta-analysis of randomized trials

Chris Varghese, Sameer Bhat et al.

78 downloads (posted 25 Jan 2021)

Introduction Delayed gastric emptying (DGE) is frequent after pancreaticoduodenectomy (PD). Several randomised controlled trials (RCTs) have explored operative strategies to minimise DGE, however, the optimal combination of gastric resection approach, anastomotic route, and configuration, role of Braun enteroenterostomy remains unclear. Methods MEDLINE, Embase, and CENTRAL databases were systematically searched for RCTs comparing gastric resection (Classic Whipple, pylorus-resecting, and pylorus-preserving), anastomotic...

https://rxivist.org/papers/126478
https://doi.org/10.1101/2021.01.24.21250401

20: Research priorities for lower limb amputation in patients with vascular disease

David Bosanquet, Sandip Nandhra et al.

74 downloads (posted 24 May 2021)

Introduction Lower limb amputation is a life-changing event for patients and can be associated with high mortality and morbidity rates. Research into this critical part of vascular surgery is limited. The Vascular Society of Great Britain and Ireland (VSGBI) in partnership with the James Lind Alliance (JLA) process, aimed to identify and develop key research priorities for amputation. Methods A modified JLA Priority Setting Partnership was undertaken, encompassing all vascular practice. Two separate Delphi processes to ...

https://rxivist.org/papers/143048
https://doi.org/10.1101/2021.05.21.21256746